iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ata-000285

Ensembl Protein ID

EMT18857

UniProt Accession

N1R051; N1R051_AEGTA

Genbank Protein ID

EMT18857.1

Protein Name

Cullin-4B

Genbank Nucleotide ID

KD530717

Gene Name

F775_31987

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
F775_31987	EMT18857	EMT18857

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	1.60e-181	605.9	65	659

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 2    lreavkkilrqesvkkeyeelytavynlclskvgaklYkklkevleefi.kqvkkkveesedeq.lLktynreWekfreqlkvlrkifayldrtyvkkskk 100
           l++a+++i  ++++  + e+ly+a+ +lcl+k+ga+lY+++k+ +e +i +++++ v +s d   +L  ++r W++f+ q+ ++r i + ld +yvk   +
   Q: 65   LKDAITAIFLKQKLSCDVEKLYQAAGDLCLHKLGANLYERVKKECEIHIsAKISALVGQSPDLVvFLSLVQRTWQDFCDQMLIIRGIALLLDVKYVKNVAN 165
           799**********************************************99************99************************************ PP
   S: 101  vsevrkLaldlwrkeived..ikkrllelllklieaeRkgeavdrrllsgvveslveLslnklaiykesFEakfleatqefykaesaeflqenevdeYlkk 199
           + +v++++l+l+rk+i  +  i+++++  ll+lie+eR gea+d+ lls + +++ +L+     +y e FE++fle t+efy++e  ++lq++++ +Yl++
   Q: 166  LCSVWDMGLQLFRKHISLSpeIEHKTVTGLLRLIESERLGEAIDKTLLSHLLKMFTDLG-----MYSETFEKPFLECTSEFYATEGVKYLQQSDIPDYLRH 261
           ****************87779*************************************6.....9************************************ PP
   S: 200  vearlneeeeraaryleestetkLlevvekeliakhlesll.aelvallrdkktedlsrmykLlsrvlngleellkeleshikeqgkaaltaeekekdpkk 299
           +e+rl+ee++r+  yle+ t ++L+++ ek+l++ h  +++ +++  l++ ++  dlsrmy L++rv   +e l + l+ +i+  g+ ++++eek+kd   
   Q: 262  AESRLQEEHDRCILYLEANTRKPLIATTEKQLLQRHTSAIIeKGFTVLMEANRVTDLSRMYTLFQRVD-AIEMLKQALSLYIRGTGQGIIMDEEKDKD--- 358
           ****************************************999************************7.6899*************************... PP
   S: 300  yVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlkaakspEllAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkhL 400
            V  lle+k  l+k+++e+F ++++F ++++++fe+ +n +      + +El+A++ D++Lr+++kg+ eeele +ldkvl++f++i++kdvFe++Ykk+L
   Q: 359  LVSFLLEFKASLDKILEESFAKNEAFSNTIKESFEHLINLR----QNRPAELIAKFLDEKLRAGNKGTSEEELEGILDKVLVLFRFIQGKDVFEAFYKKDL 455
           ****************************************9....56666*************************************************** PP
   S: 401  akRLlsgksasseaEesviekLkeecgaeftskLerMfqdlkvSedlnrqFkeeken.teesesvelsvlvLsagaWptasetekvsLPaelektiekfee 500
           akRLl+gksas +aE+s+i+kLk+ecg +ft+kLe+Mf+d+++S+++n+ Fk+  ++ t+  +++e+sv vL++g+Wpt++ +  v+LP+el+ ++++f+e
   Q: 456  AKRLLLGKSASIDAEKSMITKLKTECGSQFTNKLEGMFKDIELSKEINDSFKQSSQArTKLPTGIEMSVHVLTTGYWPTYPPMD-VKLPHELNVYQDIFKE 555
           ****************************************************87765155669******************988.**************** PP
   S: 501  fYlekhsgRkLqWqhtlgraelkaelkkgkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvsskkqvlkkepeskeieeedlfsvN 601
           fYl+k sgR+L Wq +lg++ lk+e+ kg++el+Vs fQ +vL++fn+ +k+s+ ++k++t+++++eLrrtlqsL+++k +vl+k+p++++i+++d f++N
   Q: 556  FYLSKYSGRRLMWQNSLGHCVLKVEFPKGRKELAVSLFQSVVLMLFNDAQKLSFVDIKESTGIEDKELRRTLQSLACGKVRVLQKTPKGRDIDDKDEFVFN 656
           ***************************************************************************************************** PP
   S: 602  qef 604
           ++f
   Q: 657  EDF 659
           *98 PP

Organism

Aegilops tauschii

Protein Sequence
(Fasta)

MLLADQDELR APNASAPGGG TANLFRKKAT LPQPPATAAT RKPLRIKIGQ PKLPKNFEED 60
TWAILKDAIT AIFLKQKLSC DVEKLYQAAG DLCLHKLGAN LYERVKKECE IHISAKISAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGCTCG CCGACCAGGA CGAGCTCCGC GCTCCCAACG CGTCGGCCCC AGGGGGTGGC 60
ACGGCCAACC TCTTCCGGAA GAAGGCCACG CTCCCGCAGC CTCCTGCCAC CGCCGCCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Interpro

IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0048825--P:cotyledon development
GO:0006281--P:DNA repair
GO:0009908--P:flower development
GO:0009755--P:hormone-mediated signaling pathway
GO:0010100--P:negative regulation of photomorphogenesis
GO:0009640--P:photomorphogenesis
GO:0000209--P:protein polyubiquitination
GO:0048575--P:short-day photoperiodism, flowering
GO:0010182--P:sugar mediated signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ats:F775_31987

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002062	Ailuropoda melanoleuca	57.75	0.00e+00	831.00
IUUC-Atr-002727	Amborella trichopoda	80.11	0.00e+00	1183.00
IUUC-Apl-004157	Anas platyrhynchos	55.78	0.00e+00	833.00
IUUC-Aca-004430	Anolis carolinensis	57.22	0.00e+00	825.00
IUUC-Aly-006547	Arabidopsis lyrata	77.96	0.00e+00	1155.00
IUUC-Ath-006748	Arabidopsis thaliana	77.93	0.00e+00	1149.00
IUUC-Acl-008359	Aspergillus clavatus	35.24	4.00e-121	428.00
IUUC-Afl-008567	Aspergillus flavus	36.25	2.00e-133	469.00
IUUC-Afu-008833	Aspergillus fumigatus	36.15	3.00e-127	448.00
IUUC-Ani-009373	Aspergillus nidulans	36.42	1.00e-135	476.00
IUUC-Ang-009622	Aspergillus niger	38.33	1.00e-137	483.00
IUUC-Aor-010241	Aspergillus oryzae	37.47	9.00e-133	466.00
IUUC-Ate-010251	Aspergillus terreus	38.38	8.00e-140	490.00
IUUC-Ame-010809	Astyanax mexicanus	55.07	0.00e+00	791.00
IUUC-Bgr-012219	Blumeria graminis	34.64	1.00e-111	396.00
IUUC-Bta-013244	Bos taurus	57.75	0.00e+00	828.00
IUUC-Bci-013744	Botrytis cinerea	36.84	2.00e-122	432.00
IUUC-Bdi-014223	Brachypodium distachyon	96.44	0.00e+00	1515.00
IUUC-Bol-015666	Brassica oleracea	77.50	0.00e+00	1207.00
IUUC-Bra-017794	Brassica rapa	78.49	0.00e+00	1186.00
IUUC-Cja-019180	Callithrix jacchus	57.75	0.00e+00	830.00
IUUC-Cfa-021189	Canis familiaris	57.61	0.00e+00	828.00
IUUC-Cpo-021928	Cavia porcellus	57.75	0.00e+00	831.00
IUUC-Cre-022739	Chlamydomonas reinhardtii	51.35	0.00e+00	676.00
IUUC-Csa-023831	Chlorocebus sabaeus	57.75	0.00e+00	830.00
IUUC-Cho-024899	Choloepus hoffmanni	62.18	0.00e+00	649.00
IUUC-Cin-025727	Ciona intestinalis	53.33	0.00e+00	638.00
IUUC-Csv-026117	Ciona savignyi	43.80	0.00e+00	667.00
IUUC-Cgl-026761	Colletotrichum gloeosporioides	37.17	4.00e-124	438.00
IUUC-Cme-027355	Cyanidioschyzon merolae	32.31	9.00e-109	387.00
IUUC-Dre-027916	Danio rerio	54.94	0.00e+00	815.00
IUUC-Dno-028879	Dasypus novemcinctus	53.06	0.00e+00	756.00
IUUC-Dor-030698	Dipodomys ordii	56.20	0.00e+00	783.00
IUUC-Dse-031159	Dothistroma septosporum	33.99	3.00e-115	409.00
IUUC-Dme-031652	Drosophila melanogaster	50.07	0.00e+00	736.00
IUUC-Ete-033101	Echinops telfairi	53.16	0.00e+00	728.00
IUUC-Eca-033952	Equus caballus	57.42	0.00e+00	823.00
IUUC-Eeu-034767	Erinaceus europaeus	57.93	0.00e+00	786.00
IUUC-Fca-036211	Felis catus	55.79	0.00e+00	824.00
IUUC-Fal-037248	Ficedula albicollis	55.91	0.00e+00	832.00
IUUC-Fox-037854	Fusarium oxysporum	36.77	1.00e-117	416.00
IUUC-Fso-038138	Fusarium solani	36.43	2.00e-126	445.00
IUUC-Gmo-038754	Gadus morhua	55.35	0.00e+00	819.00
IUUC-Ggr-040003	Gaeumannomyces graminis	35.43	5.00e-104	371.00
IUUC-Gga-041002	Gallus gallus	56.00	0.00e+00	833.00
IUUC-Gac-041555	Gasterosteus aculeatus	56.60	0.00e+00	811.00
IUUC-Gma-043960	Glycine max	84.18	0.00e+00	1257.00
IUUC-Ggo-045468	Gorilla gorilla	57.00	0.00e+00	778.00
IUUC-Hsa-046848	Homo sapiens	57.75	0.00e+00	831.00
IUUC-Hvu-047510	Hordeum vulgare	99.60	0.00e+00	977.00
IUUC-Itr-048365	Ictidomys tridecemlineatus	57.89	0.00e+00	830.00
IUUC-Lch-049858	Latimeria chalumnae	57.61	0.00e+00	840.00
IUUC-Lpe-051446	Leersia perrieri	93.14	0.00e+00	1452.00
IUUC-Loc-051804	Lepisosteus oculatus	54.21	0.00e+00	798.00
IUUC-Lma-053080	Leptosphaeria maculans	35.01	4.00e-129	454.00
IUUC-Laf-053701	Loxodonta africana	57.52	0.00e+00	828.00
IUUC-Mcc-055538	Macaca mulatta	56.76	0.00e+00	812.00
IUUC-Mor-057102	Magnaporthe oryzae	34.35	3.00e-113	402.00
IUUC-Mpo-057342	Magnaporthe poae	36.35	8.00e-106	377.00
IUUC-Mtr-058660	Medicago truncatula	80.32	0.00e+00	1253.00
IUUC-Mla-058936	Melampsora laricipopulina	37.61	1.00e-107	383.00
IUUC-Mga-059754	Meleagris gallopavo	55.78	0.00e+00	834.00
IUUC-Mvi-060455	Microbotryum violaceum	45.37	6.00e-148	517.00
IUUC-Mmr-060870	Microcebus murinus	57.46	0.00e+00	824.00
IUUC-Mdo-062015	Monodelphis domestica	56.90	0.00e+00	821.00
IUUC-Mmu-063751	Mus musculus	57.61	0.00e+00	830.00
IUUC-Mac-064443	Musa acuminata	83.33	0.00e+00	1318.00
IUUC-Mpu-065903	Mustela putorius furo	57.75	0.00e+00	830.00
IUUC-Mlu-068213	Myotis lucifugus	56.13	0.00e+00	833.00
IUUC-Nfi-068363	Neosartorya fischeri	36.81	6.00e-129	454.00
IUUC-Ncr-068950	Neurospora crassa	35.52	3.00e-117	416.00
IUUC-Nle-069480	Nomascus leucogenys	57.75	0.00e+00	830.00
IUUC-Ont-071562	Oreochromis niloticus	54.70	0.00e+00	797.00
IUUC-Oan-073607	Ornithorhynchus anatinus	56.15	0.00e+00	832.00
IUUC-Ocu-074446	Oryctolagus cuniculus	57.75	0.00e+00	830.00
IUUC-Oba-075198	Oryza barthii	93.93	0.00e+00	1453.00
IUUC-Obr-076095	Oryza brachyantha	93.67	0.00e+00	1454.00
IUUC-Ogl-077032	Oryza glaberrima	94.57	0.00e+00	1445.00
IUUC-Ogu-078051	Oryza glumaepatula	94.06	0.00e+00	1457.00
IUUC-Oin-079399	Oryza indica	94.58	0.00e+00	1152.00
IUUC-Olo-080988	Oryza longistaminata	92.70	0.00e+00	1445.00
IUUC-Ome-081600	Oryza meridionalis	92.70	0.00e+00	1444.00
IUUC-Oni-082623	Oryza nivara	92.83	0.00e+00	1445.00
IUUC-Opu-083762	Oryza punctata	91.86	0.00e+00	1441.00
IUUC-Oru-084499	Oryza rufipogon	94.06	0.00e+00	1453.00
IUUC-Ola-087157	Oryzias latipes	55.36	0.00e+00	812.00
IUUC-Olu-087650	Ostreococcus lucimarinus	52.20	0.00e+00	695.00
IUUC-Oga-088416	Otolemur garnettii	56.58	0.00e+00	801.00
IUUC-Oar-090230	Ovis aries	57.75	0.00e+00	828.00
IUUC-Ptr-091153	Pan troglodytes	57.75	0.00e+00	830.00
IUUC-Pan-091729	Papio anubis	57.75	0.00e+00	830.00
IUUC-Psi-093773	Pelodiscus sinensis	55.67	0.00e+00	827.00
IUUC-Pma-094678	Petromyzon marinus	50.25	3.00e-167	580.00
IUUC-Pno-094946	Phaeosphaeria nodorum	35.23	1.00e-107	383.00
IUUC-Ppa-095688	Physcomitrella patens	74.13	0.00e+00	1160.00
IUUC-Pfo-097037	Poecilia formosa	55.41	0.00e+00	796.00
IUUC-Pab-097622	Pongo abelii	56.20	0.00e+00	800.00
IUUC-Pop-099729	Populus trichocarpa	92.31	2.00e-161	560.00
IUUC-Pca-100391	Procavia capensis	53.55	1.00e-175	608.00
IUUC-Ppe-101142	Prunus persica	81.76	0.00e+00	1245.00
IUUC-Pva-102995	Pteropus vampyrus	61.43	0.00e+00	641.00
IUUC-Pgr-103334	Puccinia graminis	36.26	1.00e-104	374.00
IUUC-Ptt-103903	Puccinia triticina	40.14	4.00e-95	342.00
IUUC-Pte-104167	Pyrenophora teres	34.79	4.00e-129	454.00
IUUC-Pyt-104736	Pyrenophora triticirepentis	35.12	2.00e-129	455.00
IUUC-Rno-106119	Rattus norvegicus	57.46	0.00e+00	828.00
IUUC-Sha-106958	Sarcophilus harrisii	57.32	0.00e+00	828.00
IUUC-Sja-107940	Schizosaccharomyces japonicus	35.22	5.00e-109	387.00
IUUC-Spo-108109	Schizosaccharomyces pombe	34.72	1.00e-103	369.00
IUUC-Ssl-108537	Sclerotinia sclerotiorum	37.07	6.00e-124	437.00
IUUC-Smo-108872	Selaginella moellendorffii	76.01	0.00e+00	1200.00
IUUC-Sit-110626	Setaria italica	91.95	0.00e+00	1434.00
IUUC-Sly-111497	Solanum lycopersicum	80.83	0.00e+00	1261.00
IUUC-Sar-113581	Sorex araneus	49.21	5.00e-167	580.00
IUUC-Sbi-113931	Sorghum bicolor	92.22	0.00e+00	1441.00
IUUC-Sre-114943	Sporisorium reilianum	38.58	3.00e-134	472.00
IUUC-Ssc-116133	Sus scrofa	56.20	0.00e+00	781.00
IUUC-Tgu-116462	Taeniopygia guttata	55.64	0.00e+00	825.00
IUUC-Tru-118299	Takifugu rubripes	55.48	0.00e+00	817.00
IUUC-Tsy-119517	Tarsius syrichta	68.00	6.00e-147	513.00
IUUC-Tni-119798	Tetraodon nigroviridis	54.40	0.00e+00	785.00
IUUC-Tca-121626	Theobroma cacao	79.89	0.00e+00	1253.00
IUUC-Tre-121907	Trichoderma reesei	36.27	2.00e-123	436.00
IUUC-Tvi-122568	Trichoderma virens	35.88	1.00e-122	433.00
IUUC-Tae-124101	Triticum aestivum	99.87	0.00e+00	1524.00
IUUC-Tur-126032	Triticum urartu	99.30	0.00e+00	1448.00
IUUC-Tme-127162	Tuber melanosporum	40.18	9.00e-135	473.00
IUUC-Tbe-127658	Tupaia belangeri	56.46	0.00e+00	795.00
IUUC-Ttr-129112	Tursiops truncatus	53.24	0.00e+00	737.00
IUUC-Uma-129531	Ustilago maydis	36.93	2.00e-115	409.00
IUUC-Vda-129701	Verticillium dahliae	36.68	4.00e-130	458.00
IUUC-Vpa-130217	Vicugna pacos	51.41	0.00e+00	704.00
IUUC-Vvi-131133	Vitis vinifera	82.50	0.00e+00	1265.00
IUUC-Xtr-132761	Xenopus tropicalis	53.47	0.00e+00	803.00
IUUC-Xma-134149	Xiphophorus maculatus	55.54	0.00e+00	822.00
IUUC-Zma-135529	Zea mays	91.42	0.00e+00	1432.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence