iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003311

Ensembl Protein ID

ENSAPLP00000003226.1

UniProt Accession

U3I7K5; U3I7K5_ANAPL

Genbank Protein ID

ENSAPLP00000003226

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

ADON01136586

Gene Name

KMT2C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000003614.1	ENSAPLT00000003825.1	ENSAPLP00000003226.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	7.30e-29	99.5	1040	1091

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCr 52
            C++C ++++de+ +++C++C++w+H+ C +l+ eee++n  +  + C+ Cr
   Q: 1040 TCPICYRTYRDEELIIQCRQCDRWMHAICQNLNTEEEVENIADmgFDCTICR 1091
           6***************************************99999******8 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

RPRSRGKTAV EDEDSMDGLE AAETENTVET EVKEQSAEED AQAEVDSTKQ LTPVLQRSVS 60
EESASSTASV GVEAKTSEQL CAFCYCGERS SLGQGDLKQF SPTPGYVIPW KNQPLNKSEA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGCCTCGGA GTAGAGGAAA AACTGCAGTG GAGGATGAAG ACAGTATGGA TGGTTTGGAG 60
GCAGCAGAAA CAGAAAACAC TGTGGAAACA GGTAATGAGA ATGTGGCAGC GGTGCTCTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET

SMART

SM00542--FYRC
SM00541--FYRN
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00317--SET

Gene Ontology

GO:0044666--C:MLL3/4 complex
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0003723--F:RNA binding
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002314	Ailuropoda melanoleuca	72.57	0.00e+00	5831.00
IUUC-Aca-004705	Anolis carolinensis	71.76	0.00e+00	5838.00
IUUC-Ame-010612	Astyanax mexicanus	72.88	0.00e+00	864.00
IUUC-Bta-012322	Bos taurus	70.51	0.00e+00	5484.00
IUUC-Bol-015791	Brassica oleracea	34.03	4.00e-29	122.00
IUUC-Bra-017422	Brassica rapa	34.03	2.00e-29	123.00
IUUC-Cel-018354	Caenorhabditis elegans	35.67	2.00e-65	245.00
IUUC-Cja-019983	Callithrix jacchus	73.17	0.00e+00	6019.00
IUUC-Cfa-020903	Canis familiaris	71.59	0.00e+00	5853.00
IUUC-Cpo-021732	Cavia porcellus	70.43	0.00e+00	5660.00
IUUC-Csa-023083	Chlorocebus sabaeus	68.87	0.00e+00	4264.00
IUUC-Cho-024469	Choloepus hoffmanni	66.29	0.00e+00	1788.00
IUUC-Dre-028110	Danio rerio	64.65	0.00e+00	1238.00
IUUC-Dno-029932	Dasypus novemcinctus	75.82	0.00e+00	892.00
IUUC-Dor-030569	Dipodomys ordii	68.91	0.00e+00	3670.00
IUUC-Dme-031590	Drosophila melanogaster	33.67	8.00e-71	262.00
IUUC-Ete-032572	Echinops telfairi	76.08	0.00e+00	766.00
IUUC-Eca-033945	Equus caballus	70.10	0.00e+00	3986.00
IUUC-Eeu-034848	Erinaceus europaeus	40.19	4.00e-145	511.00
IUUC-Fca-035922	Felis catus	71.17	0.00e+00	5667.00
IUUC-Fal-037179	Ficedula albicollis	75.73	0.00e+00	866.00
IUUC-Gmo-039403	Gadus morhua	55.27	0.00e+00	1253.00
IUUC-Gga-040815	Gallus gallus	44.46	4.00e-115	411.00
IUUC-Gac-041896	Gasterosteus aculeatus	50.09	0.00e+00	1422.00
IUUC-Ggo-044812	Gorilla gorilla	71.10	0.00e+00	5821.00
IUUC-Hsa-046595	Homo sapiens	72.76	0.00e+00	6007.00
IUUC-Itr-048303	Ictidomys tridecemlineatus	71.43	0.00e+00	5749.00
IUUC-Lch-050086	Latimeria chalumnae	70.34	0.00e+00	2223.00
IUUC-Loc-052891	Lepisosteus oculatus	53.82	0.00e+00	2285.00
IUUC-Laf-054348	Loxodonta africana	71.17	0.00e+00	2561.00
IUUC-Mcc-054868	Macaca mulatta	72.78	0.00e+00	5949.00
IUUC-Meu-056322	Macropus eugenii	66.33	0.00e+00	1180.00
IUUC-Mga-059541	Meleagris gallopavo	91.93	0.00e+00	7554.00
IUUC-Mmr-061092	Microcebus murinus	69.02	0.00e+00	4256.00
IUUC-Mdo-062610	Monodelphis domestica	71.18	0.00e+00	1962.00
IUUC-Mmu-063666	Mus musculus	70.58	0.00e+00	5654.00
IUUC-Mac-064935	Musa acuminata	33.16	9.00e-30	125.00
IUUC-Mpu-066366	Mustela putorius furo	70.99	0.00e+00	5445.00
IUUC-Mlu-068201	Myotis lucifugus	67.27	0.00e+00	3346.00
IUUC-Nle-069232	Nomascus leucogenys	68.58	0.00e+00	4234.00
IUUC-Opr-070625	Ochotona princeps	67.74	0.00e+00	954.00
IUUC-Ont-072401	Oreochromis niloticus	49.78	0.00e+00	1139.00
IUUC-Oan-072945	Ornithorhynchus anatinus	72.36	0.00e+00	4288.00
IUUC-Ocu-074920	Oryctolagus cuniculus	68.12	0.00e+00	4173.00
IUUC-Ola-086436	Oryzias latipes	47.28	0.00e+00	1434.00
IUUC-Oga-088637	Otolemur garnettii	68.17	0.00e+00	3394.00
IUUC-Oar-089363	Ovis aries	69.04	0.00e+00	5391.00
IUUC-Ptr-091527	Pan troglodytes	72.61	0.00e+00	6039.00
IUUC-Pan-092102	Papio anubis	69.99	0.00e+00	5675.00
IUUC-Pma-094252	Petromyzon marinus	39.94	0.00e+00	669.00
IUUC-Ppa-095221	Physcomitrella patens	33.19	2.00e-29	123.00
IUUC-Pfo-096288	Poecilia formosa	47.00	0.00e+00	1557.00
IUUC-Pab-098241	Pongo abelii	72.59	0.00e+00	3843.00
IUUC-Pop-099585	Populus trichocarpa	31.94	3.00e-27	117.00
IUUC-Pca-100103	Procavia capensis	89.66	0.00e+00	1334.00
IUUC-Ppe-101920	Prunus persica	32.14	2.00e-26	114.00
IUUC-Pva-102238	Pteropus vampyrus	65.98	0.00e+00	2117.00
IUUC-Rno-105660	Rattus norvegicus	71.88	0.00e+00	817.00
IUUC-Sha-106550	Sarcophilus harrisii	70.39	0.00e+00	4351.00
IUUC-Sar-113183	Sorex araneus	58.81	5.00e-178	620.00
IUUC-Sbi-113816	Sorghum bicolor	36.63	2.00e-12	68.20
IUUC-Ssc-115678	Sus scrofa	75.46	0.00e+00	884.00
IUUC-Tgu-116677	Taeniopygia guttata	89.94	0.00e+00	7128.00
IUUC-Tru-118037	Takifugu rubripes	49.18	0.00e+00	1518.00
IUUC-Tsy-118932	Tarsius syrichta	72.83	0.00e+00	4305.00
IUUC-Tni-119970	Tetraodon nigroviridis	54.50	0.00e+00	1327.00
IUUC-Tca-121624	Theobroma cacao	32.46	6.00e-27	115.00
IUUC-Tbe-127625	Tupaia belangeri	67.47	5.00e-100	361.00
IUUC-Ttr-129051	Tursiops truncatus	69.97	0.00e+00	5335.00
IUUC-Vda-129876	Verticillium dahliae	52.08	7.00e-09	55.50
IUUC-Vpa-130236	Vicugna pacos	66.25	0.00e+00	1444.00
IUUC-Xtr-132455	Xenopus tropicalis	51.78	0.00e+00	931.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence