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Tag Content
UUCD2 ID IUUC-Laf-053502
UUCD1 version UUC-LoA-00393
Ensembl Protein ID ENSLAFP00000009624.4
UniProt Accession G3T7M9; G3T7M9_LOXAF
Protein Name Uncharacterized protein
Gene Name DDB1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSLAFG00000011513.4 ENSLAFT00000011520.4 ENSLAFP00000009624.4
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DDB1 0 1816.5 1 1140
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DDB1
   S: 2    mldrYvvtarkpsavvklvvgnftshkelNLliaksnrieiflvtpeglrpvvevklegsiavlrlfrpknekkdllfilteryntl 88
           m+++Yvvta+kp+av+ +v+g+fts+++lNLliak++r+ei++vt+eglrpv+ev ++g+iav++lfrpk+e+kdllfilt++yn++
   Q: 1    MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNAC 87
           799************************************************************************************ PP
   S: 89   ilelrdidessevvtradgevlDdigrssdsGlinviepkirlialelyqglfklIvldndikelkafnirleelnvsdvkflillt 175
           ile+++++es++++tra+g+v+D+igr+s++G+i++i+p++r+i+l+ly+glfk+I+ld+d+kelkafnirleel+v+dvkfl++++
   Q: 88   ILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQ 174
           *************************************************************************************** PP
   S: 176  qptgrvlviyqdddgkhlktyelslkdKeFvkis.kqesiekeaellipvpsqlvgvlvlgeesivyksadnykdvdPylirqstai 261
           +pt  ++++yqd++g+h+ktye+sl++KeF+k++ kqe++e+ea+++i+vp++++g++++g+esi+y+++d+y +++P++i+qst++
   Q: 175  APT--ICFVYQDPQGRHVKTYEVSLREKEFNKGPwKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIV 259
           ***..********************************************************************************** PP
   S: 262  ryervdnngirylLgdfdGelkllllsaeeemsG.vevkslkielLgeisiaesisyldngllfvgsrfgdsQlvklisestgkgsy 347
           +++rvd ng+rylLgd++G+l++lll++ee+m+G v +k+l++elLge+siae+++yldng++fvgsr+gdsQlvkl+++s+++gsy
   Q: 260  CHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGtVSLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSY 346
           *************************************************************************************** PP
   S: 348  vvilerfknlkpIvdlvvvdldrrgqgqvvtvsgaskdGslRvirlgigieelasvdlkgvigllslkstidestdnslvlafvset 434
           vv++e+f+nl+pIvd++vvdl+r+gqgq+vt+sga+k+GslR+ir+gigi+e+as+dl+g++gl++l+s+ +++td++lvl+fv++t
   Q: 347  VVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQT 433
           *************************************************************************************** PP
   S: 435  kvlnlntgeeledtelsgvlsdlqtlltqdvidykqllqvTsqsvrLvssqikrllkeWkaknleiigvassNteqvliaatsndlv 521
           +vl+ln gee+e+tel+g+++d+qt+++ +v + +ql+q+Ts+svrLvs++ k+l++eWk++++++++vas+N++qv++a+ +++l+
   Q: 434  RVLMLN-GEEVEETELMGFVDDQQTFFCGNV-AQQQLIQITSASVRLVSQEPKALVSEWKEPQGKNVSVASCNSSQVVVAV-GRALY 517
           ******.************************.9999********************************************9.***** PP
   S: 522  yleigdgeldltstttlenevavldlinieddpnlsdleavglltdiskrililpdletiykeklggeiipRsilltefEnvtYlLi 608
           yl+i+++el+++s+t++e+eva+ld+++++d++ ls l+a+gl+tdis+ril+lp++e+++ke+lggeiipRsil+t+fE+ +YlL+
   Q: 518  YLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLC 604
           *************************************************************************************** PP
   S: 609  algdGalvsyildidtgdesdakksnlgtspgtlktfkslsttqvfassDrPtvIyssskkLvfSnVnlkeVqylCsldseaypdsl 695
           algdGal+++ l+i+tg +sd+kk++lgt+p++l+tf+slstt+vfa+sDrPtvIyss++kLvfSnVnlkeV+y+C+l+s++ypdsl
   Q: 605  ALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSL 691
           *************************************************************************************** PP
   S: 696  alanngslvigtvddiqklkiRsiplgeslrriayqesvitfgvisdrreldf.klklkalrnnasilalvpdiennklfsdglril 781
           alann++l+igt+d+iqkl+iR++pl+es+r+i+yqe++++fgv+s+r+e+++ +++++alr++as++al+++++++klfs++++ +
   Q: 692  ALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDtSGGTTALRPSASTQALSSSVSSSKLFSSSTAPH 778
           *****************************************************9********************************* PP
   S: 782  elseleenevnfllvlDkntfelllaqdlrewEtavsllSqklkdDseeyyvvktalvlpeenelkkgrilvfsvedslklkLltva 868
           e+s++ee+ev++ll++D++tfe+l+a+++ ++E+a+sl+S+kl++D+++y++v+ta+v+pee+e+k+gri+vf+++d+   kL+tva
   Q: 779  ETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDG---KLQTVA 862
           ******************************************************************************...****** PP
   S: 869  ekkvkgavidlvklNgkllaainseirlyewkvmgtdekelrkeCernntilaLtlktrkdfivVgDlmrsvtLllykdlegsfeEs 955
           ek+vkgav+++v++Ngklla+ins++rlyew    t+ekelr+eC+++n+i+aL+lkt++dfi+VgDlmrsv Ll+yk +eg+feE+
   Q: 863  EKEVKGAVYSMVEFNGKLLASINSTVRLYEW----TTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEI 945
           *******************************....**************************************************** PP
   S: 956  ardynlewmsaveilnddiflgaencgNlfvvkkdikagltdeerslleevgefrlgefvevfrfgtlvlqdvgerevnrssevifg 1042
           ard+n++wmsaveil+dd+flgaen++Nlfv++kd +a++tdeer++l+evg f+lgefv+vf++g+lv+q++ge++++++++v+fg
   Q: 946  ARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKD-SAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFG 1031
           ***********************************.*************************************************** PP
   S: 1043 tengeigvilrlrrellkflrnlestlkkvikrvakieHssyRsFetekrterasgfvdgdLiesilDlsrdkavdilkvl.yekrw 1128
           t+ng+ig++++l+++++++l +++++l+kvik+v+kieHs++RsF+te++te+a+gf+dgdLies+lD+sr+k+++++++l y++++
   Q: 1032 TVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPAT
Organism Loxodonta africana
Protein Sequence
(Fasta)
MSYNYVVTAQ KPTAVNGCVT GHFTSAEDLN LLIAKNTRLE IYVVTAEGLR PVKEVGMYGK 60
IAVMELFRPK GESKDLLFIL TAKYNACILE YKQSGESIDI ITRAHGNVQD RIGRPSETGI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Laf-053502|E3,DDB1|Loxodonta africana
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTCGTACA ACTACGTGGT AACGGCACAG AAGCCCACTG CCGTGAACGG CTGCGTGACC 60
GGTACGGCTG CCAGGGCCGG AGACCCCGGC GAGGGAGGGG GCTGGGGGAG CCGAGGCCCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Laf-053502|E3,DDB1|Loxodonta africana
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR004871--Cleavage/polyA-sp_fac_asu_C
IPR031297--DDB1
IPR015943--WD40/YVTN_repeat-like_dom
IPR017986--WD40_repeat_dom
Pfam

PF03178--CPSF_A
Gene Ontology

GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0031465--C:Cul4B-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0000784--C:nuclear chromosome, telomeric region
GO:0005654--C:nucleoplasm
GO:0003684--F:damaged DNA binding
GO:0035518--P:histone H2A monoubiquitination
GO:0051702--P:interaction with symbiont
GO:0043066--P:negative regulation of apoptotic process
GO:0046726--P:positive regulation by virus of viral protein levels in host cell
GO:0045070--P:positive regulation of viral genome replication
GO:1902188--P:positive regulation of viral release from host cell
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:1901990--P:regulation of mitotic cell cycle phase transition
GO:0070914--P:UV-damage excision repair
GO:0016055--P:Wnt signaling pathway
KEGG lav:100659188
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000120 Aegilops tauschii 50.13 0.00e+00 1135.00
IUUC-Aml-002096 Ailuropoda melanoleuca 99.74 0.00e+00 2306.00
IUUC-Atr-002742 Amborella trichopoda 52.44 0.00e+00 1181.00
IUUC-Apl-003624 Anas platyrhynchos 96.27 0.00e+00 2184.00
IUUC-Aca-005085 Anolis carolinensis 96.93 0.00e+00 2244.00
IUUC-Aly-005857 Arabidopsis lyrata 52.79 0.00e+00 1186.00
IUUC-Ath-006658 Arabidopsis thaliana 52.71 0.00e+00 1182.00
IUUC-Acl-008149 Aspergillus clavatus 26.80 2.00e-105 377.00
IUUC-Afl-008549 Aspergillus flavus 27.93 1.00e-109 391.00
IUUC-Afu-009076 Aspergillus fumigatus 26.89 4.00e-116 412.00
IUUC-Ani-009302 Aspergillus nidulans 26.49 1.00e-89 325.00
IUUC-Ang-009636 Aspergillus niger 27.51 3.00e-83 303.00
IUUC-Aor-010073 Aspergillus oryzae 27.98 3.00e-114 406.00
IUUC-Ate-010422 Aspergillus terreus 26.73 2.00e-105 377.00
IUUC-Ame-011643 Astyanax mexicanus 81.01 0.00e+00 1838.00
IUUC-Bgr-012164 Blumeria graminis 26.14 2.00e-97 350.00
IUUC-Bta-012494 Bos taurus 99.56 0.00e+00 2305.00
IUUC-Bci-013957 Botrytis cinerea 26.05 5.00e-91 329.00
IUUC-Bdi-014186 Brachypodium distachyon 52.88 0.00e+00 1181.00
IUUC-Bol-015922 Brassica oleracea 53.23 0.00e+00 1197.00
IUUC-Bra-017300 Brassica rapa 53.23 0.00e+00 1190.00
IUUC-Cel-018239 Caenorhabditis elegans 37.08 0.00e+00 773.00
IUUC-Cja-019165 Callithrix jacchus 99.65 0.00e+00 2305.00
IUUC-Cfa-020406 Canis familiaris 99.74 0.00e+00 2306.00
IUUC-Cpo-022154 Cavia porcellus 98.95 0.00e+00 2289.00
IUUC-Cre-022557 Chlamydomonas reinhardtii 40.86 0.00e+00 784.00
IUUC-Csa-024061 Chlorocebus sabaeus 99.65 0.00e+00 2305.00
IUUC-Cho-024554 Choloepus hoffmanni 92.80 0.00e+00 942.00
IUUC-Cin-025466 Ciona intestinalis 61.63 0.00e+00 1469.00
IUUC-Csv-026370 Ciona savignyi 60.09 0.00e+00 1305.00
IUUC-Cgl-026595 Colletotrichum gloeosporioides 25.68 7.00e-97 349.00
IUUC-Cme-027342 Cyanidioschyzon merolae 27.39 4.00e-114 406.00
IUUC-Dre-027448 Danio rerio 91.73 0.00e+00 1028.00
IUUC-Dno-029794 Dasypus novemcinctus 99.07 0.00e+00 2159.00
IUUC-Dor-030789 Dipodomys ordii 85.39 0.00e+00 986.00
IUUC-Dse-031491 Dothistroma septosporum 27.88 6.00e-116 412.00
IUUC-Dme-031940 Drosophila melanogaster 60.66 0.00e+00 1367.00
IUUC-Ete-032913 Echinops telfairi 80.54 0.00e+00 857.00
IUUC-Eca-033777 Equus caballus 98.86 0.00e+00 2279.00
IUUC-Eeu-034900 Erinaceus europaeus 97.47 0.00e+00 1125.00
IUUC-Fca-035869 Felis catus 99.74 0.00e+00 2306.00
IUUC-Fal-036777 Ficedula albicollis 96.68 0.00e+00 2229.00
IUUC-Fox-037954 Fusarium oxysporum 26.52 1.00e-104 374.00
IUUC-Fso-038292 Fusarium solani 25.65 1.00e-108 388.00
IUUC-Gmo-038815 Gadus morhua 82.33 0.00e+00 970.00
IUUC-Ggr-039907 Gaeumannomyces graminis 25.45 9.00e-97 348.00
IUUC-Gga-040995 Gallus gallus 96.93 0.00e+00 2244.00
IUUC-Gac-042390 Gasterosteus aculeatus 90.47 0.00e+00 2001.00
IUUC-Gma-042904 Glycine max 52.14 0.00e+00 1138.00
IUUC-Ggo-044891 Gorilla gorilla 99.30 0.00e+00 2296.00
IUUC-Hsa-046709 Homo sapiens 99.65 0.00e+00 2305.00
IUUC-Hvu-047504 Hordeum vulgare 52.36 0.00e+00 1162.00
IUUC-Itr-048678 Ictidomys tridecemlineatus 99.65 0.00e+00 2306.00
IUUC-Lch-050565 Latimeria chalumnae 93.35 0.00e+00 2174.00
IUUC-Lpe-051260 Leersia perrieri 53.10 0.00e+00 1179.00
IUUC-Loc-052091 Lepisosteus oculatus 82.16 0.00e+00 1478.00
IUUC-Lma-053246 Leptosphaeria maculans 25.47 3.00e-103 370.00
IUUC-Mcc-054802 Macaca mulatta 99.65 0.00e+00 2289.00
IUUC-Meu-056808 Macropus eugenii 95.77 0.00e+00 1448.00
IUUC-Mor-057253 Magnaporthe oryzae 25.48 3.00e-84 306.00
IUUC-Mpo-057562 Magnaporthe poae 25.04 4.00e-95 343.00
IUUC-Mtr-057743 Medicago truncatula 51.53 0.00e+00 1156.00
IUUC-Mla-059154 Melampsora laricipopulina 24.32 9.00e-80 292.00
IUUC-Mga-059824 Meleagris gallopavo 96.18 0.00e+00 2091.00
IUUC-Mvi-060279 Microbotryum violaceum 26.81 8.00e-110 392.00
IUUC-Mmr-061215 Microcebus murinus 99.04 0.00e+00 2284.00
IUUC-Mdo-062028 Monodelphis domestica 96.60 0.00e+00 1879.00
IUUC-Mmu-064327 Mus musculus 99.47 0.00e+00 2301.00
IUUC-Mac-065445 Musa acuminata 53.10 0.00e+00 1156.00
IUUC-Mpu-065814 Mustela putorius furo 96.40 0.00e+00 2204.00
IUUC-Mlu-067136 Myotis lucifugus 99.12 0.00e+00 2289.00
IUUC-Nfi-068355 Neosartorya fischeri 26.89 2.00e-109 390.00
IUUC-Ncr-068620 Neurospora crassa 25.10 1.00e-90 328.00
IUUC-Nle-069566 Nomascus leucogenys 99.47 0.00e+00 2275.00
IUUC-Opr-070915 Ochotona princeps 90.79 0.00e+00 1868.00
IUUC-Ont-071753 Oreochromis niloticus 91.32 0.00e+00 2120.00
IUUC-Oan-073187 Ornithorhynchus anatinus 97.87 0.00e+00 2052.00
IUUC-Ocu-074619 Oryctolagus cuniculus 99.65 0.00e+00 2303.00
IUUC-Oba-075091 Oryza barthii 45.83 0.00e+00 894.00
IUUC-Obr-076425 Oryza brachyantha 53.91 0.00e+00 1182.00
IUUC-Ogu-078794 Oryza glumaepatula 53.36 0.00e+00 1186.00
IUUC-Oin-079725 Oryza indica 53.45 0.00e+00 1175.00
IUUC-Olo-080842 Oryza longistaminata 52.13 0.00e+00 1084.00
IUUC-Ome-081818 Oryza meridionalis 53.45 0.00e+00 1189.00
IUUC-Oni-082879 Oryza nivara 52.66 0.00e+00 1162.00
IUUC-Opu-083361 Oryza punctata 52.67 0.00e+00 1177.00
IUUC-Oru-084781 Oryza rufipogon 53.36 0.00e+00 1187.00
IUUC-Osa-086293 Oryza sativa 53.36 0.00e+00 1187.00
IUUC-Ola-086881 Oryzias latipes 89.95 0.00e+00 2086.00
IUUC-Olu-087674 Ostreococcus lucimarinus 45.19 0.00e+00 956.00
IUUC-Oga-089056 Otolemur garnettii 99.47 0.00e+00 2303.00
IUUC-Oar-089457 Ovis aries 99.55 0.00e+00 2270.00
IUUC-Ptr-091179 Pan troglodytes 99.47 0.00e+00 2263.00
IUUC-Pan-092019 Papio anubis 99.13 0.00e+00 2291.00
IUUC-Psi-093407 Pelodiscus sinensis 96.80 0.00e+00 2204.00
IUUC-Pma-094272 Petromyzon marinus 86.64 0.00e+00 1845.00
IUUC-Pno-094864 Phaeosphaeria nodorum 26.88 1.00e-112 401.00
IUUC-Ppa-095885 Physcomitrella patens 53.04 0.00e+00 1165.00
IUUC-Pfo-096083 Poecilia formosa 90.71 0.00e+00 2101.00
IUUC-Pab-098652 Pongo abelii 94.68 0.00e+00 2152.00
IUUC-Pop-099593 Populus trichocarpa 52.66 0.00e+00 1132.00
IUUC-Pca-100189 Procavia capensis 99.40 0.00e+00 1330.00
IUUC-Ppe-101987 Prunus persica 52.14 0.00e+00 1115.00
IUUC-Pva-102605 Pteropus vampyrus 99.56 0.00e+00 2301.00
IUUC-Pgr-103659 Puccinia graminis 24.29 3.00e-73 270.00
IUUC-Ptt-103884 Puccinia triticina 22.88 2.00e-57 218.00
IUUC-Pte-104233 Pyrenophora teres 27.07 2.00e-116 414.00
IUUC-Pyt-104454 Pyrenophora triticirepentis 27.15 2.00e-114 407.00
IUUC-Rno-106004 Rattus norvegicus 99.56 0.00e+00 2302.00
IUUC-Sha-106726 Sarcophilus harrisii 96.54 0.00e+00 2079.00
IUUC-Sja-107864 Schizosaccharomyces japonicus 23.40 8.00e-75 275.00
IUUC-Spo-108029 Schizosaccharomyces pombe 26.02 4.00e-101 362.00
IUUC-Ssl-108441 Sclerotinia sclerotiorum 25.28 1.00e-83 305.00
IUUC-Smo-108808 Selaginella moellendorffii 52.36 0.00e+00 1209.00
IUUC-Sit-109735 Setaria italica 53.91 0.00e+00 1178.00
IUUC-Sly-111520 Solanum lycopersicum 52.13 0.00e+00 1151.00
IUUC-Sar-113606 Sorex araneus 96.27 2.00e-137 483.00
IUUC-Sbi-114539 Sorghum bicolor 52.90 0.00e+00 1165.00
IUUC-Sre-114936 Sporisorium reilianum 24.78 2.00e-64 241.00
IUUC-Ssc-116038 Sus scrofa 99.56 0.00e+00 2303.00
IUUC-Tgu-117512 Taeniopygia guttata 96.84 0.00e+00 2236.00
IUUC-Tru-117593 Takifugu rubripes 89.66 0.00e+00 2082.00
IUUC-Tsy-119513 Tarsius syrichta 96.21 0.00e+00 1204.00
IUUC-Tni-120551 Tetraodon nigroviridis 84.83 0.00e+00 1700.00
IUUC-Tca-121505 Theobroma cacao 53.10 0.00e+00 1156.00
IUUC-Tre-122136 Trichoderma reesei 26.13 2.00e-103 370.00
IUUC-Tvi-122512 Trichoderma virens 25.12 1.00e-99 358.00
IUUC-Tae-122891 Triticum aestivum 52.27 0.00e+00 1162.00
IUUC-Tur-126451 Triticum urartu 52.77 0.00e+00 1057.00
IUUC-Tme-127057 Tuber melanosporum 28.82 9.00e-113 401.00
IUUC-Ttr-128891 Tursiops truncatus 94.65 0.00e+00 1484.00
IUUC-Uma-129583 Ustilago maydis 25.34 3.00e-55 211.00
IUUC-Vda-129870 Verticillium dahliae 25.10 5.00e-92 332.00
IUUC-Vpa-130117 Vicugna pacos 94.91 0.00e+00 1741.00
IUUC-Vvi-131033 Vitis vinifera 51.97 0.00e+00 1157.00
IUUC-Xtr-131987 Xenopus tropicalis 93.18 0.00e+00 2139.00
IUUC-Xma-134117 Xiphophorus maculatus 88.72 0.00e+00 2050.00
IUUC-Zma-134758 Zea mays 53.19 0.00e+00 1182.00
Created Date 25-Jun-2017

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