iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022223

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02053651

Gene Name

CDC20

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000006090.3	ENSCPOT00000006154.2	ENSCPOP00000005494.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.80e-28	95.7	307	336
E3 adaptor/Cullin RING/APC_C/CDC20	6.50e-148	491.9	172	478

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+ +v++l++ +d ++l+sG++D+ + vW
   Q: 307  GHSQEVCGLRWaPDgRHLASGGNDNLVNVW 336
           8***********999*************** PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+++ldape+r+d+ylnL+dWss nvlavaL++svylwsa++gd+ +l ++ +++d+v+sv+wi+eg++lavGt+++ev+++Dv+++k+
   Q: 172  PDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMeQPGDYVSSVAWIKEGNYLAVGTSSAEVQLWDVQQQKR 260
           689************************************************899*********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse....Plk 173
           +r++t+hsarv++LsWn+++lssGsr+g+i+h+dvrv++++++tl++h+qevCGl+w+ d+++LasGGnDn v+vw +s  e    Pl+
   Q: 261  LRNMTSHSARVSSLSWNSYILSSGSRSGHIHHHDVRVADHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSSPGEggwvPLQ 349
           ********************************************************************************9999***** PP
   S: 174  kfkehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvae 262
           +f++h++avka+aw+Pwq+++La+GGGt+Dr+i++wn+++ga+l+++d++sqvcs+lws+++kel+s+hGfa+n++++wkyp+++kvae
   Q: 350  TFTQHQGAVKAVAWCPWQSNILATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAE 438
           ***************************************************************************************** PP
   S: 263  lkgheaRvlslalspdgeaivtaagDetlrfwklfdkkka 302
           lkgh+aRvl+l++spdg+++++aa+Detlr+w++f+ ++a
   Q: 439  LKGHTARVLNLTMSPDGATVASAAADETLRLWRCFELDPA 478
           ***********************************99876 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MAQFVFESDL HSLLQLDAPI PNAPIARWQR KAKEAPGPGP SPMRAANRSH SAGRTPGRTP 60
GKSNSKVQTT PSKPGGDRYI PHRSASQMEV ASFLLSKENQ PENSQTPTKK EHQKAWALNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCAGT TCGTGTTTGA GAGTGACCTG CATTCCCTCC TTCAGCTGGA TGCGCCCATC 60
CCCAATGCAC CCATCGCGCG CTGGCAGCGC AAAGCCAAGG AGGCTCCGGG GCCAGGACCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033187--CDC20
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0007064--P:mitotic sister chromatid cohesion
GO:0090307--P:mitotic spindle assembly
GO:0090129--P:positive regulation of synapse maturation
GO:0031915--P:positive regulation of synaptic plasticity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0040020--P:regulation of meiotic nuclear division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000974	Aegilops tauschii	46.88	5.00e-110	391.00
IUUC-Aml-001545	Ailuropoda melanoleuca	96.99	0.00e+00	941.00
IUUC-Atr-003103	Amborella trichopoda	46.21	2.00e-108	385.00
IUUC-Apl-003255	Anas platyrhynchos	80.45	0.00e+00	753.00
IUUC-Aca-004920	Anolis carolinensis	75.44	0.00e+00	769.00
IUUC-Aly-006012	Arabidopsis lyrata	48.34	7.00e-109	387.00
IUUC-Ath-006795	Arabidopsis thaliana	45.33	2.00e-107	382.00
IUUC-Ate-010479	Aspergillus terreus	50.16	4.00e-91	328.00
IUUC-Ame-010850	Astyanax mexicanus	60.35	9.00e-91	326.00
IUUC-Bgr-012059	Blumeria graminis	49.19	3.00e-94	339.00
IUUC-Bta-012625	Bos taurus	96.39	0.00e+00	940.00
IUUC-Bci-013607	Botrytis cinerea	47.66	1.00e-97	350.00
IUUC-Bdi-014344	Brachypodium distachyon	48.06	3.00e-109	388.00
IUUC-Bol-015368	Brassica oleracea	45.88	1.00e-105	378.00
IUUC-Bra-016738	Brassica rapa	46.36	2.00e-105	376.00
IUUC-Cja-019132	Callithrix jacchus	96.39	0.00e+00	943.00
IUUC-Cfa-020780	Canis familiaris	96.39	0.00e+00	937.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	50.23	2.00e-117	416.00
IUUC-Csa-023666	Chlorocebus sabaeus	97.39	0.00e+00	946.00
IUUC-Cho-024920	Choloepus hoffmanni	96.10	2.00e-158	552.00
IUUC-Cin-025675	Ciona intestinalis	51.59	4.00e-136	478.00
IUUC-Csv-026019	Ciona savignyi	51.32	2.00e-131	462.00
IUUC-Cgl-026465	Colletotrichum gloeosporioides	40.56	4.00e-96	345.00
IUUC-Cme-027234	Cyanidioschyzon merolae	52.46	4.00e-106	378.00
IUUC-Dre-028026	Danio rerio	60.36	0.00e+00	634.00
IUUC-Dno-028865	Dasypus novemcinctus	95.80	0.00e+00	926.00
IUUC-Dor-030958	Dipodomys ordii	96.79	0.00e+00	947.00
IUUC-Dse-031391	Dothistroma septosporum	38.93	2.00e-96	346.00
IUUC-Dme-031905	Drosophila melanogaster	48.50	2.00e-141	495.00
IUUC-Ete-032387	Echinops telfairi	90.78	0.00e+00	892.00
IUUC-Eca-033522	Equus caballus	87.37	0.00e+00	843.00
IUUC-Eeu-035059	Erinaceus europaeus	84.20	0.00e+00	788.00
IUUC-Fca-036346	Felis catus	96.83	0.00e+00	858.00
IUUC-Fal-037558	Ficedula albicollis	79.76	0.00e+00	793.00
IUUC-Fox-037850	Fusarium oxysporum	44.91	3.00e-97	348.00
IUUC-Fso-038375	Fusarium solani	44.82	8.00e-98	350.00
IUUC-Gmo-039284	Gadus morhua	62.30	0.00e+00	631.00
IUUC-Ggr-039864	Gaeumannomyces graminis	48.55	4.00e-99	355.00
IUUC-Gga-040790	Gallus gallus	80.16	0.00e+00	811.00
IUUC-Gac-041431	Gasterosteus aculeatus	62.43	3.00e-180	624.00
IUUC-Gma-043489	Glycine max	46.99	9.00e-106	377.00
IUUC-Ggo-045052	Gorilla gorilla	97.19	0.00e+00	946.00
IUUC-Hsa-046305	Homo sapiens	97.19	0.00e+00	946.00
IUUC-Hvu-047476	Hordeum vulgare	45.58	7.00e-110	390.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	98.60	0.00e+00	909.00
IUUC-Lch-050174	Latimeria chalumnae	62.57	1.00e-173	602.00
IUUC-Lpe-050954	Leersia perrieri	47.56	3.00e-100	358.00
IUUC-Loc-052638	Lepisosteus oculatus	63.12	0.00e+00	632.00
IUUC-Lma-052998	Leptosphaeria maculans	43.27	3.00e-100	359.00
IUUC-Laf-053742	Loxodonta africana	96.59	0.00e+00	936.00
IUUC-Mcc-054948	Macaca mulatta	97.39	0.00e+00	946.00
IUUC-Meu-056013	Macropus eugenii	87.28	6.00e-143	500.00
IUUC-Mor-057277	Magnaporthe oryzae	45.93	1.00e-96	347.00
IUUC-Mpo-057624	Magnaporthe poae	51.47	4.00e-97	348.00
IUUC-Mtr-057725	Medicago truncatula	45.82	2.00e-99	355.00
IUUC-Mga-060102	Meleagris gallopavo	80.20	0.00e+00	811.00
IUUC-Mmr-061615	Microcebus murinus	97.29	0.00e+00	940.00
IUUC-Mdo-061982	Monodelphis domestica	88.89	0.00e+00	775.00
IUUC-Mmu-063864	Mus musculus	95.19	0.00e+00	936.00
IUUC-Mac-064861	Musa acuminata	47.70	6.00e-110	390.00
IUUC-Mpu-066502	Mustela putorius furo	96.99	0.00e+00	933.00
IUUC-Mlu-067277	Myotis lucifugus	89.42	0.00e+00	877.00
IUUC-Ncr-068951	Neurospora crassa	45.33	2.00e-94	340.00
IUUC-Nle-070149	Nomascus leucogenys	97.19	0.00e+00	939.00
IUUC-Opr-070778	Ochotona princeps	95.54	0.00e+00	684.00
IUUC-Ont-071660	Oreochromis niloticus	60.64	2.00e-177	615.00
IUUC-Oan-073677	Ornithorhynchus anatinus	76.89	0.00e+00	701.00
IUUC-Ocu-073797	Oryctolagus cuniculus	97.38	0.00e+00	941.00
IUUC-Oba-075946	Oryza barthii	47.93	2.00e-107	382.00
IUUC-Obr-076018	Oryza brachyantha	46.15	1.00e-107	383.00
IUUC-Ogl-077254	Oryza glaberrima	47.56	2.00e-100	358.00
IUUC-Ogu-078521	Oryza glumaepatula	48.16	1.00e-107	384.00
IUUC-Oin-079145	Oryza indica	47.93	2.00e-107	382.00
IUUC-Olo-080798	Oryza longistaminata	47.91	2.00e-107	383.00
IUUC-Ome-081186	Oryza meridionalis	47.91	2.00e-107	384.00
IUUC-Oni-082243	Oryza nivara	47.56	2.00e-100	358.00
IUUC-Opu-084007	Oryza punctata	47.56	3.00e-100	358.00
IUUC-Oru-084562	Oryza rufipogon	48.16	2.00e-107	383.00
IUUC-Osa-086094	Oryza sativa	47.56	2.00e-100	358.00
IUUC-Ola-086907	Oryzias latipes	60.63	5.00e-165	573.00
IUUC-Olu-087647	Ostreococcus lucimarinus	48.84	5.00e-119	421.00
IUUC-Oga-088184	Otolemur garnettii	95.80	0.00e+00	928.00
IUUC-Oar-090023	Ovis aries	91.09	0.00e+00	835.00
IUUC-Ptr-090935	Pan troglodytes	96.41	0.00e+00	882.00
IUUC-Pan-091845	Papio anubis	97.39	0.00e+00	946.00
IUUC-Psi-093188	Pelodiscus sinensis	80.93	0.00e+00	845.00
IUUC-Pma-094187	Petromyzon marinus	54.56	1.00e-148	519.00
IUUC-Pno-094809	Phaeosphaeria nodorum	40.90	3.00e-101	362.00
IUUC-Ppa-095457	Physcomitrella patens	46.99	2.00e-110	392.00
IUUC-Pfo-097429	Poecilia formosa	59.16	4.00e-161	560.00
IUUC-Pab-098603	Pongo abelii	97.39	0.00e+00	946.00
IUUC-Pop-099654	Populus trichocarpa	46.39	2.00e-102	365.00
IUUC-Pca-101062	Procavia capensis	95.59	0.00e+00	914.00
IUUC-Ppe-101865	Prunus persica	46.76	2.00e-96	345.00
IUUC-Pva-102925	Pteropus vampyrus	95.79	0.00e+00	961.00
IUUC-Pte-104142	Pyrenophora teres	42.42	1.00e-98	353.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	42.26	2.00e-98	353.00
IUUC-Rno-106005	Rattus norvegicus	95.79	0.00e+00	938.00
IUUC-Sha-107472	Sarcophilus harrisii	89.60	0.00e+00	891.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	42.82	2.00e-93	335.00
IUUC-Spo-108075	Schizosaccharomyces pombe	44.72	4.00e-96	345.00
IUUC-Ssl-108507	Sclerotinia sclerotiorum	48.97	4.00e-97	348.00
IUUC-Smo-108922	Selaginella moellendorffii	48.60	5.00e-122	431.00
IUUC-Sit-110732	Setaria italica	46.34	3.00e-108	385.00
IUUC-Sly-111202	Solanum lycopersicum	44.65	2.00e-105	375.00
IUUC-Stu-112676	Solanum tuberosum	45.32	9.00e-97	347.00
IUUC-Sar-113092	Sorex araneus	91.78	0.00e+00	879.00
IUUC-Sbi-114558	Sorghum bicolor	45.58	1.00e-108	386.00
IUUC-Ssc-115710	Sus scrofa	97.80	0.00e+00	949.00
IUUC-Tgu-117100	Taeniopygia guttata	78.97	0.00e+00	793.00
IUUC-Tru-118184	Takifugu rubripes	57.81	4.00e-139	487.00
IUUC-Tsy-118892	Tarsius syrichta	96.81	3.00e-161	560.00
IUUC-Tni-120474	Tetraodon nigroviridis	59.64	3.00e-168	584.00
IUUC-Tca-120949	Theobroma cacao	46.51	4.00e-106	378.00
IUUC-Tre-122211	Trichoderma reesei	40.72	5.00e-97	347.00
IUUC-Tvi-122531	Trichoderma virens	40.75	5.00e-98	351.00
IUUC-Tae-123765	Triticum aestivum	46.88	4.00e-110	391.00
IUUC-Tur-126018	Triticum urartu	45.90	8.00e-103	367.00
IUUC-Tbe-127384	Tupaia belangeri	98.32	2.00e-176	611.00
IUUC-Ttr-128511	Tursiops truncatus	96.39	0.00e+00	934.00
IUUC-Vda-129993	Verticillium dahliae	40.39	3.00e-97	349.00
IUUC-Vvi-131245	Vitis vinifera	46.70	9.00e-94	337.00
IUUC-Xtr-131993	Xenopus tropicalis	73.10	0.00e+00	754.00
IUUC-Xma-133332	Xiphophorus maculatus	62.33	4.00e-178	617.00
IUUC-Zma-135135	Zea mays	47.94	2.00e-107	382.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence