iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036895

Ensembl Protein ID

ENSFALP00000012084.1

UniProt Accession

U3KAN0; U3KAN0_FICAL

Genbank Protein ID

ENSFALP00000012084

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01021841

Gene Name

FZR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000011577.1	ENSFALT00000012133.1	ENSFALP00000012084.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	5.00e-151	501.8	175	479
E3 adaptor/Cullin RING/DCX/DWD	9.10e-27	91.7	311	341

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+kvldapel+ddfylnL+dWss nvl+v+Lg++vylwsa+t++v++l+dl  e+d+vtsv w+e+g+l+avGt+kg v+i+D+++ kk
   Q: 175  PFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLsVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKK 263
           689************************************************99************************************ PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelkl.stlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfk 176
           +++l+gh+arvgaL+Wna++lssGsrd++il+rd+r++ l+  ++lq+h+qevCGlkw++d++lLasGGnDn++ vw++ss +P+++++
   Q: 264  LSMLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPPLQSeRRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYT 352
           ******************************************99********************************************* PP
   S: 177  ehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkg 265
           eh aavkaiawsP+q++lLasGGGtaDrci+fwntltg+ l++idtgsqvc+l+wsk+++elvsthG+++n+i +wkypsl++va+l+g
   Q: 353  EHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTG 441
           ***************************************************************************************** PP
   S: 266  heaRvlslalspdgeaivtaagDetlrfwklfdkkkak 303
           h++Rvl+la+spdgeaivt+agDetlrfw++f+k++++
   Q: 442  HSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRST 479
           *********************************99875 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH  +v++l++ +d  ll+sG++D+++ vW+
   Q: 311  GHRQEVCGLKWsTDhQLLASGGNDNKLLVWN 341
           8**********98889**************9 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MDQDYERRLL RQINIQNENT MPCVAEMRRT LTPSNSPMSS PSKHGDRFIP SRAGANWSIN 60
FHRINENEKS PSQNRKAKDA TSDTGKDGLA YSALLKNELL GAGIEKVQDP QTEDRRLQPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACACTAGTT ACTGCTTGGA CTTTGCATAC ATAAATTCCT GAGCCGGCTG ATCTCTCCAG 60
CCAGCTTCCC ACCATGGATC AGGACTACGA GAGACGTCTC CTACGCCAAA TCAACATACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0031572--P:G2 DNA damage checkpoint
GO:0070306--P:lens fiber cell differentiation
GO:0090344--P:negative regulation of cell aging
GO:0008284--P:positive regulation of cell proliferation
GO:0045732--P:positive regulation of protein catabolic process
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0040020--P:regulation of meiotic nuclear division

KEGG

fab:101807726

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000670	Aegilops tauschii	64.19	2.00e-114	406.00
IUUC-Aml-002003	Ailuropoda melanoleuca	93.95	0.00e+00	929.00
IUUC-Atr-002753	Amborella trichopoda	57.40	1.00e-132	466.00
IUUC-Apl-003212	Anas platyrhynchos	99.80	0.00e+00	1018.00
IUUC-Aly-005442	Arabidopsis lyrata	57.34	2.00e-139	488.00
IUUC-Ath-006938	Arabidopsis thaliana	57.70	6.00e-138	483.00
IUUC-Ago-007784	Ashbya gossypii	49.42	2.00e-96	346.00
IUUC-Acl-008269	Aspergillus clavatus	50.00	2.00e-133	469.00
IUUC-Afl-008432	Aspergillus flavus	50.84	9.00e-133	466.00
IUUC-Afu-008829	Aspergillus fumigatus	50.82	2.00e-134	472.00
IUUC-Ani-009471	Aspergillus nidulans	50.00	2.00e-132	465.00
IUUC-Ang-009711	Aspergillus niger	51.06	5.00e-131	461.00
IUUC-Aor-010118	Aspergillus oryzae	50.84	9.00e-133	466.00
IUUC-Ate-010534	Aspergillus terreus	50.00	2.00e-132	466.00
IUUC-Ame-011011	Astyanax mexicanus	93.56	0.00e+00	892.00
IUUC-Bgr-012013	Blumeria graminis	50.71	1.00e-131	463.00
IUUC-Bta-012586	Bos taurus	98.38	0.00e+00	1007.00
IUUC-Bci-013807	Botrytis cinerea	51.85	2.00e-126	446.00
IUUC-Bdi-014981	Brachypodium distachyon	52.83	1.00e-129	456.00
IUUC-Bol-016301	Brassica oleracea	56.78	7.00e-138	483.00
IUUC-Bra-017453	Brassica rapa	56.78	5.00e-138	484.00
IUUC-Cel-018472	Caenorhabditis elegans	65.78	5.00e-144	504.00
IUUC-Cja-019929	Callithrix jacchus	97.38	0.00e+00	976.00
IUUC-Cfa-020977	Canis familiaris	97.58	0.00e+00	980.00
IUUC-Cpo-021537	Cavia porcellus	98.17	0.00e+00	1005.00
IUUC-Csa-023389	Chlorocebus sabaeus	97.77	0.00e+00	981.00
IUUC-Cin-025327	Ciona intestinalis	69.43	0.00e+00	628.00
IUUC-Csv-025921	Ciona savignyi	66.67	0.00e+00	666.00
IUUC-Cgl-026631	Colletotrichum gloeosporioides	51.73	5.00e-133	468.00
IUUC-Cne-026933	Cryptococcus neoformans	59.58	6.00e-128	451.00
IUUC-Cme-027143	Cyanidioschyzon merolae	63.70	3.00e-118	419.00
IUUC-Dre-027470	Danio rerio	92.14	0.00e+00	885.00
IUUC-Dno-029629	Dasypus novemcinctus	88.96	0.00e+00	799.00
IUUC-Dor-030187	Dipodomys ordii	86.90	0.00e+00	867.00
IUUC-Dse-031502	Dothistroma septosporum	50.43	4.00e-127	448.00
IUUC-Dme-031858	Drosophila melanogaster	75.11	0.00e+00	687.00
IUUC-Ete-032562	Echinops telfairi	85.40	0.00e+00	830.00
IUUC-Eca-034210	Equus caballus	97.97	0.00e+00	985.00
IUUC-Fca-035839	Felis catus	92.90	0.00e+00	929.00
IUUC-Fox-037814	Fusarium oxysporum	64.29	8.00e-124	436.00
IUUC-Fso-038420	Fusarium solani	50.31	6.00e-133	467.00
IUUC-Gmo-039544	Gadus morhua	90.14	0.00e+00	862.00
IUUC-Ggr-039774	Gaeumannomyces graminis	51.75	1.00e-132	466.00
IUUC-Gga-041025	Gallus gallus	99.59	0.00e+00	1016.00
IUUC-Gac-041596	Gasterosteus aculeatus	90.93	0.00e+00	874.00
IUUC-Gma-042657	Glycine max	53.81	2.00e-135	475.00
IUUC-Ggo-045599	Gorilla gorilla	96.98	0.00e+00	938.00
IUUC-Hsa-046695	Homo sapiens	97.18	0.00e+00	975.00
IUUC-Hvu-047486	Hordeum vulgare	65.95	9.00e-107	379.00
IUUC-Itr-048192	Ictidomys tridecemlineatus	97.16	0.00e+00	981.00
IUUC-Kpa-049239	Komagataella pastoris	58.50	3.00e-122	431.00
IUUC-Lch-049827	Latimeria chalumnae	97.16	0.00e+00	939.00
IUUC-Lpe-051568	Leersia perrieri	50.91	1.00e-111	396.00
IUUC-Loc-052856	Lepisosteus oculatus	95.76	0.00e+00	918.00
IUUC-Laf-054321	Loxodonta africana	62.70	2.00e-150	525.00
IUUC-Mcc-055601	Macaca mulatta	97.77	0.00e+00	981.00
IUUC-Meu-056276	Macropus eugenii	68.58	3.00e-170	590.00
IUUC-Mor-057113	Magnaporthe oryzae	51.34	8.00e-133	467.00
IUUC-Mpo-057599	Magnaporthe poae	51.64	1.00e-132	466.00
IUUC-Mtr-057689	Medicago truncatula	57.11	5.00e-137	480.00
IUUC-Mla-059048	Melampsora laricipopulina	50.10	3.00e-120	425.00
IUUC-Mga-060097	Meleagris gallopavo	93.56	0.00e+00	921.00
IUUC-Mvi-060465	Microbotryum violaceum	52.27	4.00e-131	461.00
IUUC-Mmr-061151	Microcebus murinus	88.51	0.00e+00	851.00
IUUC-Mdo-063062	Monodelphis domestica	99.39	0.00e+00	1017.00
IUUC-Mmu-063731	Mus musculus	97.77	0.00e+00	981.00
IUUC-Mac-065208	Musa acuminata	57.70	6.00e-130	457.00
IUUC-Mpu-066173	Mustela putorius furo	97.77	0.00e+00	981.00
IUUC-Mlu-068030	Myotis lucifugus	97.78	0.00e+00	980.00
IUUC-Nfi-068536	Neosartorya fischeri	50.82	7.00e-135	474.00
IUUC-Ncr-068734	Neurospora crassa	52.15	4.00e-135	474.00
IUUC-Nle-070163	Nomascus leucogenys	97.77	0.00e+00	982.00
IUUC-Opr-070974	Ochotona princeps	91.78	2.00e-155	541.00
IUUC-Ont-072507	Oreochromis niloticus	87.68	0.00e+00	887.00
IUUC-Oan-073634	Ornithorhynchus anatinus	99.66	2.00e-175	607.00
IUUC-Oba-075417	Oryza barthii	62.86	7.00e-111	394.00
IUUC-Obr-076123	Oryza brachyantha	69.51	3.00e-126	445.00
IUUC-Ogl-077294	Oryza glaberrima	52.81	3.00e-126	445.00
IUUC-Ogu-077996	Oryza glumaepatula	69.84	7.00e-125	440.00
IUUC-Oin-080172	Oryza indica	70.16	3.00e-126	444.00
IUUC-Olo-081068	Oryza longistaminata	70.16	4.00e-126	444.00
IUUC-Ome-081250	Oryza meridionalis	53.26	2.00e-127	448.00
IUUC-Oni-083048	Oryza nivara	52.81	3.00e-126	445.00
IUUC-Opu-083333	Oryza punctata	53.43	4.00e-127	447.00
IUUC-Oru-085001	Oryza rufipogon	52.81	3.00e-126	445.00
IUUC-Osa-086243	Oryza sativa	52.81	3.00e-126	445.00
IUUC-Ola-087094	Oryzias latipes	89.64	0.00e+00	832.00
IUUC-Oga-088911	Otolemur garnettii	98.38	0.00e+00	1006.00
IUUC-Oar-089508	Ovis aries	98.38	0.00e+00	1007.00
IUUC-Ptr-090967	Pan troglodytes	84.77	0.00e+00	649.00
IUUC-Pan-092147	Papio anubis	97.18	0.00e+00	975.00
IUUC-Psi-093702	Pelodiscus sinensis	98.99	0.00e+00	987.00
IUUC-Pma-094581	Petromyzon marinus	84.26	0.00e+00	803.00
IUUC-Pno-095139	Phaeosphaeria nodorum	59.76	6.00e-113	400.00
IUUC-Ppa-095952	Physcomitrella patens	57.88	3.00e-141	494.00
IUUC-Pfo-096309	Poecilia formosa	91.33	0.00e+00	877.00
IUUC-Pab-098762	Pongo abelii	79.84	0.00e+00	749.00
IUUC-Pop-098924	Populus trichocarpa	57.21	9.00e-133	466.00
IUUC-Pca-100565	Procavia capensis	92.39	0.00e+00	870.00
IUUC-Ppe-101924	Prunus persica	57.31	1.00e-136	479.00
IUUC-Pva-102602	Pteropus vampyrus	94.95	0.00e+00	934.00
IUUC-Pgr-103466	Puccinia graminis	50.86	1.00e-118	420.00
IUUC-Ptt-103888	Puccinia triticina	53.71	7.00e-108	384.00
IUUC-Pte-104097	Pyrenophora teres	49.12	1.00e-129	456.00
IUUC-Pyt-104445	Pyrenophora triticirepentis	45.40	6.00e-112	397.00
IUUC-Rno-105028	Rattus norvegicus	97.36	0.00e+00	976.00
IUUC-Sce-106240	Saccharomyces cerevisiae	38.92	1.00e-94	340.00
IUUC-Sha-107107	Sarcophilus harrisii	85.20	0.00e+00	832.00
IUUC-Sja-107900	Schizosaccharomyces japonicus	48.99	2.00e-115	409.00
IUUC-Spo-108056	Schizosaccharomyces pombe	48.96	5.00e-114	404.00
IUUC-Ssl-108391	Sclerotinia sclerotiorum	52.70	3.00e-129	455.00
IUUC-Smo-108878	Selaginella moellendorffii	59.28	4.00e-145	507.00
IUUC-Sit-110550	Setaria italica	55.15	3.00e-127	447.00
IUUC-Sly-111446	Solanum lycopersicum	56.95	2.00e-134	472.00
IUUC-Stu-112491	Solanum tuberosum	55.46	1.00e-133	469.00
IUUC-Sar-112962	Sorex araneus	80.15	2.00e-119	421.00
IUUC-Sbi-114489	Sorghum bicolor	54.59	2.00e-124	438.00
IUUC-Sre-115222	Sporisorium reilianum	47.83	2.00e-132	465.00
IUUC-Ssc-116171	Sus scrofa	98.38	0.00e+00	1007.00
IUUC-Tgu-116878	Taeniopygia guttata	88.42	0.00e+00	857.00
IUUC-Tru-118222	Takifugu rubripes	89.98	0.00e+00	865.00
IUUC-Tni-119863	Tetraodon nigroviridis	90.73	0.00e+00	866.00
IUUC-Tca-121599	Theobroma cacao	54.86	8.00e-134	470.00
IUUC-Tre-122249	Trichoderma reesei	51.74	3.00e-134	471.00
IUUC-Tvi-122675	Trichoderma virens	51.93	4.00e-134	471.00
IUUC-Tae-123028	Triticum aestivum	58.59	3.00e-126	444.00
IUUC-Tur-126545	Triticum urartu	59.94	6.00e-104	370.00
IUUC-Tme-127151	Tuber melanosporum	54.96	2.00e-146	512.00
IUUC-Tbe-128056	Tupaia belangeri	89.38	3.00e-168	583.00
IUUC-Ttr-129055	Tursiops truncatus	96.77	0.00e+00	965.00
IUUC-Uma-129555	Ustilago maydis	47.64	2.00e-131	462.00
IUUC-Vda-130027	Verticillium dahliae	48.85	3.00e-134	472.00
IUUC-Vvi-131749	Vitis vinifera	55.33	3.00e-134	471.00
IUUC-Xtr-132808	Xenopus tropicalis	92.70	0.00e+00	925.00
IUUC-Xma-133183	Xiphophorus maculatus	91.33	0.00e+00	877.00
IUUC-Yli-134584	Yarrowia lipolytica	62.10	5.00e-131	461.00
IUUC-Zma-135640	Zea mays	68.04	3.00e-125	441.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence