iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005170

UUCD1 version

UUC-AnC-00495

Ensembl Protein ID

ENSACAP00000002663.2

UniProt Accession

G1KB43; G1KB43_ANOCA

Protein Name

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4

Gene Name

WDR4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000002741.3	ENSACAT00000002730.3	ENSACAP00000002663.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.10e-06	26.6	188	224

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd..tllvsGsdDgtikvWDlrtgv 34
           gHt+ v+ + f  ++  +ll+s+s+D+t+++W+++ g+
   Q: 188  GHTEFVSRI-FviPNypDLLLSASGDCTLRLWEYKHGK 224
           678878888.888444799**************98776 PP

Organism

Anolis carolinensis

Functional Description
(View)

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Protein Sequence
(Fasta)

RETPAGAGAP GGLLALTGGT RLLAARLKEP SHDDLFVYDC ATASKTPQEK QGKDIKSSGK 60
ASHDILACAF SSSGTYFSLT DDNKQLILFR TKPAWECLSI RSVIRRCTSL IITATEDKIL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTCAATGCA GTCATGCCAG CCACATGACC TTGGAGGTGT CTACGGACAA CGCCGGCTCT 60
TCGGCTTAGA AATTGAGATG AGCACCAACC CCCAGAGTCG GACGCAACTA GACTTAATGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0043527--C:tRNA methyltransferase complex
GO:0008176--F:tRNA (guanine-N7-)-methyltransferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000556	Aegilops tauschii	27.49	8.00e-09	54.70
IUUC-Atr-002431	Amborella trichopoda	41.18	9.00e-06	42.40
IUUC-Apl-003975	Anas platyrhynchos	65.85	5.00e-129	454.00
IUUC-Aly-005769	Arabidopsis lyrata	35.03	7.00e-16	78.20
IUUC-Ath-006733	Arabidopsis thaliana	35.03	9.00e-16	77.80
IUUC-Acl-008151	Aspergillus clavatus	46.38	9.00e-11	61.60
IUUC-Afl-008518	Aspergillus flavus	47.69	5.00e-11	61.60
IUUC-Afu-009102	Aspergillus fumigatus	34.86	8.00e-11	61.60
IUUC-Ani-009442	Aspergillus nidulans	40.54	2.00e-09	57.00
IUUC-Aor-010133	Aspergillus oryzae	47.69	5.00e-11	62.40
IUUC-Ate-010465	Aspergillus terreus	43.28	3.00e-10	59.70
IUUC-Ame-010613	Astyanax mexicanus	42.72	1.00e-81	296.00
IUUC-Bgr-012067	Blumeria graminis	35.34	9.00e-14	71.60
IUUC-Bta-012788	Bos taurus	53.53	3.00e-112	398.00
IUUC-Bdi-014458	Brachypodium distachyon	31.88	3.00e-12	66.20
IUUC-Bol-016398	Brassica oleracea	30.67	3.00e-18	86.30
IUUC-Bra-016644	Brassica rapa	35.12	1.00e-16	82.40
IUUC-Cpo-021963	Cavia porcellus	49.60	3.00e-97	348.00
IUUC-Csa-024148	Chlorocebus sabaeus	53.47	5.00e-96	344.00
IUUC-Cne-026834	Cryptococcus neoformans	38.19	8.00e-14	72.00
IUUC-Dre-028427	Danio rerio	45.39	2.00e-85	309.00
IUUC-Dno-028881	Dasypus novemcinctus	48.42	1.00e-102	366.00
IUUC-Dor-030522	Dipodomys ordii	51.03	1.00e-114	405.00
IUUC-Dme-032136	Drosophila melanogaster	34.62	2.00e-19	89.70
IUUC-Fca-035833	Felis catus	53.42	2.00e-107	382.00
IUUC-Fal-037497	Ficedula albicollis	68.64	7.00e-129	453.00
IUUC-Gga-040547	Gallus gallus	66.41	1.00e-131	462.00
IUUC-Gac-041761	Gasterosteus aculeatus	42.90	4.00e-73	268.00
IUUC-Gma-043722	Glycine max	35.47	2.00e-14	73.20
IUUC-Ggo-045340	Gorilla gorilla	52.72	3.00e-100	358.00
IUUC-Hsa-046403	Homo sapiens	52.72	7.00e-100	357.00
IUUC-Hvu-047643	Hordeum vulgare	30.65	2.00e-15	77.00
IUUC-Itr-048103	Ictidomys tridecemlineatus	52.62	2.00e-108	385.00
IUUC-Kpa-049283	Komagataella pastoris	26.40	1.00e-11	64.30
IUUC-Lch-050682	Latimeria chalumnae	51.51	8.00e-101	360.00
IUUC-Lpe-050712	Leersia perrieri	34.48	3.00e-19	89.40
IUUC-Loc-052599	Lepisosteus oculatus	53.05	5.00e-113	400.00
IUUC-Laf-054390	Loxodonta africana	53.41	1.00e-115	409.00
IUUC-Mcc-054747	Macaca mulatta	53.47	1.00e-99	356.00
IUUC-Mtr-058600	Medicago truncatula	30.90	1.00e-18	87.40
IUUC-Mla-059129	Melampsora laricipopulina	25.53	8.00e-10	57.40
IUUC-Mga-059876	Meleagris gallopavo	67.84	8.00e-133	466.00
IUUC-Mvi-060359	Microbotryum violaceum	28.40	2.00e-10	60.80
IUUC-Mmr-061518	Microcebus murinus	53.90	1.00e-108	385.00
IUUC-Mac-065625	Musa acuminata	30.43	2.00e-14	73.60
IUUC-Nfi-068402	Neosartorya fischeri	33.94	2.00e-10	60.10
IUUC-Nle-069914	Nomascus leucogenys	51.73	4.00e-93	334.00
IUUC-Ont-071555	Oreochromis niloticus	41.21	5.00e-71	261.00
IUUC-Oan-072951	Ornithorhynchus anatinus	60.79	4.00e-123	434.00
IUUC-Ocu-074679	Oryctolagus cuniculus	52.07	3.00e-99	355.00
IUUC-Obr-076769	Oryza brachyantha	32.37	8.00e-19	87.80
IUUC-Ogl-077168	Oryza glaberrima	30.71	3.00e-19	89.40
IUUC-Oin-079207	Oryza indica	30.71	3.00e-19	89.40
IUUC-Opu-084031	Oryza punctata	31.30	3.00e-20	93.20
IUUC-Osa-085327	Oryza sativa	34.24	5.00e-19	88.60
IUUC-Ola-086716	Oryzias latipes	38.46	6.00e-64	237.00
IUUC-Olu-087708	Ostreococcus lucimarinus	26.29	8.00e-11	61.20
IUUC-Oar-090239	Ovis aries	53.35	3.00e-107	381.00
IUUC-Ptr-090851	Pan troglodytes	52.72	1.00e-100	359.00
IUUC-Pan-092558	Papio anubis	51.97	2.00e-95	342.00
IUUC-Psi-093792	Pelodiscus sinensis	71.50	2.00e-153	535.00
IUUC-Ppa-095757	Physcomitrella patens	34.52	3.00e-15	76.30
IUUC-Pfo-096465	Poecilia formosa	40.77	7.00e-74	270.00
IUUC-Pab-097722	Pongo abelii	53.12	8.00e-104	370.00
IUUC-Pop-098979	Populus trichocarpa	31.55	3.00e-15	75.90
IUUC-Pca-100753	Procavia capensis	53.98	1.00e-72	266.00
IUUC-Sja-107780	Schizosaccharomyces japonicus	41.56	3.00e-10	59.70
IUUC-Spo-108251	Schizosaccharomyces pombe	25.00	3.00e-08	52.80
IUUC-Smo-108938	Selaginella moellendorffii	34.05	1.00e-16	80.50
IUUC-Sit-110020	Setaria italica	32.97	6.00e-17	81.60
IUUC-Sly-111543	Solanum lycopersicum	28.52	2.00e-17	83.20
IUUC-Stu-111925	Solanum tuberosum	28.52	3.00e-17	82.80
IUUC-Sbi-114061	Sorghum bicolor	29.84	1.00e-19	90.90
IUUC-Tgu-117321	Taeniopygia guttata	66.28	4.00e-121	427.00
IUUC-Tru-118454	Takifugu rubripes	39.04	6.00e-67	247.00
IUUC-Tni-119894	Tetraodon nigroviridis	38.52	1.00e-61	229.00
IUUC-Tca-121746	Theobroma cacao	30.45	8.00e-16	78.20
IUUC-Tae-124459	Triticum aestivum	30.00	8.00e-16	77.80
IUUC-Tur-126254	Triticum urartu	28.29	4.00e-10	58.90
IUUC-Tbe-127683	Tupaia belangeri	37.10	1.00e-36	147.00
IUUC-Ttr-129056	Tursiops truncatus	51.09	6.00e-101	360.00
IUUC-Vvi-131428	Vitis vinifera	33.15	1.00e-15	77.00
IUUC-Xma-133605	Xiphophorus maculatus	42.75	1.00e-77	283.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence