iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-006949

UUCD1 version

UUC-ArT-01047

Ensembl Protein ID

AT4G25160.1

UniProt Accession

Q9SW11; PUB35_ARATH

Genbank Protein ID

CAB36758.1; CAB79425.1; AEE85018.1; AT4G25160.1

Protein Name

U-box domain-containing protein 35; Plant U-box protein 35; E3 ubiquitin ligase; RING-type E3 ubiquitin transferase; Serine/threonine-protein kinase

Genbank Nucleotide ID

AL035396; AL161562; CP002687; BX828107

Gene Name

PUB35; At4g25160; F13M23.300; F24A6.13

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT4G25160	AT4G25160.1	AT4G25160.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	HINT	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.90e-21	76.2	766	834

Active Site

Position(s)	Description	Evidence
602	Proton acceptor	ECO:0000255\|PROSITE-ProRule:PRU00159, ECO:0000255\|PROSITE-ProRule:PRU10027}

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawcee 71
           +p +f+Cp+ +++M++P+v+++G+tydr +Ie+wl++ ++ +P+t++pl++++l Pn+tl   i +w+++
   Q: 766  PPTHFICPLLKDVMNEPCVAADGYTYDRHAIEEWLKEHNT-SPMTDSPLHSKNLLPNYTLYTAIMEWRST 834
           799*******************************998887.**************************986 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Functions as an E3 ubiquitin ligase.

Protein Sequence
(Fasta)

MSRSPDKLAL PPPPPPPPSR TVVVALSGSS KSKYVVTWAI EKFATEGNVG FKLLHIHPMI 60
TSVPTPMGNA IPISEVRDDV VTAYRQEILW QSEEMLKPYT KLFVRRKVAV EVLVIESDNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCAAGGCCT AAGGTTGGAG AAAACTTCTT TCTTTTAGAA CACACTCTCC TTCTGTCACT 60
CTGATAATGA AGAAAATTCA GGCGAGAGAA CAAAAGAGTA TATACCCAGG ACTGATCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR014729--Rossmann-like_a/b/a_fold
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008271--Ser/Thr_kinase_AS
IPR003613--Ubox_domain
IPR006016--UspA
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS51698--U_BOX

Pfam

PF07714--Pkinase_Tyr
PF04564--U-box
PF00582--Usp

SMART

SM00220--S_TKc
SM00504--Ubox

Gene Ontology

GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006950--P:response to stress

KEGG

ath:AT4G25160

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000476	Aegilops tauschii	47.30	3.00e-128	451.00
IUUC-Atr-002478	Amborella trichopoda	58.93	3.00e-164	571.00
IUUC-Aly-005861	Arabidopsis lyrata	94.49	0.00e+00	1479.00
IUUC-Bdi-014574	Brachypodium distachyon	47.32	8.00e-131	460.00
IUUC-Bol-016329	Brassica oleracea	87.22	0.00e+00	1319.00
IUUC-Bra-017921	Brassica rapa	88.05	0.00e+00	1351.00
IUUC-Gma-043854	Glycine max	52.19	0.00e+00	766.00
IUUC-Olo-080520	Oryza longistaminata	53.88	1.00e-136	479.00
IUUC-Pop-100071	Populus trichocarpa	56.48	0.00e+00	874.00
IUUC-Ppe-101208	Prunus persica	57.60	0.00e+00	862.00
IUUC-Sit-110427	Setaria italica	54.14	5.00e-157	547.00
IUUC-Sly-111796	Solanum lycopersicum	55.61	0.00e+00	828.00
IUUC-Sbi-113963	Sorghum bicolor	55.12	3.00e-141	494.00
IUUC-Tca-121565	Theobroma cacao	57.47	0.00e+00	898.00
IUUC-Vvi-131503	Vitis vinifera	56.74	0.00e+00	797.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence