iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Smo-108819

Ensembl Protein ID

EFJ08647

UniProt Accession

D8T3R4; D8T3R4_SELML

Genbank Protein ID

EFJ08647.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

GL377671

Gene Name

SELMODRAFT_447957

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SELMODRAFT_447957	EFJ08647	EFJ08647

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-39	132.1	50	86
UBD/Beta-Prp	7.50e-79	265.7	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f s+ +l+vsG+dD +ikvW+++  ++l
   Q: 50   HDGPVRGVHFhSSqPLFVSGGDDYKIKVWNYKARRCL 86
           99*********767****************9887776 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
           t +++++++++ + f+p++++++++  +g i +wd+++g+l+ ++ +h+++v+ v f+++++++v+g++D+ ikvw+++++ c+ tl gh d++++++f++
   Q: 3    TTFETKSNRVKGLSFHPKRPWILASLHTGVIHLWDYRMGSLIDRFDEHDGPVRGVHFHSSQPLFVSGGDDYKIKVWNYKARRCLFTLLGHLDYIRTVQFHQ 103
           77889999********************************************************************************************* PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.........................ktgkllrtl.tggh 179
           +  ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+++h +++l+vs+slD+tvr+Wd+                           g+++ +   +gh
   Q: 104  EYPWIVSASDDQTIRIWNWQSRTCVS-VLTGHNHYVMCASFHVKDDLVVSASLDQTVRVWDIsslrkktvspaedllmltqmnsdlfGGGDVVVKYvLEGH 203
           **************************.****************************************999999999988888777774444444436555* PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdn 278
           ++ v++ +f+++ + +vsg++d++vklw +  ++   v+tl+ght+nv++v f+ +++++vs s+D++ir+Wdl ++  ++t+ + +++++ +++ +++ n
   Q: 204  DRGVNWAAFHPSLPLIVSGADDRQVKLWRINDTKAweVDTLRGHTNNVSCVLFHARQDIIVSNSEDKTIRVWDLSKRSAVQTFRRDHDRFWVICG-HPEMN 303
           *******************************777668*********************************************************9.66666 PP
   S: 279  vlvlgsedskvniwklkknep 299
            l++g  ds + ++kl++++p
   Q: 304  LLAAG-HDSGIIVFKLERERP 323
           55554.689999***998775 PP

Organism

Selaginella moellendorffii

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTTFETKSN RVKGLSFHPK RPWILASLHT GVIHLWDYRM GSLIDRFDEH DGPVRGVHFH 60
SSQPLFVSGG DDYKIKVWNY KARRCLFTLL GHLDYIRTVQ FHQEYPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGACGA CGTTCGAGAC GAAGAGCAAT CGCGTCAAGG GCCTGAGCTT CCATCCCAAG 60
CGGCCATGGA TCTTGGCCAG TCTCCACACC GGCGTCATTC ATCTGTGGGA TTACCGGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

KEGG

smo:SELMODRAFT_447957

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ath-007058	Arabidopsis thaliana	67.27	0.00e+00	1661.00
IUUC-Pop-099992	Populus trichocarpa	67.92	0.00e+00	1680.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence