iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bol-015851

Ensembl Protein ID

Bo1g008280.1

UniProt Accession

A0A0D3A2A2; A0A0D3A2A2_BRAOL

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bo1g008280	Bo1g008280.1	Bo1g008280.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	7.50e-126	421.0	129	435
E3 adaptor/Cullin RING/DCX/DWD	1.50e-28	99.1	264	294
UBD/Beta-Prp	4.20e-40	139.3	161	302

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 2    ekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkkvrtl.tghs 96
           e+ ldap++ ddfylnLldW+s nvla+aLg++vylw+a++g+ s+l  + eek  vts++w ++g ++avG +++ev+++D ++++++rtl  gh+
   Q: 129  ERTLDAPDIVDDFYLNLLDWGSANVLAIALGHTVYLWDASSGSTSELVTIdEEKGPVTSINWAPDGRHVAVGLNNSEVQLWDSASNRQLRTLkGGHQ 225
           689***********************************************888999************************************778** PP
   S: 97   arvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse......Plkkfkehkaavkaiaw 187
           +rvg+++Wn+++l++G+ dg+i+ +dvr++ + ++t+++h+qevCGlkw+ ++++LasGGnDn+v++wd s  +       l++ +eh++avka+aw
   Q: 226  SRVGSMAWNNHILTTGGMDGQIVNNDVRIRSHVVETYRGHTQEVCGLKWSGSGQQLASGGNDNVVHIWDRSVASsnsttqYLHRLEEHTSAVKALAW 322
           *********************************************************************87555455666788899*********** PP
   S: 188  sPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgheaRvlslalspdgeaivt 284
           +P+q +lLa+GGG  Dr+ikfwnt tga+l+++dtgsqvcsllwsk+++el+s+hGf++n++tlwkyps+ k+ael+gh++Rvl++a spdg +++t
   Q: 323  CPFQANLLATGGGGGDRTIKFWNTHTGACLNSVDTGSQVCSLLWSKNERELLSSHGFTQNQLTLWKYPSMVKMAELTGHTSRVLYMAQSPDGCTVAT 419
           ************************************************************************************************* PP
   S: 285  aagDetlrfwklfdkk 300
           aagDetlrfw++f   
   Q: 420  AAGDETLRFWNVFGVP 435
           *************765 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWD 29
           gHt +v++l++  s+  l+sG++D+++++WD
   Q: 264  GHTQEVCGLKWsgSGQQLASGGNDNVVHIWD 294
           8**********976699************** PP

UBD/Beta-Prp

   S: 117  tirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq.t 211
           t+ +wd ++g+ +e  t ++++g v+++++ pdg+ ++ G +++ v+lWd+++++ lrtl+ggh+++v s++++     l +g++dg++   d++ +
   Q: 161  TVYLWDASSGSTSELvTIDEEKGPVTSINWAPDGRHVAVGLNNSEVQLWDSASNRQLRTLKGGHQSRVGSMAWNN--HILTTGGMDGQIVNNDVRiR 255
           8999*****99887679999*****************************************************99..89****************** PP
   S: 212  gecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllk 258
           +++v+t++ght+ v+ ++ s  ++ l+sg+ D+++ iWd      ++
   Q: 256  SHVVETYRGHTQEVCGLKWSGSGQQLASGGNDNVVHIWDRSVASSNS 302
           **************************************966555544 PP

Organism

Brassica oleracea

Protein Sequence
(Fasta)

MDAGMNTSTH LKAQARCPLQ EHFLPRKSSK ENLDRFIPNR SAMDFDYAHY ALTEGRNGKD 60
QATAAVSSPS REAYRKQLAE TMNLNHTRIL AFRNKPQAPV ELLPTDHSAS LHQQPRSVKP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGCAG GTATGAACAC ATCTACGCAC TTGAAGGCTC AAGCTCGTTG CCCTCTTCAA 60
GAACACTTCC TTCCCAGGAA GAGTTCCAAG GAAAACGTAA GTTTGCTCAG ATTCGATACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bra-016738	Brassica rapa	97.59	0.00e+00	915.00
IUUC-Dse-031391	Dothistroma septosporum	49.47	2.00e-97	349.00
IUUC-Fso-038375	Fusarium solani	48.80	1.00e-95	343.00
IUUC-Gac-041431	Gasterosteus aculeatus	43.60	2.00e-97	348.00
IUUC-Lma-052998	Leptosphaeria maculans	47.86	1.00e-95	343.00
IUUC-Ola-086907	Oryzias latipes	46.52	5.00e-100	357.00
IUUC-Olu-087647	Ostreococcus lucimarinus	55.53	2.00e-134	472.00
IUUC-Pno-094809	Phaeosphaeria nodorum	48.25	3.00e-96	345.00
IUUC-Pte-104142	Pyrenophora teres	47.75	6.00e-96	344.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	47.75	6.00e-96	344.00
IUUC-Sit-110032	Setaria italica	69.41	0.00e+00	651.00
IUUC-Sly-111202	Solanum lycopersicum	80.18	0.00e+00	743.00
IUUC-Tru-118184	Takifugu rubripes	43.10	2.00e-89	322.00
IUUC-Tni-120474	Tetraodon nigroviridis	44.53	2.00e-94	339.00
IUUC-Tvi-122531	Trichoderma virens	48.79	8.00e-96	344.00
IUUC-Vvi-131245	Vitis vinifera	79.26	0.00e+00	696.00
IUUC-Xma-133332	Xiphophorus maculatus	47.01	3.00e-102	365.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence