iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067682

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02017271

Gene Name

UBE2K

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000011216.2	ENSMLUT00000011206.2	ENSMLUP00000010212.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.40e-44	151.3	19	144
UBD/Alpha-Helix/UBA	4.50e-11	42.6	159	197

Active Site

Position(s)	Description	Evidence
90	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 11   kdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkeeekWspalsv 98
           k+++++i++++vde ++te++ +i Gp+dtpYegg ++lei++pe+YPf+PPkv+f+tki+hPn+++  G++Cl+ilk  ++W +a+++
   Q: 19   KTSKNQIKVDLVDE-NFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVtGAICLDILK--DQWAAAMTL 104
           567789********.9***************************************************99********9..********* PP
   S: 99   esvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++vlls+q+lla ++p++p+++ +a+++k+n+e++k+++r
   Q: 105  RTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTAR 144
           *************************************986 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyLld 40
           e++ k+e+l++MGFdr++++ aL + ++++e A+e+Ll+
   Q: 159  EYTKKIENLCAMGFDRNAVIVALSSKSWDVETATELLLS 197
           6789*********************************97 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

NILISSIKND SKRTSTNFKT SKNQIKVDLV DENFTELRGE IAGPPDTPYE GGRYQLEIKI 60
PETYPFNPPK VRFITKIWHP NISSVTGAIC LDILKDQWAA AMTLRTVLLS LQALLAAAEP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATATTTTAA TCTCAAGTAT AAAAAATGAT AGTAAACGAA CCAGTACTAA TTAGGATGTT 60
TAATTTTGAA ATGCATAATG TTTTTTATCT TACGCTCTTA TTAAAAGATA AAATTAATTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50030--UBA
PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00627--UBA
PF00179--UQ_con

SMART

SM00165--UBA

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0032433--C:filopodium tip
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0035458--P:cellular response to interferon-beta
GO:0010994--P:free ubiquitin chain polymerization
GO:0010800--P:positive regulation of peptidyl-threonine phosphorylation
GO:0060340--P:positive regulation of type I interferon-mediated signaling pathway
GO:0070936--P:protein K48-linked ubiquitination
GO:0032434--P:regulation of proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000621	Aegilops tauschii	55.17	2.00e-25	109.00
IUUC-Aml-001286	Ailuropoda melanoleuca	92.93	3.00e-100	357.00
IUUC-Atr-003063	Amborella trichopoda	51.46	7.00e-38	149.00
IUUC-Apl-004122	Anas platyrhynchos	99.43	2.00e-95	340.00
IUUC-Aca-004565	Anolis carolinensis	99.45	4.00e-100	356.00
IUUC-Aly-006390	Arabidopsis lyrata	51.72	4.00e-42	164.00
IUUC-Ath-006637	Arabidopsis thaliana	50.00	3.00e-39	154.00
IUUC-Ago-007714	Ashbya gossypii	47.47	9.00e-36	142.00
IUUC-Acl-008189	Aspergillus clavatus	55.65	4.00e-26	111.00
IUUC-Afl-008489	Aspergillus flavus	44.57	3.00e-27	115.00
IUUC-Afu-008850	Aspergillus fumigatus	42.05	7.00e-27	114.00
IUUC-Ani-009361	Aspergillus nidulans	57.26	2.00e-24	105.00
IUUC-Ang-009548	Aspergillus niger	54.55	5.00e-25	107.00
IUUC-Aor-010105	Aspergillus oryzae	44.57	3.00e-27	115.00
IUUC-Ate-010389	Aspergillus terreus	43.48	5.00e-27	114.00
IUUC-Ame-011454	Astyanax mexicanus	89.90	1.00e-97	348.00
IUUC-Bgr-012255	Blumeria graminis	54.76	1.00e-31	129.00
IUUC-Bta-012992	Bos taurus	92.93	3.00e-100	357.00
IUUC-Bci-013806	Botrytis cinerea	44.15	3.00e-35	141.00
IUUC-Bdi-015024	Brachypodium distachyon	49.73	1.00e-38	152.00
IUUC-Bol-015985	Brassica oleracea	51.72	2.00e-42	165.00
IUUC-Bra-016805	Brassica rapa	51.72	1.00e-42	165.00
IUUC-Cel-018353	Caenorhabditis elegans	49.75	1.00e-52	198.00
IUUC-Cja-019051	Callithrix jacchus	92.42	3.00e-99	353.00
IUUC-Cfa-020016	Canis familiaris	92.93	3.00e-100	357.00
IUUC-Cpo-022026	Cavia porcellus	92.93	3.00e-100	357.00
IUUC-Cre-022987	Chlamydomonas reinhardtii	50.84	6.00e-40	156.00
IUUC-Csa-023059	Chlorocebus sabaeus	92.93	3.00e-100	357.00
IUUC-Cho-024276	Choloepus hoffmanni	96.60	1.00e-73	267.00
IUUC-Cin-025598	Ciona intestinalis	61.93	1.00e-50	192.00
IUUC-Csv-025831	Ciona savignyi	63.07	7.00e-50	189.00
IUUC-Cgl-026449	Colletotrichum gloeosporioides	51.52	7.00e-33	133.00
IUUC-Cne-027068	Cryptococcus neoformans	43.72	1.00e-38	152.00
IUUC-Dre-028139	Danio rerio	89.90	1.00e-97	348.00
IUUC-Dno-029169	Dasypus novemcinctus	92.42	3.00e-98	350.00
IUUC-Dor-030382	Dipodomys ordii	78.79	9.00e-79	285.00
IUUC-Dse-031335	Dothistroma septosporum	52.03	7.00e-36	143.00
IUUC-Dme-032003	Drosophila melanogaster	62.94	2.00e-63	234.00
IUUC-Ete-032868	Echinops telfairi	83.84	1.00e-78	285.00
IUUC-Eca-033428	Equus caballus	92.93	3.00e-100	357.00
IUUC-Eeu-035103	Erinaceus europaeus	73.44	3.00e-49	186.00
IUUC-Fca-035366	Felis catus	92.93	3.00e-100	357.00
IUUC-Fal-037016	Ficedula albicollis	92.93	3.00e-100	357.00
IUUC-Fox-037969	Fusarium oxysporum	46.84	1.00e-32	132.00
IUUC-Fso-038296	Fusarium solani	46.11	6.00e-34	137.00
IUUC-Gmo-039135	Gadus morhua	88.89	2.00e-96	344.00
IUUC-Ggr-039768	Gaeumannomyces graminis	52.17	8.00e-24	103.00
IUUC-Gga-041018	Gallus gallus	92.42	5.00e-100	356.00
IUUC-Gac-041503	Gasterosteus aculeatus	89.39	3.00e-97	347.00
IUUC-Gma-042779	Glycine max	52.91	4.00e-41	160.00
IUUC-Ggo-045032	Gorilla gorilla	92.93	3.00e-100	357.00
IUUC-Hsa-046490	Homo sapiens	92.93	3.00e-100	357.00
IUUC-Itr-048373	Ictidomys tridecemlineatus	92.93	3.00e-100	357.00
IUUC-Kpa-049297	Komagataella pastoris	48.68	2.00e-32	132.00
IUUC-Lch-050588	Latimeria chalumnae	68.72	3.00e-76	277.00
IUUC-Lpe-051070	Leersia perrieri	46.67	1.00e-29	122.00
IUUC-Loc-052549	Lepisosteus oculatus	90.40	5.00e-98	349.00
IUUC-Lma-052949	Leptosphaeria maculans	57.72	6.00e-36	144.00
IUUC-Laf-053688	Loxodonta africana	91.54	2.00e-98	351.00
IUUC-Mcc-055606	Macaca mulatta	92.93	3.00e-100	357.00
IUUC-Mor-056946	Magnaporthe oryzae	41.48	4.00e-22	97.80
IUUC-Mpo-057441	Magnaporthe poae	54.48	8.00e-24	103.00
IUUC-Mtr-058002	Medicago truncatula	52.33	3.00e-41	161.00
IUUC-Mla-059007	Melampsora laricipopulina	43.16	5.00e-37	147.00
IUUC-Mga-059254	Meleagris gallopavo	99.44	5.00e-98	349.00
IUUC-Mvi-060346	Microbotryum violaceum	42.54	4.00e-31	127.00
IUUC-Mmr-061211	Microcebus murinus	92.93	3.00e-100	357.00
IUUC-Mdo-062458	Monodelphis domestica	91.92	1.00e-97	348.00
IUUC-Mmu-063648	Mus musculus	92.93	3.00e-100	357.00
IUUC-Mac-065447	Musa acuminata	50.54	2.00e-39	154.00
IUUC-Mpu-066407	Mustela putorius furo	92.93	1.00e-99	355.00
IUUC-Nfi-068517	Neosartorya fischeri	42.05	7.00e-27	114.00
IUUC-Ncr-068749	Neurospora crassa	53.97	6.00e-36	143.00
IUUC-Nle-069712	Nomascus leucogenys	99.45	7.00e-99	352.00
IUUC-Opr-070651	Ochotona princeps	92.93	3.00e-100	357.00
IUUC-Ont-071595	Oreochromis niloticus	89.39	3.00e-97	347.00
IUUC-Oan-073058	Ornithorhynchus anatinus	100.00	7.00e-79	285.00
IUUC-Ocu-074939	Oryctolagus cuniculus	92.93	3.00e-100	357.00
IUUC-Oba-075530	Oryza barthii	50.00	1.00e-29	122.00
IUUC-Obr-076838	Oryza brachyantha	53.99	4.00e-29	120.00
IUUC-Ogl-077606	Oryza glaberrima	50.00	1.00e-29	122.00
IUUC-Ogu-078238	Oryza glumaepatula	50.00	1.00e-29	122.00
IUUC-Oin-079643	Oryza indica	53.94	3.00e-29	121.00
IUUC-Ome-081274	Oryza meridionalis	50.00	1.00e-29	122.00
IUUC-Oni-082651	Oryza nivara	50.00	1.00e-29	122.00
IUUC-Opu-083933	Oryza punctata	50.00	2.00e-29	121.00
IUUC-Oru-085054	Oryza rufipogon	50.00	2.00e-29	121.00
IUUC-Osa-085716	Oryza sativa	53.94	3.00e-29	121.00
IUUC-Ola-087043	Oryzias latipes	89.39	3.00e-97	347.00
IUUC-Olu-087846	Ostreococcus lucimarinus	48.86	5.00e-41	160.00
IUUC-Oga-088897	Otolemur garnettii	99.44	6.00e-98	349.00
IUUC-Oar-089673	Ovis aries	92.42	2.00e-99	354.00
IUUC-Ptr-091295	Pan troglodytes	92.93	3.00e-100	357.00
IUUC-Pan-092034	Papio anubis	92.82	1.00e-98	352.00
IUUC-Psi-093498	Pelodiscus sinensis	92.93	3.00e-100	357.00
IUUC-Pma-094115	Petromyzon marinus	81.73	4.00e-87	313.00
IUUC-Pno-095102	Phaeosphaeria nodorum	43.72	4.00e-37	147.00
IUUC-Ppa-095326	Physcomitrella patens	46.15	2.00e-37	148.00
IUUC-Pfo-096940	Poecilia formosa	89.39	4.00e-97	346.00
IUUC-Pab-098279	Pongo abelii	92.93	3.00e-100	357.00
IUUC-Pop-099543	Populus trichocarpa	47.72	2.00e-42	164.00
IUUC-Pca-100782	Procavia capensis	92.42	3.00e-98	350.00
IUUC-Ppe-101789	Prunus persica	52.00	3.00e-36	144.00
IUUC-Pva-102147	Pteropus vampyrus	100.00	2.00e-52	198.00
IUUC-Pgr-103643	Puccinia graminis	47.14	4.00e-36	144.00
IUUC-Ptt-103772	Puccinia triticina	48.48	9.00e-35	140.00
IUUC-Pte-104370	Pyrenophora teres	56.91	2.00e-35	142.00
IUUC-Pyt-104592	Pyrenophora triticirepentis	44.26	2.00e-35	142.00
IUUC-Rno-104984	Rattus norvegicus	92.93	3.00e-100	357.00
IUUC-Sce-106394	Saccharomyces cerevisiae	45.09	2.00e-33	135.00
IUUC-Sha-106848	Sarcophilus harrisii	100.00	2.00e-99	353.00
IUUC-Ssl-108609	Sclerotinia sclerotiorum	46.28	2.00e-38	152.00
IUUC-Smo-109656	Selaginella moellendorffii	50.87	2.00e-38	151.00
IUUC-Sit-110639	Setaria italica	52.41	2.00e-37	147.00
IUUC-Sly-110978	Solanum lycopersicum	52.30	2.00e-42	165.00
IUUC-Stu-112088	Solanum tuberosum	52.30	7.00e-43	166.00
IUUC-Sar-113285	Sorex araneus	84.36	3.00e-76	276.00
IUUC-Sbi-113986	Sorghum bicolor	52.41	3.00e-37	147.00
IUUC-Sre-115046	Sporisorium reilianum	50.38	4.00e-35	141.00
IUUC-Ssc-116314	Sus scrofa	92.93	3.00e-100	357.00
IUUC-Tgu-117427	Taeniopygia guttata	100.00	3.00e-98	350.00
IUUC-Tru-118618	Takifugu rubripes	84.85	3.00e-92	330.00
IUUC-Tsy-119208	Tarsius syrichta	92.93	2.00e-100	357.00
IUUC-Tni-119667	Tetraodon nigroviridis	89.90	1.00e-97	348.00
IUUC-Tca-121446	Theobroma cacao	52.87	8.00e-43	166.00
IUUC-Tre-122053	Trichoderma reesei	39.88	6.00e-30	124.00
IUUC-Tvi-122533	Trichoderma virens	38.95	2.00e-29	122.00
IUUC-Tae-124726	Triticum aestivum	50.27	5.00e-31	127.00
IUUC-Tme-127024	Tuber melanosporum	53.57	1.00e-37	149.00
IUUC-Tbe-127752	Tupaia belangeri	93.33	9.00e-99	352.00
IUUC-Ttr-128287	Tursiops truncatus	100.00	9.00e-98	348.00
IUUC-Uma-129512	Ustilago maydis	41.08	1.00e-34	139.00
IUUC-Vda-129947	Verticillium dahliae	41.71	7.00e-31	127.00
IUUC-Vpa-130481	Vicugna pacos	92.89	2.00e-99	354.00
IUUC-Vvi-131429	Vitis vinifera	45.13	2.00e-39	155.00
IUUC-Xtr-132710	Xenopus tropicalis	76.50	2.00e-85	307.00
IUUC-Xma-134308	Xiphophorus maculatus	88.89	1.00e-96	345.00
IUUC-Yli-134523	Yarrowia lipolytica	48.30	1.00e-32	132.00
IUUC-Zma-135733	Zea mays	51.12	1.00e-35	142.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence