iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066895

Ensembl Protein ID

ENSMPUP00000007408.1

UniProt Accession

M3Y7V1; M3Y7V1_MUSPF

Genbank Protein ID

ENSMPUP00000007408

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01062802

Gene Name

UBA2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000007464.1	ENSMPUT00000007528.1	ENSMPUP00000007408.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.90e-137	458.9	10	421

Active Site

Position(s)	Description	Evidence
173	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR039133-1, ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 11   eaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesite 99
           e  e++   +vl+vGagg+GcEllKnLvl+G+++i ++D dt++vsnlnrqFLf++++vg+sKA+va+e++ ++ p+ n+ a+++si++
   Q: 10   ELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIIAYHDSIMN 98
           56799999********************************************************************************* PP
   S: 100  leeeivFfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtie 188
           ++++++Ff++f +V++aldnr+ar++vnr+cl+a+vpliesgt G+lGqv++i kg+tecy+c+++p+q+t+P+ct+++tp+++ h+i+
   Q: 99   PDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIV 187
           ***************************************************************************************** PP
   S: 189  wa.vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv. 274
           wa +lfn+l++ee++++ev++  d++++e+++++ ++e+++++++++ ++++i++k++ak+t ++ +k ++k f++di++  ++++++ 
   Q: 188  WAkYLFNQLFGEEDADQEVSP--DRADPEASWEPMEAEARARASNEDGDIKRISTKEWAKSTGYDpVKLFTKLFKDDIRYLLTMDKLWr 274
           *********************..799*************************************************************** PP
   S: 275  .................sfcsnaealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekdddsavdlvtaaan 341
                            +  + ++++++p+ ++kd++v++++++     +++++++++++ek +g    el ++kdd+sa+d+vt+aan
   Q: 275  krkppvpldwaevqsqgEETNASDQQNEPQLGLKDQQVLDVKSYaclfsKSIETLRVNLAEKGDGA---ELIWDKDDPSAMDFVTSAAN 360
           ****************999999**************************99***************9...68****************** PP
   S: 342  lraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfda 403
           lr++ +++++  ++++ik++agniipaiattnav++Gl+++E +K++sgk ++++++fl+++
   Q: 361  LRMHIFSMNM-KSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQ 421
           **********.***********************************************9965 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MALSRGLPRE LAEAVAGGRV LVVGAGGIGC ELLKNLVLTG FSHIDLIDLD TIDVSNLNRQ 60
FLFQKKHVGR SKAQVAKESV LQFYPKANII AYHDSIMNPD YNVEFFRQFI LVMNALDNRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCCCACTG AGCAGATATG TGGGGCTCAA TCCCAGGGCT CTGGGATCAT GACCCGAGCT 60
AAGGCAGAGG CTTTAACCCA CTGAGCCACC CAGGAGCCCC ATAAGTGAAA AAAATTTTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016040--NAD(P)-bd_dom
IPR030661--SAE2/Uba2
IPR000594--ThiF_NAD_FAD-bd
IPR028077--UAE_UbL_dom
IPR032426--UBA2_C
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF00899--ThiF
PF14732--UAE_UbL
PF16195--UBA2_C

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0031510--C:SUMO activating enzyme complex
GO:0019948--F:SUMO activating enzyme activity
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000112	Aegilops tauschii	38.45	5.00e-108	385.00
IUUC-Aml-001662	Ailuropoda melanoleuca	98.91	0.00e+00	1267.00
IUUC-Atr-002636	Amborella trichopoda	40.16	3.00e-112	399.00
IUUC-Apl-003369	Anas platyrhynchos	89.23	0.00e+00	1025.00
IUUC-Aca-004490	Anolis carolinensis	82.99	0.00e+00	918.00
IUUC-Aly-006359	Arabidopsis lyrata	41.94	7.00e-105	374.00
IUUC-Ath-007667	Arabidopsis thaliana	42.31	2.00e-108	386.00
IUUC-Ago-007844	Ashbya gossypii	36.74	4.00e-83	302.00
IUUC-Acl-008270	Aspergillus clavatus	41.92	1.00e-104	373.00
IUUC-Afl-008674	Aspergillus flavus	43.75	4.00e-111	395.00
IUUC-Afu-008883	Aspergillus fumigatus	41.64	2.00e-105	376.00
IUUC-Ani-009500	Aspergillus nidulans	44.96	4.00e-115	408.00
IUUC-Ang-009535	Aspergillus niger	43.65	4.00e-110	392.00
IUUC-Aor-010223	Aspergillus oryzae	44.06	3.00e-113	402.00
IUUC-Ate-010282	Aspergillus terreus	44.17	4.00e-90	325.00
IUUC-Ame-011736	Astyanax mexicanus	77.60	0.00e+00	987.00
IUUC-Bgr-012166	Blumeria graminis	41.97	7.00e-99	354.00
IUUC-Bta-012589	Bos taurus	98.44	0.00e+00	1266.00
IUUC-Bci-013802	Botrytis cinerea	43.40	9.00e-101	361.00
IUUC-Bdi-014697	Brachypodium distachyon	41.76	2.00e-111	395.00
IUUC-Bol-016315	Brassica oleracea	40.06	2.00e-111	396.00
IUUC-Bra-017009	Brassica rapa	40.52	5.00e-112	398.00
IUUC-Cel-018708	Caenorhabditis elegans	46.30	7.00e-131	460.00
IUUC-Cja-019120	Callithrix jacchus	97.97	0.00e+00	1209.00
IUUC-Cfa-021061	Canis familiaris	99.53	0.00e+00	1278.00
IUUC-Cpo-021842	Cavia porcellus	96.88	0.00e+00	1201.00
IUUC-Csa-024104	Chlorocebus sabaeus	97.97	0.00e+00	1175.00
IUUC-Cho-024332	Choloepus hoffmanni	86.33	0.00e+00	868.00
IUUC-Cin-025363	Ciona intestinalis	56.38	0.00e+00	674.00
IUUC-Cgl-026419	Colletotrichum gloeosporioides	42.33	3.00e-98	352.00
IUUC-Cne-026888	Cryptococcus neoformans	43.19	5.00e-73	268.00
IUUC-Cme-027315	Cyanidioschyzon merolae	34.20	3.00e-59	223.00
IUUC-Dre-028420	Danio rerio	75.63	0.00e+00	909.00
IUUC-Dno-030041	Dasypus novemcinctus	97.97	0.00e+00	1213.00
IUUC-Dor-031039	Dipodomys ordii	81.80	0.00e+00	644.00
IUUC-Dse-031504	Dothistroma septosporum	37.75	9.00e-94	337.00
IUUC-Dme-031771	Drosophila melanogaster	50.24	4.00e-148	518.00
IUUC-Ete-033037	Echinops telfairi	91.72	0.00e+00	1089.00
IUUC-Eca-033774	Equus caballus	98.99	0.00e+00	1217.00
IUUC-Eeu-035074	Erinaceus europaeus	98.36	0.00e+00	983.00
IUUC-Fca-036508	Felis catus	99.66	0.00e+00	1224.00
IUUC-Fal-036813	Ficedula albicollis	86.82	0.00e+00	1018.00
IUUC-Fox-038056	Fusarium oxysporum	43.78	5.00e-106	378.00
IUUC-Fso-038223	Fusarium solani	43.28	7.00e-104	371.00
IUUC-Gmo-038526	Gadus morhua	74.88	0.00e+00	896.00
IUUC-Ggr-039767	Gaeumannomyces graminis	42.97	2.00e-99	357.00
IUUC-Gga-040981	Gallus gallus	87.97	0.00e+00	1050.00
IUUC-Gac-041437	Gasterosteus aculeatus	75.84	0.00e+00	917.00
IUUC-Gma-044072	Glycine max	37.78	3.00e-113	402.00
IUUC-Ggo-045358	Gorilla gorilla	94.58	0.00e+00	1119.00
IUUC-Hsa-046068	Homo sapiens	98.12	0.00e+00	1180.00
IUUC-Hvu-047646	Hordeum vulgare	37.73	2.00e-107	383.00
IUUC-Itr-047887	Ictidomys tridecemlineatus	97.04	0.00e+00	1204.00
IUUC-Lch-049565	Latimeria chalumnae	81.34	0.00e+00	1038.00
IUUC-Lpe-050884	Leersia perrieri	40.64	5.00e-108	385.00
IUUC-Loc-052493	Lepisosteus oculatus	81.11	0.00e+00	1018.00
IUUC-Lma-053117	Leptosphaeria maculans	44.23	6.00e-101	361.00
IUUC-Laf-054518	Loxodonta africana	94.54	0.00e+00	1187.00
IUUC-Mcc-055334	Macaca mulatta	97.81	0.00e+00	1177.00
IUUC-Mor-057137	Magnaporthe oryzae	44.10	1.00e-94	340.00
IUUC-Mpo-057449	Magnaporthe poae	41.19	9.00e-102	364.00
IUUC-Mtr-058045	Medicago truncatula	40.06	1.00e-116	413.00
IUUC-Mla-058864	Melampsora laricipopulina	45.72	2.00e-95	343.00
IUUC-Mga-059422	Meleagris gallopavo	83.03	0.00e+00	928.00
IUUC-Mvi-060536	Microbotryum violaceum	42.25	2.00e-86	313.00
IUUC-Mmr-061161	Microcebus murinus	96.32	0.00e+00	1207.00
IUUC-Mdo-061802	Monodelphis domestica	92.67	0.00e+00	1140.00
IUUC-Mmu-064357	Mus musculus	93.75	0.00e+00	1194.00
IUUC-Mac-065475	Musa acuminata	39.07	2.00e-109	389.00
IUUC-Mlu-067862	Myotis lucifugus	97.97	0.00e+00	1254.00
IUUC-Nfi-068385	Neosartorya fischeri	43.24	1.00e-108	387.00
IUUC-Ncr-068885	Neurospora crassa	41.50	2.00e-107	383.00
IUUC-Nle-069524	Nomascus leucogenys	97.34	0.00e+00	1162.00
IUUC-Opr-071038	Ochotona princeps	97.03	0.00e+00	1246.00
IUUC-Ont-071719	Oreochromis niloticus	75.83	0.00e+00	977.00
IUUC-Oan-072877	Ornithorhynchus anatinus	90.57	0.00e+00	998.00
IUUC-Ocu-074080	Oryctolagus cuniculus	97.50	0.00e+00	1206.00
IUUC-Oba-075936	Oryza barthii	37.82	3.00e-108	385.00
IUUC-Obr-076841	Oryza brachyantha	37.97	9.00e-110	390.00
IUUC-Ogl-077686	Oryza glaberrima	37.87	9.00e-110	390.00
IUUC-Ogu-078597	Oryza glumaepatula	36.94	3.00e-105	375.00
IUUC-Oin-079791	Oryza indica	37.82	3.00e-108	385.00
IUUC-Olo-081009	Oryza longistaminata	37.66	4.00e-108	385.00
IUUC-Ome-081327	Oryza meridionalis	35.50	1.00e-102	367.00
IUUC-Oni-082334	Oryza nivara	37.11	2.00e-105	376.00
IUUC-Opu-083447	Oryza punctata	38.13	6.00e-110	391.00
IUUC-Oru-084977	Oryza rufipogon	39.74	1.00e-107	383.00
IUUC-Osa-086160	Oryza sativa	43.73	5.00e-95	340.00
IUUC-Ola-087415	Oryzias latipes	75.44	0.00e+00	936.00
IUUC-Olu-087850	Ostreococcus lucimarinus	41.42	5.00e-101	361.00
IUUC-Oga-088434	Otolemur garnettii	97.50	0.00e+00	1209.00
IUUC-Oar-089872	Ovis aries	98.32	0.00e+00	1212.00
IUUC-Ptr-091212	Pan troglodytes	98.12	0.00e+00	1180.00
IUUC-Pan-092708	Papio anubis	98.46	1.00e-132	466.00
IUUC-Psi-093703	Pelodiscus sinensis	90.57	0.00e+00	1051.00
IUUC-Pno-094953	Phaeosphaeria nodorum	46.76	9.00e-105	374.00
IUUC-Ppa-095963	Physcomitrella patens	44.10	2.00e-107	383.00
IUUC-Pfo-097515	Poecilia formosa	75.39	0.00e+00	931.00
IUUC-Pab-097951	Pongo abelii	97.79	0.00e+00	1023.00
IUUC-Pop-099703	Populus trichocarpa	36.70	2.00e-96	346.00
IUUC-Pca-100426	Procavia capensis	94.69	0.00e+00	1211.00
IUUC-Ppe-101152	Prunus persica	38.95	5.00e-112	398.00
IUUC-Pva-102792	Pteropus vampyrus	94.24	0.00e+00	1170.00
IUUC-Pgr-103592	Puccinia graminis	43.95	2.00e-99	356.00
IUUC-Ptt-103805	Puccinia triticina	41.70	1.00e-85	310.00
IUUC-Pte-104215	Pyrenophora teres	44.72	1.00e-111	397.00
IUUC-Pyt-104634	Pyrenophora triticirepentis	46.04	4.00e-110	392.00
IUUC-Rno-106117	Rattus norvegicus	94.38	0.00e+00	1205.00
IUUC-Sce-106177	Saccharomyces cerevisiae	36.94	2.00e-74	273.00
IUUC-Sha-107006	Sarcophilus harrisii	92.99	0.00e+00	1145.00
IUUC-Sja-107967	Schizosaccharomyces japonicus	43.05	2.00e-93	336.00
IUUC-Spo-108020	Schizosaccharomyces pombe	44.17	5.00e-97	348.00
IUUC-Ssl-108509	Sclerotinia sclerotiorum	43.26	2.00e-103	369.00
IUUC-Smo-109264	Selaginella moellendorffii	43.57	7.00e-107	380.00
IUUC-Sit-110581	Setaria italica	41.10	8.00e-109	387.00
IUUC-Sly-111870	Solanum lycopersicum	39.57	3.00e-111	395.00
IUUC-Stu-112283	Solanum tuberosum	39.87	6.00e-109	388.00
IUUC-Sar-113432	Sorex araneus	72.85	0.00e+00	810.00
IUUC-Sbi-114075	Sorghum bicolor	38.82	1.00e-108	387.00
IUUC-Sre-114926	Sporisorium reilianum	43.04	2.00e-103	370.00
IUUC-Ssc-116281	Sus scrofa	99.54	1.00e-118	418.00
IUUC-Tgu-117247	Taeniopygia guttata	85.55	0.00e+00	1014.00
IUUC-Tru-118075	Takifugu rubripes	71.20	0.00e+00	892.00
IUUC-Tsy-119398	Tarsius syrichta	81.56	0.00e+00	930.00
IUUC-Tni-120771	Tetraodon nigroviridis	66.10	0.00e+00	806.00
IUUC-Tca-121651	Theobroma cacao	39.43	6.00e-110	391.00
IUUC-Tre-122224	Trichoderma reesei	43.68	4.00e-96	345.00
IUUC-Tvi-122634	Trichoderma virens	42.91	5.00e-96	345.00
IUUC-Tae-125665	Triticum aestivum	40.56	3.00e-105	375.00
IUUC-Tur-126417	Triticum urartu	37.77	2.00e-106	379.00
IUUC-Tme-127016	Tuber melanosporum	44.44	7.00e-96	344.00
IUUC-Tbe-127678	Tupaia belangeri	82.77	2.00e-180	625.00
IUUC-Ttr-128598	Tursiops truncatus	94.53	0.00e+00	1198.00
IUUC-Uma-129612	Ustilago maydis	40.87	8.00e-97	348.00
IUUC-Vda-129811	Verticillium dahliae	40.68	3.00e-101	362.00
IUUC-Vpa-130732	Vicugna pacos	84.69	0.00e+00	1041.00
IUUC-Vvi-130832	Vitis vinifera	41.51	1.00e-105	377.00
IUUC-Xtr-132823	Xenopus tropicalis	76.29	0.00e+00	918.00
IUUC-Xma-133552	Xiphophorus maculatus	75.24	0.00e+00	931.00
IUUC-Yli-134666	Yarrowia lipolytica	37.66	5.00e-75	275.00
IUUC-Zma-135547	Zea mays	37.60	1.00e-107	384.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence