iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005320

UUCD1 version

UUC-AnC-00454

Ensembl Protein ID

ENSACAP00000000374.2

UniProt Accession

G1K8H7; G1K8H7_ANOCA

Protein Name

Uncharacterized protein

Gene Name

SPOPL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000000338.3	ENSACAT00000000389.3	ENSACAP00000000374.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.60e-30	105.2	200	266
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.00e-08	34.4	299	326

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +D+ ++vgg+ef+ahk+vLaa+S+vF+a+f++e+eesk k++vei+dv+pevf+++++F+Ytgk+++ 
   Q: 200  TDCSFNVGGQEFKAHKSVLAARSPVFNAMFEHEMEESK-KNRVEISDVDPEVFKEMMRFIYTGKASNL 266
           7*************************************.*************************9875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfil 28
           +eN+++il +Adl+++++Lk +a+dfi+
   Q: 299  VENVAEILILADLHSAEQLKAQAIDFIN 326
           79*************************7 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSRAATPPPS GEMSSGPIAE SWCYTQVKVV KFSYMWTINN FSFCREEMGE VLKSSTFSSG 60
PNDKMKWCLR VNPKGLDDES KDYLSLYLLL VSCPKSEVRA KFKFSLLNAK REETKAMESQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAAGGCCC ACATTTGCCC ATGCCTGGAC TAAACTGTAA TAGCGGTGTG TTCCCCTTTA 60
ACTGCGATGG CGGCATCCTC TTGCATTCTG GGGCTTGTAG TTCGCGGAGG CCCAAGCGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR002083--MATH/TRAF_dom
IPR011333--SKP1/BTB/POZ
IPR034089--SPOP_C
IPR008974--TRAF-like

PROSITE

PS50097--BTB
PS50144--MATH

Pfam

PF00651--BTB
PF00917--MATH

SMART

SM00225--BTB
SM00061--MATH

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0031397--P:negative regulation of protein ubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030162--P:regulation of proteolysis

KEGG

acs:100567891

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000119	Aegilops tauschii	33.53	2.00e-40	159.00
IUUC-Aml-001309	Ailuropoda melanoleuca	92.60	0.00e+00	716.00
IUUC-Atr-002922	Amborella trichopoda	28.73	2.00e-40	159.00
IUUC-Apl-003864	Anas platyrhynchos	95.66	0.00e+00	759.00
IUUC-Ame-011843	Astyanax mexicanus	90.05	0.00e+00	722.00
IUUC-Bta-013528	Bos taurus	88.78	0.00e+00	676.00
IUUC-Bdi-014743	Brachypodium distachyon	32.68	5.00e-44	171.00
IUUC-Bol-015218	Brassica oleracea	31.44	3.00e-43	169.00
IUUC-Bra-016833	Brassica rapa	30.91	6.00e-43	167.00
IUUC-Cja-019227	Callithrix jacchus	90.05	0.00e+00	714.00
IUUC-Cfa-020990	Canis familiaris	92.60	0.00e+00	717.00
IUUC-Cpo-021660	Cavia porcellus	93.37	0.00e+00	739.00
IUUC-Csa-023569	Chlorocebus sabaeus	90.28	2.00e-150	524.00
IUUC-Cho-024732	Choloepus hoffmanni	83.42	0.00e+00	642.00
IUUC-Cin-025636	Ciona intestinalis	74.04	6.00e-160	556.00
IUUC-Dre-027880	Danio rerio	91.58	0.00e+00	727.00
IUUC-Dno-029399	Dasypus novemcinctus	92.86	0.00e+00	735.00
IUUC-Ete-032759	Echinops telfairi	86.48	0.00e+00	677.00
IUUC-Eca-033858	Equus caballus	92.86	0.00e+00	719.00
IUUC-Eeu-035156	Erinaceus europaeus	93.85	2.00e-175	607.00
IUUC-Fca-036500	Felis catus	93.11	0.00e+00	719.00
IUUC-Fal-037023	Ficedula albicollis	95.66	0.00e+00	759.00
IUUC-Gmo-038605	Gadus morhua	91.58	0.00e+00	728.00
IUUC-Ggr-039747	Gaeumannomyces graminis	26.67	1.00e-08	53.50
IUUC-Gga-040204	Gallus gallus	95.66	0.00e+00	759.00
IUUC-Gac-042260	Gasterosteus aculeatus	91.84	0.00e+00	730.00
IUUC-Gma-043055	Glycine max	29.54	6.00e-41	161.00
IUUC-Ggo-045160	Gorilla gorilla	92.60	0.00e+00	735.00
IUUC-Hsa-045729	Homo sapiens	92.86	0.00e+00	737.00
IUUC-Itr-048153	Ictidomys tridecemlineatus	92.60	0.00e+00	736.00
IUUC-Lch-050036	Latimeria chalumnae	91.07	0.00e+00	700.00
IUUC-Lpe-050805	Leersia perrieri	31.04	5.00e-44	171.00
IUUC-Loc-052332	Lepisosteus oculatus	90.73	0.00e+00	724.00
IUUC-Lma-053180	Leptosphaeria maculans	27.05	4.00e-07	49.30
IUUC-Laf-053691	Loxodonta africana	92.35	0.00e+00	734.00
IUUC-Mcc-055808	Macaca mulatta	92.60	0.00e+00	735.00
IUUC-Mpo-057466	Magnaporthe poae	30.00	2.00e-08	52.00
IUUC-Mga-059990	Meleagris gallopavo	95.66	0.00e+00	759.00
IUUC-Mmr-061748	Microcebus murinus	93.11	0.00e+00	739.00
IUUC-Mdo-062472	Monodelphis domestica	89.42	0.00e+00	672.00
IUUC-Mmu-063522	Mus musculus	90.82	0.00e+00	723.00
IUUC-Mac-064762	Musa acuminata	32.63	2.00e-33	135.00
IUUC-Mpu-065894	Mustela putorius furo	86.81	0.00e+00	698.00
IUUC-Mlu-067879	Myotis lucifugus	91.84	0.00e+00	711.00
IUUC-Nle-069115	Nomascus leucogenys	92.86	0.00e+00	737.00
IUUC-Ont-072569	Oreochromis niloticus	91.58	0.00e+00	728.00
IUUC-Oan-073449	Ornithorhynchus anatinus	91.84	0.00e+00	724.00
IUUC-Ocu-073817	Oryctolagus cuniculus	92.86	0.00e+00	738.00
IUUC-Oba-075042	Oryza barthii	33.04	3.00e-43	170.00
IUUC-Obr-076906	Oryza brachyantha	33.43	6.00e-39	154.00
IUUC-Ogl-077426	Oryza glaberrima	33.04	1.00e-43	169.00
IUUC-Ogu-078752	Oryza glumaepatula	34.77	9.00e-40	158.00
IUUC-Oin-079531	Oryza indica	33.63	8.00e-43	167.00
IUUC-Olo-080583	Oryza longistaminata	32.24	3.00e-41	162.00
IUUC-Ome-081184	Oryza meridionalis	33.14	2.00e-39	157.00
IUUC-Oni-082862	Oryza nivara	33.24	4.00e-43	169.00
IUUC-Opu-083557	Oryza punctata	32.43	4.00e-37	148.00
IUUC-Oru-084424	Oryza rufipogon	32.25	8.00e-42	164.00
IUUC-Osa-085702	Oryza sativa	33.04	2.00e-41	162.00
IUUC-Ola-086485	Oryzias latipes	90.08	0.00e+00	716.00
IUUC-Oga-087982	Otolemur garnettii	87.76	0.00e+00	686.00
IUUC-Oar-089667	Ovis aries	93.11	0.00e+00	719.00
IUUC-Ptr-090729	Pan troglodytes	92.86	0.00e+00	737.00
IUUC-Pan-091988	Papio anubis	92.35	0.00e+00	734.00
IUUC-Psi-093103	Pelodiscus sinensis	95.92	0.00e+00	761.00
IUUC-Pno-095092	Phaeosphaeria nodorum	23.35	1.00e-05	46.60
IUUC-Pfo-096279	Poecilia formosa	82.95	0.00e+00	637.00
IUUC-Pab-098431	Pongo abelii	92.86	0.00e+00	737.00
IUUC-Pop-099525	Populus trichocarpa	31.00	5.00e-31	128.00
IUUC-Pca-100373	Procavia capensis	74.15	7.00e-129	452.00
IUUC-Ppe-101816	Prunus persica	30.73	9.00e-37	147.00
IUUC-Pva-102660	Pteropus vampyrus	92.86	0.00e+00	718.00
IUUC-Pte-104298	Pyrenophora teres	24.66	2.00e-06	47.40
IUUC-Rno-105020	Rattus norvegicus	83.25	0.00e+00	676.00
IUUC-Sha-107038	Sarcophilus harrisii	93.62	0.00e+00	741.00
IUUC-Sit-110155	Setaria italica	34.75	2.00e-39	156.00
IUUC-Sbi-114704	Sorghum bicolor	35.06	8.00e-42	164.00
IUUC-Ssc-116199	Sus scrofa	88.78	0.00e+00	677.00
IUUC-Tgu-116755	Taeniopygia guttata	95.15	0.00e+00	750.00
IUUC-Tru-118288	Takifugu rubripes	87.76	0.00e+00	701.00
IUUC-Tni-119955	Tetraodon nigroviridis	88.58	0.00e+00	708.00
IUUC-Tre-122160	Trichoderma reesei	32.88	4.00e-09	55.10
IUUC-Tvi-122498	Trichoderma virens	31.19	4.00e-11	61.60
IUUC-Tae-124643	Triticum aestivum	36.94	6.00e-42	164.00
IUUC-Tur-126285	Triticum urartu	36.94	4.00e-42	164.00
IUUC-Ttr-129261	Tursiops truncatus	92.60	0.00e+00	716.00
IUUC-Vda-129835	Verticillium dahliae	37.74	7.00e-08	52.40
IUUC-Vpa-130728	Vicugna pacos	93.51	5.00e-180	622.00
IUUC-Xtr-132576	Xenopus tropicalis	87.70	3.00e-177	613.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence