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Tag Content
iUUCD ID IUUC-Oar-090195
Ensembl Protein ID ENSOARP00000013825.1
UniProt Accession W5PTP4; W5PTP4_SHEEP
Genbank Protein ID ENSOARP00000013825
Protein Name Uncharacterized protein
Genbank Nucleotide ID AMGL01005673
Gene Name ITSN1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOARG00000012903.1 ENSOART00000014030.1 ENSOARP00000013825.1
ENSOARG00000012903.1 ENSOART00000014032.1 ENSOARP00000013827.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 2.10e-66 220.0 1161 1212
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v+ +ydy+aqnddeL + kG v+ v+   ++d +W+kg  e +g+ GlfP+n+v+
   Q: 1161 QVIGMYDYTAQNDDELAFSKGQVINVL--SKEDPDWWKG--EVHGQVGLFPSNYVK 1212
           46668**********************..889*******..9*************8 PP
   
Organism Ovis aries
Protein Sequence
(Fasta)
MAQFPTPFGG SLDIWAITVE ERAKHDQQFH SLKPISGFIT GDQARNFFFQ SGLPQPVLAQ 60
IWALADMNND GRMDQVEFSI AMKLIKLKLQ GYQLPSALPP VMKQQPVAIS SAPAFGMGGI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Oar-090195|UBD,SH3|Ovis aries
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGTCGGTTA GCAAGGTGAA AGTAACAGAA CCATGGCTCA GTTTCCCACA CCTTTTGGTG 60
GTAAGTTTTC AAAGATTTTT TTCTTTTTTT TAAAATCTAC TTTGGAACTG TAGTTTTAAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Oar-090195|UBD,SH3|Ovis aries
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR001331--GDS_CDC24_CS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain
PROSITE

PS50004--C2
PS00741--DH_1
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3
Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF14604--SH3_9
PRINTS

PR00452--SH3DOMAIN
SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3
Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030139--C:endocytic vesicle
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0019209--F:kinase activator activity
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000722 Aegilops tauschii 41.67 3.00e-14 75.10
IUUC-Aml-001218 Ailuropoda melanoleuca 95.48 0.00e+00 2413.00
IUUC-Atr-002491 Amborella trichopoda 32.85 3.00e-13 71.20
IUUC-Apl-003335 Anas platyrhynchos 91.06 0.00e+00 2279.00
IUUC-Aca-005130 Anolis carolinensis 88.68 0.00e+00 2244.00
IUUC-Ago-007935 Ashbya gossypii 34.33 1.00e-13 71.60
IUUC-Ang-009722 Aspergillus niger 31.45 2.00e-16 80.90
IUUC-Ame-011878 Astyanax mexicanus 75.33 0.00e+00 1934.00
IUUC-Bta-012863 Bos taurus 98.33 0.00e+00 2416.00
IUUC-Bdi-014016 Brachypodium distachyon 41.67 5.00e-14 73.60
IUUC-Cja-019012 Callithrix jacchus 95.64 0.00e+00 2368.00
IUUC-Cfa-020272 Canis familiaris 95.40 0.00e+00 2424.00
IUUC-Cpo-021352 Cavia porcellus 88.01 0.00e+00 2855.00
IUUC-Cho-024969 Choloepus hoffmanni 84.07 0.00e+00 1899.00
IUUC-Cin-025435 Ciona intestinalis 44.82 0.00e+00 978.00
IUUC-Csv-026290 Ciona savignyi 57.89 0.00e+00 783.00
IUUC-Cme-027247 Cyanidioschyzon merolae 26.59 9.00e-11 62.00
IUUC-Dre-028623 Danio rerio 77.12 0.00e+00 1950.00
IUUC-Dno-030044 Dasypus novemcinctus 94.40 0.00e+00 2373.00
IUUC-Dor-030272 Dipodomys ordii 87.77 0.00e+00 2095.00
IUUC-Ete-032927 Echinops telfairi 98.40 0.00e+00 1039.00
IUUC-Eca-033469 Equus caballus 95.88 0.00e+00 2377.00
IUUC-Eeu-034977 Erinaceus europaeus 91.05 0.00e+00 1125.00
IUUC-Fca-036419 Felis catus 95.08 0.00e+00 2394.00
IUUC-Fal-037236 Ficedula albicollis 89.87 0.00e+00 2277.00
IUUC-Gmo-039632 Gadus morhua 70.58 0.00e+00 1691.00
IUUC-Gga-040835 Gallus gallus 89.13 0.00e+00 2234.00
IUUC-Gac-041948 Gasterosteus aculeatus 71.00 0.00e+00 1811.00
IUUC-Hsa-045699 Homo sapiens 95.88 0.00e+00 2429.00
IUUC-Hvu-047530 Hordeum vulgare 33.14 1.00e-14 75.10
IUUC-Itr-048773 Ictidomys tridecemlineatus 92.01 0.00e+00 2333.00
IUUC-Lch-050502 Latimeria chalumnae 77.79 0.00e+00 1651.00
IUUC-Lpe-051250 Leersia perrieri 41.67 2.00e-14 74.70
IUUC-Loc-052613 Lepisosteus oculatus 80.92 0.00e+00 1988.00
IUUC-Laf-053608 Loxodonta africana 94.27 0.00e+00 2374.00
IUUC-Mcc-055720 Macaca mulatta 95.24 0.00e+00 2383.00
IUUC-Meu-056445 Macropus eugenii 83.92 0.00e+00 1691.00
IUUC-Mmr-061258 Microcebus murinus 95.16 0.00e+00 2357.00
IUUC-Mdo-062019 Monodelphis domestica 90.57 0.00e+00 2222.00
IUUC-Mmu-063885 Mus musculus 93.10 0.00e+00 2399.00
IUUC-Mlu-067025 Myotis lucifugus 66.51 0.00e+00 1493.00
IUUC-Nle-069448 Nomascus leucogenys 84.61 0.00e+00 1203.00
IUUC-Opr-070441 Ochotona princeps 88.86 0.00e+00 2072.00
IUUC-Ont-071752 Oreochromis niloticus 72.24 0.00e+00 1800.00
IUUC-Oan-073390 Ornithorhynchus anatinus 87.18 0.00e+00 2155.00
IUUC-Ocu-073753 Oryctolagus cuniculus 92.62 0.00e+00 2999.00
IUUC-Ogu-078849 Oryza glumaepatula 41.67 2.00e-14 74.70
IUUC-Olo-080259 Oryza longistaminata 41.67 2.00e-14 75.10
IUUC-Ome-081199 Oryza meridionalis 41.67 2.00e-14 75.10
IUUC-Oni-082167 Oryza nivara 41.67 4.00e-14 73.90
IUUC-Oru-084541 Oryza rufipogon 41.67 4.00e-14 73.90
IUUC-Olu-087698 Ostreococcus lucimarinus 28.57 2.00e-16 81.30
IUUC-Oga-088602 Otolemur garnettii 94.77 0.00e+00 2388.00
IUUC-Ptr-091363 Pan troglodytes 95.96 0.00e+00 2430.00
IUUC-Pan-092385 Papio anubis 95.42 0.00e+00 2391.00
IUUC-Pfo-097486 Poecilia formosa 74.07 0.00e+00 1859.00
IUUC-Pab-098281 Pongo abelii 85.02 0.00e+00 2060.00
IUUC-Pca-100270 Procavia capensis 78.30 0.00e+00 1338.00
IUUC-Pva-102335 Pteropus vampyrus 92.31 0.00e+00 2333.00
IUUC-Rno-106122 Rattus norvegicus 92.25 0.00e+00 2357.00
IUUC-Sha-106851 Sarcophilus harrisii 91.59 0.00e+00 2251.00
IUUC-Sit-110414 Setaria italica 40.48 3.00e-14 74.30
IUUC-Sbi-114170 Sorghum bicolor 40.00 8.00e-15 76.30
IUUC-Tgu-117028 Taeniopygia guttata 90.35 0.00e+00 2308.00
IUUC-Tru-117789 Takifugu rubripes 75.71 0.00e+00 1866.00
IUUC-Tsy-119039 Tarsius syrichta 93.29 0.00e+00 1394.00
IUUC-Tni-119952 Tetraodon nigroviridis 73.60 0.00e+00 1728.00
IUUC-Tae-123242 Triticum aestivum 41.67 4.00e-14 74.30
IUUC-Tur-126623 Triticum urartu 41.67 4.00e-14 73.90
IUUC-Tbe-127754 Tupaia belangeri 84.70 0.00e+00 1740.00
IUUC-Ttr-129178 Tursiops truncatus 96.43 0.00e+00 2396.00
IUUC-Uma-129456 Ustilago maydis 31.66 2.00e-32 135.00
IUUC-Vpa-130687 Vicugna pacos 92.23 0.00e+00 1211.00
IUUC-Xtr-132905 Xenopus tropicalis 85.40 0.00e+00 2165.00
Created Date 25-Jun-2017

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