iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-057964

Ensembl Protein ID

KEH38235

UniProt Accession

A0A072VJB0; A0A072VJB0_MEDTR

Genbank Protein ID

KEH38235.1

Protein Name

Defective in cullin neddylation protein

Genbank Nucleotide ID

CM001218

Gene Name

MTR_2g064415

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_2g064415	KEH38235	KEH38235

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	2.80e-80	270.3	55	241
UBD/Alpha-Helix/UBA	1.50e-06	29.6	10	46

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkdeqkfkdiYrfaf 102
           ++++leel++rYkd++ d+i ++g++ +c+d++vdp+di++Lvl+w+++a t+cefs++ef +gl++lg+ds+ek++ek++ ++selkdeqkf++iY+faf
   Q: 55   DTRHLEELYNRYKDKYIDMIYADGITLLCNDIQVDPQDIVMLVLSWHMKAGTMCEFSKKEFTEGLQSLGIDSLEKFREKIPYMRSELKDEQKFREIYNFAF 155
           6799************************************************************************************************* PP
   S: 103  nfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWPvliDefveyl 188
            +ak+kgqksl+ldtai +w+Ll+ae++++l+++w++fL+ +++k+is+DtW +lLef+k++++ ls+Yd+egaWP+liDefv+yl
   Q: 156  GWAKEKGQKSLALDTAIGMWQLLFAEKQWPLVEHWCQFLQARHNKAISRDTWSQLLEFAKTVSSNLSDYDAEGAWPYLIDEFVDYL 241
           ***********************************************************************************996 PP

UBD/Alpha-Helix/UBA

   S: 5    dkleqlve.MGFdreealqaLraannnleaAveyLld 40
           dk++q+v  +G +++ a qaL a+++nle A +y+++
   Q: 10   DKVQQFVTiTGASEKVAMQALKASDWNLEGAFDYFYS 46
           89*********************************97 PP

Organism

Medicago truncatula

Functional Description
(View)

Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

Protein Sequence
(Fasta)

MHKLGRGHRD KVQQFVTITG ASEKVAMQAL KASDWNLEGA FDYFYSQPQL RTFTDTRHLE 60
ELYNRYKDKY IDMIYADGIT LLCNDIQVDP QDIVMLVLSW HMKAGTMCEF SKKEFTEGLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTCATTCAA GATTTTGAAA GGTATCCAAA TCCAAATATT TTTAAACCAA AAGAATTGTT 60
TATACTCTTC TTATGCCTGC CTACTCGAAC ATAAGAAGAA ATCGAGGTAA GTAGGGTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

KEGG

mtr:MTR_2g064415

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000561	Aegilops tauschii	72.51	2.00e-115	407.00
IUUC-Aml-001879	Ailuropoda melanoleuca	41.87	2.00e-57	214.00
IUUC-Atr-002697	Amborella trichopoda	88.29	3.00e-57	213.00
IUUC-Apl-003933	Anas platyrhynchos	42.28	2.00e-57	215.00
IUUC-Aca-005269	Anolis carolinensis	40.89	2.00e-56	211.00
IUUC-Aly-006285	Arabidopsis lyrata	66.67	5.00e-94	336.00
IUUC-Ath-007531	Arabidopsis thaliana	74.49	4.00e-112	396.00
IUUC-Ago-007806	Ashbya gossypii	26.09	6.00e-18	83.60
IUUC-Acl-008172	Aspergillus clavatus	27.78	5.00e-25	107.00
IUUC-Afl-008569	Aspergillus flavus	28.69	2.00e-29	121.00
IUUC-Afu-009005	Aspergillus fumigatus	27.65	6.00e-19	86.30
IUUC-Ani-009241	Aspergillus nidulans	22.82	4.00e-19	87.80
IUUC-Ang-009664	Aspergillus niger	28.85	9.00e-27	112.00
IUUC-Aor-009902	Aspergillus oryzae	27.78	7.00e-11	58.90
IUUC-Ate-010414	Aspergillus terreus	27.49	3.00e-28	117.00
IUUC-Ame-011763	Astyanax mexicanus	42.28	2.00e-58	218.00
IUUC-Bgr-011991	Blumeria graminis	29.17	1.00e-18	86.30
IUUC-Bta-013561	Bos taurus	40.95	2.00e-52	197.00
IUUC-Bci-013824	Botrytis cinerea	32.14	1.00e-28	119.00
IUUC-Bdi-014138	Brachypodium distachyon	72.18	5.00e-113	399.00
IUUC-Bol-016110	Brassica oleracea	75.20	1.00e-113	401.00
IUUC-Bra-017111	Brassica rapa	76.02	2.00e-114	404.00
IUUC-Cel-018441	Caenorhabditis elegans	35.27	6.00e-41	160.00
IUUC-Cja-018854	Callithrix jacchus	42.28	6.00e-58	216.00
IUUC-Cfa-020523	Canis familiaris	41.38	5.00e-53	200.00
IUUC-Cpo-022196	Cavia porcellus	41.46	4.00e-57	213.00
IUUC-Cre-022620	Chlamydomonas reinhardtii	43.25	4.00e-60	224.00
IUUC-Csa-023551	Chlorocebus sabaeus	42.11	3.00e-58	217.00
IUUC-Cho-024373	Choloepus hoffmanni	41.46	2.00e-53	201.00
IUUC-Cin-025269	Ciona intestinalis	42.11	5.00e-60	223.00
IUUC-Csv-025976	Ciona savignyi	36.26	1.00e-32	132.00
IUUC-Cgl-026386	Colletotrichum gloeosporioides	31.61	3.00e-21	94.40
IUUC-Cne-026950	Cryptococcus neoformans	33.46	1.00e-33	135.00
IUUC-Cme-027199	Cyanidioschyzon merolae	31.97	1.00e-08	53.50
IUUC-Dre-028247	Danio rerio	42.68	7.00e-59	219.00
IUUC-Dno-028974	Dasypus novemcinctus	42.11	3.00e-58	217.00
IUUC-Dor-030143	Dipodomys ordii	42.68	3.00e-58	218.00
IUUC-Dse-031365	Dothistroma septosporum	27.42	5.00e-25	107.00
IUUC-Dme-032197	Drosophila melanogaster	38.91	3.00e-53	201.00
IUUC-Ete-032371	Echinops telfairi	41.87	2.00e-57	214.00
IUUC-Eca-033242	Equus caballus	41.87	2.00e-57	214.00
IUUC-Eeu-035317	Erinaceus europaeus	41.46	4.00e-57	213.00
IUUC-Fca-036061	Felis catus	41.70	1.00e-57	215.00
IUUC-Fal-036715	Ficedula albicollis	42.28	1.00e-57	215.00
IUUC-Fox-037884	Fusarium oxysporum	30.92	1.00e-15	75.50
IUUC-Fso-038150	Fusarium solani	26.70	1.00e-15	76.60
IUUC-Gmo-038750	Gadus morhua	43.50	2.00e-58	218.00
IUUC-Ggr-039959	Gaeumannomyces graminis	26.79	5.00e-15	75.50
IUUC-Gga-040935	Gallus gallus	42.11	4.00e-58	217.00
IUUC-Gac-041937	Gasterosteus aculeatus	42.28	2.00e-58	218.00
IUUC-Gma-043545	Glycine max	91.89	7.00e-145	505.00
IUUC-Ggo-044972	Gorilla gorilla	42.11	6.00e-58	216.00
IUUC-Hsa-046089	Homo sapiens	42.11	3.00e-58	217.00
IUUC-Hvu-047636	Hordeum vulgare	34.81	4.00e-20	90.50
IUUC-Itr-047902	Ictidomys tridecemlineatus	42.68	3.00e-57	214.00
IUUC-Kpa-049127	Komagataella pastoris	29.08	5.00e-26	110.00
IUUC-Lch-049751	Latimeria chalumnae	42.51	3.00e-58	217.00
IUUC-Lpe-051540	Leersia perrieri	74.09	7.00e-116	409.00
IUUC-Loc-052509	Lepisosteus oculatus	42.51	1.00e-58	219.00
IUUC-Lma-053103	Leptosphaeria maculans	27.78	3.00e-24	105.00
IUUC-Laf-053972	Loxodonta africana	43.50	4.00e-59	220.00
IUUC-Mcc-054700	Macaca mulatta	42.11	5.00e-58	216.00
IUUC-Meu-056791	Macropus eugenii	36.33	1.00e-43	169.00
IUUC-Mor-056909	Magnaporthe oryzae	27.97	1.00e-23	103.00
IUUC-Mpo-057299	Magnaporthe poae	27.14	2.00e-18	85.50
IUUC-Mla-058990	Melampsora laricipopulina	24.00	7.00e-15	73.90
IUUC-Mga-060072	Meleagris gallopavo	42.68	9.00e-58	216.00
IUUC-Mvi-060312	Microbotryum violaceum	34.68	9.00e-41	159.00
IUUC-Mmr-060851	Microcebus murinus	41.87	3.00e-57	214.00
IUUC-Mdo-063074	Monodelphis domestica	41.87	6.00e-57	215.00
IUUC-Mmu-063816	Mus musculus	42.51	5.00e-59	220.00
IUUC-Mac-065016	Musa acuminata	82.97	1.00e-91	327.00
IUUC-Mpu-066870	Mustela putorius furo	41.38	5.00e-53	200.00
IUUC-Mlu-067701	Myotis lucifugus	41.46	2.00e-56	211.00
IUUC-Nfi-068610	Neosartorya fischeri	28.24	6.00e-19	86.30
IUUC-Ncr-068780	Neurospora crassa	24.09	4.00e-18	84.30
IUUC-Nle-069291	Nomascus leucogenys	42.11	3.00e-58	217.00
IUUC-Opr-070682	Ochotona princeps	39.36	2.00e-41	162.00
IUUC-Ont-071813	Oreochromis niloticus	43.09	7.00e-59	219.00
IUUC-Oan-073031	Ornithorhynchus anatinus	41.46	5.00e-57	213.00
IUUC-Ocu-074648	Oryctolagus cuniculus	41.87	2.00e-57	214.00
IUUC-Oba-074993	Oryza barthii	74.19	1.00e-116	411.00
IUUC-Obr-076341	Oryza brachyantha	72.98	7.00e-115	405.00
IUUC-Ogl-077099	Oryza glaberrima	74.19	1.00e-116	411.00
IUUC-Ogu-078285	Oryza glumaepatula	75.00	1.00e-117	414.00
IUUC-Oin-079441	Oryza indica	74.60	3.00e-117	413.00
IUUC-Olo-081037	Oryza longistaminata	74.60	3.00e-117	413.00
IUUC-Ome-081357	Oryza meridionalis	74.60	3.00e-117	413.00
IUUC-Oni-082632	Oryza nivara	74.19	2.00e-116	410.00
IUUC-Opu-083351	Oryza punctata	73.39	2.00e-108	384.00
IUUC-Oru-084306	Oryza rufipogon	74.60	3.00e-117	413.00
IUUC-Osa-085307	Oryza sativa	74.60	3.00e-117	413.00
IUUC-Ola-086868	Oryzias latipes	42.68	3.00e-59	221.00
IUUC-Olu-087646	Ostreococcus lucimarinus	43.50	6.00e-54	203.00
IUUC-Oga-088621	Otolemur garnettii	42.28	2.00e-57	214.00
IUUC-Oar-090405	Ovis aries	41.46	8.00e-57	212.00
IUUC-Ptr-090735	Pan troglodytes	41.87	2.00e-57	214.00
IUUC-Pan-092825	Papio anubis	42.11	3.00e-58	217.00
IUUC-Psi-093110	Pelodiscus sinensis	41.38	1.00e-52	199.00
IUUC-Pma-094196	Petromyzon marinus	37.63	3.00e-41	161.00
IUUC-Pno-095145	Phaeosphaeria nodorum	28.28	2.00e-19	89.00
IUUC-Ppa-095306	Physcomitrella patens	73.17	1.00e-112	398.00
IUUC-Pfo-097121	Poecilia formosa	41.87	2.00e-59	222.00
IUUC-Pab-098197	Pongo abelii	40.95	4.00e-52	197.00
IUUC-Pop-098821	Populus trichocarpa	86.18	5.00e-61	224.00
IUUC-Pca-100218	Procavia capensis	40.24	5.00e-56	210.00
IUUC-Ppe-102032	Prunus persica	85.48	1.00e-130	458.00
IUUC-Pva-102691	Pteropus vampyrus	42.91	5.00e-59	220.00
IUUC-Pgr-103633	Puccinia graminis	27.62	9.00e-20	90.10
IUUC-Ptt-103979	Puccinia triticina	31.94	3.00e-04	38.90
IUUC-Pyt-104428	Pyrenophora triticirepentis	26.89	6.00e-20	90.50
IUUC-Rno-105016	Rattus norvegicus	42.91	4.00e-59	220.00
IUUC-Sce-106358	Saccharomyces cerevisiae	26.62	2.00e-21	95.10
IUUC-Sha-106542	Sarcophilus harrisii	42.11	2.00e-57	215.00
IUUC-Sja-107938	Schizosaccharomyces japonicus	28.63	2.00e-21	95.10
IUUC-Spo-108207	Schizosaccharomyces pombe	33.84	1.00e-24	105.00
IUUC-Ssl-108410	Sclerotinia sclerotiorum	31.37	3.00e-29	121.00
IUUC-Smo-108750	Selaginella moellendorffii	65.98	7.00e-96	342.00
IUUC-Sit-110052	Setaria italica	76.10	9.00e-119	418.00
IUUC-Sly-111489	Solanum lycopersicum	81.32	3.00e-126	443.00
IUUC-Stu-112517	Solanum tuberosum	63.41	2.00e-97	347.00
IUUC-Sar-113509	Sorex araneus	42.44	4.00e-38	150.00
IUUC-Sbi-114113	Sorghum bicolor	74.70	6.00e-116	409.00
IUUC-Sre-115221	Sporisorium reilianum	24.74	2.00e-22	98.60
IUUC-Ssc-115547	Sus scrofa	42.11	3.00e-58	217.00
IUUC-Tgu-117196	Taeniopygia guttata	42.28	1.00e-57	215.00
IUUC-Tru-117740	Takifugu rubripes	42.45	1.00e-58	218.00
IUUC-Tsy-119599	Tarsius syrichta	41.87	2.00e-57	214.00
IUUC-Tni-120542	Tetraodon nigroviridis	43.15	2.00e-57	214.00
IUUC-Tca-121033	Theobroma cacao	85.71	8.00e-136	475.00
IUUC-Tre-121986	Trichoderma reesei	23.83	6.00e-19	87.40
IUUC-Tvi-122607	Trichoderma virens	28.79	2.00e-24	105.00
IUUC-Tae-125740	Triticum aestivum	62.33	8.00e-110	389.00
IUUC-Tur-126375	Triticum urartu	56.92	5.00e-104	370.00
IUUC-Tme-126878	Tuber melanosporum	31.89	7.00e-34	137.00
IUUC-Tbe-127429	Tupaia belangeri	39.36	2.00e-41	162.00
IUUC-Ttr-129086	Tursiops truncatus	38.62	2.00e-49	188.00
IUUC-Uma-129364	Ustilago maydis	26.37	9.00e-28	116.00
IUUC-Vda-129929	Verticillium dahliae	30.85	9.00e-19	87.40
IUUC-Vpa-130048	Vicugna pacos	36.18	1.00e-43	169.00
IUUC-Vvi-130834	Vitis vinifera	84.17	1.00e-133	468.00
IUUC-Xtr-131888	Xenopus tropicalis	41.06	2.00e-57	214.00
IUUC-Xma-134122	Xiphophorus maculatus	42.28	2.00e-60	224.00
IUUC-Yli-134595	Yarrowia lipolytica	29.96	7.00e-31	126.00
IUUC-Zma-135642	Zea mays	73.90	7.00e-115	405.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence