iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003255

Ensembl Protein ID

ENSAPLP00000009982.1

UniProt Accession

U3IRV9; U3IRV9_ANAPL

Genbank Protein ID

ENSAPLP00000009982

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01009883

Gene Name

CDC20

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000010237.1	ENSAPLT00000010684.1	ENSAPLP00000009982.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.70e-27	92.4	262	297
E3 adaptor/Cullin RING/APC_C/CDC20	1.40e-143	477.4	127	435

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gHt +v++l++  d ++l+sG++D+ + +W  ++g+
   Q: 262  GHTQEVCGLKWsLDgRYLASGGNDNLVNIWPATQGD 297
           8***********666***************988775 PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+++ldape+r+d+ylnL+dWss+n lavaL++svylw+ ++g++++l ++ +++d+v+svsw++eg++lavGt+++ev+++D++++k+
   Q: 127  PDRILDAPEIRNDYYLNLIDWSSQNFLAVALDNSVYLWNCTSGEIIHLLQMeHPDDYVSSVSWVKEGNYLAVGTSNAEVQLWDIQQQKR 215
           689************************************************8899********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse.....Pl 172
           +r++ +hs+rvg+LsWn++++ssG r g+i+h+dvrv+e++++tl++h+qevCGlkw+ d+++LasGGnDn v++w a++ +     P+
   Q: 216  LRNMVSHSSRVGSLSWNNYIISSGARTGHIHHHDVRVAEHHVATLSGHTQEVCGLKWSLDGRYLASGGNDNLVNIWPATQGDsgdyaPV 304
           *****************************************************************************9998889999** PP
   S: 173  kkfkehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskva 261
           ++f++h++avka+aw+Pwq+++La+GGGt+Dr+i++wn+++g++l+++d++sqvcs+lws ++ke++s+hGf +n++++wkyp+++kv+
   Q: 305  QTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGTCLSAVDAHSQVCSILWSTNYKEFISGHGFVQNQLVIWKYPTMTKVT 393
           ***************************************************************************************** PP
   S: 262  elkgheaRvlslalspdgeaivtaagDetlrfwklfdkkkak 303
           el+gh+aRvl+l++spd++++++aa+Detlrfw++f++++ k
   Q: 394  ELRGHTARVLNLTMSPDSSTVASAAADETLRFWRCFEMDPIK 435
           *************************************98765 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

NTERSIPLRQ CVCVNAGKSG SKIQSTPTKA GGDRYIPNRS TMQMDMANFL LTKENDPAED 60
SPTKKEQQKA WAVNLNGFDV EEAKILRLSG KPQNAPEGYQ NNLKVLYSQK TTPTSSRKNG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATACAGAGC GTTCAATACC TCTAAGACAA TGTGTGTGTG TGAACGCAGG TAAATCTGGA 60
TCCAAAATCC AGAGCACTCC AACAAAAGCT GGGGGGGACC GTTACATTCC CAACCGCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033187--CDC20
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0007064--P:mitotic sister chromatid cohesion
GO:0090307--P:mitotic spindle assembly
GO:0090129--P:positive regulation of synapse maturation
GO:0031915--P:positive regulation of synaptic plasticity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0040020--P:regulation of meiotic nuclear division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000974	Aegilops tauschii	45.66	6.00e-110	390.00
IUUC-Aml-001545	Ailuropoda melanoleuca	80.73	0.00e+00	712.00
IUUC-Atr-003103	Amborella trichopoda	46.45	1.00e-109	389.00
IUUC-Aca-004920	Anolis carolinensis	82.64	0.00e+00	745.00
IUUC-Aly-006253	Arabidopsis lyrata	47.45	1.00e-110	392.00
IUUC-Ath-006795	Arabidopsis thaliana	47.11	1.00e-111	396.00
IUUC-Ate-010479	Aspergillus terreus	46.84	1.00e-90	326.00
IUUC-Bgr-012059	Blumeria graminis	45.80	2.00e-94	339.00
IUUC-Bta-012625	Bos taurus	79.77	0.00e+00	712.00
IUUC-Bci-013607	Botrytis cinerea	48.13	2.00e-96	346.00
IUUC-Bdi-014344	Brachypodium distachyon	47.65	6.00e-110	390.00
IUUC-Bol-015368	Brassica oleracea	46.54	1.00e-108	387.00
IUUC-Bra-016738	Brassica rapa	47.33	7.00e-108	384.00
IUUC-Cja-019132	Callithrix jacchus	80.68	0.00e+00	719.00
IUUC-Cfa-020780	Canis familiaris	79.55	0.00e+00	708.00
IUUC-Cpo-022223	Cavia porcellus	80.45	0.00e+00	674.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	50.48	3.00e-115	408.00
IUUC-Csa-023666	Chlorocebus sabaeus	80.45	0.00e+00	717.00
IUUC-Cho-024920	Choloepus hoffmanni	79.28	4.00e-104	371.00
IUUC-Cin-025675	Ciona intestinalis	54.07	2.00e-121	429.00
IUUC-Csv-026019	Ciona savignyi	54.33	1.00e-115	409.00
IUUC-Cgl-026465	Colletotrichum gloeosporioides	39.51	7.00e-94	337.00
IUUC-Cme-027234	Cyanidioschyzon merolae	50.00	6.00e-103	367.00
IUUC-Dre-028026	Danio rerio	60.26	2.00e-167	582.00
IUUC-Dno-028865	Dasypus novemcinctus	80.27	0.00e+00	706.00
IUUC-Dor-030958	Dipodomys ordii	80.68	0.00e+00	714.00
IUUC-Dse-031391	Dothistroma septosporum	47.85	9.00e-98	350.00
IUUC-Dme-031905	Drosophila melanogaster	52.36	6.00e-134	470.00
IUUC-Ete-032387	Echinops telfairi	75.23	0.00e+00	680.00
IUUC-Eca-033522	Equus caballus	72.95	0.00e+00	634.00
IUUC-Eeu-035059	Erinaceus europaeus	72.31	2.00e-180	625.00
IUUC-Fca-036346	Felis catus	80.63	0.00e+00	634.00
IUUC-Fal-037558	Ficedula albicollis	91.45	0.00e+00	805.00
IUUC-Fox-037850	Fusarium oxysporum	45.98	3.00e-95	342.00
IUUC-Fso-038375	Fusarium solani	40.48	1.00e-96	346.00
IUUC-Gmo-039284	Gadus morhua	64.16	3.00e-174	604.00
IUUC-Ggr-039864	Gaeumannomyces graminis	45.33	1.00e-95	343.00
IUUC-Gga-040790	Gallus gallus	92.26	0.00e+00	827.00
IUUC-Gac-041431	Gasterosteus aculeatus	61.42	1.00e-161	562.00
IUUC-Gma-043489	Glycine max	48.18	1.00e-109	389.00
IUUC-Ggo-045052	Gorilla gorilla	80.23	0.00e+00	717.00
IUUC-Hsa-046305	Homo sapiens	80.23	0.00e+00	717.00
IUUC-Hvu-047476	Hordeum vulgare	46.39	6.00e-109	387.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	80.68	0.00e+00	676.00
IUUC-Lch-050174	Latimeria chalumnae	63.82	3.00e-160	558.00
IUUC-Lpe-050954	Leersia perrieri	47.68	6.00e-102	363.00
IUUC-Loc-052638	Lepisosteus oculatus	64.46	2.00e-165	574.00
IUUC-Lma-052998	Leptosphaeria maculans	41.34	1.00e-99	356.00
IUUC-Laf-053742	Loxodonta africana	80.45	0.00e+00	714.00
IUUC-Mcc-054948	Macaca mulatta	80.45	0.00e+00	717.00
IUUC-Meu-056013	Macropus eugenii	78.38	6.00e-103	367.00
IUUC-Mor-057277	Magnaporthe oryzae	50.00	5.00e-93	335.00
IUUC-Mpo-057624	Magnaporthe poae	49.68	1.00e-93	337.00
IUUC-Mtr-057725	Medicago truncatula	46.64	2.00e-103	369.00
IUUC-Mga-060102	Meleagris gallopavo	92.48	0.00e+00	826.00
IUUC-Mmr-061615	Microcebus murinus	81.13	0.00e+00	710.00
IUUC-Mdo-061982	Monodelphis domestica	80.69	5.00e-177	615.00
IUUC-Mmu-063864	Mus musculus	80.45	0.00e+00	716.00
IUUC-Mac-064861	Musa acuminata	48.06	2.00e-108	385.00
IUUC-Mpu-066502	Mustela putorius furo	80.75	0.00e+00	717.00
IUUC-Mlu-067277	Myotis lucifugus	77.60	0.00e+00	705.00
IUUC-Ncr-068951	Neurospora crassa	45.12	2.00e-93	336.00
IUUC-Nle-070149	Nomascus leucogenys	80.23	0.00e+00	711.00
IUUC-Opr-070778	Ochotona princeps	79.33	4.00e-137	481.00
IUUC-Ont-071660	Oreochromis niloticus	65.82	2.00e-170	591.00
IUUC-Oan-073677	Ornithorhynchus anatinus	80.38	8.00e-177	612.00
IUUC-Ocu-073797	Oryctolagus cuniculus	80.68	0.00e+00	717.00
IUUC-Oba-075514	Oryza barthii	48.17	2.00e-102	365.00
IUUC-Obr-076018	Oryza brachyantha	48.54	1.00e-109	389.00
IUUC-Ogl-077254	Oryza glaberrima	48.17	2.00e-102	365.00
IUUC-Ogu-078521	Oryza glumaepatula	49.14	6.00e-109	388.00
IUUC-Oin-080094	Oryza indica	48.17	2.00e-102	365.00
IUUC-Olo-080449	Oryza longistaminata	47.52	2.00e-102	365.00
IUUC-Ome-081186	Oryza meridionalis	48.78	5.00e-109	389.00
IUUC-Oni-082243	Oryza nivara	48.17	2.00e-102	365.00
IUUC-Opu-084007	Oryza punctata	47.68	1.00e-101	362.00
IUUC-Oru-084562	Oryza rufipogon	49.14	6.00e-109	388.00
IUUC-Osa-086094	Oryza sativa	48.17	3.00e-102	365.00
IUUC-Ola-086907	Oryzias latipes	63.93	5.00e-156	543.00
IUUC-Olu-087647	Ostreococcus lucimarinus	48.30	5.00e-119	420.00
IUUC-Oga-088184	Otolemur garnettii	79.59	0.00e+00	704.00
IUUC-Oar-090023	Ovis aries	79.34	0.00e+00	675.00
IUUC-Ptr-090935	Pan troglodytes	79.77	0.00e+00	710.00
IUUC-Pan-091845	Papio anubis	80.45	0.00e+00	717.00
IUUC-Psi-093188	Pelodiscus sinensis	89.29	0.00e+00	816.00
IUUC-Pma-094187	Petromyzon marinus	52.35	3.00e-130	457.00
IUUC-Pno-094809	Phaeosphaeria nodorum	40.66	2.00e-101	362.00
IUUC-Ppa-095457	Physcomitrella patens	47.12	2.00e-109	389.00
IUUC-Pfo-097429	Poecilia formosa	59.72	8.00e-150	523.00
IUUC-Pab-098603	Pongo abelii	80.45	0.00e+00	717.00
IUUC-Pop-098890	Populus trichocarpa	46.45	1.00e-104	373.00
IUUC-Pca-101062	Procavia capensis	79.91	0.00e+00	703.00
IUUC-Ppe-101865	Prunus persica	47.52	9.00e-100	356.00
IUUC-Pva-102925	Pteropus vampyrus	80.00	0.00e+00	733.00
IUUC-Pte-104142	Pyrenophora teres	41.08	5.00e-99	354.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	40.65	1.00e-98	353.00
IUUC-Rno-106005	Rattus norvegicus	80.23	0.00e+00	712.00
IUUC-Sha-107472	Sarcophilus harrisii	80.00	0.00e+00	721.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	42.32	3.00e-92	332.00
IUUC-Spo-108075	Schizosaccharomyces pombe	43.05	9.00e-97	347.00
IUUC-Ssl-108507	Sclerotinia sclerotiorum	47.55	3.00e-95	342.00
IUUC-Smo-108922	Selaginella moellendorffii	46.37	4.00e-119	421.00
IUUC-Sit-110732	Setaria italica	47.73	7.00e-108	383.00
IUUC-Sly-111202	Solanum lycopersicum	47.10	4.00e-108	384.00
IUUC-Stu-112024	Solanum tuberosum	46.74	6.00e-110	390.00
IUUC-Sar-113092	Sorex araneus	76.82	0.00e+00	658.00
IUUC-Sbi-114558	Sorghum bicolor	47.37	2.00e-109	389.00
IUUC-Ssc-115710	Sus scrofa	80.68	0.00e+00	716.00
IUUC-Tgu-117100	Taeniopygia guttata	90.30	0.00e+00	803.00
IUUC-Tru-118184	Takifugu rubripes	57.68	4.00e-141	493.00
IUUC-Tsy-118892	Tarsius syrichta	79.28	1.00e-105	375.00
IUUC-Tni-120474	Tetraodon nigroviridis	63.97	2.00e-160	558.00
IUUC-Tca-120949	Theobroma cacao	46.35	9.00e-110	389.00
IUUC-Tre-122211	Trichoderma reesei	38.67	1.00e-93	336.00
IUUC-Tvi-122531	Trichoderma virens	38.90	1.00e-94	340.00
IUUC-Tae-123765	Triticum aestivum	45.66	4.00e-110	391.00
IUUC-Tur-126018	Triticum urartu	47.02	3.00e-103	368.00
IUUC-Tme-126905	Tuber melanosporum	48.28	9.00e-96	343.00
IUUC-Tbe-127384	Tupaia belangeri	83.56	6.00e-154	536.00
IUUC-Ttr-128511	Tursiops truncatus	80.27	0.00e+00	709.00
IUUC-Vda-129993	Verticillium dahliae	46.26	4.00e-95	341.00
IUUC-Vpa-130775	Vicugna pacos	47.02	4.00e-80	291.00
IUUC-Vvi-131245	Vitis vinifera	48.53	1.00e-98	352.00
IUUC-Xtr-131993	Xenopus tropicalis	82.15	0.00e+00	760.00
IUUC-Xma-133332	Xiphophorus maculatus	64.72	4.00e-167	580.00
IUUC-Yli-134501	Yarrowia lipolytica	43.33	4.00e-101	361.00
IUUC-Zma-135135	Zea mays	46.84	2.00e-106	379.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence