iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Opu-084139

Ensembl Protein ID

OPUNC02G05350.1

UniProt Accession

A0A0E0JWE4; A0A0E0JWE4_ORYPU

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
OPUNC02G05350	OPUNC02G05350.1	OPUNC02G05350.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	6.60e-61	207.4	2	317

Active Site

Position(s)	Description	Evidence
81	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
154	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 7    ewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCa 100
           +w  +e dPg+ft+l+++  +k+  qv+elysLd + l+ + +pv+gl+ l+k+++ ++ +r +           +d i ++ffakq i+N+Ca
   Q: 2    SWAAIENDPGVFTELLQQMQLKGL-QVDELYSLDLDALNDL-QPVYGLIVLYKWQPPEKDERPI-----------KDPIPNLFFAKQIINNACA 82
           7***********************.****************.9*************99999944...........489**************** PP
   S: 101  tyAllsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyeld 194
           t+A++svlln +     l ++l++lke+ k   p+ k+la+ n + ++ + ns+ar+e  +e+     ++++++++++hf+syv+++g lye d
   Q: 83   TQAIVSVLLNSQGI--TLSEELKKLKEFAKDLPPDLKGLAIVNCDSIRLASNSFARPEVPEEQ-----KSSVKEDDVYHFISYVPVDGVLYEFD 169
           **********9887..7****************************************976665.....556889******************** PP
   S: 195  glkpfPldlgkk...keteelkdklkvvraflerikllesdeirfnllaivadrrviktlrlnvlkid.................keLlkLlkd 268
           glk+ P+ lgk+     +  +   ++ v+   eri+  +++eirf+++ai ++rr + tl l+ l+                     + + l +
   Q: 170  GLKEGPISLGKCpggVGDIGWLTMVQPVI--QERIDRFSQNEIRFSVMAILKNRREMFTLELKELQRKrenllaqmgdpsanrhaPSVEQSLAE 261
           ***********976556888999999999..************************9999999877766799***********999445566777 PP
   S: 269  ieseeekieaqlddekekrkkfkiddirRtenydeficifikdlaregilrklvee 324
           + + +e   +++  e+ek kk+k ++irR++ny+ f++ f+k l + ++l+ l e+
   Q: 262  VAAHIEAVTEKIIMEEEKWKKWKTENIRRKHNYVPFLFNFLKILEERQQLKPLIEK 317
           888888888888889************************************99998 PP

Organism

Oryza punctata

Protein Sequence
(Fasta)

MSWAAIENDP GVFTELLQQM QLKGLQVDEL YSLDLDALND LQPVYGLIVL YKWQPPEKDE 60
RPIKDPIPNL FFAKQIINNA CATQAIVSVL LNSQGITLSE ELKKLKEFAK DLPPDLKGLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGAAATTGT ATCTGCAGAC CTGCAGGAGG GTGCACAGGG TTTTTTCGAC ATGTCTTGGG 60
CTGCAATCGA GAATGATCCT GGTAAAATTC AATTACCTCT ATGAAATAGA ACTACAAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005622--C:intracellular
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000878	Aegilops tauschii	81.79	1.00e-145	508.00
IUUC-Bdi-014551	Brachypodium distachyon	85.76	1.00e-155	541.00
IUUC-Oba-075354	Oryza barthii	97.57	5.00e-177	613.00
IUUC-Obr-076886	Oryza brachyantha	92.12	2.00e-159	553.00
IUUC-Ogu-078511	Oryza glumaepatula	96.65	2.00e-175	607.00
IUUC-Olo-080482	Oryza longistaminata	96.96	3.00e-176	610.00
IUUC-Oni-082729	Oryza nivara	96.66	5.00e-175	606.00
IUUC-Oru-084441	Oryza rufipogon	97.26	3.00e-177	613.00
IUUC-Osa-085606	Oryza sativa	97.26	2.00e-177	613.00
IUUC-Sit-110523	Setaria italica	88.01	9.00e-155	538.00
IUUC-Sbi-114404	Sorghum bicolor	86.32	2.00e-147	514.00
IUUC-Tae-123169	Triticum aestivum	85.20	1.00e-149	521.00
IUUC-Tur-126366	Triticum urartu	84.42	2.00e-143	501.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence