iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093407

Ensembl Protein ID

ENSPSIP00000015016.1

UniProt Accession

K7G405; K7G405_PELSI

Genbank Protein ID

ENSPSIP00000015016

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01001011

Gene Name

DDB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000013275.1	ENSPSIT00000015087.1	ENSPSIP00000015016.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DDB1	0	1759.2	2	1124

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DDB1

   S: 21   vgnftshkelNLliaksnrieiflvtpeglrpvvevklegsiavlrlfrpknekkdllfilteryntlilelrdidessevvtradg 107
            g+fts+++lNLliak++r+ei++vtpeglrpv+ev ++g+iav++lf+pk+e+kdllfilt++yn++ile+++++es++++tra+g
   Q: 2    AGHFTSAEDLNLLIAKNTRLEIYVVTPEGLRPVKEVGMYGKIAVMELFHPKGENKDLLFILTAKYNACILEYKQSGESIDIITRAHG 88
           59************************************************************************************* PP
   S: 108  evlDdigrssdsGlinviepkirlialelyqglfklIvldndikelkafnirleelnvsdvkflilltqptgrvlviyqdddgkhlk 194
           +v+D+igr+s++G+i++i+p++r+i+l+ly+glfk+I+l++d+kelkafnirleel+v+dvkfl+++++pt  ++++yqd++g+h+k
   Q: 89   NVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLERDNKELKAFNIRLEELQVIDVKFLYGCQAPT--ICFVYQDPQGRHVK 173
           ***********************************************************************..************** PP
   S: 195  tyelslkdKeFvkis.kqesiekeaellipvpsqlvgvlvlgeesivyksadnykdvdPylirqstairyervdnngirylLgdfdG 280
           tye+sl++KeF+k++ kqe++e+ea+++i+vp++++g++++g+esi+y+++d+y +++P++i+qst+++++rvd ng+rylLgd++G
   Q: 174  TYEVSLREKEFNKGPwKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEG 260
           *************************************************************************************** PP
   S: 281  elkllllsaeeemsG.vevkslkielLgeisiaesisyldngllfvgsrfgdsQlvklisestgkgsyvvilerfknlkpIvdlvvv 366
           +l++lll++ee+m+G v++k+l++elLge+siae+++yldng++fvgsr+gdsQlvkl ++s+++gsyvv++e+f+nl+pIvd++vv
   Q: 261  RLFMLLLEKEEQMDGtVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLSVDSNEQGSYVVAMETFTNLGPIVDMCVV 347
           *************************************************************************************** PP
   S: 367  dldrrgqgqvvtvsgaskdGslRvirlgigieelasvdlkgvigllslkstidestdnslvlafvsetkvlnlntgeeledtelsgv 453
           dl+r+gqgq+vt+sga+k+GslR+ir+gigi+e+as+dl+g++gl++l+s++ ++tdn+lvl+fv++t+vl+ln gee+e+tel+g+
   Q: 348  DLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDSHRETDNTLVLSFVGQTRVLMLN-GEEVEETELTGF 433
           **************************************************************************.************ PP
   S: 454  lsdlqtlltqdvidykqllqvTsqsvrLvssqikrllkeWkaknleiigvassNteqvliaatsndlvyleigdgeldltstttlen 540
           ++d+qt+++ +v +++ql+q+Ts svrLv ++ k+l++eW+++++++i+vas+N++qv++a+ +++l+ylei+++el+++s t++e+
   Q: 434  VDDQQTFFCGNV-AHQQLIQITSTSVRLVTQEPKALVSEWREPKGKNISVASCNSSQVVVAV-GRALYYLEIQPQELRQISCTEMEH 518
           ************.************************************************9.************************ PP
   S: 541  evavldlinieddpnlsdleavglltdiskrililpdletiykeklggeiipRsilltefEnvtYlLialgdGalvsyildidtgde 627
           eva+ld+++++d++ +s l+a+gl+tdis+ril+lp++e+++ke+lggeiipRsil+t+fEn +YlL+algdGal+++ l i+tg +
   Q: 519  EVACLDITPLGDSNGMSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFENSHYLLCALGDGALFYFGLSIETGLL 605
           *************************************************************************************** PP
   S: 628  sdakksnlgtspgtlktfkslsttqvfassDrPtvIyssskkLvfSnVnlkeVqylCsldseaypdslalanngslvigtvddiqkl 714
           sd+kk++lgt+p++l+tf+slstt+vfa+sDrPtvIyss++kLvfSnVnlkeV+y+C+l+s++ypdslalann++l+igt+d+iqkl
   Q: 606  SDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKL 692
           *************************************************************************************** PP
   S: 715  kiRsiplgeslrriayqesvitfgvisdrreldf.klklkalrnnasilalvpdiennklfsdglrilelseleenevnfllvlDkn 800
           +iR++pl+es+r+i+yqe++++fgv+s+r+e+++ +++++alr++as++al+++++++klfs++++ +e+s++ee+ev++ll++D++
   Q: 693  HIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDaSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQH 779
           **********************************9**************************************************** PP
   S: 801  tfe..lllaqdlrewEtavsllSqklkdDseeyyvvktalvlpeenelkkgrilvfsvedslklkLltvaekkvkgavidlvklNgk 885
           tfe  +l+a+++ ++E+a+sl+S+kl++D+++y++v+ta+v+pee+e+k+gri+vf+++d+   kL+  aek+vkgav+++v++Ngk
   Q: 780  TFEdaVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFHYSDG---KLQSLAEKEVKGAVYSMVEFNGK 863
           **777********************************************************...*********************** PP
   S: 886  llaainseirlyewkvmgtdekelrkeCernntilaLtlktrkdfivVgDlmrsvtLllykdlegsfeEsardynlewmsaveilnd 972
           lla+ins++rlyew    t ekelr+eC+++n+i+aL++kt++dfi+VgDlmrsv Ll+yk +eg+feE+ard+n++wmsaveil+d
   Q: 864  LLASINSTVRLYEW----TAEKELRTECNHYNNIMALYVKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDD 946
           **************....********************************************************************* PP
   S: 973  diflgaencgNlfvvkkdikagltdeerslleevgefrlgefvevfrfgtlvlqdvgerevnrssevifgtengeigvilrlrrell 1059
           d+flgaen++Nlfv++kd +a++tdeer++l+evg f+lgefv+vf++g+lv+q++ge++++++++v+fgt+ng+ig++++l+++++
   Q: 947  DNFLGAENAFNLFVCQKD-SAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWY 1032
           ******************.******************************************************************** PP
   S: 1060 kflrnlestlkkvikrvakieHssyRsFetekrterasgfvdgdLiesilDlsrdkavdilkvl.yekrwnskkevsveeivKlvee 1145
           ++l +++++l+kvik+v+kieHs++RsF+te++te+a+gf+dgdLies+lD+sr+k+++++++l  ++++++k+e++v++++K+vee
   Q: 1033 NLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISR

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

LAGHFTSAED LNLLIAKNTR LEIYVVTPEG LRPVKEVGMY GKIAVMELFH PKGENKDLLF 60
ILTAKYNACI LEYKQSGESI DIITRAHGNV QDRIGRPSET GIIGIIDPEC RMIGLRLYDG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCGCAGGAC ACTTCACTTC CGCCGAGGAC CTGAACCTGC TGATAGCGAA GAACACCCGC 60
CTTGAGATCT ATGTGGTCAC GCCGGAGGGG CTGCGGCCCG TCAAGGAGGT GGGCATGTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR004871--Cleavage/polyA-sp_fac_asu_C
IPR031297--DDB1
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom

Pfam

PF03178--CPSF_A

Gene Ontology

GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0031465--C:Cul4B-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0000784--C:nuclear chromosome, telomeric region
GO:0005654--C:nucleoplasm
GO:0003684--F:damaged DNA binding
GO:0035518--P:histone H2A monoubiquitination
GO:0051702--P:interaction with symbiont
GO:0043066--P:negative regulation of apoptotic process
GO:0046726--P:positive regulation by virus of viral protein levels in host cell
GO:0045070--P:positive regulation of viral genome replication
GO:1902188--P:positive regulation of viral release from host cell
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:1901990--P:regulation of mitotic cell cycle phase transition
GO:0070914--P:UV-damage excision repair
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000120	Aegilops tauschii	49.66	0.00e+00	1100.00
IUUC-Aml-002096	Ailuropoda melanoleuca	97.06	0.00e+00	2210.00
IUUC-Atr-002742	Amborella trichopoda	52.04	0.00e+00	1152.00
IUUC-Apl-003624	Anas platyrhynchos	96.98	0.00e+00	2199.00
IUUC-Aca-005085	Anolis carolinensis	97.51	0.00e+00	2218.00
IUUC-Aly-005857	Arabidopsis lyrata	52.52	0.00e+00	1156.00
IUUC-Ath-006658	Arabidopsis thaliana	52.44	0.00e+00	1154.00
IUUC-Acl-008149	Aspergillus clavatus	27.06	2.00e-102	367.00
IUUC-Afl-008549	Aspergillus flavus	27.79	4.00e-107	382.00
IUUC-Afu-009076	Aspergillus fumigatus	27.06	2.00e-112	400.00
IUUC-Ani-009302	Aspergillus nidulans	27.05	2.00e-88	320.00
IUUC-Ang-009636	Aspergillus niger	28.06	1.00e-80	295.00
IUUC-Aor-010073	Aspergillus oryzae	27.82	1.00e-109	391.00
IUUC-Ate-010422	Aspergillus terreus	27.06	9.00e-102	365.00
IUUC-Ame-011643	Astyanax mexicanus	80.47	0.00e+00	1796.00
IUUC-Bgr-012164	Blumeria graminis	28.35	7.00e-73	268.00
IUUC-Bta-012494	Bos taurus	97.06	0.00e+00	2209.00
IUUC-Bci-013957	Botrytis cinerea	25.97	7.00e-88	318.00
IUUC-Bdi-014186	Brachypodium distachyon	52.17	0.00e+00	1145.00
IUUC-Bol-015922	Brassica oleracea	52.97	0.00e+00	1167.00
IUUC-Bra-017300	Brassica rapa	52.97	0.00e+00	1160.00
IUUC-Cel-018239	Caenorhabditis elegans	37.10	0.00e+00	766.00
IUUC-Cja-019165	Callithrix jacchus	96.98	0.00e+00	2208.00
IUUC-Cfa-020406	Canis familiaris	97.06	0.00e+00	2210.00
IUUC-Cpo-022154	Cavia porcellus	96.62	0.00e+00	2198.00
IUUC-Cre-022557	Chlamydomonas reinhardtii	40.24	0.00e+00	749.00
IUUC-Csa-024061	Chlorocebus sabaeus	96.98	0.00e+00	2208.00
IUUC-Cho-024554	Choloepus hoffmanni	90.94	0.00e+00	924.00
IUUC-Cin-025466	Ciona intestinalis	61.36	0.00e+00	1442.00
IUUC-Csv-026370	Ciona savignyi	60.20	0.00e+00	1309.00
IUUC-Cgl-026595	Colletotrichum gloeosporioides	25.81	7.00e-95	342.00
IUUC-Cme-027342	Cyanidioschyzon merolae	27.54	1.00e-113	404.00
IUUC-Dre-027448	Danio rerio	91.94	0.00e+00	1030.00
IUUC-Dno-029794	Dasypus novemcinctus	96.60	0.00e+00	2067.00
IUUC-Dor-030789	Dipodomys ordii	82.82	0.00e+00	956.00
IUUC-Dse-031491	Dothistroma septosporum	28.08	3.00e-112	399.00
IUUC-Dme-031940	Drosophila melanogaster	60.55	0.00e+00	1338.00
IUUC-Ete-032913	Echinops telfairi	78.46	0.00e+00	835.00
IUUC-Eca-033777	Equus caballus	96.35	0.00e+00	2184.00
IUUC-Eeu-034900	Erinaceus europaeus	94.63	0.00e+00	1094.00
IUUC-Fca-035869	Felis catus	97.06	0.00e+00	2210.00
IUUC-Fal-036777	Ficedula albicollis	97.51	0.00e+00	2215.00
IUUC-Fox-037954	Fusarium oxysporum	26.69	3.00e-101	363.00
IUUC-Fso-038292	Fusarium solani	26.09	1.00e-105	378.00
IUUC-Gmo-038815	Gadus morhua	81.56	0.00e+00	962.00
IUUC-Ggr-039907	Gaeumannomyces graminis	25.90	2.00e-94	340.00
IUUC-Gga-040995	Gallus gallus	97.42	0.00e+00	2218.00
IUUC-Gac-042390	Gasterosteus aculeatus	89.40	0.00e+00	1945.00
IUUC-Gma-042904	Glycine max	51.90	0.00e+00	1113.00
IUUC-Ggo-044891	Gorilla gorilla	96.63	0.00e+00	2199.00
IUUC-Hsa-046709	Homo sapiens	96.98	0.00e+00	2208.00
IUUC-Hvu-047504	Hordeum vulgare	51.90	0.00e+00	1127.00
IUUC-Itr-048678	Ictidomys tridecemlineatus	96.98	0.00e+00	2210.00
IUUC-Lch-050565	Latimeria chalumnae	93.61	0.00e+00	2142.00
IUUC-Lpe-051260	Leersia perrieri	52.35	0.00e+00	1145.00
IUUC-Loc-052091	Lepisosteus oculatus	82.42	0.00e+00	1481.00
IUUC-Lma-053246	Leptosphaeria maculans	25.26	8.00e-100	358.00
IUUC-Laf-053502	Loxodonta africana	96.80	0.00e+00	2204.00
IUUC-Mcc-054802	Macaca mulatta	97.04	0.00e+00	2191.00
IUUC-Meu-056808	Macropus eugenii	95.09	0.00e+00	1435.00
IUUC-Mor-057253	Magnaporthe oryzae	27.17	5.00e-61	229.00
IUUC-Mpo-057562	Magnaporthe poae	25.21	8.00e-93	335.00
IUUC-Mtr-057743	Medicago truncatula	51.02	0.00e+00	1123.00
IUUC-Mla-059154	Melampsora laricipopulina	24.22	4.00e-77	283.00
IUUC-Mga-059824	Meleagris gallopavo	97.12	0.00e+00	2112.00
IUUC-Mvi-060279	Microbotryum violaceum	27.09	2.00e-107	384.00
IUUC-Mmr-061215	Microcebus murinus	96.35	0.00e+00	2187.00
IUUC-Mdo-062028	Monodelphis domestica	95.68	0.00e+00	1858.00
IUUC-Mmu-064327	Mus musculus	96.98	0.00e+00	2207.00
IUUC-Mac-065445	Musa acuminata	52.52	0.00e+00	1127.00
IUUC-Mpu-065814	Mustela putorius furo	93.77	0.00e+00	2113.00
IUUC-Mlu-067136	Myotis lucifugus	96.98	0.00e+00	2203.00
IUUC-Nfi-068355	Neosartorya fischeri	27.06	5.00e-106	379.00
IUUC-Ncr-068620	Neurospora crassa	25.21	2.00e-86	314.00
IUUC-Nle-069566	Nomascus leucogenys	96.86	0.00e+00	2176.00
IUUC-Opr-070915	Ochotona princeps	88.87	0.00e+00	1825.00
IUUC-Ont-071753	Oreochromis niloticus	90.66	0.00e+00	2071.00
IUUC-Oan-073187	Ornithorhynchus anatinus	97.58	0.00e+00	2042.00
IUUC-Ocu-074619	Oryctolagus cuniculus	96.98	0.00e+00	2206.00
IUUC-Oba-075091	Oryza barthii	44.60	0.00e+00	879.00
IUUC-Obr-076425	Oryza brachyantha	52.73	0.00e+00	1147.00
IUUC-Ogu-078794	Oryza glumaepatula	52.61	0.00e+00	1153.00
IUUC-Oin-079725	Oryza indica	52.61	0.00e+00	1139.00
IUUC-Olo-080842	Oryza longistaminata	50.81	0.00e+00	1069.00
IUUC-Ome-081818	Oryza meridionalis	52.70	0.00e+00	1156.00
IUUC-Oni-082879	Oryza nivara	51.90	0.00e+00	1129.00
IUUC-Opu-083361	Oryza punctata	51.92	0.00e+00	1142.00
IUUC-Oru-084781	Oryza rufipogon	52.61	0.00e+00	1155.00
IUUC-Osa-086293	Oryza sativa	52.61	0.00e+00	1155.00
IUUC-Ola-086881	Oryzias latipes	89.36	0.00e+00	2040.00
IUUC-Olu-087674	Ostreococcus lucimarinus	44.91	0.00e+00	927.00
IUUC-Oga-089056	Otolemur garnettii	97.06	0.00e+00	2206.00
IUUC-Oar-089457	Ovis aries	97.20	0.00e+00	2175.00
IUUC-Ptr-091179	Pan troglodytes	97.06	0.00e+00	2209.00
IUUC-Pan-092019	Papio anubis	96.46	0.00e+00	2194.00
IUUC-Pma-094272	Petromyzon marinus	86.18	0.00e+00	1837.00
IUUC-Pno-094864	Phaeosphaeria nodorum	26.15	5.00e-109	389.00
IUUC-Ppa-095885	Physcomitrella patens	52.73	0.00e+00	1132.00
IUUC-Pfo-096083	Poecilia formosa	90.04	0.00e+00	2050.00
IUUC-Pab-098652	Pongo abelii	92.12	0.00e+00	2055.00
IUUC-Pop-099593	Populus trichocarpa	52.52	0.00e+00	1104.00
IUUC-Pca-100189	Procavia capensis	96.43	0.00e+00	1292.00
IUUC-Ppe-101987	Prunus persica	51.90	0.00e+00	1084.00
IUUC-Pva-102605	Pteropus vampyrus	96.89	0.00e+00	2205.00
IUUC-Pgr-103659	Puccinia graminis	24.10	2.00e-69	257.00
IUUC-Ptt-103884	Puccinia triticina	23.32	4.00e-57	216.00
IUUC-Pte-104233	Pyrenophora teres	26.73	1.00e-109	391.00
IUUC-Pyt-104454	Pyrenophora triticirepentis	26.82	3.00e-107	383.00
IUUC-Rno-106004	Rattus norvegicus	96.98	0.00e+00	2207.00
IUUC-Sha-106726	Sarcophilus harrisii	95.52	0.00e+00	2055.00
IUUC-Sja-107864	Schizosaccharomyces japonicus	23.89	8.00e-72	265.00
IUUC-Spo-108029	Schizosaccharomyces pombe	26.73	1.00e-97	351.00
IUUC-Ssl-108441	Sclerotinia sclerotiorum	25.39	7.00e-80	292.00
IUUC-Smo-108808	Selaginella moellendorffii	52.48	0.00e+00	1182.00
IUUC-Sit-109735	Setaria italica	52.73	0.00e+00	1144.00
IUUC-Sly-111520	Solanum lycopersicum	52.07	0.00e+00	1130.00
IUUC-Sar-113606	Sorex araneus	92.95	1.00e-131	464.00
IUUC-Sbi-114539	Sorghum bicolor	51.75	0.00e+00	1130.00
IUUC-Sre-114936	Sporisorium reilianum	25.50	4.00e-63	237.00
IUUC-Ssc-116038	Sus scrofa	96.89	0.00e+00	2205.00
IUUC-Tgu-117512	Taeniopygia guttata	97.15	0.00e+00	2207.00
IUUC-Tru-117593	Takifugu rubripes	88.98	0.00e+00	2031.00
IUUC-Tsy-119513	Tarsius syrichta	93.54	0.00e+00	1167.00
IUUC-Tni-120551	Tetraodon nigroviridis	84.86	0.00e+00	1694.00
IUUC-Tca-121505	Theobroma cacao	52.79	0.00e+00	1128.00
IUUC-Tre-122136	Trichoderma reesei	25.95	2.00e-98	353.00
IUUC-Tvi-122512	Trichoderma virens	24.94	2.00e-95	343.00
IUUC-Tae-124186	Triticum aestivum	51.82	0.00e+00	1126.00
IUUC-Tur-126451	Triticum urartu	52.29	0.00e+00	1043.00
IUUC-Tme-127057	Tuber melanosporum	28.99	7.00e-107	381.00
IUUC-Ttr-128891	Tursiops truncatus	92.06	0.00e+00	1445.00
IUUC-Uma-129583	Ustilago maydis	25.36	1.00e-53	205.00
IUUC-Vda-129870	Verticillium dahliae	25.02	4.00e-85	309.00
IUUC-Vpa-130117	Vicugna pacos	92.43	0.00e+00	1695.00
IUUC-Vvi-131033	Vitis vinifera	51.73	0.00e+00	1130.00
IUUC-Xtr-131987	Xenopus tropicalis	92.20	0.00e+00	2089.00
IUUC-Xma-134117	Xiphophorus maculatus	88.66	0.00e+00	2001.00
IUUC-Zma-134758	Zea mays	52.70	0.00e+00	1148.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence