iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pma-094100

Ensembl Protein ID

ENSPMAP00000010612.1

UniProt Accession

S4RZH1; S4RZH1_PETMA

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000009644.1	ENSPMAT00000010658.1	ENSPMAP00000010612.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.90e-13	48.1	2	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v +lyd+e  n d++ +kkGd++++i   ++ ++W++++  +   +G +P+n+v+k++
   Q: 2    LVVALYDFEQLNPDDMGFKKGDKMRII---QERGEWWMAELMDGSHKGYIPSNYVAKAN 57
           689************************...8889*****999999***********987 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

ELVVALYDFE QLNPDDMGFK KGDKMRIIQE RGEWWMAELM DGSHKGYIPS NYVAKANSLE 60
TEEWFFSGVS RKEGERLLLA PGNSIGAYLL RDSESNKGSY SLSVRDYDIT NGDVVRHYKI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGCTCGTGG TGGCCTTATA TGACTTCGAG CAGCTGAACC CCGACGACAT GGGCTTCAAG 60
AAAGGAGATA AAATGCGAAT CATCCAGGAG TAAGTTGGCG CTTTGCTCTC CTAATGTCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000727	Aegilops tauschii	28.67	5.00e-21	95.10
IUUC-Aca-004333	Anolis carolinensis	70.11	0.00e+00	676.00
IUUC-Cre-022669	Chlamydomonas reinhardtii	28.51	3.00e-19	87.80
IUUC-Eca-034193	Equus caballus	69.06	0.00e+00	677.00
IUUC-Gma-043938	Glycine max	32.00	3.00e-23	102.00
IUUC-Lch-049991	Latimeria chalumnae	71.01	0.00e+00	661.00
IUUC-Mtr-057737	Medicago truncatula	31.96	1.00e-21	97.10
IUUC-Mac-064539	Musa acuminata	28.81	2.00e-19	89.70
IUUC-Opu-083538	Oryza punctata	33.33	1.00e-24	106.00
IUUC-Ptr-091409	Pan troglodytes	68.61	0.00e+00	673.00
IUUC-Pab-098601	Pongo abelii	68.61	0.00e+00	673.00
IUUC-Pop-099554	Populus trichocarpa	30.15	3.00e-23	102.00
IUUC-Sha-106643	Sarcophilus harrisii	69.44	0.00e+00	671.00
IUUC-Smo-109113	Selaginella moellendorffii	29.10	2.00e-24	104.00
IUUC-Sit-109809	Setaria italica	33.02	9.00e-24	103.00
IUUC-Sly-111528	Solanum lycopersicum	29.96	4.00e-25	108.00
IUUC-Stu-112331	Solanum tuberosum	30.28	3.00e-26	112.00
IUUC-Tru-118284	Takifugu rubripes	65.92	0.00e+00	658.00
IUUC-Tsy-119440	Tarsius syrichta	68.61	0.00e+00	666.00
IUUC-Tni-120005	Tetraodon nigroviridis	65.92	0.00e+00	659.00
IUUC-Tca-121341	Theobroma cacao	35.92	1.00e-22	100.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence