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Tag Content
iUUCD ID IUUC-Psi-093830
Ensembl Protein ID ENSPSIP00000016638.1
UniProt Accession K7G8M7; K7G8M7_PELSI
Genbank Protein ID ENSPSIP00000016638
Protein Name Katanin p80 WD40 repeat-containing subunit B1; p80 katanin
Genbank Nucleotide ID AGCU01119620
Gene Name KATNB1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPSIG00000014651.1 ENSPSIT00000016708.1 ENSPSIP00000016632.1
ENSPSIG00000014651.1 ENSPSIT00000016714.1 ENSPSIP00000016638.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 4.20e-41 137.2 145 181
UBD/Beta-Prp 1.20e-60 205.2 15 252
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gHt  v+cl+f +d + ++s++ D+t+k+WDl+ g+l
   Q: 145  GHTQAVRCLRFsPDgKWIASAAEDHTVKLWDLTAGKL 181
           8***********999******************9986 PP
   

   UBD/Beta-Prp
   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           ++ +h ++v + v  + +++llatg++d ++ +w+v +++++ slsgh+ +v +v+++ +++++v+gs+ + i+vwdl++ k++++l g
   Q: 15   EITAHSSNVSSLVLGKSSGRLLATGGDDCRVNLWSVNKPNCIMSLSGHTTPVESVRINTNEELIVSGSQSGSIRVWDLEAAKILRILMG 103
           34445555555555555666666666666666666666666666666666666666666666666666666666666666666666666 PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtd 181
           h+++++sl+f+p g+ + sG  d  i++wd++ + c+  t +gh+++v+c++++pdg+ ++s++ D tv+lWdl  gkl+ ++tg ht+
   Q: 104  HKANICSLDFHPFGSLVTSGALDTNIKLWDVRRKGCVF-TYKGHTQAVRCLRFSPDGKWIASAAEDHTVKLWDLTAGKLMFEFTG-HTG 190
           66666666666655666666666666666666666665.6666666666666666666666666666666666666666666665.666 PP
   S: 182  svyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssD 243
           +v+ ++f++n   l+sgs d+tv++wdl++ ++v   ++  ++v++v f p++  l+sg +D
   Q: 191  PVNIVEFHPNEYLLASGSSDRTVRFWDLEKFQVVSCIEEEATPVRCVLFNPDGCCLYSGYQD 252
           66666666666666666666666666666666666666666666666666666666665544 PP
   
Organism Pelodiscus sinensis
Functional Description
(View)

Functional Description


     Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
 Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
Protein Sequence
(Fasta)
MATSVATKTA WKLQEITAHS SNVSSLVLGK SSGRLLATGG DDCRVNLWSV NKPNCIMSLS 60
GHTTPVESVR INTNEELIVS GSQSGSIRVW DLEAAKILRI LMGHKANICS LDFHPFGSLV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Psi-093830|E3,WD_repeat;UBD,Beta-Prp|Pelodiscus sinensis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCAAACGTCA CACTGATACA GATCAAGAAG ACTAAGTCAG AACTCAAGAT CTGTCCTGTT 60
GATGGGAGGA AACTGGCCAC TGTTCCAGAT ACAACAGAAT AAGAATTTTG AAAGGAATTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Psi-093830|E3,WD_repeat;UBD,Beta-Prp|Pelodiscus sinensis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR026962--Katanin_bsu1
IPR028021--Katanin_C-terminal
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF13925--Katanin_con80
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030424--C:axon
GO:0005813--C:centrosome
GO:0005829--C:cytosol
GO:0008352--C:katanin complex
GO:0005874--C:microtubule
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0000922--C:spindle pole
GO:0008568--F:microtubule-severing ATPase activity
GO:0051301--P:cell division
GO:0051013--P:microtubule severing
GO:0007067--P:mitotic nuclear division
GO:0007026--P:negative regulation of microtubule depolymerization
GO:0031117--P:positive regulation of microtubule depolymerization
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000954 Aegilops tauschii 45.54 4.00e-85 310.00
IUUC-Aml-002187 Ailuropoda melanoleuca 76.29 0.00e+00 951.00
IUUC-Atr-002899 Amborella trichopoda 53.82 5.00e-102 365.00
IUUC-Apl-003305 Anas platyrhynchos 84.09 0.00e+00 1099.00
IUUC-Aca-004635 Anolis carolinensis 84.23 0.00e+00 1011.00
IUUC-Aly-005711 Arabidopsis lyrata 51.50 3.00e-101 362.00
IUUC-Ath-007606 Arabidopsis thaliana 51.50 3.00e-101 362.00
IUUC-Ame-010870 Astyanax mexicanus 58.82 1.00e-100 359.00
IUUC-Bta-012527 Bos taurus 81.00 0.00e+00 1033.00
IUUC-Bdi-014652 Brachypodium distachyon 52.84 2.00e-102 367.00
IUUC-Bol-015242 Brassica oleracea 50.50 1.00e-99 357.00
IUUC-Bra-017390 Brassica rapa 50.83 7.00e-100 358.00
IUUC-Cja-019706 Callithrix jacchus 80.03 0.00e+00 958.00
IUUC-Cfa-020139 Canis familiaris 66.79 0.00e+00 649.00
IUUC-Cpo-021710 Cavia porcellus 81.09 0.00e+00 1019.00
IUUC-Cre-022746 Chlamydomonas reinhardtii 41.83 3.00e-69 256.00
IUUC-Csa-023546 Chlorocebus sabaeus 80.79 0.00e+00 932.00
IUUC-Cin-025156 Ciona intestinalis 42.62 4.00e-155 541.00
IUUC-Csv-025962 Ciona savignyi 48.30 2.00e-87 315.00
IUUC-Dre-028215 Danio rerio 61.54 0.00e+00 833.00
IUUC-Dno-029314 Dasypus novemcinctus 80.48 0.00e+00 973.00
IUUC-Dor-030482 Dipodomys ordii 80.79 0.00e+00 1041.00
IUUC-Dme-032188 Drosophila melanogaster 39.60 2.00e-59 223.00
IUUC-Eca-034143 Equus caballus 80.33 0.00e+00 1010.00
IUUC-Fca-035924 Felis catus 81.09 0.00e+00 1008.00
IUUC-Fal-037387 Ficedula albicollis 84.72 0.00e+00 1079.00
IUUC-Gmo-038692 Gadus morhua 63.70 4.00e-152 531.00
IUUC-Gga-040597 Gallus gallus 84.09 0.00e+00 1116.00
IUUC-Gac-042004 Gasterosteus aculeatus 60.72 0.00e+00 811.00
IUUC-Gma-044134 Glycine max 52.16 7.00e-100 358.00
IUUC-Ggo-044761 Gorilla gorilla 80.79 0.00e+00 952.00
IUUC-Hsa-045698 Homo sapiens 81.69 0.00e+00 977.00
IUUC-Hvu-047649 Hordeum vulgare 50.97 3.00e-102 365.00
IUUC-Itr-048697 Ictidomys tridecemlineatus 81.09 0.00e+00 996.00
IUUC-Lch-049674 Latimeria chalumnae 68.38 0.00e+00 929.00
IUUC-Lpe-051597 Leersia perrieri 47.00 3.00e-92 332.00
IUUC-Loc-052623 Lepisosteus oculatus 66.19 0.00e+00 903.00
IUUC-Laf-054587 Loxodonta africana 81.54 0.00e+00 1028.00
IUUC-Mcc-055851 Macaca mulatta 80.79 0.00e+00 952.00
IUUC-Meu-056704 Macropus eugenii 82.58 0.00e+00 1094.00
IUUC-Mtr-058053 Medicago truncatula 51.83 4.00e-103 369.00
IUUC-Mga-059608 Meleagris gallopavo 84.71 0.00e+00 1110.00
IUUC-Mmr-061154 Microcebus murinus 80.66 0.00e+00 977.00
IUUC-Mdo-062365 Monodelphis domestica 78.67 0.00e+00 1028.00
IUUC-Mmu-063754 Mus musculus 80.87 0.00e+00 1005.00
IUUC-Mac-064667 Musa acuminata 52.56 9.00e-100 357.00
IUUC-Mpu-066245 Mustela putorius furo 80.33 0.00e+00 971.00
IUUC-Mlu-067692 Myotis lucifugus 80.89 0.00e+00 995.00
IUUC-Nle-070051 Nomascus leucogenys 79.34 0.00e+00 945.00
IUUC-Opr-070855 Ochotona princeps 80.64 0.00e+00 1001.00
IUUC-Ont-071883 Oreochromis niloticus 59.05 0.00e+00 827.00
IUUC-Oan-073293 Ornithorhynchus anatinus 82.33 0.00e+00 965.00
IUUC-Ocu-074644 Oryctolagus cuniculus 81.54 0.00e+00 1016.00
IUUC-Oba-075448 Oryza barthii 53.55 1.00e-105 377.00
IUUC-Obr-076385 Oryza brachyantha 53.85 1.00e-104 374.00
IUUC-Ogl-077427 Oryza glaberrima 54.52 1.00e-105 377.00
IUUC-Ogu-079022 Oryza glumaepatula 48.87 2.00e-96 347.00
IUUC-Oin-079811 Oryza indica 52.09 2.00e-102 367.00
IUUC-Olo-080245 Oryza longistaminata 52.09 2.00e-102 367.00
IUUC-Ome-081239 Oryza meridionalis 53.36 5.00e-102 365.00
IUUC-Oni-082640 Oryza nivara 53.55 1.00e-105 377.00
IUUC-Opu-083748 Oryza punctata 54.18 5.00e-105 375.00
IUUC-Oru-084609 Oryza rufipogon 53.55 1.00e-105 377.00
IUUC-Osa-086267 Oryza sativa 48.87 2.00e-96 347.00
IUUC-Ola-087483 Oryzias latipes 54.96 1.00e-180 625.00
IUUC-Oga-087964 Otolemur garnettii 81.42 0.00e+00 1025.00
IUUC-Oar-089483 Ovis aries 79.64 0.00e+00 983.00
IUUC-Ptr-091387 Pan troglodytes 81.85 0.00e+00 978.00
IUUC-Pan-092623 Papio anubis 80.79 0.00e+00 952.00
IUUC-Pma-094135 Petromyzon marinus 46.08 4.00e-41 160.00
IUUC-Ppa-095379 Physcomitrella patens 54.15 3.00e-98 352.00
IUUC-Pfo-096755 Poecilia formosa 57.68 0.00e+00 812.00
IUUC-Pab-097564 Pongo abelii 78.95 0.00e+00 827.00
IUUC-Pop-099149 Populus trichocarpa 53.16 5.00e-105 375.00
IUUC-Pca-100357 Procavia capensis 86.67 1.00e-112 399.00
IUUC-Ppe-101237 Prunus persica 52.49 3.00e-103 369.00
IUUC-Pva-102397 Pteropus vampyrus 76.59 0.00e+00 929.00
IUUC-Rno-105349 Rattus norvegicus 80.94 0.00e+00 1037.00
IUUC-Smo-109558 Selaginella moellendorffii 33.43 3.00e-106 379.00
IUUC-Sit-110360 Setaria italica 54.52 4.00e-105 375.00
IUUC-Sly-111307 Solanum lycopersicum 53.18 1.00e-100 360.00
IUUC-Stu-112462 Solanum tuberosum 52.40 6.00e-97 347.00
IUUC-Sar-112953 Sorex araneus 70.61 1.00e-91 330.00
IUUC-Sbi-114389 Sorghum bicolor 46.58 8.00e-93 334.00
IUUC-Ssc-115949 Sus scrofa 78.74 0.00e+00 746.00
IUUC-Tgu-117461 Taeniopygia guttata 85.11 0.00e+00 1112.00
IUUC-Tru-117865 Takifugu rubripes 59.49 0.00e+00 807.00
IUUC-Tsy-119036 Tarsius syrichta 85.04 1.00e-60 226.00
IUUC-Tni-120903 Tetraodon nigroviridis 61.14 0.00e+00 784.00
IUUC-Tca-121185 Theobroma cacao 52.16 2.00e-102 367.00
IUUC-Tae-125307 Triticum aestivum 51.61 3.00e-103 369.00
IUUC-Tur-126181 Triticum urartu 47.85 2.00e-92 333.00
IUUC-Tbe-127518 Tupaia belangeri 68.36 9.00e-155 540.00
IUUC-Ttr-128172 Tursiops truncatus 79.58 0.00e+00 984.00
IUUC-Vvi-131489 Vitis vinifera 53.49 8.00e-105 374.00
IUUC-Xtr-132915 Xenopus tropicalis 71.28 0.00e+00 946.00
IUUC-Xma-134133 Xiphophorus maculatus 57.25 0.00e+00 800.00
Created Date 25-Jun-2017

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