iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025699

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

EAAA01001041

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000016625.2	ENSCINT00000013154.3	ENSCINP00000013154.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-23	81.8	385	418
E3 activity/RING/U-box	1.60e-06	27.9	5	54
UBD/Beta-Prp	4.80e-43	147.2	221	425

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrt 32
           gH+++vt+++f  ++ +l++++dD ++k+WDlr+
   Q: 385  GHSGPVTAISFseNGYYLATAADDASVKLWDLRK 418
           8**********976699**************986 PP

E3 activity/RING/U-box

   S: 10   IslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnl 59
           +s+e+++ P+++p sG +++++ +ek++ + g+ +Pv ++pl+ e++v  +
   Q: 5    VSGEVPEVPCISPvSGCVFEKRLLEKFVFEHGT-DPVSNEPLSMEQVVEMK 54
           799*************************99998.**********9998765 PP

UBD/Beta-Prp

   S: 15   cvkf.spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
           c++  s d++ ++tg++d+t  v+d ++++++ +l+gh+++vt v ++p +++  t+s D ti++w++++g+c ++++ h++ v+ +s+
   Q: 221  CLDLcSSDTNRVITGGADKTAVVFDKENEQVITTLKGHTKKVTHVLYHPVEDVVFTSSPDSTIRIWSVQNGDCSSIIRTHKEAVTGISL 309
           44445999********************************************************************************* PP
   S: 103  spsgdklvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfds 190
           ++ gd+l+s s+d+     d++tgq l   t++  +++ +c+++hpdg ++ +G+ D+++++Wdlk  + +  + g h ++v+ +sf++
   Q: 310  HALGDYLLSCSEDQHWAFSDVRTGQTLCRvTDDAISSALTCAQFHPDGLIFGTGTVDSQIKIWDLKERTNVANFPG-HSGPVTAISFSE 397
           *************************99888*********************************************9.************ PP
   S: 191  ngkelvsgsldgtvklwdlqtgecvrtl 218
           ng +l+++++d +vklwdl++ +  +tl
   Q: 398  NGYYLATAADDASVKLWDLRKLKNFKTL 425
           *******************976655554 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

FVKLVSGEVP EVPCISPVSG CVFEKRLLEK FVFEHGTDPV SNEPLSMEQV VEMKTNPLVK 60
PKPPSATSIP AILKSLQDEW DACMLTSFTL RQQLHTTRQE LSHALYQHDA ACRVIARLTK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTGTTAAAT TAGTTTCCGG TGAAGTTCCT GAAGTGCCAT GTATATCCCC AGTCTCAGGT 60
TGTGTCTTCG AGAAACGTTT GTTGGAGAAA TTTGTTTTTG AGCACGGTAC GGACCCCGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013915--Pre-mRNA_splic_Prp19
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08606--Prp19
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0000974--C:Prp19 complex
GO:0071006--C:U2-type catalytic step 1 spliceosome
GO:0004842--F:ubiquitin-protein transferase activity
GO:0000349--P:generation of catalytic spliceosome for first transesterification step

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000488	Aegilops tauschii	42.54	3.00e-92	332.00
IUUC-Aml-001230	Ailuropoda melanoleuca	67.27	7.00e-174	602.00
IUUC-Atr-002594	Amborella trichopoda	44.64	9.00e-107	379.00
IUUC-Apl-003686	Anas platyrhynchos	62.06	3.00e-138	483.00
IUUC-Aca-005272	Anolis carolinensis	68.58	3.00e-179	619.00
IUUC-Aly-005586	Arabidopsis lyrata	45.56	2.00e-109	388.00
IUUC-Ath-007693	Arabidopsis thaliana	45.01	8.00e-107	379.00
IUUC-Ago-007879	Ashbya gossypii	26.90	3.00e-29	121.00
IUUC-Acl-008335	Aspergillus clavatus	38.26	2.00e-67	248.00
IUUC-Afl-008527	Aspergillus flavus	38.46	6.00e-72	263.00
IUUC-Afu-008957	Aspergillus fumigatus	38.21	1.00e-74	272.00
IUUC-Ani-009280	Aspergillus nidulans	39.62	3.00e-65	241.00
IUUC-Ang-009746	Aspergillus niger	38.15	5.00e-69	253.00
IUUC-Aor-009905	Aspergillus oryzae	38.23	4.00e-75	273.00
IUUC-Ate-010412	Aspergillus terreus	38.46	1.00e-66	245.00
IUUC-Ame-011561	Astyanax mexicanus	63.82	4.00e-80	289.00
IUUC-Bgr-012283	Blumeria graminis	33.49	1.00e-51	196.00
IUUC-Bta-013242	Bos taurus	68.12	2.00e-180	623.00
IUUC-Bci-013901	Botrytis cinerea	37.26	1.00e-65	242.00
IUUC-Bdi-014277	Brachypodium distachyon	46.49	5.00e-110	389.00
IUUC-Bol-016457	Brassica oleracea	46.12	5.00e-110	390.00
IUUC-Bra-017650	Brassica rapa	45.68	1.00e-109	388.00
IUUC-Cel-018271	Caenorhabditis elegans	50.93	5.00e-126	442.00
IUUC-Cja-019879	Callithrix jacchus	68.26	2.00e-179	620.00
IUUC-Cfa-020175	Canis familiaris	67.89	1.00e-179	621.00
IUUC-Cpo-022379	Cavia porcellus	68.12	4.00e-180	622.00
IUUC-Cre-022993	Chlamydomonas reinhardtii	43.79	3.00e-91	327.00
IUUC-Csa-023500	Chlorocebus sabaeus	68.35	0.00e+00	625.00
IUUC-Cho-025065	Choloepus hoffmanni	56.72	7.00e-93	332.00
IUUC-Csv-026128	Ciona savignyi	85.43	0.00e+00	740.00
IUUC-Cgl-026507	Colletotrichum gloeosporioides	35.39	6.00e-61	226.00
IUUC-Cne-026860	Cryptococcus neoformans	39.95	6.00e-84	303.00
IUUC-Dre-028187	Danio rerio	67.28	1.00e-175	608.00
IUUC-Dno-029453	Dasypus novemcinctus	68.35	0.00e+00	625.00
IUUC-Dor-030150	Dipodomys ordii	65.55	5.00e-85	306.00
IUUC-Dse-031220	Dothistroma septosporum	34.42	6.00e-59	220.00
IUUC-Dme-031906	Drosophila melanogaster	63.62	8.00e-156	541.00
IUUC-Ete-033035	Echinops telfairi	72.29	3.00e-75	274.00
IUUC-Eca-033478	Equus caballus	68.12	4.00e-180	622.00
IUUC-Eeu-034974	Erinaceus europaeus	70.04	3.00e-119	420.00
IUUC-Fca-036194	Felis catus	68.12	5.00e-180	622.00
IUUC-Fal-037417	Ficedula albicollis	68.12	3.00e-179	619.00
IUUC-Fox-037922	Fusarium oxysporum	35.15	7.00e-62	229.00
IUUC-Fso-038256	Fusarium solani	36.14	1.00e-64	238.00
IUUC-Gmo-038713	Gadus morhua	68.88	1.00e-179	621.00
IUUC-Ggr-039854	Gaeumannomyces graminis	34.20	5.00e-51	194.00
IUUC-Gga-041143	Gallus gallus	68.12	2.00e-179	620.00
IUUC-Gac-042129	Gasterosteus aculeatus	68.71	4.00e-179	619.00
IUUC-Gma-043635	Glycine max	45.35	7.00e-108	382.00
IUUC-Ggo-045262	Gorilla gorilla	68.35	0.00e+00	625.00
IUUC-Hsa-046036	Homo sapiens	68.35	0.00e+00	625.00
IUUC-Hvu-047442	Hordeum vulgare	43.75	4.00e-67	246.00
IUUC-Itr-048169	Ictidomys tridecemlineatus	68.35	6.00e-178	615.00
IUUC-Lch-050105	Latimeria chalumnae	68.81	2.00e-177	614.00
IUUC-Lpe-050976	Leersia perrieri	46.91	7.00e-109	386.00
IUUC-Loc-052042	Lepisosteus oculatus	60.40	7.00e-123	432.00
IUUC-Lma-053143	Leptosphaeria maculans	36.26	1.00e-62	233.00
IUUC-Laf-053451	Loxodonta africana	65.34	9.00e-177	611.00
IUUC-Mcc-055786	Macaca mulatta	68.35	0.00e+00	625.00
IUUC-Meu-056161	Macropus eugenii	68.51	4.00e-101	360.00
IUUC-Mor-057215	Magnaporthe oryzae	34.93	2.00e-55	208.00
IUUC-Mpo-057419	Magnaporthe poae	32.00	2.00e-48	185.00
IUUC-Mtr-057756	Medicago truncatula	46.99	1.00e-107	382.00
IUUC-Mla-059085	Melampsora laricipopulina	38.26	5.00e-77	280.00
IUUC-Mga-060158	Meleagris gallopavo	66.21	9.00e-169	585.00
IUUC-Mvi-060441	Microbotryum violaceum	37.98	2.00e-62	231.00
IUUC-Mmr-061085	Microcebus murinus	68.35	0.00e+00	625.00
IUUC-Mdo-061804	Monodelphis domestica	68.35	1.00e-180	624.00
IUUC-Mmu-063608	Mus musculus	65.27	3.00e-176	610.00
IUUC-Mac-064972	Musa acuminata	46.45	2.00e-105	374.00
IUUC-Mpu-065700	Mustela putorius furo	67.89	8.00e-180	621.00
IUUC-Mlu-068223	Myotis lucifugus	64.75	1.00e-174	604.00
IUUC-Nfi-068504	Neosartorya fischeri	36.88	5.00e-74	270.00
IUUC-Ncr-068729	Neurospora crassa	36.43	2.00e-59	221.00
IUUC-Nle-069754	Nomascus leucogenys	68.35	0.00e+00	625.00
IUUC-Opr-070621	Ochotona princeps	68.51	3.00e-180	623.00
IUUC-Ont-071377	Oreochromis niloticus	67.80	5.00e-178	615.00
IUUC-Oan-073498	Ornithorhynchus anatinus	47.55	2.00e-79	287.00
IUUC-Ocu-074182	Oryctolagus cuniculus	65.21	5.00e-177	612.00
IUUC-Oba-075509	Oryza barthii	45.74	2.00e-108	384.00
IUUC-Obr-076480	Oryza brachyantha	46.29	2.00e-109	388.00
IUUC-Ogl-077052	Oryza glaberrima	45.74	2.00e-108	385.00
IUUC-Ogu-078919	Oryza glumaepatula	45.74	1.00e-108	385.00
IUUC-Oin-079357	Oryza indica	44.70	5.00e-102	363.00
IUUC-Olo-080376	Oryza longistaminata	45.83	2.00e-98	351.00
IUUC-Ome-081973	Oryza meridionalis	45.56	2.00e-98	351.00
IUUC-Oni-082849	Oryza nivara	45.74	8.00e-109	385.00
IUUC-Opu-083243	Oryza punctata	45.84	1.00e-108	385.00
IUUC-Oru-084613	Oryza rufipogon	45.74	4.00e-108	384.00
IUUC-Osa-085407	Oryza sativa	45.74	2.00e-108	384.00
IUUC-Ola-086566	Oryzias latipes	67.12	1.00e-175	608.00
IUUC-Olu-087757	Ostreococcus lucimarinus	40.62	4.00e-87	313.00
IUUC-Oga-089010	Otolemur garnettii	67.81	1.00e-174	604.00
IUUC-Oar-089638	Ovis aries	68.12	2.00e-180	623.00
IUUC-Ptr-091141	Pan troglodytes	68.35	0.00e+00	625.00
IUUC-Pan-092662	Papio anubis	68.35	0.00e+00	625.00
IUUC-Psi-093777	Pelodiscus sinensis	68.35	4.00e-144	502.00
IUUC-Pno-095115	Phaeosphaeria nodorum	37.09	5.00e-64	237.00
IUUC-Ppa-095841	Physcomitrella patens	45.68	2.00e-109	388.00
IUUC-Pfo-096390	Poecilia formosa	67.35	3.00e-176	609.00
IUUC-Pab-098250	Pongo abelii	68.35	4.00e-180	622.00
IUUC-Pop-099854	Populus trichocarpa	46.59	6.00e-111	393.00
IUUC-Pca-100553	Procavia capensis	67.89	5.00e-178	615.00
IUUC-Ppe-101383	Prunus persica	45.64	2.00e-102	365.00
IUUC-Pva-102189	Pteropus vampyrus	67.89	5.00e-180	622.00
IUUC-Pgr-103304	Puccinia graminis	35.89	4.00e-72	264.00
IUUC-Ptt-103984	Puccinia triticina	36.11	5.00e-77	280.00
IUUC-Pte-104385	Pyrenophora teres	36.21	2.00e-68	251.00
IUUC-Pyt-104697	Pyrenophora triticirepentis	36.26	1.00e-68	251.00
IUUC-Rno-105581	Rattus norvegicus	68.12	6.00e-180	622.00
IUUC-Sce-106147	Saccharomyces cerevisiae	44.80	1.00e-23	103.00
IUUC-Sha-107071	Sarcophilus harrisii	65.28	3.00e-177	613.00
IUUC-Sja-107697	Schizosaccharomyces japonicus	28.57	8.00e-36	143.00
IUUC-Spo-108315	Schizosaccharomyces pombe	31.89	5.00e-42	164.00
IUUC-Ssl-108628	Sclerotinia sclerotiorum	36.97	2.00e-66	244.00
IUUC-Smo-109648	Selaginella moellendorffii	44.72	2.00e-105	374.00
IUUC-Sit-109873	Setaria italica	46.45	4.00e-108	384.00
IUUC-Sly-111673	Solanum lycopersicum	46.58	2.00e-101	361.00
IUUC-Stu-112125	Solanum tuberosum	46.22	1.00e-100	358.00
IUUC-Sbi-114696	Sorghum bicolor	44.59	1.00e-97	348.00
IUUC-Sre-115134	Sporisorium reilianum	34.05	2.00e-72	265.00
IUUC-Ssc-116260	Sus scrofa	68.12	2.00e-180	624.00
IUUC-Tgu-116533	Taeniopygia guttata	68.35	9.00e-180	621.00
IUUC-Tru-117800	Takifugu rubripes	67.80	2.00e-177	613.00
IUUC-Tsy-118980	Tarsius syrichta	64.14	2.00e-165	574.00
IUUC-Tni-120334	Tetraodon nigroviridis	69.45	2.00e-120	424.00
IUUC-Tca-121807	Theobroma cacao	46.12	1.00e-108	385.00
IUUC-Tre-121920	Trichoderma reesei	36.06	1.00e-61	229.00
IUUC-Tvi-122294	Trichoderma virens	33.73	5.00e-51	194.00
IUUC-Tae-125794	Triticum aestivum	46.85	6.00e-110	389.00
IUUC-Tur-126664	Triticum urartu	41.94	7.00e-102	363.00
IUUC-Tme-127026	Tuber melanosporum	37.15	4.00e-71	260.00
IUUC-Tbe-127582	Tupaia belangeri	70.41	2.00e-119	421.00
IUUC-Ttr-128313	Tursiops truncatus	67.89	2.00e-178	617.00
IUUC-Uma-129626	Ustilago maydis	34.12	1.00e-70	259.00
IUUC-Vda-129699	Verticillium dahliae	34.91	2.00e-62	231.00
IUUC-Vpa-130593	Vicugna pacos	67.59	2.00e-178	617.00
IUUC-Vvi-131668	Vitis vinifera	45.68	2.00e-108	384.00
IUUC-Xtr-132186	Xenopus tropicalis	67.59	8.00e-175	604.00
IUUC-Xma-133212	Xiphophorus maculatus	67.35	3.00e-176	609.00
IUUC-Yli-134607	Yarrowia lipolytica	53.12	2.00e-36	143.00
IUUC-Zma-135662	Zea mays	46.12	7.00e-109	386.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence