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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-046314
UUCD1 version UUC-HoS-00699
Ensembl Protein ID ENSP00000257575.4
UniProt Accession Q96EX2; E9PAM7; Q96SU5; RNFT2_HUMAN
Genbank Protein ID BAB55182.1; EAW98091.1; AAH11878.1
Protein Name RING finger and transmembrane domain-containing protein 2; Transmembrane protein 118
Genbank Nucleotide ID AK027533; AK093164; BC011878
Gene Name RNFT2; TMEM118
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000135119.14 ENST00000257575.8 ENSP00000257575.4
ENSG00000135119.14 ENST00000407967.7 ENSP00000385669.3
ENSG00000135119.14 ENST00000319176.11 ENSP00000321405.8
ENSG00000135119.14 ENST00000547718.5 ENSP00000447294.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
TargetScanRepTarmiRNAMapSomamiR
miRcodeRAID2
Protein-protein Interaction
IIDMentha
Disease-associated Variation
GWASdb
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
BioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 1.20e-06 30.6 384 422
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiC+ +f++ pl+l C+Hvf+++Cl  w        +e +CPlCr
   Q: 384  CAICQAEFRE-PLILLCQHVFCEECLCLW------LDRERTCPLCR 422
           ********99.999***************......**********8 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MWLFTVNQVL RKMQRRHSSN TDNIPPERNR SQALSSEASV DEGGVFESLK AEAASPPALF 60
SGLSGSLPTS SFPSSLVLGS SAGGGDVFIQ MPASREEGGG RGEGGAYHHR QPHHHFHHGG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046314|E3,RING|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AAAGGGGGCG GACAATCGCG TGAGTGCTGC GGGCGTAGCT GTGCCCGGGT CCTAGCGCCG 60
GACCCGGCGA CGCCAAGAAA CCACCCAATA GGAGGCCGGA AGCATCGGAA GTCACATGCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046314|E3,RING|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001370--BIR_rpt
IPR001841--Znf_RING
IPR017907--Znf_RING_CS
PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2
SMART

SM00184--RING
Gene Ontology

GO:0016021--C:integral component of membrane
GO:0008270--F:zinc ion binding
KEGG hsa:84900
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000709 Aegilops tauschii 26.77 2.00e-28 119.00
IUUC-Aml-002361 Ailuropoda melanoleuca 95.24 0.00e+00 771.00
IUUC-Apl-003413 Anas platyrhynchos 83.67 0.00e+00 684.00
IUUC-Aca-005181 Anolis carolinensis 81.22 0.00e+00 692.00
IUUC-Aly-005949 Arabidopsis lyrata 30.95 1.00e-39 157.00
IUUC-Ath-007582 Arabidopsis thaliana 30.61 5.00e-41 162.00
IUUC-Ame-011821 Astyanax mexicanus 65.32 6.00e-164 570.00
IUUC-Bta-012475 Bos taurus 91.76 0.00e+00 779.00
IUUC-Bdi-014696 Brachypodium distachyon 31.47 2.00e-39 156.00
IUUC-Bol-015956 Brassica oleracea 30.33 2.00e-37 150.00
IUUC-Bra-016928 Brassica rapa 30.95 2.00e-39 156.00
IUUC-Cel-018190 Caenorhabditis elegans 25.42 7.00e-24 105.00
IUUC-Cja-019920 Callithrix jacchus 98.87 0.00e+00 776.00
IUUC-Cfa-020715 Canis familiaris 94.64 0.00e+00 772.00
IUUC-Cpo-021829 Cavia porcellus 92.81 0.00e+00 724.00
IUUC-Cre-022592 Chlamydomonas reinhardtii 43.24 4.00e-11 62.40
IUUC-Csa-023156 Chlorocebus sabaeus 98.65 0.00e+00 719.00
IUUC-Cho-025100 Choloepus hoffmanni 94.05 0.00e+00 722.00
IUUC-Dre-027857 Danio rerio 65.25 5.00e-166 577.00
IUUC-Dno-030046 Dasypus novemcinctus 89.73 0.00e+00 754.00
IUUC-Dor-030446 Dipodomys ordii 72.13 3.00e-165 574.00
IUUC-Dme-031681 Drosophila melanogaster 30.65 4.00e-31 129.00
IUUC-Eca-033852 Equus caballus 87.58 0.00e+00 733.00
IUUC-Fca-036281 Felis catus 94.63 0.00e+00 767.00
IUUC-Fal-037647 Ficedula albicollis 87.50 3.00e-157 547.00
IUUC-Gga-040867 Gallus gallus 83.45 0.00e+00 687.00
IUUC-Gma-044109 Glycine max 31.63 9.00e-37 148.00
IUUC-Hvu-047080 Hordeum vulgare 29.08 2.00e-32 132.00
IUUC-Lch-049901 Latimeria chalumnae 69.42 2.00e-165 575.00
IUUC-Lpe-051163 Leersia perrieri 30.61 6.00e-40 158.00
IUUC-Loc-051924 Lepisosteus oculatus 66.74 2.00e-168 585.00
IUUC-Laf-053448 Loxodonta africana 92.68 0.00e+00 770.00
IUUC-Mcc-054949 Macaca mulatta 99.32 0.00e+00 729.00
IUUC-Meu-056283 Macropus eugenii 67.50 4.00e-139 488.00
IUUC-Mtr-057979 Medicago truncatula 29.23 1.00e-38 154.00
IUUC-Mga-059843 Meleagris gallopavo 83.22 0.00e+00 681.00
IUUC-Mmr-061235 Microcebus murinus 87.64 0.00e+00 699.00
IUUC-Mdo-062268 Monodelphis domestica 83.30 0.00e+00 693.00
IUUC-Mmu-063985 Mus musculus 91.70 0.00e+00 781.00
IUUC-Mac-065493 Musa acuminata 30.62 2.00e-42 166.00
IUUC-Mpu-066469 Mustela putorius furo 94.64 0.00e+00 771.00
IUUC-Mlu-067707 Myotis lucifugus 92.22 0.00e+00 753.00
IUUC-Ont-072228 Oreochromis niloticus 64.89 7.00e-162 563.00
IUUC-Ocu-073985 Oryctolagus cuniculus 87.19 0.00e+00 735.00
IUUC-Oba-075245 Oryza barthii 30.28 3.00e-33 135.00
IUUC-Obr-076737 Oryza brachyantha 30.68 1.00e-28 119.00
IUUC-Ogl-077684 Oryza glaberrima 30.61 1.00e-39 157.00
IUUC-Ogu-078859 Oryza glumaepatula 30.61 2.00e-39 156.00
IUUC-Oin-079424 Oryza indica 30.61 2.00e-39 156.00
IUUC-Ome-081614 Oryza meridionalis 30.95 1.00e-34 140.00
IUUC-Oni-082296 Oryza nivara 30.95 3.00e-35 142.00
IUUC-Opu-083546 Oryza punctata 30.95 5.00e-35 142.00
IUUC-Oru-084510 Oryza rufipogon 30.95 6.00e-35 142.00
IUUC-Osa-085729 Oryza sativa 30.61 2.00e-39 157.00
IUUC-Ola-086621 Oryzias latipes 61.74 2.00e-149 522.00
IUUC-Olu-087799 Ostreococcus lucimarinus 29.56 5.00e-15 73.90
IUUC-Ptr-091587 Pan troglodytes 99.77 0.00e+00 765.00
IUUC-Pan-092883 Papio anubis 99.32 0.00e+00 729.00
IUUC-Psi-093826 Pelodiscus sinensis 82.09 0.00e+00 677.00
IUUC-Ppa-095990 Physcomitrella patens 29.62 4.00e-36 145.00
IUUC-Pfo-096621 Poecilia formosa 57.26 3.00e-149 521.00
IUUC-Pop-099270 Populus trichocarpa 32.54 1.00e-34 140.00
IUUC-Pca-100148 Procavia capensis 93.99 0.00e+00 707.00
IUUC-Ppe-101974 Prunus persica 31.97 1.00e-37 150.00
IUUC-Pva-102165 Pteropus vampyrus 92.63 0.00e+00 746.00
IUUC-Rno-105220 Rattus norvegicus 91.46 0.00e+00 783.00
IUUC-Smo-109495 Selaginella moellendorffii 30.14 5.00e-38 151.00
IUUC-Sit-110120 Setaria italica 30.27 9.00e-39 154.00
IUUC-Sly-111923 Solanum lycopersicum 29.93 2.00e-39 156.00
IUUC-Stu-112700 Solanum tuberosum 29.06 2.00e-32 134.00
IUUC-Sbi-114889 Sorghum bicolor 30.27 1.00e-34 141.00
IUUC-Ssc-115358 Sus scrofa 94.64 0.00e+00 796.00
IUUC-Tru-117949 Takifugu rubripes 62.91 1.00e-158 552.00
IUUC-Tni-120152 Tetraodon nigroviridis 69.45 2.00e-132 465.00
IUUC-Tca-121155 Theobroma cacao 30.95 1.00e-37 150.00
IUUC-Tae-124618 Triticum aestivum 29.59 8.00e-40 158.00
IUUC-Tur-126400 Triticum urartu 29.71 8.00e-36 145.00
IUUC-Ttr-128557 Tursiops truncatus 94.87 0.00e+00 783.00
IUUC-Vvi-131323 Vitis vinifera 30.27 6.00e-34 138.00
IUUC-Xtr-132785 Xenopus tropicalis 66.44 5.00e-143 501.00
IUUC-Xma-133737 Xiphophorus maculatus 61.95 1.00e-155 543.00
Created Date 25-Jun-2017

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