iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037307

Ensembl Protein ID

ENSFALP00000005240.1

UniProt Accession

U3JR36; U3JR36_FICAL

Genbank Protein ID

ENSFALP00000005240

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01001144

Gene Name

BRWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000005039.1	ENSFALT00000005265.1	ENSFALP00000005240.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-34	116.2	187	222
UBD/Beta-Prp	1.20e-52	178.6	291	546

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gH +sv+c+af  + +++ +GsdD+ +k+W+++ g+
   Q: 187  GHLSSVYCVAFdRTgHRIFTGSDDCLVKIWSTHNGR 222
           8**********955599**************98876 PP

UBD/Beta-Prp

   S: 24   llatgsrdgtikvwdvttgkl......lrslsgheaevt..avkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlslsf 102
           +++++++dgt+  w+++t ++      ++  ++  ++v+  + +fs  g +l+tgs+D++i+ +    +t++ +  l+ h d+v s++f
   Q: 291  YMVSTGADGTVCFWQWDTDSMkfntkpVKFTEKPRPGVQmlCSSFSVGGMFLATGSTDHVIRMYffGSETPEKIAELESHADKVDSIQF 379
           8999*************988877877666667777777722556888888**************9999********************* PP
   S: 103  spsgdklvsGshdrtirvwdletgqclee...............tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtlt 176
           s  gd+++sGs+d t+r+w  e+ ++ +                 ++  +  v+++++++++n++v++ ++  +++W+++tg+ll++l 
   Q: 380  SNGGDRFISGSRDGTARIWRFEQAEWRSIlldmsdrllgdtcaeEDKFMKPKVTMIAWNQNDNYVVTAVNNHLLKVWNSSTGQLLHDLV 468
           **99**********************9999**********8887777777789************************************ PP
   S: 177  gghtdsvyslsfdsng.kelvsgsldgtvklwdlqtgec......vrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           g h d v  l+ ++   + ++s+++dg v +wd+ +g+       + + +gh   v + +fsp++++++++ s+g + i+
   Q: 469  G-HADEVFVLETHPFDcRIMLSAGHDGNVFIWDITKGTKtkhyfnMIEGQGH-GAVFDCKFSPDGQHFACTDSHGHLLIF 546
           9.*********76655499****************77763344433334444.566678999********9999988875 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MAEPAASSSS GASLPLIESE LYFLIARFLS TGPCRRALKV LVQELEQHQL LPKRLDWQGN 60
EHYRSYEELV LSNKHVAPDH LLQICKRIGP ILDKEIPPSI SRVNSLLGAG RQSLLRTAKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCA 60
GCGGGGGGGC GGCCGTGAGG GGAGGGAGGA AGGGGAGGGG AGGCGCTGAC AGCGCCGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

KEGG

fab:101807288

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001113	Aegilops tauschii	30.58	2.00e-65	244.00
IUUC-Aml-002332	Ailuropoda melanoleuca	77.72	0.00e+00	2230.00
IUUC-Apl-004083	Anas platyrhynchos	76.44	0.00e+00	2986.00
IUUC-Aca-004348	Anolis carolinensis	72.39	0.00e+00	2155.00
IUUC-Aly-006517	Arabidopsis lyrata	30.82	3.00e-75	277.00
IUUC-Ath-006577	Arabidopsis thaliana	30.03	5.00e-74	273.00
IUUC-Ame-010718	Astyanax mexicanus	70.71	0.00e+00	1203.00
IUUC-Bdi-014797	Brachypodium distachyon	29.59	2.00e-61	231.00
IUUC-Bol-015737	Brassica oleracea	30.03	5.00e-72	266.00
IUUC-Bra-017829	Brassica rapa	31.30	3.00e-72	267.00
IUUC-Cja-019966	Callithrix jacchus	72.42	0.00e+00	2345.00
IUUC-Cpo-021934	Cavia porcellus	77.35	0.00e+00	2301.00
IUUC-Cre-023003	Chlamydomonas reinhardtii	33.45	2.00e-33	137.00
IUUC-Csa-023352	Chlorocebus sabaeus	76.58	0.00e+00	2076.00
IUUC-Cho-024690	Choloepus hoffmanni	74.90	0.00e+00	813.00
IUUC-Csv-025813	Ciona savignyi	43.35	0.00e+00	635.00
IUUC-Dme-031752	Drosophila melanogaster	51.46	0.00e+00	689.00
IUUC-Gga-040865	Gallus gallus	83.19	0.00e+00	3326.00
IUUC-Gma-043340	Glycine max	30.51	8.00e-72	266.00
IUUC-Ggo-045500	Gorilla gorilla	77.42	0.00e+00	2283.00
IUUC-Hsa-046350	Homo sapiens	70.23	0.00e+00	2357.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	74.16	0.00e+00	903.00
IUUC-Lch-050646	Latimeria chalumnae	60.18	0.00e+00	1786.00
IUUC-Lpe-051619	Leersia perrieri	30.36	4.00e-72	267.00
IUUC-Loc-052853	Lepisosteus oculatus	66.29	0.00e+00	1886.00
IUUC-Laf-053848	Loxodonta africana	77.17	0.00e+00	2253.00
IUUC-Mcc-054638	Macaca mulatta	77.45	0.00e+00	2297.00
IUUC-Meu-056739	Macropus eugenii	75.55	0.00e+00	1063.00
IUUC-Mtr-058094	Medicago truncatula	30.70	2.00e-73	271.00
IUUC-Mga-060165	Meleagris gallopavo	88.04	0.00e+00	3010.00
IUUC-Mmr-061227	Microcebus murinus	71.02	0.00e+00	2397.00
IUUC-Mdo-062074	Monodelphis domestica	76.89	0.00e+00	2253.00
IUUC-Mmu-064075	Mus musculus	68.62	0.00e+00	2363.00
IUUC-Mac-065343	Musa acuminata	30.65	9.00e-77	282.00
IUUC-Nle-069402	Nomascus leucogenys	77.79	0.00e+00	2275.00
IUUC-Ont-072298	Oreochromis niloticus	61.87	0.00e+00	1867.00
IUUC-Oan-072954	Ornithorhynchus anatinus	69.99	0.00e+00	2488.00
IUUC-Ocu-074456	Oryctolagus cuniculus	70.02	0.00e+00	2373.00
IUUC-Oba-075709	Oryza barthii	28.32	4.00e-62	233.00
IUUC-Obr-076619	Oryza brachyantha	29.65	1.00e-70	262.00
IUUC-Ogu-078641	Oryza glumaepatula	38.59	1.00e-29	125.00
IUUC-Opu-083233	Oryza punctata	29.65	4.00e-66	247.00
IUUC-Oru-085195	Oryza rufipogon	28.32	5.00e-62	233.00
IUUC-Olu-087745	Ostreococcus lucimarinus	28.38	2.00e-53	204.00
IUUC-Oga-087938	Otolemur garnettii	63.97	0.00e+00	2079.00
IUUC-Ptr-091213	Pan troglodytes	77.38	0.00e+00	2287.00
IUUC-Pan-092444	Papio anubis	77.19	0.00e+00	2290.00
IUUC-Psi-093271	Pelodiscus sinensis	71.03	0.00e+00	2597.00
IUUC-Pma-094427	Petromyzon marinus	65.74	4.00e-130	457.00
IUUC-Ppa-095793	Physcomitrella patens	29.30	1.00e-74	275.00
IUUC-Pfo-097318	Poecilia formosa	62.70	0.00e+00	1802.00
IUUC-Pab-097573	Pongo abelii	76.10	0.00e+00	2214.00
IUUC-Pop-099672	Populus trichocarpa	31.07	2.00e-75	278.00
IUUC-Ppe-101849	Prunus persica	30.18	8.00e-76	279.00
IUUC-Rno-105687	Rattus norvegicus	60.69	0.00e+00	2324.00
IUUC-Sly-111348	Solanum lycopersicum	30.17	3.00e-76	280.00
IUUC-Sbi-114195	Sorghum bicolor	28.25	9.00e-61	228.00
IUUC-Tgu-116513	Taeniopygia guttata	93.63	0.00e+00	3816.00
IUUC-Tru-117625	Takifugu rubripes	59.22	0.00e+00	1681.00
IUUC-Tsy-118921	Tarsius syrichta	75.38	0.00e+00	1720.00
IUUC-Tni-120716	Tetraodon nigroviridis	58.48	0.00e+00	1678.00
IUUC-Tca-121615	Theobroma cacao	30.67	2.00e-70	261.00
IUUC-Tae-125478	Triticum aestivum	30.35	1.00e-72	268.00
IUUC-Tur-126809	Triticum urartu	30.17	4.00e-70	260.00
IUUC-Vpa-130444	Vicugna pacos	74.44	0.00e+00	2022.00
IUUC-Vvi-131332	Vitis vinifera	30.88	9.00e-77	282.00
IUUC-Xma-133633	Xiphophorus maculatus	65.14	0.00e+00	1142.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence