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Tag Content
iUUCD ID IUUC-Xtr-132473
Ensembl Protein ID ENSXETP00000047766.3
UniProt Accession Q6DEP7; SUMO1_XENTR
Genbank Protein ID AAH77048.1
Protein Name Small ubiquitin-related modifier 1
Genbank Nucleotide ID BC077048
Gene Name sumo1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSXETG00000022072.3 ENSXETT00000047766.3 ENSXETP00000047766.3
Status Unreviewed
Classification
Family E-Value Score Start End
ULD/UBL/SUMO 2.10e-30 105.5 21 98
ULD/UDP/UBQ/UBQ_Other 8.00e-07 29.0 29 96
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   ULD/UBL/SUMO
   S: 7    apvslkvagqdGsevlfklklsaqlkklmeavYvkrinldensvrfvfngqkireqetpeelevededkiellcqksGG 85
            +++lkv gqd+se++fk+k++++lkkl+e+ Y++r+++ +ns+rf+f+gq+i++++tp+el++e+ed+ie++++++GG
   Q: 21   DYIKLKVIGQDSSEIHFKVKMTTHLKKLKES-YCQRQGVPMNSLRFLFEGQRISDHQTPKELGMEEEDVIEVYQEQTGG 98
           589****************************.**********************************************9 PP
   

   ULD/UDP/UBQ/UBQ_Other
   S: 7    sldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekks 74
             d+se  +kv+ ++  ++LKe   +++g+p+++ r +++G+ + d++t +++g+ ++++i +++++ 
   Q: 29   GQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRISDHQTPKELGMEEEDVIEVYQEQT 96
           445557778899999*************************************************9875 PP
   
Organism Xenopus tropicalis
Functional Description
(View)

Functional Description


     Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex sae1-sae2 and linkage to the E2 enzyme ube2i. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric sumo1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins (By similarity).
 Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex sae1-sae2 and linkage to the E2 enzyme ube2i. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric sumo1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins (By similarity).
Protein Sequence
(Fasta)
MSDQEAKPSS EDLGDKKEGG DYIKLKVIGQ DSSEIHFKVK MTTHLKKLKE SYCQRQGVPM 60
NSLRFLFEGQ RISDHQTPKE LGMEEEDVIE VYQEQTGGHS TI 102
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Protein Fasta Sequence


>IUUC-Xtr-132473|ULD,UBQ_Other;ULD,SUMO|Xenopus tropicalis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ACACCTTCCT TGTCTGGTTC TCTTGTGCTG TTATTGTGCC CGGAGGAAGG AAAAGCGTAG 60
AGCGGTCCAG TGTAGCGAAC CGATACCGGC CGAGAGCAGT TAGCATGTCT GATCAGGTGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Xtr-132473|ULD,UBQ_Other;ULD,SUMO|Xenopus tropicalis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1017--Isopeptide bond
KW-0472--Membrane
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
Interpro

IPR022617--Rad60/SUMO-like_dom
IPR033950--Sumo
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
PROSITE

PS50053--UBIQUITIN_2
Pfam

PF11976--Rad60-SLD
SMART

SM00213--UBQ
Gene Ontology

GO:0005737--C:cytoplasm
GO:0097165--C:nuclear stress granule
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0031386--F:protein tag
GO:0008134--F:transcription factor binding
GO:0071276--P:cellular response to cadmium ion
GO:0034605--P:cellular response to heat
GO:0043009--P:chordate embryonic development
GO:0060216--P:definitive hemopoiesis
GO:0016925--P:protein sumoylation
KEGG xtr:448691
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001056 Aegilops tauschii 41.07 2.00e-18 83.60
IUUC-Aml-001606 Ailuropoda melanoleuca 93.94 4.00e-50 188.00
IUUC-Apl-003638 Anas platyrhynchos 92.93 8.00e-50 187.00
IUUC-Aca-004710 Anolis carolinensis 92.16 2.00e-50 189.00
IUUC-Aly-006343 Arabidopsis lyrata 52.94 5.00e-21 91.70
IUUC-Ath-007391 Arabidopsis thaliana 53.49 1.00e-21 94.40
IUUC-Ago-007749 Ashbya gossypii 53.25 2.00e-18 83.60
IUUC-Ame-011662 Astyanax mexicanus 83.84 4.00e-43 165.00
IUUC-Bta-013491 Bos taurus 93.14 8.00e-52 194.00
IUUC-Bra-017542 Brassica rapa 53.49 1.00e-21 94.40
IUUC-Cel-018251 Caenorhabditis elegans 58.43 1.00e-28 117.00
IUUC-Cja-019109 Callithrix jacchus 90.20 4.00e-50 188.00
IUUC-Cfa-020657 Canis familiaris 94.12 6.00e-52 194.00
IUUC-Cpo-022508 Cavia porcellus 93.88 1.00e-49 186.00
IUUC-Cre-022970 Chlamydomonas reinhardtii 44.55 3.00e-20 89.40
IUUC-Csa-023026 Chlorocebus sabaeus 92.16 2.00e-41 160.00
IUUC-Cho-024767 Choloepus hoffmanni 94.44 5.00e-37 145.00
IUUC-Cne-027072 Cryptococcus neoformans 51.52 7.00e-16 74.70
IUUC-Dre-028383 Danio rerio 82.65 4.00e-42 161.00
IUUC-Dno-029820 Dasypus novemcinctus 93.14 8.00e-52 194.00
IUUC-Ete-032782 Echinops telfairi 71.43 1.00e-32 130.00
IUUC-Eca-033958 Equus caballus 94.12 6.00e-52 194.00
IUUC-Eeu-034822 Erinaceus europaeus 94.00 7.00e-51 191.00
IUUC-Fca-035601 Felis catus 93.94 5.00e-50 188.00
IUUC-Fal-036740 Ficedula albicollis 92.93 1.00e-49 187.00
IUUC-Gmo-038847 Gadus morhua 91.18 2.00e-33 132.00
IUUC-Gga-040129 Gallus gallus 93.14 8.00e-52 194.00
IUUC-Gac-042112 Gasterosteus aculeatus 85.71 2.00e-44 169.00
IUUC-Ggo-045413 Gorilla gorilla 93.14 8.00e-52 194.00
IUUC-Hsa-046108 Homo sapiens 93.14 8.00e-52 194.00
IUUC-Itr-047968 Ictidomys tridecemlineatus 94.06 2.00e-51 192.00
IUUC-Kpa-049243 Komagataella pastoris 44.68 2.00e-13 67.00
IUUC-Lch-049881 Latimeria chalumnae 84.69 9.00e-39 150.00
IUUC-Loc-052189 Lepisosteus oculatus 88.66 7.00e-46 174.00
IUUC-Laf-053478 Loxodonta africana 91.92 2.00e-49 186.00
IUUC-Mcc-055059 Macaca mulatta 61.07 6.00e-43 166.00
IUUC-Meu-056112 Macropus eugenii 91.18 8.00e-51 192.00
IUUC-Mtr-057985 Medicago truncatula 47.96 3.00e-22 95.90
IUUC-Mla-059030 Melampsora laricipopulina 37.50 2.00e-08 50.80
IUUC-Mga-060035 Meleagris gallopavo 92.93 5.00e-50 187.00
IUUC-Mmr-060903 Microcebus murinus 93.14 8.00e-52 194.00
IUUC-Mdo-062633 Monodelphis domestica 91.18 6.00e-51 191.00
IUUC-Mmu-063272 Mus musculus 93.14 8.00e-52 194.00
IUUC-Mpu-066505 Mustela putorius furo 92.93 2.00e-49 186.00
IUUC-Mlu-067991 Myotis lucifugus 90.20 2.00e-45 173.00
IUUC-Nle-069344 Nomascus leucogenys 94.52 9.00e-38 147.00
IUUC-Opr-070351 Ochotona princeps 48.04 4.00e-16 76.60
IUUC-Ont-071436 Oreochromis niloticus 85.71 2.00e-44 169.00
IUUC-Oan-072986 Ornithorhynchus anatinus 92.73 4.00e-24 101.00
IUUC-Ocu-073781 Oryctolagus cuniculus 91.18 1.00e-50 190.00
IUUC-Ola-086373 Oryzias latipes 83.67 8.00e-43 164.00
IUUC-Olu-087670 Ostreococcus lucimarinus 45.71 7.00e-17 78.20
IUUC-Oga-088024 Otolemur garnettii 83.33 3.00e-46 176.00
IUUC-Oar-089991 Ovis aries 91.18 4.00e-50 188.00
IUUC-Ptr-090688 Pan troglodytes 91.18 1.00e-50 190.00
IUUC-Pan-092204 Papio anubis 93.14 8.00e-52 194.00
IUUC-Psi-093396 Pelodiscus sinensis 92.93 7.00e-50 187.00
IUUC-Pfo-096306 Poecilia formosa 83.17 1.00e-43 167.00
IUUC-Pab-098393 Pongo abelii 93.14 7.00e-52 196.00
IUUC-Pop-099655 Populus trichocarpa 50.00 4.00e-21 92.40
IUUC-Pca-100237 Procavia capensis 92.16 8.00e-50 188.00
IUUC-Pva-102353 Pteropus vampyrus 92.50 5.00e-39 152.00
IUUC-Rno-105286 Rattus norvegicus 93.14 8.00e-52 194.00
IUUC-Sce-106231 Saccharomyces cerevisiae 46.94 7.00e-19 84.70
IUUC-Sha-106712 Sarcophilus harrisii 93.06 1.00e-36 144.00
IUUC-Sja-107710 Schizosaccharomyces japonicus 49.48 5.00e-22 95.50
IUUC-Spo-108261 Schizosaccharomyces pombe 51.55 4.00e-22 96.30
IUUC-Sit-110664 Setaria italica 32.50 3.00e-08 50.40
IUUC-Sly-111005 Solanum lycopersicum 52.22 2.00e-20 89.70
IUUC-Stu-112200 Solanum tuberosum 50.56 1.00e-20 90.50
IUUC-Sar-113550 Sorex araneus 91.84 1.00e-48 183.00
IUUC-Sre-115172 Sporisorium reilianum 51.81 2.00e-20 89.40
IUUC-Ssc-115837 Sus scrofa 89.22 2.00e-50 189.00
IUUC-Tgu-117064 Taeniopygia guttata 92.86 2.00e-49 186.00
IUUC-Tru-117752 Takifugu rubripes 85.71 1.00e-44 170.00
IUUC-Tsy-119358 Tarsius syrichta 92.11 3.00e-36 143.00
IUUC-Tni-120621 Tetraodon nigroviridis 85.71 4.00e-44 168.00
IUUC-Tae-124177 Triticum aestivum 47.42 2.00e-21 93.60
IUUC-Tbe-127355 Tupaia belangeri 71.43 1.00e-32 130.00
IUUC-Ttr-128166 Tursiops truncatus 93.14 5.00e-51 192.00
IUUC-Uma-129444 Ustilago maydis 49.44 8.00e-21 90.90
IUUC-Vpa-130172 Vicugna pacos 93.14 7.00e-52 195.00
IUUC-Xma-133814 Xiphophorus maculatus 84.16 2.00e-44 170.00
Created Date 25-Jun-2017

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