iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-034321

Ensembl Protein ID

ENSECAP00000006721.1

UniProt Accession

F6TGH5; F6TGH5_HORSE

Protein Name

Uncharacterized protein

Gene Name

FAF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000008495.1	ENSECAT00000008913.1	ENSECAP00000006721.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/UBX	2.10e-20	73.2	483	560
ULD/UDP/UBQ/UBQ_Other	4.10e-11	42.8	24	83

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfveyllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllve 80
           +++ ++l+iR+p+G++l+r+F +s++l+ +++fv+ ++++++d+F+L+s+fPrr++++ + +++l e +L+p+++l++e
   Q: 483  AEPVSKLRIRTPSGEFLERRFLASNKLQIVFDFVA-SKGFPWDEFKLLSTFPRRDVTQLDPNKSLLEVKLFPQETLFLE 560
           56799******************************.****************************************986 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL...eddktLadyglkdgstihll 70
           + ++ ++ s+tV+e+K+ +e +l ip   +++++kG      ed   L++++l+ ++ +++l
   Q: 24   NVDVVLEDSCTVGEIKQILENELQIP--VSKMLLKGWKTgdvEDSTVLKSLHLPKNNSLYVL 83
           5566678999****************..55899997776777***************99987 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MPSRQIVERQ PRMLDFRVEY RDRNVDVVLE DSCTVGEIKQ ILENELQIPV SKMLLKGWKT 60
GDVEDSTVLK SLHLPKNNSL YVLTPDLPPP SSSSHAGALQ ESLNQNFMLI ITHREVQREY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCCAGGCA TGTACTGGCA TTGAAAACAT TGATGAAGCT ATTACATTGC TTGAACAAAA 60
TAATTGGGAC TTAGTGGTAA GTGTTTGTTT CTTTTTTCAG CTTTATTAAG ATATCATTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033043--FAF1_UBX
IPR012336--Thioredoxin-like_fold
IPR006577--UAS
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50033--UBX

Pfam

PF00789--UBX

SMART

SM00594--UAS
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0005635--C:nuclear envelope
GO:0048471--C:perinuclear region of cytoplasm
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0008219--P:cell death
GO:0007253--P:cytoplasmic sequestering of NF-kappaB
GO:1902043--P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:0031334--P:positive regulation of protein complex assembly
GO:0030155--P:regulation of cell adhesion
GO:0042176--P:regulation of protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002153	Ailuropoda melanoleuca	98.93	0.00e+00	1075.00
IUUC-Apl-004127	Anas platyrhynchos	91.83	0.00e+00	1007.00
IUUC-Aca-005188	Anolis carolinensis	91.30	0.00e+00	1005.00
IUUC-Ame-010696	Astyanax mexicanus	78.51	0.00e+00	756.00
IUUC-Bta-012965	Bos taurus	98.76	0.00e+00	1073.00
IUUC-Cel-018420	Caenorhabditis elegans	28.82	2.00e-27	117.00
IUUC-Cja-019128	Callithrix jacchus	98.40	0.00e+00	1071.00
IUUC-Cfa-021201	Canis familiaris	96.67	0.00e+00	886.00
IUUC-Cpo-021475	Cavia porcellus	96.02	0.00e+00	872.00
IUUC-Csa-024076	Chlorocebus sabaeus	98.40	0.00e+00	1068.00
IUUC-Cho-025067	Choloepus hoffmanni	82.59	0.00e+00	902.00
IUUC-Cin-025663	Ciona intestinalis	43.79	7.00e-67	247.00
IUUC-Csv-025894	Ciona savignyi	35.58	3.00e-60	225.00
IUUC-Dre-027508	Danio rerio	79.68	0.00e+00	827.00
IUUC-Dno-029336	Dasypus novemcinctus	98.40	0.00e+00	1073.00
IUUC-Dor-030218	Dipodomys ordii	92.01	0.00e+00	976.00
IUUC-Dme-031581	Drosophila melanogaster	35.21	4.00e-86	312.00
IUUC-Ete-032860	Echinops telfairi	72.99	2.00e-156	545.00
IUUC-Eeu-034844	Erinaceus europaeus	75.35	3.00e-108	385.00
IUUC-Fca-036575	Felis catus	99.20	0.00e+00	711.00
IUUC-Fal-037128	Ficedula albicollis	92.18	0.00e+00	1008.00
IUUC-Gmo-038694	Gadus morhua	77.01	0.00e+00	834.00
IUUC-Gga-040826	Gallus gallus	92.36	0.00e+00	1008.00
IUUC-Gac-042125	Gasterosteus aculeatus	77.36	0.00e+00	863.00
IUUC-Ggo-045254	Gorilla gorilla	98.58	0.00e+00	1073.00
IUUC-Hsa-046722	Homo sapiens	98.40	0.00e+00	1073.00
IUUC-Hvu-047478	Hordeum vulgare	36.36	2.00e-06	47.00
IUUC-Itr-048149	Ictidomys tridecemlineatus	97.13	3.00e-95	340.00
IUUC-Lch-050312	Latimeria chalumnae	84.68	1.00e-163	568.00
IUUC-Loc-051990	Lepisosteus oculatus	84.55	0.00e+00	850.00
IUUC-Laf-054375	Loxodonta africana	98.14	0.00e+00	707.00
IUUC-Mcc-054627	Macaca mulatta	98.40	0.00e+00	1068.00
IUUC-Meu-056611	Macropus eugenii	93.02	2.00e-106	379.00
IUUC-Mga-059400	Meleagris gallopavo	92.01	0.00e+00	1005.00
IUUC-Mmr-060882	Microcebus murinus	98.22	0.00e+00	1047.00
IUUC-Mdo-061874	Monodelphis domestica	92.90	0.00e+00	1030.00
IUUC-Mmu-063444	Mus musculus	97.34	0.00e+00	1062.00
IUUC-Mpu-065713	Mustela putorius furo	98.93	0.00e+00	1076.00
IUUC-Mlu-068122	Myotis lucifugus	97.16	0.00e+00	1024.00
IUUC-Nle-069025	Nomascus leucogenys	98.22	0.00e+00	1065.00
IUUC-Opr-071089	Ochotona princeps	86.68	0.00e+00	956.00
IUUC-Ont-072421	Oreochromis niloticus	78.79	0.00e+00	845.00
IUUC-Oan-073092	Ornithorhynchus anatinus	93.33	0.00e+00	818.00
IUUC-Ola-086497	Oryzias latipes	80.00	0.00e+00	855.00
IUUC-Oga-088854	Otolemur garnettii	97.87	0.00e+00	1070.00
IUUC-Oar-090120	Ovis aries	98.93	0.00e+00	1050.00
IUUC-Ptr-091554	Pan troglodytes	98.58	0.00e+00	1073.00
IUUC-Pan-091985	Papio anubis	98.22	0.00e+00	1044.00
IUUC-Psi-093548	Pelodiscus sinensis	92.72	0.00e+00	973.00
IUUC-Pma-094123	Petromyzon marinus	51.24	1.00e-51	195.00
IUUC-Pfo-096729	Poecilia formosa	78.43	0.00e+00	845.00
IUUC-Pab-097810	Pongo abelii	98.76	0.00e+00	1076.00
IUUC-Pca-101079	Procavia capensis	89.18	0.00e+00	879.00
IUUC-Pva-102534	Pteropus vampyrus	88.05	0.00e+00	775.00
IUUC-Rno-105127	Rattus norvegicus	97.16	0.00e+00	1023.00
IUUC-Sha-106667	Sarcophilus harrisii	92.92	0.00e+00	1008.00
IUUC-Ssl-108656	Sclerotinia sclerotiorum	23.88	2.50e-02	32.30
IUUC-Sar-113424	Sorex araneus	82.83	0.00e+00	630.00
IUUC-Ssc-115974	Sus scrofa	98.57	0.00e+00	1065.00
IUUC-Tgu-116495	Taeniopygia guttata	92.18	0.00e+00	1009.00
IUUC-Tru-118727	Takifugu rubripes	76.55	0.00e+00	829.00
IUUC-Tsy-118906	Tarsius syrichta	94.67	0.00e+00	981.00
IUUC-Tni-119717	Tetraodon nigroviridis	78.07	0.00e+00	842.00
IUUC-Tur-126134	Triticum urartu	41.79	8.00e-07	48.90
IUUC-Tbe-127849	Tupaia belangeri	84.25	7.00e-177	613.00
IUUC-Ttr-128660	Tursiops truncatus	94.67	0.00e+00	1019.00
IUUC-Vpa-130359	Vicugna pacos	98.40	0.00e+00	1070.00
IUUC-Xtr-132212	Xenopus tropicalis	86.41	0.00e+00	697.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence