iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088055

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

AAQR03067909

Gene Name

UCHL3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000017114.2	ENSOGAT00000017118.2	ENSOGAP00000015328.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	5.20e-71	239.7	3	231

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 5    vkewleLesdPglftl.lvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffak 92
           +++wl+Le++P++ ++ +++++g++ ++q+ ++y++dpe l+++++pv+++lllF+i+ek+e +r+++   ++++++++d++++++f+k
   Q: 3    GQRWLPLEANPEVTNQqFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEE--EEKIKSQGQDVTSSVYFMK 89
           589***********95489**********************************************766..5589*************** PP
   S: 93   qvigNsCatyAllsvllncedkl.ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhf 180
           q+i+N+C+t++l+++++n++dk+ ++ G+tl++++e++ ++spe++a+ l+n ++++++h++ a+++++++p+ +       +k  +hf
   Q: 90   QTISNACGTIGLIHAIANNKDKMhFESGSTLKKFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTEAPSID-------EKVDLHF 171
           ************************************************************************888.......8899*** PP
   S: 181  vsyvningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesdeirfnllaivad 244
           +++v+++g+lyeldg+kpfP+++g++++++ l+d+++v+++f+er    + de+rfn++a++a+
   Q: 172  IALVHVDGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMER----DPDELRFNAIALSAA 231
           *********************************************....***********9875 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MEGQRWLPLE ANPEVTNQQF LKQLGLHPNW QFVDVYGMDP ELLSMVPRPV CAVLLLFPIT 60
EKYEVFRTEE EEKIKSQGQD VTSSVYFMKQ TISNACGTIG LIHAIANNKD KMHFESGSTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGGTC AACGCTGGCT GCCCCTGGAG GCCAATCCCG AGGTGAGCGC AACTCGGGTC 60
CGGCCTGGGG CTGTGGGCAG GGGCAGTGGG AGCCCAGCTG TTGCAACTAA TCCACAGCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000360	Aegilops tauschii	43.88	4.00e-52	197.00
IUUC-Aml-001344	Ailuropoda melanoleuca	99.57	4.00e-136	476.00
IUUC-Atr-002931	Amborella trichopoda	48.39	9.00e-49	186.00
IUUC-Apl-003949	Anas platyrhynchos	87.32	7.00e-105	372.00
IUUC-Aca-004924	Anolis carolinensis	83.12	3.00e-117	414.00
IUUC-Aly-005939	Arabidopsis lyrata	50.88	1.00e-58	219.00
IUUC-Ath-006827	Arabidopsis thaliana	50.66	4.00e-59	221.00
IUUC-Ago-007950	Ashbya gossypii	34.98	5.00e-26	110.00
IUUC-Acl-008305	Aspergillus clavatus	39.46	7.00e-40	157.00
IUUC-Afl-008611	Aspergillus flavus	40.08	2.00e-42	165.00
IUUC-Afu-008945	Aspergillus fumigatus	40.51	5.00e-42	164.00
IUUC-Ani-009339	Aspergillus nidulans	40.34	9.00e-43	166.00
IUUC-Ang-009691	Aspergillus niger	38.56	7.00e-42	163.00
IUUC-Aor-009961	Aspergillus oryzae	40.08	2.00e-42	165.00
IUUC-Ate-010316	Aspergillus terreus	40.68	4.00e-43	167.00
IUUC-Ame-011157	Astyanax mexicanus	72.73	3.00e-100	357.00
IUUC-Bgr-012125	Blumeria graminis	36.55	2.00e-38	152.00
IUUC-Bta-012673	Bos taurus	98.70	4.00e-135	473.00
IUUC-Bci-013734	Botrytis cinerea	37.45	4.00e-41	160.00
IUUC-Bdi-014330	Brachypodium distachyon	45.61	4.00e-55	207.00
IUUC-Bol-015214	Brassica oleracea	52.63	3.00e-62	231.00
IUUC-Bra-017491	Brassica rapa	53.07	6.00e-62	230.00
IUUC-Cel-018302	Caenorhabditis elegans	39.91	3.00e-34	137.00
IUUC-Cfa-020371	Canis familiaris	97.37	2.00e-107	381.00
IUUC-Cpo-022036	Cavia porcellus	96.10	4.00e-130	456.00
IUUC-Cre-022599	Chlamydomonas reinhardtii	43.98	7.00e-37	146.00
IUUC-Csa-023854	Chlorocebus sabaeus	98.70	2.00e-134	471.00
IUUC-Cin-025545	Ciona intestinalis	49.56	2.00e-65	241.00
IUUC-Cgl-026409	Colletotrichum gloeosporioides	34.32	6.00e-31	127.00
IUUC-Cne-026914	Cryptococcus neoformans	35.04	2.00e-30	125.00
IUUC-Cme-027216	Cyanidioschyzon merolae	37.22	7.00e-27	113.00
IUUC-Dre-028356	Danio rerio	74.03	6.00e-102	362.00
IUUC-Dse-031461	Dothistroma septosporum	40.34	9.00e-38	149.00
IUUC-Dme-032146	Drosophila melanogaster	50.44	6.00e-61	226.00
IUUC-Eca-033220	Equus caballus	99.13	5.00e-135	473.00
IUUC-Fca-036421	Felis catus	99.57	4.00e-136	476.00
IUUC-Fal-036773	Ficedula albicollis	86.70	4.00e-105	374.00
IUUC-Fox-037830	Fusarium oxysporum	36.64	7.00e-40	157.00
IUUC-Fso-038259	Fusarium solani	36.52	5.00e-38	153.00
IUUC-Gmo-039468	Gadus morhua	68.40	3.00e-84	304.00
IUUC-Ggr-039832	Gaeumannomyces graminis	36.96	4.00e-36	144.00
IUUC-Gga-041205	Gallus gallus	85.28	1.00e-110	392.00
IUUC-Gac-041629	Gasterosteus aculeatus	68.12	1.00e-86	311.00
IUUC-Gma-043057	Glycine max	49.56	2.00e-52	198.00
IUUC-Ggo-044533	Gorilla gorilla	100.00	4.00e-138	483.00
IUUC-Hsa-046754	Homo sapiens	99.57	4.00e-136	476.00
IUUC-Hvu-047176	Hordeum vulgare	40.87	1.00e-42	166.00
IUUC-Itr-047992	Ictidomys tridecemlineatus	96.86	2.00e-89	320.00
IUUC-Kpa-049123	Komagataella pastoris	36.92	2.00e-31	129.00
IUUC-Lch-049685	Latimeria chalumnae	78.17	2.00e-108	384.00
IUUC-Lpe-051377	Leersia perrieri	45.10	7.00e-46	176.00
IUUC-Loc-051988	Lepisosteus oculatus	76.19	1.00e-104	372.00
IUUC-Lma-053316	Leptosphaeria maculans	40.09	3.00e-41	161.00
IUUC-Laf-053985	Loxodonta africana	98.70	1.00e-136	478.00
IUUC-Mcc-055888	Macaca mulatta	97.40	2.00e-132	464.00
IUUC-Mor-057271	Magnaporthe oryzae	36.96	5.00e-40	157.00
IUUC-Mpo-057343	Magnaporthe poae	32.05	6.00e-21	93.60
IUUC-Mtr-057713	Medicago truncatula	48.46	2.00e-52	198.00
IUUC-Mla-058942	Melampsora laricipopulina	45.18	4.00e-46	177.00
IUUC-Mga-059702	Meleagris gallopavo	86.85	2.00e-104	370.00
IUUC-Mvi-060249	Microbotryum violaceum	44.10	1.00e-40	159.00
IUUC-Mmr-061284	Microcebus murinus	99.37	5.00e-91	327.00
IUUC-Mdo-062639	Monodelphis domestica	79.55	2.00e-121	428.00
IUUC-Mmu-063299	Mus musculus	97.84	3.00e-134	470.00
IUUC-Mac-065075	Musa acuminata	45.65	1.00e-52	199.00
IUUC-Mpu-066769	Mustela putorius furo	99.57	4.00e-136	476.00
IUUC-Mlu-066937	Myotis lucifugus	96.54	3.00e-131	460.00
IUUC-Nfi-068320	Neosartorya fischeri	40.59	5.00e-43	167.00
IUUC-Ncr-068673	Neurospora crassa	38.79	3.00e-44	171.00
IUUC-Nle-069175	Nomascus leucogenys	100.00	1.00e-124	438.00
IUUC-Opr-070652	Ochotona princeps	67.60	3.00e-84	304.00
IUUC-Ont-072170	Oreochromis niloticus	70.31	4.00e-88	317.00
IUUC-Oan-073247	Ornithorhynchus anatinus	92.98	4.00e-58	215.00
IUUC-Ocu-074422	Oryctolagus cuniculus	97.84	1.00e-134	471.00
IUUC-Oba-075098	Oryza barthii	41.85	6.00e-49	186.00
IUUC-Obr-076041	Oryza brachyantha	44.98	1.00e-53	202.00
IUUC-Ogl-076980	Oryza glaberrima	45.41	2.00e-53	201.00
IUUC-Ogu-078978	Oryza glumaepatula	38.19	2.00e-46	178.00
IUUC-Oin-079285	Oryza indica	41.41	3.00e-48	184.00
IUUC-Olo-080671	Oryza longistaminata	41.85	2.00e-48	185.00
IUUC-Ome-081428	Oryza meridionalis	40.97	5.00e-47	180.00
IUUC-Oni-082406	Oryza nivara	41.85	6.00e-49	186.00
IUUC-Opu-083305	Oryza punctata	41.85	2.00e-47	181.00
IUUC-Oru-084969	Oryza rufipogon	41.85	6.00e-49	186.00
IUUC-Osa-085830	Oryza sativa	45.41	2.00e-53	201.00
IUUC-Ola-086893	Oryzias latipes	68.12	2.00e-84	305.00
IUUC-Olu-087858	Ostreococcus lucimarinus	44.74	2.00e-51	194.00
IUUC-Oar-090319	Ovis aries	98.27	1.00e-134	471.00
IUUC-Pan-092714	Papio anubis	99.13	7.00e-137	479.00
IUUC-Psi-094036	Pelodiscus sinensis	87.32	7.00e-105	372.00
IUUC-Pma-094412	Petromyzon marinus	64.52	7.00e-54	202.00
IUUC-Pno-094997	Phaeosphaeria nodorum	36.08	1.00e-33	136.00
IUUC-Ppa-095519	Physcomitrella patens	50.88	5.00e-63	233.00
IUUC-Pfo-096182	Poecilia formosa	67.53	5.00e-87	313.00
IUUC-Pab-098216	Pongo abelii	100.00	3.00e-83	300.00
IUUC-Pop-099282	Populus trichocarpa	48.90	2.00e-52	198.00
IUUC-Ppe-101332	Prunus persica	48.02	1.00e-54	206.00
IUUC-Pgr-103430	Puccinia graminis	47.28	1.00e-49	189.00
IUUC-Ptt-103955	Puccinia triticina	48.93	4.00e-50	191.00
IUUC-Pte-104414	Pyrenophora teres	38.72	3.00e-38	151.00
IUUC-Pyt-104753	Pyrenophora triticirepentis	33.89	2.00e-33	135.00
IUUC-Rno-105096	Rattus norvegicus	96.97	4.00e-133	466.00
IUUC-Sce-106412	Saccharomyces cerevisiae	36.73	7.00e-27	113.00
IUUC-Sha-106677	Sarcophilus harrisii	93.58	2.00e-120	424.00
IUUC-Sja-107753	Schizosaccharomyces japonicus	30.81	3.00e-25	108.00
IUUC-Spo-108322	Schizosaccharomyces pombe	30.87	5.00e-25	107.00
IUUC-Ssl-108641	Sclerotinia sclerotiorum	37.45	2.00e-37	149.00
IUUC-Smo-108914	Selaginella moellendorffii	48.93	6.00e-53	200.00
IUUC-Sit-110163	Setaria italica	47.21	3.00e-54	205.00
IUUC-Sly-111613	Solanum lycopersicum	49.56	5.00e-61	227.00
IUUC-Stu-112526	Solanum tuberosum	50.66	1.00e-56	212.00
IUUC-Sbi-114545	Sorghum bicolor	46.52	4.00e-52	197.00
IUUC-Sre-114961	Sporisorium reilianum	42.31	4.00e-39	154.00
IUUC-Ssc-115255	Sus scrofa	97.64	5.00e-123	432.00
IUUC-Tgu-117003	Taeniopygia guttata	85.71	3.00e-111	393.00
IUUC-Tru-118330	Takifugu rubripes	62.50	2.00e-67	250.00
IUUC-Tsy-119488	Tarsius syrichta	98.25	2.00e-63	234.00
IUUC-Tni-120042	Tetraodon nigroviridis	63.78	2.00e-69	256.00
IUUC-Tca-120976	Theobroma cacao	47.58	1.00e-54	206.00
IUUC-Tre-122149	Trichoderma reesei	38.53	4.00e-42	164.00
IUUC-Tvi-122450	Trichoderma virens	38.53	5.00e-42	164.00
IUUC-Tae-122693	Triticum aestivum	45.02	1.00e-52	199.00
IUUC-Tur-126250	Triticum urartu	43.88	1.00e-51	196.00
IUUC-Tme-126961	Tuber melanosporum	36.86	9.00e-35	140.00
IUUC-Uma-129382	Ustilago maydis	41.20	8.00e-42	163.00
IUUC-Vda-129678	Verticillium dahliae	31.93	1.00e-30	126.00
IUUC-Vpa-130783	Vicugna pacos	99.13	1.00e-63	236.00
IUUC-Vvi-131661	Vitis vinifera	47.83	6.00e-56	210.00
IUUC-Xtr-132428	Xenopus tropicalis	74.03	2.00e-105	374.00
IUUC-Xma-134245	Xiphophorus maculatus	66.81	7.00e-87	313.00
IUUC-Yli-134570	Yarrowia lipolytica	35.74	3.00e-35	141.00
IUUC-Zma-134740	Zea mays	45.65	7.00e-54	203.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence