iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117593

UUCD1 version

UUC-TaR-00922

Ensembl Protein ID

ENSTRUP00000042678.1

UniProt Accession

H2V0E8; H2V0E8_TAKRU

Protein Name

Uncharacterized protein

Gene Name

DDB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000016682.1	ENSTRUT00000042822.1	ENSTRUP00000042678.1
ENSTRUG00000016682.1	ENSTRUT00000042823.1	ENSTRUP00000042679.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DDB1	0	1715.1	1	1141

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DDB1

   S: 2    mldrYvvtarkpsavvklvvgnftshkelNLliaksnrieiflvtpeglrpvvevklegsiavlrlfrpknekkdllfilteryntl 88
           m+++Yvvta+kp+av+++++g+fts+++lNLliak++r+ei++vt+eglrpv+ev ++g+iav++lfrpk+e+kdllfilt +yn++
   Q: 1    MSYNYVVTAQKPTAVNACITGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTSKYNAC 87
           799************************************************************************************ PP
   S: 89   ilelrdidessevvtradgevlDdigrssdsGlinviepkirlialelyqglfklIvldndikelkafnirleelnvsdvkflillt 175
           ile+++ +es++++tra+g+v+D+igr+s++G+i++++p++r+i+l+ly+glfk+I+ld+d+ elka+nirleel+v+dv+fl++++
   Q: 88   ILEYKQNGESIDIITRAHGNVKDPIGRPSETGIIGIVDPECRMIGLRLYDGLFKVIPLDRDNRELKAYNIRLEELQVIDVHFLYGCQ 174
           *************************************************************************************** PP
   S: 176  qptgrvlviyqdddgkhlktyelslkdKeFvkis.kqesiekeaellipvpsqlvgvlvlgeesivyksadnykdvdPylirqstai 261
           +pt  v++iyqd++g+h+ktye+sl++KeF+k++ kqe++e+ea+++ipvp++++g++++g+esi+y+++d+y +++P++i+qst++
   Q: 175  APT--VCFIYQDPQGRHVKTYEVSLREKEFNKGPwKQENVEAEASMVIPVPEPFGGAIIIGQESITYHNGDKYLAIAPPTIKQSTIV 259
           ***..********************************************************************************** PP
   S: 262  ryervdnngirylLgdfdGelkllllsaeeemsG.vevkslkielLgeisiaesisyldngllfvgsrfgdsQlvklisestgkgsy 347
           +++rvd ng+rylLgd++G+l++lll++ee m+G v +k+l++elLge+siae+++yldng++fvgsr+gd Qlvkl+++s+++gs+
   Q: 260  CHNRVDPNGSRYLLGDMEGRLFMLLLEKEELMDGtVALKDLHVELLGETSIAECLTYLDNGVVFVGSRLGDPQLVKLNVDSNDQGSF 346
           *************************************************************************************** PP
   S: 348  vvilerfknlkpIvdlvvvdldrrgqgqvvtvsgaskdGslRvirlgigieelasvdlkgvigllslkstidestdnslvlafvset 434
           v ++e+f+nl+pIvd++vvdl+r+gqgq+vt+sga+k+GslR+ir+gigi+e+as+dl+g++gl++l+s+  ++td++lvl+fv++t
   Q: 347  VTVMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSEAGRETDDMLVLSFVGQT 433
           *************************************************************************************** PP
   S: 435  kvlnlntgeeledtelsgvlsdlqtlltqdvidykqllqvTsqsvrLvssqikrllkeWkaknleiigvassNteqvliaatsndlv 521
           +vl+l+ gee+e+tel g+++++qt+ + +v +++ql+q+Ts svrLv ++ k+l++eWk++++++i+va +N +qv++a+ +++l+
   Q: 434  RVLMLS-GEEVEETELPGFVDNQQTFYCGNV-AHNQLIQITSGSVRLVLQDSKALVSEWKEPQGRNISVAACNHTQVVLAV-GRALY 517
           ******.************************.************************************************9.***** PP
   S: 522  yleigdgeldltstttlenevavldlinieddpnlsdleavglltdiskrililpdletiykeklggeiipRsilltefEnvtYlLi 608
           yl+i +gel+++stt++e+eva+ld++++++    s l+avgl+tdis+r+l+lp ++ ++ke+lggeiipRsil+t+fE+  YlL+
   Q: 518  YLQILAGELKQISTTEMEHEVACLDITPLGEAGAESPLCAVGLWTDISARVLKLPCFTPLHKEMLGGEIIPRSILMTTFEGSYYLLC 604
           *************************************************************************************** PP
   S: 609  algdGalvsyildi.dtgdesdakksnlgtspgtlktfkslsttqvfassDrPtvIyssskkLvfSnVnlkeVqylCsldseaypds 694
           algdGal+++ ld  ++g +s+ kk++lgt+p++l+tf+slst +vfa+sDrPtvIyss++kLvfSnVnlkeV+y+C+l+se+ypds
   Q: 605  ALGDGALFYFGLDLqTAGALSECKKVTLGTQPTVLRTFRSLSTSNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSEGYPDS 691
           *************725699******************************************************************** PP
   S: 695  lalanngslvigtvddiqklkiRsiplgeslrriayqesvitfgvisdrreldf.klklkalrnnasilalvpdiennklfsdglri 780
           lalann++l+igt+d+iqkl+iR++pl+es+rri+yqe++++fgv+s+r e+++ ++ + + r++as++al+++++++klf +++  
   Q: 692  LALANNSTLTIGTIDEIQKLHIRTVPLYESPRRICYQEVSQCFGVLSSRVEIQDvSGTTSPVRPSASTQALSSSMSSSKLFPSSTSP 778
           ******************************************************9******************************** PP
   S: 781  lelseleenevnfllvlDkntfelllaqdlrewEtavsllSqklkdDseeyyvvktalvlpeenelkkgrilvfsvedslklkLltv 867
           +e s++ee+e ++llv+D++tfe+l+a+++ + E+a+s++S++l++D+++y+vv+ta+v+pee+e+k+gri+vf+++d+   kL+tv
   Q: 779  HESSFGEEVEIHSLLVVDQHTFEVLHAHQFLPSEYALSMVSCRLGKDPSVYFVVGTAMVYPEEAEPKQGRIIVFHYTDG---KLQTV 862
           *******************************************************************************...***** PP
   S: 868  aekkvkgavidlvklNgkllaainseirlyewkvmgtdekelrkeCernntilaLtlktrkdfivVgDlmrsvtLllykdlegsfeE 954
           aek+vkgav+++v++Ngklla+ins++rlyew    t ekelr+eC+++n+i+aL+lkt++dfi+VgDlmrsv Ll+yk +eg+feE
   Q: 863  AEKEVKGAVYSMVEFNGKLLASINSTVRLYEW----TAEKELRTECSHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEE 945
           ********************************....*************************************************** PP
   S: 955  sardynlewmsaveilnddiflgaencgNlfvvkkdikagltdeerslleevgefrlgefvevfrfgtlvlqdvgerevnrssevif 1041
           +ard+n++wmsaveil+dd+flgaen++Nlfv++kd +a++tde+r++l+evg f+lgefv+vf++g+lvlq++ge++++++++v+f
   Q: 946  IARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKD-SAATTDEDRQHLQEVGVFHLGEFVNVFCHGSLVLQNLGETSTPTQGSVLF 1031
           ************************************.************************************************** PP
   S: 1042 gtengeigvilrlrrellkflrnlestlkkvikrvakieHssyRsFetekrterasgfvdgdLiesilDlsrdkavdilkvl.yekr 1127
           gt+ g+ig++++l++ + ++l +l+++l+kvik+v+kieHs +RsF+te++te+a+gf+dgdLies+lDl r k+++++++l  +++
   Q: 1032 GTVTGMIGLVTSLSEGWHSLLLDLQNRLNKVIKSVGKIEHSTWRSFHTERKTEQA

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MSYNYVVTAQ KPTAVNACIT GHFTSAEDLN LLIAKNTRLE IYVVTAEGLR PVKEVGMYGK 60
IAVMELFRPK GESKDLLFIL TSKYNACILE YKQNGESIDI ITRAHGNVKD PIGRPSETGI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGTGAGAAT AAGACACTTC GCTTGTGTTT GTATATTGTC GTTGTAAGAA ATGTCGTACA 60
ACTACGTGGT GACAGCACAG AAACCGACGG CAGTGAATGC CTGCATAACG GGTAGGTATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR004871--Cleavage/polyA-sp_fac_asu_C
IPR031297--DDB1
IPR015943--WD40/YVTN_repeat-like_dom
IPR017986--WD40_repeat_dom

Pfam

PF03178--CPSF_A

Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0006289--P:nucleotide-excision repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000120	Aegilops tauschii	48.87	0.00e+00	1105.00
IUUC-Aml-002096	Ailuropoda melanoleuca	89.83	0.00e+00	2102.00
IUUC-Atr-002742	Amborella trichopoda	51.87	0.00e+00	1162.00
IUUC-Apl-003624	Anas platyrhynchos	88.51	0.00e+00	2041.00
IUUC-Aca-005085	Anolis carolinensis	89.31	0.00e+00	2088.00
IUUC-Aly-005857	Arabidopsis lyrata	51.96	0.00e+00	1165.00
IUUC-Ath-006658	Arabidopsis thaliana	52.05	0.00e+00	1163.00
IUUC-Acl-008149	Aspergillus clavatus	27.36	9.00e-110	391.00
IUUC-Afl-008549	Aspergillus flavus	28.54	4.00e-113	402.00
IUUC-Afu-009076	Aspergillus fumigatus	27.75	8.00e-119	422.00
IUUC-Ani-009302	Aspergillus nidulans	27.55	5.00e-92	332.00
IUUC-Ang-009636	Aspergillus niger	28.44	3.00e-84	306.00
IUUC-Aor-010073	Aspergillus oryzae	28.57	8.00e-118	418.00
IUUC-Ate-010422	Aspergillus terreus	27.28	4.00e-107	382.00
IUUC-Ame-011643	Astyanax mexicanus	84.91	0.00e+00	1915.00
IUUC-Bgr-012164	Blumeria graminis	26.99	3.00e-100	360.00
IUUC-Bta-012494	Bos taurus	89.75	0.00e+00	2102.00
IUUC-Bci-013957	Botrytis cinerea	26.34	5.00e-89	322.00
IUUC-Bdi-014186	Brachypodium distachyon	51.66	0.00e+00	1149.00
IUUC-Bol-015922	Brassica oleracea	52.31	0.00e+00	1176.00
IUUC-Bra-017300	Brassica rapa	52.31	0.00e+00	1170.00
IUUC-Cel-018239	Caenorhabditis elegans	37.12	0.00e+00	763.00
IUUC-Cja-019165	Callithrix jacchus	89.75	0.00e+00	2100.00
IUUC-Cfa-020406	Canis familiaris	89.83	0.00e+00	2102.00
IUUC-Cpo-022154	Cavia porcellus	89.75	0.00e+00	2100.00
IUUC-Cre-022557	Chlamydomonas reinhardtii	41.17	0.00e+00	787.00
IUUC-Csa-024061	Chlorocebus sabaeus	89.75	0.00e+00	2100.00
IUUC-Cho-024554	Choloepus hoffmanni	82.61	0.00e+00	851.00
IUUC-Cin-025466	Ciona intestinalis	61.23	0.00e+00	1453.00
IUUC-Csv-026370	Ciona savignyi	60.28	0.00e+00	1308.00
IUUC-Cgl-026595	Colletotrichum gloeosporioides	25.61	9.00e-97	348.00
IUUC-Cme-027342	Cyanidioschyzon merolae	27.96	6.00e-114	405.00
IUUC-Dre-027448	Danio rerio	94.79	0.00e+00	1044.00
IUUC-Dno-029794	Dasypus novemcinctus	90.15	0.00e+00	1986.00
IUUC-Dor-030789	Dipodomys ordii	74.75	0.00e+00	872.00
IUUC-Dse-031491	Dothistroma septosporum	28.90	7.00e-116	412.00
IUUC-Dme-031940	Drosophila melanogaster	60.03	0.00e+00	1349.00
IUUC-Ete-032913	Echinops telfairi	72.48	0.00e+00	781.00
IUUC-Eca-033777	Equus caballus	89.31	0.00e+00	2085.00
IUUC-Eeu-034900	Erinaceus europaeus	85.88	0.00e+00	1012.00
IUUC-Fca-035869	Felis catus	89.83	0.00e+00	2102.00
IUUC-Fal-036777	Ficedula albicollis	89.16	0.00e+00	2082.00
IUUC-Fox-037954	Fusarium oxysporum	26.56	1.00e-103	371.00
IUUC-Fso-038292	Fusarium solani	25.94	2.00e-107	384.00
IUUC-Gmo-038815	Gadus morhua	89.35	0.00e+00	1028.00
IUUC-Ggr-039907	Gaeumannomyces graminis	26.14	4.00e-93	336.00
IUUC-Gga-040995	Gallus gallus	89.48	0.00e+00	2098.00
IUUC-Gac-042390	Gasterosteus aculeatus	95.79	0.00e+00	2086.00
IUUC-Gma-042743	Glycine max	51.83	0.00e+00	1137.00
IUUC-Ggo-044891	Gorilla gorilla	89.60	0.00e+00	2098.00
IUUC-Hsa-046709	Homo sapiens	89.75	0.00e+00	2100.00
IUUC-Hvu-047504	Hordeum vulgare	51.05	0.00e+00	1130.00
IUUC-Itr-048678	Ictidomys tridecemlineatus	89.75	0.00e+00	2102.00
IUUC-Lch-050565	Latimeria chalumnae	89.68	0.00e+00	2085.00
IUUC-Lpe-051260	Leersia perrieri	51.87	0.00e+00	1149.00
IUUC-Loc-052091	Lepisosteus oculatus	87.04	0.00e+00	1548.00
IUUC-Lma-053246	Leptosphaeria maculans	26.51	1.00e-105	378.00
IUUC-Laf-053502	Loxodonta africana	89.66	0.00e+00	2100.00
IUUC-Mcc-054802	Macaca mulatta	89.75	0.00e+00	2084.00
IUUC-Meu-056808	Macropus eugenii	87.60	0.00e+00	1333.00
IUUC-Mor-057253	Magnaporthe oryzae	25.28	3.00e-79	290.00
IUUC-Mpo-057562	Magnaporthe poae	25.61	3.00e-92	333.00
IUUC-Mtr-057743	Medicago truncatula	51.13	0.00e+00	1140.00
IUUC-Mla-059154	Melampsora laricipopulina	24.36	8.00e-78	285.00
IUUC-Mga-059824	Meleagris gallopavo	88.74	0.00e+00	1956.00
IUUC-Mvi-060279	Microbotryum violaceum	26.95	7.00e-111	395.00
IUUC-Mmr-061215	Microcebus murinus	89.40	0.00e+00	2086.00
IUUC-Mdo-062028	Monodelphis domestica	87.95	0.00e+00	1724.00
IUUC-Mmu-064327	Mus musculus	89.83	0.00e+00	2101.00
IUUC-Mac-065445	Musa acuminata	52.05	0.00e+00	1130.00
IUUC-Mpu-065814	Mustela putorius furo	86.85	0.00e+00	2009.00
IUUC-Mlu-067136	Myotis lucifugus	89.92	0.00e+00	2097.00
IUUC-Nfi-068355	Neosartorya fischeri	27.59	6.00e-112	399.00
IUUC-Ncr-068620	Neurospora crassa	25.81	3.00e-91	330.00
IUUC-Nle-069566	Nomascus leucogenys	89.66	0.00e+00	2072.00
IUUC-Opr-070915	Ochotona princeps	81.20	0.00e+00	1684.00
IUUC-Ont-071753	Oreochromis niloticus	97.11	0.00e+00	2220.00
IUUC-Oan-073187	Ornithorhynchus anatinus	89.35	0.00e+00	1892.00
IUUC-Ocu-074619	Oryctolagus cuniculus	89.92	0.00e+00	2105.00
IUUC-Oba-075091	Oryza barthii	49.52	0.00e+00	794.00
IUUC-Obr-076425	Oryza brachyantha	52.29	0.00e+00	1143.00
IUUC-Ogu-078794	Oryza glumaepatula	51.79	0.00e+00	1150.00
IUUC-Oin-079725	Oryza indica	51.44	0.00e+00	1135.00
IUUC-Olo-080842	Oryza longistaminata	49.82	0.00e+00	1050.00
IUUC-Ome-081818	Oryza meridionalis	51.87	0.00e+00	1153.00
IUUC-Oni-082879	Oryza nivara	51.18	0.00e+00	1129.00
IUUC-Opu-083361	Oryza punctata	51.29	0.00e+00	1142.00
IUUC-Oru-084781	Oryza rufipogon	51.79	0.00e+00	1152.00
IUUC-Osa-086293	Oryza sativa	51.79	0.00e+00	1152.00
IUUC-Ola-086881	Oryzias latipes	96.50	0.00e+00	2217.00
IUUC-Olu-087674	Ostreococcus lucimarinus	45.75	0.00e+00	941.00
IUUC-Oga-089056	Otolemur garnettii	89.92	0.00e+00	2105.00
IUUC-Oar-089457	Ovis aries	89.95	0.00e+00	2072.00
IUUC-Ptr-091179	Pan troglodytes	89.58	0.00e+00	2062.00
IUUC-Pan-092019	Papio anubis	89.44	0.00e+00	2093.00
IUUC-Psi-093407	Pelodiscus sinensis	88.98	0.00e+00	2051.00
IUUC-Pma-094272	Petromyzon marinus	85.77	0.00e+00	1822.00
IUUC-Pno-094864	Phaeosphaeria nodorum	26.88	5.00e-110	392.00
IUUC-Ppa-095885	Physcomitrella patens	52.65	0.00e+00	1149.00
IUUC-Pfo-096083	Poecilia formosa	97.02	0.00e+00	2216.00
IUUC-Pab-098652	Pongo abelii	85.79	0.00e+00	1981.00
IUUC-Pop-099593	Populus trichocarpa	52.18	0.00e+00	1115.00
IUUC-Pca-100189	Procavia capensis	87.48	0.00e+00	1184.00
IUUC-Ppe-101987	Prunus persica	51.92	0.00e+00	1102.00
IUUC-Pva-102605	Pteropus vampyrus	89.66	0.00e+00	2098.00
IUUC-Pgr-103659	Puccinia graminis	24.73	6.00e-77	283.00
IUUC-Ptt-103884	Puccinia triticina	23.17	2.00e-59	224.00
IUUC-Pte-104233	Pyrenophora teres	26.68	1.00e-115	410.00
IUUC-Pyt-104454	Pyrenophora triticirepentis	27.25	2.00e-114	407.00
IUUC-Rno-106004	Rattus norvegicus	89.92	0.00e+00	2105.00
IUUC-Sha-106726	Sarcophilus harrisii	87.21	0.00e+00	1901.00
IUUC-Sja-107864	Schizosaccharomyces japonicus	24.51	3.00e-73	270.00
IUUC-Spo-108029	Schizosaccharomyces pombe	26.23	6.00e-101	362.00
IUUC-Ssl-108441	Sclerotinia sclerotiorum	26.02	3.00e-81	296.00
IUUC-Smo-108808	Selaginella moellendorffii	52.40	0.00e+00	1194.00
IUUC-Sit-109735	Setaria italica	51.90	0.00e+00	1144.00
IUUC-Sly-111520	Solanum lycopersicum	51.65	0.00e+00	1133.00
IUUC-Sar-113606	Sorex araneus	84.65	2.00e-118	420.00
IUUC-Sbi-114539	Sorghum bicolor	51.12	0.00e+00	1133.00
IUUC-Sre-114936	Sporisorium reilianum	25.42	2.00e-64	241.00
IUUC-Ssc-116038	Sus scrofa	89.75	0.00e+00	2099.00
IUUC-Tgu-117512	Taeniopygia guttata	89.22	0.00e+00	2086.00
IUUC-Tsy-119513	Tarsius syrichta	84.70	0.00e+00	1071.00
IUUC-Tni-120551	Tetraodon nigroviridis	92.72	0.00e+00	1828.00
IUUC-Tca-121505	Theobroma cacao	52.53	0.00e+00	1139.00
IUUC-Tre-122136	Trichoderma reesei	26.44	4.00e-105	376.00
IUUC-Tvi-122512	Trichoderma virens	26.23	2.00e-103	370.00
IUUC-Tae-122891	Triticum aestivum	50.96	0.00e+00	1130.00
IUUC-Tur-126451	Triticum urartu	51.34	0.00e+00	1025.00
IUUC-Tme-127057	Tuber melanosporum	29.63	3.00e-114	406.00
IUUC-Ttr-128891	Tursiops truncatus	84.35	0.00e+00	1333.00
IUUC-Uma-129583	Ustilago maydis	25.62	7.00e-52	199.00
IUUC-Vda-129870	Verticillium dahliae	25.34	1.00e-89	325.00
IUUC-Vpa-130117	Vicugna pacos	85.28	0.00e+00	1583.00
IUUC-Vvi-131033	Vitis vinifera	51.48	0.00e+00	1136.00
IUUC-Xtr-131987	Xenopus tropicalis	87.50	0.00e+00	2030.00
IUUC-Xma-134117	Xiphophorus maculatus	95.02	0.00e+00	2163.00
IUUC-Zma-134758	Zea mays	52.05	0.00e+00	1151.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence