iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090999

UUCD1 version

UUC-PaT-00023

Ensembl Protein ID

ENSPTRP00000011838.2

UniProt Accession

H2Q973; H2Q973_PANTR

Genbank Protein ID

JAA06175.1; JAA13898.1; JAA23885.1; JAA39062.1

Protein Name

Vacuolar protein sorting 18 homolog

Genbank Nucleotide ID

AACZ03100088; GABF01008247; GABD01009215; GABE01005677

Gene Name

VPS18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000006936.4	ENSPTRT00000012787.2	ENSPTRP00000011838.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.10e-06	26.5	853	947

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlp......CgHvfhadCl.qkw.pglknssskefr........................................ 41
           Ca+C  df   pl+++      CgH+fhadCl q++ pgl+  ++k++r                                        
   Q: 853  CATC--DF---PLLNRpfylflCGHMFHADCLlQAVrPGLP--AYKQARleelqrklgaapppakgsarakeaeggaatagpsreqlka 934
           9***..99...66555666668*********9788887777..8888877777777777777777777788888888888888888888 PP
   S: 42   .........CPlC 45
                    C++C
   Q: 935  dldelvaaeCVYC 947
           8888888888887 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MASILDEYEN SLSRSAVLQP GCPSVGIPHS GYVNAQLEKE VPIFTKQRID FTPSERITSL 60
VVSSNQLCMT LGKDTLLRID LGKANEPNHV ELGRKDDAKV HKMFLDHTGS HLLIALSSTE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCGCGTCA CGGGGGCGGG AGTCAGCTGA GCTGCCGGGG CGAGGTTGGG ATCACCTGGC 60
ACCGGCTGAA GGGAGCCTGT GATTTTTTTG TAGCGGGGGC GGGGAGTAGG GTGCAAGACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000547--Clathrin_H-chain/VPS_repeat
IPR007810--Pep3_Vps18
IPR011990--TPR-like_helical_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50236--CHCR

Pfam

PF00637--Clathrin
PF05131--Pep3_Vps18

Gene Ontology

GO:0005884--C:actin filament
GO:0030123--C:AP-3 adaptor complex
GO:0033263--C:CORVET complex
GO:0005769--C:early endosome
GO:0005768--C:endosome
GO:0030897--C:HOPS complex
GO:0005770--C:late endosome
GO:0005765--C:lysosomal membrane
GO:0030674--F:protein binding, bridging
GO:0007032--P:endosome organization
GO:0008333--P:endosome to lysosome transport
GO:0006886--P:intracellular protein transport
GO:0007040--P:lysosome organization
GO:0035542--P:regulation of SNARE complex assembly
GO:0006904--P:vesicle docking involved in exocytosis
GO:0046718--P:viral entry into host cell

KEGG

ptr:467792

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000419	Aegilops tauschii	32.24	5.00e-109	389.00
IUUC-Aml-001240	Ailuropoda melanoleuca	97.33	0.00e+00	1875.00
IUUC-Atr-003125	Amborella trichopoda	32.62	1.00e-121	430.00
IUUC-Apl-004181	Anas platyrhynchos	72.48	0.00e+00	1483.00
IUUC-Aca-004437	Anolis carolinensis	72.38	0.00e+00	1464.00
IUUC-Aly-006046	Arabidopsis lyrata	33.23	1.00e-134	473.00
IUUC-Ath-006932	Arabidopsis thaliana	33.47	5.00e-134	472.00
IUUC-Ago-007800	Ashbya gossypii	24.11	6.00e-57	216.00
IUUC-Acl-008035	Aspergillus clavatus	31.41	1.00e-111	397.00
IUUC-Afl-008714	Aspergillus flavus	31.17	4.00e-111	395.00
IUUC-Afu-009063	Aspergillus fumigatus	32.42	3.00e-113	402.00
IUUC-Ani-009384	Aspergillus nidulans	32.80	2.00e-115	410.00
IUUC-Ang-009507	Aspergillus niger	32.27	3.00e-111	396.00
IUUC-Aor-010094	Aspergillus oryzae	31.17	9.00e-111	394.00
IUUC-Ate-010421	Aspergillus terreus	31.53	7.00e-97	348.00
IUUC-Ame-011797	Astyanax mexicanus	65.54	0.00e+00	1305.00
IUUC-Bgr-012107	Blumeria graminis	31.46	2.00e-109	390.00
IUUC-Bta-012339	Bos taurus	96.81	0.00e+00	1883.00
IUUC-Bci-013895	Botrytis cinerea	33.92	2.00e-119	423.00
IUUC-Bdi-014554	Brachypodium distachyon	34.09	4.00e-127	449.00
IUUC-Bol-015270	Brassica oleracea	33.54	1.00e-135	477.00
IUUC-Bra-017424	Brassica rapa	33.09	2.00e-131	463.00
IUUC-Cel-018455	Caenorhabditis elegans	26.01	2.00e-86	314.00
IUUC-Cja-019629	Callithrix jacchus	98.05	0.00e+00	1920.00
IUUC-Cfa-020425	Canis familiaris	97.23	0.00e+00	1870.00
IUUC-Cpo-021349	Cavia porcellus	95.59	0.00e+00	1840.00
IUUC-Cre-022799	Chlamydomonas reinhardtii	29.52	2.00e-26	115.00
IUUC-Csa-023559	Chlorocebus sabaeus	99.28	0.00e+00	1933.00
IUUC-Cho-024862	Choloepus hoffmanni	88.86	0.00e+00	1387.00
IUUC-Cin-025599	Ciona intestinalis	41.18	7.00e-176	610.00
IUUC-Csv-026152	Ciona savignyi	42.84	0.00e+00	764.00
IUUC-Cgl-026551	Colletotrichum gloeosporioides	31.00	6.00e-112	398.00
IUUC-Cne-026907	Cryptococcus neoformans	31.12	2.00e-110	394.00
IUUC-Dre-027747	Danio rerio	65.71	0.00e+00	1348.00
IUUC-Dno-029668	Dasypus novemcinctus	96.61	0.00e+00	1864.00
IUUC-Dor-030404	Dipodomys ordii	90.96	0.00e+00	1771.00
IUUC-Dse-031345	Dothistroma septosporum	33.59	2.00e-121	430.00
IUUC-Dme-031711	Drosophila melanogaster	34.32	2.00e-147	516.00
IUUC-Ete-032308	Echinops telfairi	90.15	0.00e+00	914.00
IUUC-Eca-033637	Equus caballus	97.23	0.00e+00	1891.00
IUUC-Eeu-035151	Erinaceus europaeus	95.55	0.00e+00	1384.00
IUUC-Fca-035585	Felis catus	96.92	0.00e+00	1864.00
IUUC-Fal-037122	Ficedula albicollis	72.20	0.00e+00	1480.00
IUUC-Fox-038030	Fusarium oxysporum	33.33	5.00e-121	429.00
IUUC-Fso-038426	Fusarium solani	33.47	6.00e-126	445.00
IUUC-Gmo-038784	Gadus morhua	66.12	0.00e+00	1311.00
IUUC-Ggr-039973	Gaeumannomyces graminis	33.91	3.00e-122	432.00
IUUC-Gga-040692	Gallus gallus	73.82	0.00e+00	1507.00
IUUC-Gac-041868	Gasterosteus aculeatus	65.82	0.00e+00	1310.00
IUUC-Gma-044274	Glycine max	33.91	4.00e-136	479.00
IUUC-Ggo-045053	Gorilla gorilla	99.49	0.00e+00	1919.00
IUUC-Hsa-046635	Homo sapiens	99.69	0.00e+00	1920.00
IUUC-Hvu-047361	Hordeum vulgare	33.71	3.00e-126	446.00
IUUC-Itr-048868	Ictidomys tridecemlineatus	97.02	0.00e+00	1866.00
IUUC-Kpa-049270	Komagataella pastoris	24.48	2.00e-78	286.00
IUUC-Lch-050188	Latimeria chalumnae	68.65	0.00e+00	1226.00
IUUC-Lpe-051026	Leersia perrieri	34.77	2.00e-132	466.00
IUUC-Loc-051821	Lepisosteus oculatus	66.80	0.00e+00	1335.00
IUUC-Lma-053178	Leptosphaeria maculans	36.20	7.00e-100	357.00
IUUC-Laf-053552	Loxodonta africana	96.71	0.00e+00	1870.00
IUUC-Mcc-054667	Macaca mulatta	99.38	0.00e+00	1914.00
IUUC-Meu-056422	Macropus eugenii	92.16	0.00e+00	862.00
IUUC-Mor-056981	Magnaporthe oryzae	33.09	2.00e-120	427.00
IUUC-Mtr-058703	Medicago truncatula	33.57	6.00e-132	465.00
IUUC-Mla-059088	Melampsora laricipopulina	34.22	4.00e-91	328.00
IUUC-Mga-059798	Meleagris gallopavo	73.51	0.00e+00	1501.00
IUUC-Mvi-060404	Microbotryum violaceum	33.57	7.00e-120	425.00
IUUC-Mmr-061630	Microcebus murinus	98.15	0.00e+00	1891.00
IUUC-Mdo-062354	Monodelphis domestica	92.60	0.00e+00	1826.00
IUUC-Mmu-063199	Mus musculus	95.48	0.00e+00	1866.00
IUUC-Mac-065595	Musa acuminata	35.84	1.00e-113	404.00
IUUC-Mpu-066596	Mustela putorius furo	96.61	0.00e+00	1886.00
IUUC-Mlu-067455	Myotis lucifugus	96.71	0.00e+00	1862.00
IUUC-Nfi-068565	Neosartorya fischeri	32.58	7.00e-115	408.00
IUUC-Ncr-068748	Neurospora crassa	33.50	2.00e-125	443.00
IUUC-Nle-068979	Nomascus leucogenys	99.19	0.00e+00	1720.00
IUUC-Opr-070711	Ochotona princeps	95.38	0.00e+00	1858.00
IUUC-Ont-072603	Oreochromis niloticus	65.72	0.00e+00	1332.00
IUUC-Oan-073136	Ornithorhynchus anatinus	84.73	0.00e+00	819.00
IUUC-Ocu-074496	Oryctolagus cuniculus	96.71	0.00e+00	1873.00
IUUC-Oba-075933	Oryza barthii	33.00	8.00e-111	395.00
IUUC-Obr-076290	Oryza brachyantha	33.78	4.00e-132	465.00
IUUC-Ogu-078728	Oryza glumaepatula	33.00	6.00e-111	395.00
IUUC-Oin-079954	Oryza indica	33.37	3.00e-123	436.00
IUUC-Olo-081033	Oryza longistaminata	32.03	2.00e-105	377.00
IUUC-Ome-081797	Oryza meridionalis	32.79	9.00e-118	418.00
IUUC-Oni-082802	Oryza nivara	33.00	6.00e-111	395.00
IUUC-Opu-083595	Oryza punctata	34.70	2.00e-131	463.00
IUUC-Oru-084199	Oryza rufipogon	33.00	6.00e-111	395.00
IUUC-Osa-085349	Oryza sativa	33.88	2.00e-131	462.00
IUUC-Ola-087482	Oryzias latipes	65.62	0.00e+00	1316.00
IUUC-Olu-087797	Ostreococcus lucimarinus	25.19	2.00e-63	237.00
IUUC-Oga-088817	Otolemur garnettii	97.33	0.00e+00	1914.00
IUUC-Oar-090350	Ovis aries	94.23	0.00e+00	1441.00
IUUC-Pan-092704	Papio anubis	99.38	0.00e+00	1914.00
IUUC-Psi-093529	Pelodiscus sinensis	73.41	0.00e+00	1472.00
IUUC-Pma-094400	Petromyzon marinus	56.22	0.00e+00	1089.00
IUUC-Pno-094875	Phaeosphaeria nodorum	33.09	1.00e-118	421.00
IUUC-Ppa-095231	Physcomitrella patens	33.33	4.00e-132	466.00
IUUC-Pfo-096967	Poecilia formosa	65.01	0.00e+00	1317.00
IUUC-Pab-098300	Pongo abelii	99.38	0.00e+00	1912.00
IUUC-Pop-098966	Populus trichocarpa	34.17	3.00e-140	492.00
IUUC-Pca-100643	Procavia capensis	95.22	0.00e+00	1774.00
IUUC-Ppe-101589	Prunus persica	33.40	2.00e-135	477.00
IUUC-Pva-102766	Pteropus vampyrus	96.61	0.00e+00	1823.00
IUUC-Pgr-103330	Puccinia graminis	30.15	3.00e-105	377.00
IUUC-Ptt-103809	Puccinia triticina	31.32	7.00e-89	322.00
IUUC-Pte-104319	Pyrenophora teres	32.64	9.00e-118	417.00
IUUC-Pyt-104798	Pyrenophora triticirepentis	31.50	3.00e-105	376.00
IUUC-Rno-105817	Rattus norvegicus	94.86	0.00e+00	1858.00
IUUC-Sce-106255	Saccharomyces cerevisiae	23.05	3.00e-44	173.00
IUUC-Sha-107479	Sarcophilus harrisii	92.75	0.00e+00	1818.00
IUUC-Sja-107976	Schizosaccharomyces japonicus	24.83	1.00e-68	254.00
IUUC-Spo-108146	Schizosaccharomyces pombe	26.71	5.00e-73	269.00
IUUC-Ssl-108663	Sclerotinia sclerotiorum	33.60	2.00e-110	393.00
IUUC-Smo-109585	Selaginella moellendorffii	34.64	3.00e-124	439.00
IUUC-Sit-110275	Setaria italica	34.60	1.00e-130	460.00
IUUC-Sly-111073	Solanum lycopersicum	34.22	1.00e-134	474.00
IUUC-Stu-112392	Solanum tuberosum	27.62	5.00e-14	70.90
IUUC-Sar-113718	Sorex araneus	92.71	0.00e+00	1778.00
IUUC-Sbi-114080	Sorghum bicolor	34.70	6.00e-136	478.00
IUUC-Sre-115160	Sporisorium reilianum	31.87	2.00e-123	437.00
IUUC-Ssc-115997	Sus scrofa	96.09	0.00e+00	1867.00
IUUC-Tgu-116904	Taeniopygia guttata	73.33	0.00e+00	1340.00
IUUC-Tru-117946	Takifugu rubripes	64.70	0.00e+00	1315.00
IUUC-Tni-119692	Tetraodon nigroviridis	65.01	0.00e+00	1314.00
IUUC-Tca-121455	Theobroma cacao	34.01	6.00e-138	485.00
IUUC-Tre-122128	Trichoderma reesei	32.38	2.00e-122	433.00
IUUC-Tvi-122657	Trichoderma virens	33.16	1.00e-124	440.00
IUUC-Tae-125953	Triticum aestivum	34.26	8.00e-128	451.00
IUUC-Tur-126110	Triticum urartu	30.62	2.00e-94	340.00
IUUC-Tme-127173	Tuber melanosporum	30.38	5.00e-103	369.00
IUUC-Ttr-128420	Tursiops truncatus	96.71	0.00e+00	1863.00
IUUC-Uma-129580	Ustilago maydis	31.54	1.00e-122	434.00
IUUC-Vda-129790	Verticillium dahliae	31.10	8.00e-111	394.00
IUUC-Vvi-131095	Vitis vinifera	33.16	5.00e-132	465.00
IUUC-Xtr-131906	Xenopus tropicalis	68.75	0.00e+00	1369.00
IUUC-Xma-134197	Xiphophorus maculatus	65.41	0.00e+00	1319.00
IUUC-Yli-134617	Yarrowia lipolytica	28.41	5.00e-96	345.00
IUUC-Zma-134979	Zea mays	32.37	2.00e-103	370.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence