iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133605

Ensembl Protein ID

ENSXMAP00000009484.1

UniProt Accession

M4A4U0; M4A4U0_XIPMA

Genbank Protein ID

ENSXMAP00000009484

Protein Name

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4

Genbank Nucleotide ID

AGAJ01036498

Gene Name

wdr4; WDR4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000009462.1	ENSXMAT00000009498.1	ENSXMAP00000009484.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-06	28.5	190	225

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 6    vtclaf....sdtllvsGsdDgtikvWDlrtgvllks 38
           v+ l+     + + l+sGs+Dgt+k+W++ +g++l+s
   Q: 190  VSTLEIpkghP-HWLLSGSGDGTVKLWEFESGRKLQS 225
           55555555322.669******************9986 PP

Organism

Xiphophorus maculatus

Functional Description
(View)

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Protein Sequence
(Fasta)

MACLGFCGEW FLSTCSSKLI AIHTKEPREL FVFDCSHAEK RLKIAKDVNS SDASEDTGSD 60
TVLAFAVSSS GKLMAITDDT KRLILFQCEP SWHCISIRWV IRRCTSLVFS PAEDELLVAD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGATCATC CCCGCATTCT CCACGTGGAA GACAAGAACT AAGAGCATTC AGTTCGGTAC 60
CGTGAGCAAT GGCTTGTTTG GGTTTCTGTG GGGAATGGTT TCTGTCAACC TGCAGCAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0036265--P:RNA (guanine-N7)-methylation
GO:0030488--P:tRNA methylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002431	Amborella trichopoda	32.03	1.00e-10	58.50
IUUC-Apl-003975	Anas platyrhynchos	44.81	4.00e-86	311.00
IUUC-Aca-005170	Anolis carolinensis	43.91	7.00e-71	261.00
IUUC-Aly-005769	Arabidopsis lyrata	28.57	2.00e-22	100.00
IUUC-Ath-006733	Arabidopsis thaliana	27.82	3.00e-21	96.30
IUUC-Acl-008151	Aspergillus clavatus	29.30	6.00e-17	82.00
IUUC-Afl-008518	Aspergillus flavus	33.33	2.00e-17	83.60
IUUC-Afu-009102	Aspergillus fumigatus	29.96	1.00e-16	80.90
IUUC-Ani-009442	Aspergillus nidulans	26.20	1.00e-13	70.90
IUUC-Aor-010133	Aspergillus oryzae	26.19	6.00e-18	85.50
IUUC-Ate-010465	Aspergillus terreus	28.41	4.00e-17	82.80
IUUC-Ame-010613	Astyanax mexicanus	54.09	4.00e-113	401.00
IUUC-Bgr-012067	Blumeria graminis	35.95	5.00e-17	82.40
IUUC-Bta-012788	Bos taurus	43.32	4.00e-79	288.00
IUUC-Bdi-014458	Brachypodium distachyon	30.71	4.00e-12	65.90
IUUC-Bol-016398	Brassica oleracea	30.30	2.00e-23	103.00
IUUC-Bra-017059	Brassica rapa	31.65	2.00e-22	100.00
IUUC-Cpo-021963	Cavia porcellus	42.89	4.00e-78	285.00
IUUC-Csa-024148	Chlorocebus sabaeus	41.67	5.00e-70	258.00
IUUC-Cne-026834	Cryptococcus neoformans	32.65	4.00e-20	93.20
IUUC-Dre-028427	Danio rerio	53.55	7.00e-119	420.00
IUUC-Dno-028881	Dasypus novemcinctus	36.10	2.00e-63	236.00
IUUC-Dor-030522	Dipodomys ordii	41.54	5.00e-79	288.00
IUUC-Dme-032136	Drosophila melanogaster	37.57	3.00e-22	99.40
IUUC-Fca-035833	Felis catus	44.77	2.00e-78	286.00
IUUC-Fal-037497	Ficedula albicollis	44.90	3.00e-84	305.00
IUUC-Gga-040547	Gallus gallus	44.64	9.00e-85	306.00
IUUC-Gac-041761	Gasterosteus aculeatus	59.04	8.00e-129	453.00
IUUC-Gma-043722	Glycine max	29.05	6.00e-19	88.60
IUUC-Ggo-045340	Gorilla gorilla	42.74	1.00e-74	273.00
IUUC-Hsa-046403	Homo sapiens	42.74	9.00e-75	273.00
IUUC-Hvu-047643	Hordeum vulgare	28.18	6.00e-14	72.00
IUUC-Itr-048103	Ictidomys tridecemlineatus	42.78	1.00e-81	296.00
IUUC-Kpa-049283	Komagataella pastoris	31.49	5.00e-18	85.50
IUUC-Lch-050682	Latimeria chalumnae	41.88	9.00e-81	293.00
IUUC-Lpe-050712	Leersia perrieri	30.07	5.00e-21	95.50
IUUC-Loc-052599	Lepisosteus oculatus	50.52	8.00e-113	400.00
IUUC-Laf-054390	Loxodonta africana	42.25	6.00e-81	294.00
IUUC-Mcc-054747	Macaca mulatta	42.74	6.00e-73	268.00
IUUC-Mtr-058600	Medicago truncatula	34.07	5.00e-22	98.60
IUUC-Mla-059135	Melampsora laricipopulina	27.00	3.00e-13	70.10
IUUC-Mga-059876	Meleagris gallopavo	45.66	3.00e-86	311.00
IUUC-Mvi-060359	Microbotryum violaceum	28.65	1.00e-10	61.60
IUUC-Mmr-061518	Microcebus murinus	41.44	2.00e-75	276.00
IUUC-Mac-065625	Musa acuminata	28.70	6.00e-23	102.00
IUUC-Nfi-068402	Neosartorya fischeri	26.85	4.00e-17	82.80
IUUC-Nle-069914	Nomascus leucogenys	41.13	1.00e-67	249.00
IUUC-Ont-071555	Oreochromis niloticus	61.54	5.00e-132	464.00
IUUC-Oan-072951	Ornithorhynchus anatinus	43.13	4.00e-82	298.00
IUUC-Ocu-074679	Oryctolagus cuniculus	41.27	1.00e-73	270.00
IUUC-Oba-075355	Oryza barthii	26.43	6.00e-10	58.90
IUUC-Obr-076769	Oryza brachyantha	30.58	1.00e-20	94.40
IUUC-Ogl-077168	Oryza glaberrima	30.16	2.00e-21	97.10
IUUC-Ogu-078275	Oryza glumaepatula	26.11	1.00e-09	57.80
IUUC-Oin-079207	Oryza indica	30.16	2.00e-21	97.10
IUUC-Oni-082437	Oryza nivara	28.30	9.00e-10	58.20
IUUC-Opu-084031	Oryza punctata	31.58	9.00e-20	91.70
IUUC-Oru-084380	Oryza rufipogon	26.43	9.00e-10	58.20
IUUC-Osa-085327	Oryza sativa	30.16	2.00e-21	96.70
IUUC-Ola-086716	Oryzias latipes	56.43	5.00e-121	427.00
IUUC-Olu-087708	Ostreococcus lucimarinus	27.03	7.00e-14	71.60
IUUC-Oar-090239	Ovis aries	43.35	2.00e-79	289.00
IUUC-Ptr-090851	Pan troglodytes	42.74	9.00e-75	273.00
IUUC-Pan-092558	Papio anubis	41.18	2.00e-68	252.00
IUUC-Psi-093792	Pelodiscus sinensis	40.05	5.00e-80	291.00
IUUC-Ppa-095757	Physcomitrella patens	31.68	2.00e-21	97.10
IUUC-Pfo-096465	Poecilia formosa	91.77	0.00e+00	748.00
IUUC-Pab-097722	Pongo abelii	43.66	1.00e-75	276.00
IUUC-Pop-098979	Populus trichocarpa	30.80	1.00e-18	87.40
IUUC-Pca-100753	Procavia capensis	42.86	8.00e-54	204.00
IUUC-Ppe-101515	Prunus persica	30.90	9.00e-19	88.20
IUUC-Sja-107780	Schizosaccharomyces japonicus	26.20	5.00e-11	62.40
IUUC-Spo-108251	Schizosaccharomyces pombe	26.67	1.00e-15	77.80
IUUC-Smo-108938	Selaginella moellendorffii	30.37	3.00e-18	86.30
IUUC-Sit-110020	Setaria italica	28.53	2.00e-17	83.20
IUUC-Sly-111543	Solanum lycopersicum	31.74	3.00e-21	96.70
IUUC-Stu-111925	Solanum tuberosum	30.96	4.00e-23	102.00
IUUC-Sbi-114061	Sorghum bicolor	30.86	3.00e-18	86.30
IUUC-Tgu-117321	Taeniopygia guttata	45.09	1.00e-78	286.00
IUUC-Tru-118454	Takifugu rubripes	56.95	5.00e-121	427.00
IUUC-Tni-119894	Tetraodon nigroviridis	55.43	1.00e-104	373.00
IUUC-Tca-121746	Theobroma cacao	32.19	2.00e-23	103.00
IUUC-Tae-124459	Triticum aestivum	28.82	2.00e-15	77.40
IUUC-Tur-126254	Triticum urartu	27.17	8.00e-10	58.20
IUUC-Tbe-127683	Tupaia belangeri	53.01	3.00e-21	96.30
IUUC-Ttr-129056	Tursiops truncatus	40.64	2.00e-71	263.00
IUUC-Vvi-131428	Vitis vinifera	32.50	1.00e-22	100.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence