iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-060148

UUCD1 version

UUC-MeG-00860

Ensembl Protein ID

ENSMGAP00000008765.2

UniProt Accession

G1N8T7; G1N8T7_MELGA

Protein Name

Uncharacterized protein

Gene Name

USP7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000008497.2	ENSMGAT00000009569.2	ENSMGAP00000008765.2
ENSMGAG00000008497.2	ENSMGAT00000020113.1	ENSMGAP00000018106.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.10e-68	230.7	198	504

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +GlkN+g+tCYmNS+LQ+L+++++lr+++    + +      +++++++  +lq++f el ++++k v +++l+k++++e   +++++q
   Q: 198  VGLKNQGATCYMNSLLQTLFFTNQLRKAVYM-MPTEG-----DDSSKSVPLALQRVFYEL-QHSDKPVGTKKLTKSFGWET--LDSFMQ 277
           6******************************.44433.....466889************.88889************887..67**** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +D+qE++++lld++e+++                          k +  + +i +lF+g++ s i+c++ d +s+r e+ +d++l+++g
   Q: 278  HDVQELCRVLLDNVENKM--------------------------KGTCVEGTIPKLFRGKMVSYIQCKHVDYRSERIEDYYDIQLSIKG 340
           ******************..........................789****************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
           k+     ++ +++ ++++ e+l+g+nky   +  ++qeaek +k+ +lP+vL+l+L+Rf ++ ++++++kin+++efp++L l++f+++
   Q: 341  KK-----NIFESFIDYVAVEQLDGDNKYDAGEH-GLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQK 423
           **.....9*********************9996.7****************************************************** PP
   S: 268  peekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg............staYvlfYkr 337
           ++ k+  + +Y L+av+vHsG  ++GHYv+y +   +gkW++fdD+ V+ +++ee  e +             ++aY+l+Y r
   Q: 424  TDPKD--PANYILHAVLVHSGDNHGGHYVVYLNPkGDGKWCKFDDDVVSRCTKEEAIEHNYgghdddlsvrhcTNAYMLVYIR 504
           88777..*************************9834566************86666664446*******************87 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

TAGQSYLRVL AGDADDPPRI TQNPVINGNV AMADGHNNTE EDMEDDTSWR SEATFQFTVE 60
RFNRLSESVL SPPCFVRNLP WKIMVMPRLY PDRPHQKSVG FFLQCNAESD STSWSCHAQA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGCAGGAC AAAGTTATTT ACGAGGTCAT TTTCACTTTG AGACTTGGTT TTGAAATTCT 60
GAGTGTAAGG CCATTAGAAG CTTAAGAATG CTGGCGTTCT CTGTTAATAC GGGCTTTTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002083--MATH/TRAF_dom
IPR001394--Peptidase_C19_UCH
IPR008974--TRAF-like
IPR024729--USP7_ICP0-binding_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50144--MATH
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00917--MATH
PF00443--UCH
PF14533--USP7_C2
PF12436--USP7_ICP0_bdg

SMART

SM00061--MATH

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0010216--P:maintenance of DNA methylation
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0050821--P:protein stabilization
GO:0006283--P:transcription-coupled nucleotide-excision repair
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000761	Aegilops tauschii	33.24	7.00e-143	501.00
IUUC-Aml-002408	Ailuropoda melanoleuca	96.68	0.00e+00	2184.00
IUUC-Atr-003067	Amborella trichopoda	37.17	3.00e-124	439.00
IUUC-Apl-003558	Anas platyrhynchos	99.81	0.00e+00	2249.00
IUUC-Aca-004518	Anolis carolinensis	92.72	0.00e+00	2088.00
IUUC-Aly-006453	Arabidopsis lyrata	37.10	5.00e-160	558.00
IUUC-Ath-007610	Arabidopsis thaliana	36.82	5.00e-156	545.00
IUUC-Ago-007849	Ashbya gossypii	32.73	5.00e-140	491.00
IUUC-Acl-008327	Aspergillus clavatus	34.60	3.00e-173	602.00
IUUC-Afl-008491	Aspergillus flavus	35.06	2.00e-167	582.00
IUUC-Afu-008804	Aspergillus fumigatus	35.35	1.00e-164	573.00
IUUC-Ang-009776	Aspergillus niger	35.46	1.00e-164	573.00
IUUC-Aor-009998	Aspergillus oryzae	34.32	6.00e-159	554.00
IUUC-Ate-010428	Aspergillus terreus	35.10	3.00e-167	582.00
IUUC-Ame-010903	Astyanax mexicanus	94.09	0.00e+00	2140.00
IUUC-Bgr-012132	Blumeria graminis	32.19	1.00e-147	516.00
IUUC-Bta-013192	Bos taurus	96.58	0.00e+00	2179.00
IUUC-Bci-013924	Botrytis cinerea	34.32	7.00e-155	541.00
IUUC-Bdi-014920	Brachypodium distachyon	35.75	6.00e-157	548.00
IUUC-Bol-015224	Brassica oleracea	36.86	7.00e-157	547.00
IUUC-Bra-017448	Brassica rapa	36.64	1.00e-156	546.00
IUUC-Cel-018219	Caenorhabditis elegans	34.04	6.00e-157	548.00
IUUC-Cja-019006	Callithrix jacchus	95.40	0.00e+00	2152.00
IUUC-Cfa-020361	Canis familiaris	96.77	0.00e+00	2185.00
IUUC-Cpo-022320	Cavia porcellus	96.58	0.00e+00	2176.00
IUUC-Cre-022708	Chlamydomonas reinhardtii	44.26	4.00e-92	331.00
IUUC-Csa-024050	Chlorocebus sabaeus	97.12	0.00e+00	2181.00
IUUC-Cho-024434	Choloepus hoffmanni	88.38	0.00e+00	1410.00
IUUC-Cin-025689	Ciona intestinalis	54.87	0.00e+00	1222.00
IUUC-Csv-025963	Ciona savignyi	53.58	0.00e+00	1173.00
IUUC-Cgl-026650	Colletotrichum gloeosporioides	33.66	4.00e-154	538.00
IUUC-Cne-026968	Cryptococcus neoformans	36.56	0.00e+00	637.00
IUUC-Cme-027103	Cyanidioschyzon merolae	35.82	1.00e-116	414.00
IUUC-Dre-028510	Danio rerio	94.37	0.00e+00	2144.00
IUUC-Dno-029696	Dasypus novemcinctus	96.31	0.00e+00	2171.00
IUUC-Dor-030611	Dipodomys ordii	81.04	0.00e+00	944.00
IUUC-Dse-031433	Dothistroma septosporum	34.16	6.00e-149	521.00
IUUC-Dme-031583	Drosophila melanogaster	48.68	0.00e+00	1042.00
IUUC-Ete-033191	Echinops telfairi	94.47	0.00e+00	2131.00
IUUC-Eca-034122	Equus caballus	96.41	0.00e+00	2179.00
IUUC-Eeu-035292	Erinaceus europaeus	82.85	0.00e+00	673.00
IUUC-Fca-036377	Felis catus	96.68	0.00e+00	2183.00
IUUC-Fal-036964	Ficedula albicollis	99.91	0.00e+00	2208.00
IUUC-Fox-037695	Fusarium oxysporum	33.94	1.00e-163	570.00
IUUC-Fso-038084	Fusarium solani	33.91	1.00e-162	567.00
IUUC-Gmo-038644	Gadus morhua	93.96	0.00e+00	2138.00
IUUC-Ggr-040029	Gaeumannomyces graminis	33.79	2.00e-160	559.00
IUUC-Gga-040944	Gallus gallus	100.00	0.00e+00	2241.00
IUUC-Gac-041740	Gasterosteus aculeatus	94.42	0.00e+00	2144.00
IUUC-Gma-043300	Glycine max	36.82	1.00e-168	587.00
IUUC-Ggo-044947	Gorilla gorilla	96.50	0.00e+00	2182.00
IUUC-Hsa-046278	Homo sapiens	96.93	0.00e+00	2178.00
IUUC-Hvu-047749	Hordeum vulgare	36.93	4.00e-141	494.00
IUUC-Itr-047904	Ictidomys tridecemlineatus	97.00	0.00e+00	1873.00
IUUC-Kpa-049121	Komagataella pastoris	31.03	2.00e-127	450.00
IUUC-Lch-049847	Latimeria chalumnae	97.40	0.00e+00	2197.00
IUUC-Lpe-051543	Leersia perrieri	35.42	8.00e-150	524.00
IUUC-Loc-052234	Lepisosteus oculatus	94.84	0.00e+00	1434.00
IUUC-Lma-053169	Leptosphaeria maculans	36.68	1.00e-167	583.00
IUUC-Laf-053566	Loxodonta africana	97.21	0.00e+00	2180.00
IUUC-Mcc-055549	Macaca mulatta	96.85	0.00e+00	2177.00
IUUC-Meu-056887	Macropus eugenii	88.11	0.00e+00	1277.00
IUUC-Mor-057149	Magnaporthe oryzae	35.05	6.00e-163	568.00
IUUC-Mpo-057536	Magnaporthe poae	33.88	3.00e-161	562.00
IUUC-Mtr-058583	Medicago truncatula	37.46	8.00e-165	574.00
IUUC-Mla-058899	Melampsora laricipopulina	37.60	2.00e-174	606.00
IUUC-Mvi-060207	Microbotryum violaceum	37.52	0.00e+00	637.00
IUUC-Mmr-060946	Microcebus murinus	97.21	0.00e+00	2184.00
IUUC-Mdo-062079	Monodelphis domestica	90.93	0.00e+00	1979.00
IUUC-Mmu-063678	Mus musculus	96.56	0.00e+00	2166.00
IUUC-Mac-065416	Musa acuminata	37.55	2.00e-156	546.00
IUUC-Mpu-066744	Mustela putorius furo	97.25	0.00e+00	2139.00
IUUC-Mlu-067949	Myotis lucifugus	96.13	0.00e+00	2162.00
IUUC-Nfi-068342	Neosartorya fischeri	35.26	1.00e-164	573.00
IUUC-Ncr-068818	Neurospora crassa	34.60	1.00e-163	570.00
IUUC-Nle-070064	Nomascus leucogenys	97.03	0.00e+00	2180.00
IUUC-Opr-071001	Ochotona princeps	95.31	0.00e+00	1801.00
IUUC-Ont-072095	Oreochromis niloticus	94.09	0.00e+00	2142.00
IUUC-Oan-073483	Ornithorhynchus anatinus	98.10	0.00e+00	2145.00
IUUC-Ocu-073967	Oryctolagus cuniculus	96.27	0.00e+00	2093.00
IUUC-Oba-075811	Oryza barthii	34.33	7.00e-141	494.00
IUUC-Obr-076857	Oryza brachyantha	36.00	5.00e-154	538.00
IUUC-Ogl-077038	Oryza glaberrima	35.73	5.00e-150	525.00
IUUC-Ogu-078265	Oryza glumaepatula	34.22	1.00e-136	481.00
IUUC-Oin-079513	Oryza indica	35.41	5.00e-142	498.00
IUUC-Olo-081067	Oryza longistaminata	34.29	6.00e-139	488.00
IUUC-Ome-081879	Oryza meridionalis	36.22	8.00e-151	527.00
IUUC-Oni-082461	Oryza nivara	34.74	2.00e-146	512.00
IUUC-Opu-083199	Oryza punctata	35.80	4.00e-147	515.00
IUUC-Oru-085109	Oryza rufipogon	35.54	2.00e-146	513.00
IUUC-Osa-085418	Oryza sativa	39.11	2.00e-131	462.00
IUUC-Ola-086640	Oryzias latipes	94.33	0.00e+00	2136.00
IUUC-Olu-087874	Ostreococcus lucimarinus	33.04	5.00e-144	505.00
IUUC-Oga-089059	Otolemur garnettii	89.58	0.00e+00	1989.00
IUUC-Oar-089710	Ovis aries	96.50	0.00e+00	2179.00
IUUC-Ptr-091334	Pan troglodytes	96.50	0.00e+00	2182.00
IUUC-Pan-091717	Papio anubis	97.32	0.00e+00	2117.00
IUUC-Psi-093933	Pelodiscus sinensis	98.61	0.00e+00	2232.00
IUUC-Pma-094648	Petromyzon marinus	83.38	0.00e+00	1738.00
IUUC-Pno-095020	Phaeosphaeria nodorum	35.26	1.00e-151	530.00
IUUC-Ppa-096020	Physcomitrella patens	35.00	2.00e-162	566.00
IUUC-Pfo-096181	Poecilia formosa	93.81	0.00e+00	2138.00
IUUC-Pab-098231	Pongo abelii	94.01	0.00e+00	2109.00
IUUC-Pop-099680	Populus trichocarpa	37.31	5.00e-160	558.00
IUUC-Pca-100543	Procavia capensis	80.16	0.00e+00	1008.00
IUUC-Ppe-101523	Prunus persica	36.32	3.00e-154	538.00
IUUC-Pva-102472	Pteropus vampyrus	95.48	0.00e+00	2133.00
IUUC-Pgr-103463	Puccinia graminis	37.25	1.00e-173	603.00
IUUC-Ptt-103716	Puccinia triticina	38.23	2.00e-170	592.00
IUUC-Pte-104360	Pyrenophora teres	36.32	1.00e-152	533.00
IUUC-Pyt-104581	Pyrenophora triticirepentis	35.94	5.00e-151	528.00
IUUC-Rno-105816	Rattus norvegicus	96.56	0.00e+00	2172.00
IUUC-Sce-106230	Saccharomyces cerevisiae	30.19	6.00e-126	445.00
IUUC-Sha-107439	Sarcophilus harrisii	98.14	0.00e+00	2190.00
IUUC-Sja-107690	Schizosaccharomyces japonicus	33.30	1.00e-142	500.00
IUUC-Spo-108019	Schizosaccharomyces pombe	34.63	2.00e-145	509.00
IUUC-Smo-109308	Selaginella moellendorffii	36.09	8.00e-154	537.00
IUUC-Sit-110367	Setaria italica	36.19	3.00e-157	549.00
IUUC-Sly-111774	Solanum lycopersicum	36.70	1.00e-165	577.00
IUUC-Stu-112387	Solanum tuberosum	37.41	5.00e-165	575.00
IUUC-Sar-113685	Sorex araneus	95.85	0.00e+00	2160.00
IUUC-Sbi-114037	Sorghum bicolor	37.05	3.00e-157	549.00
IUUC-Sre-115156	Sporisorium reilianum	37.14	0.00e+00	644.00
IUUC-Ssc-116297	Sus scrofa	97.12	0.00e+00	2181.00
IUUC-Tgu-116767	Taeniopygia guttata	99.63	0.00e+00	2245.00
IUUC-Tru-118208	Takifugu rubripes	93.77	0.00e+00	2107.00
IUUC-Tsy-119277	Tarsius syrichta	86.21	0.00e+00	700.00
IUUC-Tni-119890	Tetraodon nigroviridis	93.68	0.00e+00	2109.00
IUUC-Tca-121696	Theobroma cacao	36.60	3.00e-155	542.00
IUUC-Tre-122169	Trichoderma reesei	33.55	3.00e-155	542.00
IUUC-Tvi-122600	Trichoderma virens	34.12	3.00e-163	569.00
IUUC-Tae-125264	Triticum aestivum	35.82	1.00e-154	540.00
IUUC-Tur-126287	Triticum urartu	35.22	6.00e-149	521.00
IUUC-Tme-127045	Tuber melanosporum	35.43	2.00e-168	585.00
IUUC-Tbe-127696	Tupaia belangeri	86.32	1.00e-157	550.00
IUUC-Ttr-129161	Tursiops truncatus	96.77	0.00e+00	2178.00
IUUC-Uma-129535	Ustilago maydis	37.19	0.00e+00	658.00
IUUC-Vda-129708	Verticillium dahliae	33.24	6.00e-162	564.00
IUUC-Vvi-131048	Vitis vinifera	35.88	3.00e-158	552.00
IUUC-Xtr-132073	Xenopus tropicalis	93.14	0.00e+00	2090.00
IUUC-Xma-133949	Xiphophorus maculatus	93.72	0.00e+00	2133.00
IUUC-Yli-134527	Yarrowia lipolytica	33.48	2.00e-139	489.00
IUUC-Zma-135855	Zea mays	36.76	5.00e-147	514.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence