iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090637

UUCD1 version

UUC-PaT-00062

Ensembl Protein ID

ENSPTRP00000009271.2

UniProt Accession

G2HEK6; G2HEK6_PANTR

Genbank Protein ID

BAK62164.1; JAA01294.1; JAA16964.1; JAA30813.1; JAA34551.1

Protein Name

BRCA1 associated protein; BRCA1-associated protein

Genbank Nucleotide ID

AACZ03086842; GABC01010044; GABF01005181; GABD01002287; GABE01010188

Gene Name

BRAP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000005461.3	ENSPTRT00000010025.2	ENSPTRP00000009271.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.00e-07	30.1	264	304
UBD/ZnF/ZnF_UBP	1.40e-24	86.1	316	376

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg...plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C +Cle++++     l++ C+H fh +Clq+w           +CP+Cr
   Q: 264  CTVCLERMDESvngILTTLCNHSFHSQCLQRW--------DDTTCPVCR 304
           9*******77333366777*************........8889****8 PP

UBD/ZnF/ZnF_UBP

   S: 2    kcsvcdktenlWlcLtcgsvgCGRyvegHalkHyeetqhplvlslstlsvycYacddyvhr 62
           kc +c+ +enlW+cL+cg++gCGRyv+ Ha kH+eetqh ++++l + +v++Ya+d+yvhr
   Q: 316  KCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNYVHR 376
           8**********************************************************96 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MSVSLVVIRL ELAEHSPVPA GFGFSAAAGE MSDEEIKKTT LASAVACLEG KSPGEKVAII 60
HQHLGRREMT DVIIETMKSN PDELKTTVEE RKSSEASPTA QRSKDHSKEC INAAPDSPSK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTGGCTCCG AGGGCTGTTC GAGGAGCTGC TGCTGCTGAG GCGGCGGCAA CTGCATTGAG 60
GCGGTGGCGG CGCTGCCGGC CCCGGGCCGC TCGGCCTCTC GGCTCGCCTT CCAGCCTCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011422--BRAP2
IPR012677--Nucleotide-bd_a/b_plait
IPR000504--RRM_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50089--ZF_RING_2
PS50271--ZF_UBP

Pfam

PF07576--BRAP2
PF13639--zf-RING_2
PF02148--zf-UBP

SMART

SM00184--RING
SM00290--ZnF_UBP

Gene Ontology

GO:0005829--C:cytosol
GO:0031965--C:nuclear membrane
GO:0000151--C:ubiquitin ligase complex
GO:0008139--F:nuclear localization sequence binding
GO:0003676--F:nucleic acid binding
GO:0000166--F:nucleotide binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0000165--P:MAPK cascade
GO:0009968--P:negative regulation of signal transduction
GO:0007265--P:Ras protein signal transduction

KEGG

ptr:452249

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000519	Aegilops tauschii	30.72	1.00e-52	201.00
IUUC-Aml-002229	Ailuropoda melanoleuca	96.28	0.00e+00	1129.00
IUUC-Atr-002785	Amborella trichopoda	38.63	1.00e-91	330.00
IUUC-Apl-004048	Anas platyrhynchos	91.38	0.00e+00	927.00
IUUC-Aca-005133	Anolis carolinensis	85.01	0.00e+00	946.00
IUUC-Aly-006306	Arabidopsis lyrata	38.81	4.00e-77	281.00
IUUC-Ath-007604	Arabidopsis thaliana	35.04	2.00e-80	292.00
IUUC-Ago-007905	Ashbya gossypii	36.20	4.00e-70	258.00
IUUC-Acl-008310	Aspergillus clavatus	32.14	5.00e-66	245.00
IUUC-Afl-008497	Aspergillus flavus	31.71	9.00e-61	227.00
IUUC-Afu-008830	Aspergillus fumigatus	31.22	1.00e-63	237.00
IUUC-Ani-009485	Aspergillus nidulans	31.51	5.00e-67	248.00
IUUC-Ang-009603	Aspergillus niger	37.53	1.00e-64	240.00
IUUC-Aor-009935	Aspergillus oryzae	32.16	1.00e-64	241.00
IUUC-Ate-010485	Aspergillus terreus	31.98	3.00e-68	252.00
IUUC-Ame-011516	Astyanax mexicanus	85.17	0.00e+00	748.00
IUUC-Bgr-011985	Blumeria graminis	27.15	1.00e-45	178.00
IUUC-Bta-013203	Bos taurus	96.82	0.00e+00	1144.00
IUUC-Bci-013788	Botrytis cinerea	33.53	7.00e-53	202.00
IUUC-Bdi-014763	Brachypodium distachyon	35.58	1.00e-81	296.00
IUUC-Bol-015518	Brassica oleracea	34.41	8.00e-78	285.00
IUUC-Bra-017435	Brassica rapa	35.37	4.00e-78	285.00
IUUC-Cel-018194	Caenorhabditis elegans	36.99	1.00e-109	390.00
IUUC-Cja-018948	Callithrix jacchus	98.38	0.00e+00	1123.00
IUUC-Cfa-020377	Canis familiaris	97.47	0.00e+00	1175.00
IUUC-Cpo-021930	Cavia porcellus	94.52	0.00e+00	1093.00
IUUC-Cre-022571	Chlamydomonas reinhardtii	42.35	4.00e-58	217.00
IUUC-Csa-023554	Chlorocebus sabaeus	98.73	0.00e+00	986.00
IUUC-Cho-025045	Choloepus hoffmanni	93.17	2.00e-138	485.00
IUUC-Cin-025326	Ciona intestinalis	43.42	8.00e-112	397.00
IUUC-Csv-026232	Ciona savignyi	43.88	2.00e-114	405.00
IUUC-Cgl-026587	Colletotrichum gloeosporioides	30.69	2.00e-59	224.00
IUUC-Cne-026980	Cryptococcus neoformans	35.59	3.00e-50	192.00
IUUC-Cme-027262	Cyanidioschyzon merolae	35.10	1.00e-60	228.00
IUUC-Dre-028521	Danio rerio	77.27	0.00e+00	911.00
IUUC-Dno-029291	Dasypus novemcinctus	95.95	0.00e+00	1120.00
IUUC-Dor-030231	Dipodomys ordii	86.82	0.00e+00	1021.00
IUUC-Dse-031234	Dothistroma septosporum	32.54	5.00e-56	212.00
IUUC-Dme-032095	Drosophila melanogaster	44.13	1.00e-120	426.00
IUUC-Ete-032227	Echinops telfairi	83.51	0.00e+00	637.00
IUUC-Eca-034404	Equus caballus	97.17	0.00e+00	1155.00
IUUC-Eeu-035030	Erinaceus europaeus	77.93	3.00e-133	468.00
IUUC-Fca-035428	Felis catus	97.35	0.00e+00	1146.00
IUUC-Fal-037435	Ficedula albicollis	91.15	0.00e+00	975.00
IUUC-Fox-037733	Fusarium oxysporum	32.29	1.00e-60	227.00
IUUC-Fso-038427	Fusarium solani	32.87	5.00e-60	225.00
IUUC-Gmo-038817	Gadus morhua	75.04	0.00e+00	853.00
IUUC-Ggr-039949	Gaeumannomyces graminis	28.77	2.00e-55	210.00
IUUC-Gga-040929	Gallus gallus	89.71	0.00e+00	991.00
IUUC-Gac-041893	Gasterosteus aculeatus	75.80	0.00e+00	883.00
IUUC-Gma-043119	Glycine max	35.70	2.00e-82	299.00
IUUC-Ggo-045106	Gorilla gorilla	99.32	0.00e+00	925.00
IUUC-Hsa-045685	Homo sapiens	99.83	0.00e+00	1202.00
IUUC-Hvu-047475	Hordeum vulgare	33.58	4.00e-35	141.00
IUUC-Itr-048406	Ictidomys tridecemlineatus	95.94	0.00e+00	1108.00
IUUC-Kpa-049175	Komagataella pastoris	35.46	8.00e-65	241.00
IUUC-Lch-050408	Latimeria chalumnae	81.26	0.00e+00	992.00
IUUC-Lpe-050777	Leersia perrieri	31.26	6.00e-70	258.00
IUUC-Loc-052160	Lepisosteus oculatus	66.90	0.00e+00	727.00
IUUC-Lma-053095	Leptosphaeria maculans	34.43	2.00e-78	286.00
IUUC-Laf-053497	Loxodonta africana	95.29	0.00e+00	1147.00
IUUC-Mcc-055381	Macaca mulatta	99.29	0.00e+00	1178.00
IUUC-Meu-056402	Macropus eugenii	71.37	0.00e+00	675.00
IUUC-Mor-057002	Magnaporthe oryzae	30.12	1.00e-60	227.00
IUUC-Mpo-057508	Magnaporthe poae	26.52	1.00e-53	204.00
IUUC-Mtr-058619	Medicago truncatula	35.31	3.00e-69	255.00
IUUC-Mla-058901	Melampsora laricipopulina	34.20	2.00e-72	267.00
IUUC-Mga-059667	Meleagris gallopavo	95.37	0.00e+00	917.00
IUUC-Mvi-060229	Microbotryum violaceum	29.48	2.00e-63	237.00
IUUC-Mmr-060881	Microcebus murinus	86.93	0.00e+00	972.00
IUUC-Mdo-062573	Monodelphis domestica	91.74	0.00e+00	998.00
IUUC-Mmu-063656	Mus musculus	91.05	0.00e+00	1092.00
IUUC-Mac-065512	Musa acuminata	37.34	8.00e-82	297.00
IUUC-Mpu-065816	Mustela putorius furo	97.35	0.00e+00	1152.00
IUUC-Mlu-067225	Myotis lucifugus	95.76	0.00e+00	1153.00
IUUC-Nfi-068534	Neosartorya fischeri	31.88	9.00e-65	241.00
IUUC-Ncr-068801	Neurospora crassa	27.99	1.00e-58	221.00
IUUC-Nle-069258	Nomascus leucogenys	99.42	0.00e+00	1087.00
IUUC-Opr-070877	Ochotona princeps	81.63	0.00e+00	909.00
IUUC-Ont-072141	Oreochromis niloticus	76.27	0.00e+00	885.00
IUUC-Oan-072961	Ornithorhynchus anatinus	91.58	0.00e+00	1039.00
IUUC-Ocu-074020	Oryctolagus cuniculus	94.49	0.00e+00	959.00
IUUC-Oba-075084	Oryza barthii	31.47	2.00e-70	259.00
IUUC-Obr-076840	Oryza brachyantha	36.05	4.00e-80	291.00
IUUC-Ogl-077880	Oryza glaberrima	42.38	3.00e-79	288.00
IUUC-Ogu-078968	Oryza glumaepatula	31.47	1.00e-70	260.00
IUUC-Oin-079200	Oryza indica	42.38	3.00e-79	289.00
IUUC-Olo-080753	Oryza longistaminata	34.59	1.00e-61	229.00
IUUC-Ome-081756	Oryza meridionalis	31.47	2.00e-70	259.00
IUUC-Oni-082434	Oryza nivara	31.47	2.00e-70	259.00
IUUC-Opu-083262	Oryza punctata	31.67	6.00e-69	254.00
IUUC-Oru-084381	Oryza rufipogon	31.47	1.00e-70	260.00
IUUC-Osa-085760	Oryza sativa	47.94	1.00e-71	262.00
IUUC-Ola-087390	Oryzias latipes	74.06	0.00e+00	830.00
IUUC-Olu-087694	Ostreococcus lucimarinus	31.83	8.00e-59	221.00
IUUC-Oga-088612	Otolemur garnettii	97.17	0.00e+00	1125.00
IUUC-Oar-089988	Ovis aries	96.64	0.00e+00	1139.00
IUUC-Pan-092506	Papio anubis	99.12	0.00e+00	1175.00
IUUC-Psi-093026	Pelodiscus sinensis	90.02	0.00e+00	955.00
IUUC-Pno-094779	Phaeosphaeria nodorum	31.93	4.00e-57	215.00
IUUC-Ppa-095731	Physcomitrella patens	40.22	3.00e-95	342.00
IUUC-Pfo-096725	Poecilia formosa	77.21	0.00e+00	863.00
IUUC-Pab-098413	Pongo abelii	99.48	0.00e+00	770.00
IUUC-Pop-099538	Populus trichocarpa	37.87	7.00e-82	297.00
IUUC-Pca-100130	Procavia capensis	83.22	0.00e+00	971.00
IUUC-Ppe-101843	Prunus persica	37.58	8.00e-87	314.00
IUUC-Pva-102752	Pteropus vampyrus	92.23	0.00e+00	1080.00
IUUC-Pgr-103478	Puccinia graminis	38.89	1.00e-76	280.00
IUUC-Ptt-103921	Puccinia triticina	38.33	5.00e-71	262.00
IUUC-Pte-104032	Pyrenophora teres	34.11	5.00e-75	275.00
IUUC-Pyt-104480	Pyrenophora triticirepentis	32.90	4.00e-73	269.00
IUUC-Rno-106037	Rattus norvegicus	76.14	0.00e+00	883.00
IUUC-Sce-106310	Saccharomyces cerevisiae	31.18	2.00e-60	226.00
IUUC-Sha-106752	Sarcophilus harrisii	89.53	0.00e+00	1036.00
IUUC-Sja-107665	Schizosaccharomyces japonicus	37.09	2.00e-82	299.00
IUUC-Spo-108042	Schizosaccharomyces pombe	34.17	6.00e-73	268.00
IUUC-Ssl-108504	Sclerotinia sclerotiorum	30.26	7.00e-53	202.00
IUUC-Smo-109399	Selaginella moellendorffii	38.19	5.00e-90	324.00
IUUC-Sit-110251	Setaria italica	38.70	2.00e-88	319.00
IUUC-Sly-111563	Solanum lycopersicum	37.78	2.00e-77	283.00
IUUC-Stu-112294	Solanum tuberosum	38.27	6.00e-81	294.00
IUUC-Sar-113080	Sorex araneus	79.62	2.00e-149	521.00
IUUC-Sbi-113915	Sorghum bicolor	38.51	3.00e-85	308.00
IUUC-Sre-114897	Sporisorium reilianum	36.21	1.00e-58	221.00
IUUC-Ssc-115369	Sus scrofa	98.91	7.00e-113	399.00
IUUC-Tgu-116710	Taeniopygia guttata	87.81	0.00e+00	1027.00
IUUC-Tru-117941	Takifugu rubripes	76.06	0.00e+00	866.00
IUUC-Tsy-118902	Tarsius syrichta	82.49	2.00e-105	375.00
IUUC-Tni-120587	Tetraodon nigroviridis	75.62	0.00e+00	901.00
IUUC-Tca-121425	Theobroma cacao	38.08	3.00e-89	322.00
IUUC-Tre-121874	Trichoderma reesei	30.17	2.00e-59	223.00
IUUC-Tvi-122266	Trichoderma virens	36.39	4.00e-60	226.00
IUUC-Tae-123517	Triticum aestivum	35.70	2.00e-80	292.00
IUUC-Tur-126467	Triticum urartu	32.86	1.00e-52	200.00
IUUC-Tme-127096	Tuber melanosporum	36.26	8.00e-60	224.00
IUUC-Tbe-128012	Tupaia belangeri	90.06	0.00e+00	900.00
IUUC-Ttr-128388	Tursiops truncatus	97.00	0.00e+00	1152.00
IUUC-Uma-129610	Ustilago maydis	33.93	3.00e-56	213.00
IUUC-Vda-129830	Verticillium dahliae	29.16	1.00e-56	214.00
IUUC-Vpa-130171	Vicugna pacos	96.79	0.00e+00	1168.00
IUUC-Vvi-131063	Vitis vinifera	42.26	4.00e-82	298.00
IUUC-Xtr-132313	Xenopus tropicalis	82.09	0.00e+00	1004.00
IUUC-Xma-133303	Xiphophorus maculatus	76.19	0.00e+00	855.00
IUUC-Yli-134669	Yarrowia lipolytica	31.73	3.00e-64	239.00
IUUC-Zma-135783	Zea mays	37.39	8.00e-83	300.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence