iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gma-042656

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

CM000839

Gene Name

LOC100816664; GLYMA_06G255000

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GLYMA06G39770	GLYMA06G39770.1	GLYMA06G39770.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.30e-53	181.8	313	807
UBD/Alpha-Helix/UBA	6.20e-16	59.6	623	663

Active Site

Position(s)	Description	Evidence
322	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
770	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelre.lllekkkeklneenpkepkgellkslqklfeel.....................w.kskkkavspr 71
           tGl N+gN+CYm +++Q+ ++++++++ ++l++  +k  e +p +p+ +l ++l+kl + +                     + + k++ + p+
   Q: 313  TGLVNIGNSCYMAATIQVVFSTRSFTSrYYLNQSLKKAFEMSPADPTVDLNMQLTKLAHGIlsgkysvpafendekenvatsTrTAKQEGIRPH 406
           7************************8625666677777777889*****************8888888888888887776542677888***** PP
   S: 72   ellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssr 165
           ++++++++ ++efs+++qqDa Ef+ ++ldq+e++                            + k++   s+ F++ ++++i c +  +v+  
   Q: 407  MFKSVIAASHPEFSSTQQQDALEFFLHFLDQVERAN---------------------------TGKTELDPSRSFKFGIEDRILCSSG-KVTYN 472
           *********************************988...........................5567777899************765.55555 PP
   S: 166  eepfldlslpvpgkeetkke.............................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevL 230
           + + + lsl++p +e t++e                              l+ cL +f+++ee+++   +y++  k+k++a k+ +l+++P++L
   Q: 473  RRNDYILSLNIPLHEATNEEelesfhklkaeklaegkeinaneivrprvPLETCLVNFSAPEEIQD---FYSTALKAKTTALKTAGLTSFPDYL 563
           55667888888887777777889*****************************************97...************************* PP
   S: 231  ilhLkRfsfseeqksrekinkkvefpleLdlspfcts.....peekqke............................................. 274
           +lh+ Rf + e++  ++k++ ++++p+ +d+s++ ++     +     e                                             
   Q: 564  VLHMRRF-VMEAGREPKKLDVHIDVPDIIDISHMRSKgqqsgE-----Ellpdgvpgeqdsnkisaneeivaqlvsmgfnhlhcqkaaintsnv 651
           *******.678899******************99999444440.....3555555555666666666666666666666666666677777777 PP
   S: 275  .............................................................................................. 274
                                                                                                         
   Q: 652  gveeamnwllshmddpdidnpiskghgsetivdqskvdilisfgfeeeiarnalkasggdiekatdwifnnpdasvssmdaspsnaesttndvn 745
           7777777777777777777777777777777777777777777777777777888888888888888888888888888888888888999999 PP
   S: 275  ....kkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
                 kY+L+++++HsG sl++GHYva++ + +g+W  f+D+kV ++   +  +   + +Y++f++r
   Q: 746  lpdgGGKYRLMGILSHSGtSLQCGHYVAHILK-DGRWAIFNDNKVGAS--IDPPK---EMGYLYFFER 807
           9999****************************.9***********998..46666...7899999886 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           ++e++++qlv+MGF+  ++++a  ++ n  +e+A+++Ll++
   Q: 623  ANEEIVAQLVSMGFNHLHCQKAAINTsNVGVEEAMNWLLSH 663
           79*************************************97 PP

Organism

Glycine max

Protein Sequence
(Fasta)

MTIEPMDLLR SYLSRVRIPE PTNRIYKHEC CISFDSPRSE GGLFIDMCTF LAFGKDFVGW 60
NYEKTGNPVY LHIKQTKKLV PEDRPSKKPT LLAIGVDGGF DNNEPEYEET HSVVILPEYV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGACAGGTT AATTAGCTGT TCACACACCG TCCACTTTTA AAACCCCCAT TTCCATTGCA 60
GCAGCATAAA GAAGCATACT CAATCGAAGC AAAGCACCTA GTGAAAGTGA GACTCTGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

gmx:100816664

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Afl-008547	Aspergillus flavus	35.54	8.00e-110	391.00
IUUC-Aor-010111	Aspergillus oryzae	33.90	8.00e-120	424.00
IUUC-Cme-027335	Cyanidioschyzon merolae	33.45	2.00e-37	151.00
IUUC-Pte-104306	Pyrenophora teres	35.19	2.00e-92	333.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence