iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afu-009065

Ensembl Protein ID

CADAFUAP00003933

UniProt Accession

Q4WZU2; Q4WZU2_ASPFU

Genbank Protein ID

EAL93873.1

Protein Name

Poly(A)+ RNA transport protein (UbaA), putative

Genbank Nucleotide ID

AAHF01000001

Gene Name

AFUA_2G15760

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADAFUAG00003933	CADAFUAT00003933	CADAFUAP00003933

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.80e-197	655.5	417	903

Active Site

Position(s)	Description	Evidence
600	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdv 88
           YD+Qi+++G e q+k+ +   +lvGag++GcE+lKn +++G+     g+i v+Dmd++e snlnrqFLfr +dvgk K+e+a +a++ +npd 
   Q: 417  YDGQIAVFGKEFQDKIANLTQFLVGAGAIGCETLKNWAMMGLgtgpkGKIFVTDMDQIERSNLNRQFLFRSKDVGKLKSECASAAAQAMNPDL 509
           ********************************************************************************************* PP
   S: 89   nveahe..esiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctl 176
           ++++++  +++ +++e+i+   F + +d+V +aldn++ar++v+r+c+  r+pl+esgtlG++G+++vi++++te+ys+s+dpp+k++P+ctl
   Q: 510  KGKIVTlrDRVGPDTEHIFneeFWEALDGVTNALDNVDARTYVDRRCVFFRKPLLESGTLGTKGNTQVILPHITESYSSSQDPPEKSFPMCTL 602
           9988763378*******9999************************************************************************ PP
   S: 177  ketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqll 257
           k++pn +ehti wa            + +n++l++ +  e++l++  + + +++++  ++ l+++++ +f+++i +a+++f+ +++n i+qll
   Q: 603  KSFPNRIEHTIAWArdlfqtffvgppEAVNMYLSQPNYIEQTLKQ--AGNEKQTLEHLRDFLVTNKPTSFDDCIIWARQQFEAQYNNAIQQLL 693
           **************************9999999887777777764..3445555555556799999*************************** PP
   S: 258  ksfecdivtkskspfwv............................................................sfcsnaealqvpekve 290
            +f+ d  t+s++pfw+                                                            s ++ ++  ++p+ ++
   Q: 694  YNFPRDSKTSSGQPFWSgpkraptplkfdssnpthlafivaganlhafnygiknpgvdkeyyrkvvdnmiipefvprSGVKIQADENEPDPNA 786
           ************************************************************************999998899999999999999 PP
   S: 291  kdeevvkasaplylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaa 381
           ++   +++s++++ l+++l   e+  g   + ++fekddd   ++d++taa+nlra +++i++ +d++++k iag+iipaiatt+a v Gl+a
   Q: 787  QQSSSLDDSQEIQRLVESLPPPESLGGFRLNPVEFEKDDDTnhHIDFITAASNLRADNYDIPQ-ADRHKTKFIAGKIIPAIATTTALVTGLVA 878
           99999999999*****************************999********************.***************************** PP
   S: 382  qEviKvvsg..kfeplknfflfdae 404
           +E++K+++g  + e++kn f+++a+
   Q: 879  LELYKIIDGkdDIEQYKNGFVNLAL 903
           *********777889*****99875 PP

Organism

Aspergillus fumigatus

Protein Sequence
(Fasta)

MQLDNPQETV EKIKQGEIDE SLYSRQLYVL GHEAMKRMSS SNVLVVGMKG LGVEIAKNVA 60
LAGVKSLTLY DPAPVVISDL SSQFFLQPQD VGKPRAEVTA PRVAELNSYV PVTVHKGSNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGCTTG ATAACCCCCA GGAAACAGTG GAGAAGATCA AACAGGGAGA GATCGATGAG 60
TCCCTGTACA GTCGTCAACT GTATGTTGAT CCCATTCCGC TTTAATGTAA TATTCTAATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004839--F:ubiquitin activating enzyme activity

KEGG

afm:AFUA_2G15760

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000367	Aegilops tauschii	45.98	0.00e+00	816.00
IUUC-Aml-001311	Ailuropoda melanoleuca	53.27	0.00e+00	1082.00
IUUC-Atr-002684	Amborella trichopoda	44.62	0.00e+00	842.00
IUUC-Apl-004158	Anas platyrhynchos	43.90	0.00e+00	704.00
IUUC-Aca-004620	Anolis carolinensis	55.18	0.00e+00	1097.00
IUUC-Aly-005418	Arabidopsis lyrata	45.73	0.00e+00	870.00
IUUC-Ath-006891	Arabidopsis thaliana	44.85	0.00e+00	860.00
IUUC-Ago-007873	Ashbya gossypii	60.88	0.00e+00	1209.00
IUUC-Acl-008181	Aspergillus clavatus	93.48	0.00e+00	1954.00
IUUC-Afl-008455	Aspergillus flavus	90.18	0.00e+00	1830.00
IUUC-Ani-009371	Aspergillus nidulans	88.80	0.00e+00	1828.00
IUUC-Ang-009737	Aspergillus niger	89.50	0.00e+00	1891.00
IUUC-Aor-010007	Aspergillus oryzae	90.18	0.00e+00	1828.00
IUUC-Ate-010466	Aspergillus terreus	89.76	0.00e+00	1933.00
IUUC-Ame-010933	Astyanax mexicanus	55.00	0.00e+00	1047.00
IUUC-Bgr-012281	Blumeria graminis	69.53	0.00e+00	1478.00
IUUC-Bta-012767	Bos taurus	53.65	0.00e+00	1096.00
IUUC-Bci-013721	Botrytis cinerea	73.03	0.00e+00	1488.00
IUUC-Bdi-014009	Brachypodium distachyon	43.90	0.00e+00	837.00
IUUC-Bol-015665	Brassica oleracea	45.75	0.00e+00	866.00
IUUC-Bra-017252	Brassica rapa	45.33	0.00e+00	869.00
IUUC-Cel-018260	Caenorhabditis elegans	46.45	0.00e+00	835.00
IUUC-Cja-019152	Callithrix jacchus	53.10	0.00e+00	1083.00
IUUC-Cfa-020622	Canis familiaris	52.30	0.00e+00	1031.00
IUUC-Cpo-022526	Cavia porcellus	53.57	0.00e+00	1072.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	44.39	0.00e+00	798.00
IUUC-Csa-023780	Chlorocebus sabaeus	53.76	0.00e+00	1084.00
IUUC-Cho-024682	Choloepus hoffmanni	41.84	8.00e-98	350.00
IUUC-Cin-025790	Ciona intestinalis	53.52	0.00e+00	1081.00
IUUC-Csv-026084	Ciona savignyi	53.56	0.00e+00	1076.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	71.24	0.00e+00	1533.00
IUUC-Cne-026960	Cryptococcus neoformans	61.56	0.00e+00	1247.00
IUUC-Cme-027290	Cyanidioschyzon merolae	44.67	0.00e+00	854.00
IUUC-Dre-028149	Danio rerio	55.27	0.00e+00	1075.00
IUUC-Dno-028884	Dasypus novemcinctus	53.67	0.00e+00	1088.00
IUUC-Dor-030229	Dipodomys ordii	51.32	0.00e+00	1022.00
IUUC-Dse-031524	Dothistroma septosporum	73.82	0.00e+00	1555.00
IUUC-Dme-032045	Drosophila melanogaster	51.87	0.00e+00	1027.00
IUUC-Ete-033124	Echinops telfairi	42.98	2.00e-150	525.00
IUUC-Eca-033330	Equus caballus	53.57	0.00e+00	1083.00
IUUC-Eeu-035323	Erinaceus europaeus	43.97	5.00e-155	540.00
IUUC-Fca-036255	Felis catus	53.86	0.00e+00	1085.00
IUUC-Fal-036848	Ficedula albicollis	44.10	0.00e+00	717.00
IUUC-Fox-038007	Fusarium oxysporum	69.69	0.00e+00	793.00
IUUC-Fso-038339	Fusarium solani	70.30	0.00e+00	1453.00
IUUC-Gmo-039338	Gadus morhua	53.76	0.00e+00	1044.00
IUUC-Ggr-039823	Gaeumannomyces graminis	69.91	0.00e+00	1533.00
IUUC-Gga-040747	Gallus gallus	43.86	0.00e+00	707.00
IUUC-Gac-041773	Gasterosteus aculeatus	53.03	0.00e+00	1028.00
IUUC-Gma-043198	Glycine max	45.90	0.00e+00	866.00
IUUC-Ggo-045336	Gorilla gorilla	53.76	0.00e+00	1070.00
IUUC-Hsa-045982	Homo sapiens	53.86	0.00e+00	1071.00
IUUC-Hvu-047418	Hordeum vulgare	45.74	0.00e+00	848.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	54.06	0.00e+00	1091.00
IUUC-Kpa-049112	Komagataella pastoris	60.64	0.00e+00	1200.00
IUUC-Lch-050371	Latimeria chalumnae	55.47	0.00e+00	1087.00
IUUC-Lpe-051299	Leersia perrieri	44.17	0.00e+00	863.00
IUUC-Loc-052936	Lepisosteus oculatus	55.08	0.00e+00	1080.00
IUUC-Lma-053315	Leptosphaeria maculans	74.13	0.00e+00	1615.00
IUUC-Laf-053948	Loxodonta africana	52.98	0.00e+00	1049.00
IUUC-Mcc-055843	Macaca mulatta	53.76	0.00e+00	1087.00
IUUC-Meu-056258	Macropus eugenii	53.47	0.00e+00	1065.00
IUUC-Mor-057269	Magnaporthe oryzae	70.14	0.00e+00	1504.00
IUUC-Mpo-057435	Magnaporthe poae	69.83	0.00e+00	1486.00
IUUC-Mtr-058572	Medicago truncatula	45.46	0.00e+00	854.00
IUUC-Mla-059176	Melampsora laricipopulina	59.42	0.00e+00	1169.00
IUUC-Mga-059721	Meleagris gallopavo	43.40	0.00e+00	682.00
IUUC-Mvi-060437	Microbotryum violaceum	56.96	0.00e+00	1153.00
IUUC-Mmr-061405	Microcebus murinus	52.69	0.00e+00	1049.00
IUUC-Mdo-062032	Monodelphis domestica	52.27	0.00e+00	1035.00
IUUC-Mmu-063280	Mus musculus	53.37	0.00e+00	1074.00
IUUC-Mac-065505	Musa acuminata	46.18	0.00e+00	867.00
IUUC-Mpu-066409	Mustela putorius furo	53.57	0.00e+00	1088.00
IUUC-Mlu-067217	Myotis lucifugus	53.86	0.00e+00	1079.00
IUUC-Nfi-068407	Neosartorya fischeri	98.35	0.00e+00	2036.00
IUUC-Ncr-068698	Neurospora crassa	70.55	0.00e+00	1480.00
IUUC-Nle-070072	Nomascus leucogenys	50.93	0.00e+00	988.00
IUUC-Opr-070715	Ochotona princeps	37.65	9.00e-179	619.00
IUUC-Ont-071671	Oreochromis niloticus	55.27	0.00e+00	1063.00
IUUC-Oan-073268	Ornithorhynchus anatinus	43.25	0.00e+00	667.00
IUUC-Ocu-074544	Oryctolagus cuniculus	54.15	0.00e+00	1097.00
IUUC-Oba-075120	Oryza barthii	44.62	0.00e+00	834.00
IUUC-Obr-076557	Oryza brachyantha	45.08	0.00e+00	832.00
IUUC-Ogl-077887	Oryza glaberrima	44.62	0.00e+00	833.00
IUUC-Ogu-078305	Oryza glumaepatula	44.08	0.00e+00	852.00
IUUC-Oin-080154	Oryza indica	43.98	0.00e+00	850.00
IUUC-Olo-081089	Oryza longistaminata	44.17	0.00e+00	856.00
IUUC-Ome-081942	Oryza meridionalis	44.71	0.00e+00	837.00
IUUC-Oni-082365	Oryza nivara	44.71	0.00e+00	837.00
IUUC-Opu-083977	Oryza punctata	44.42	0.00e+00	836.00
IUUC-Oru-084469	Oryza rufipogon	44.08	0.00e+00	852.00
IUUC-Osa-085949	Oryza sativa	44.81	0.00e+00	841.00
IUUC-Ola-087002	Oryzias latipes	55.08	0.00e+00	1074.00
IUUC-Olu-087687	Ostreococcus lucimarinus	44.31	0.00e+00	788.00
IUUC-Oga-088594	Otolemur garnettii	53.76	0.00e+00	1066.00
IUUC-Oar-090068	Ovis aries	53.62	0.00e+00	1090.00
IUUC-Ptr-090609	Pan troglodytes	43.66	0.00e+00	703.00
IUUC-Pan-092114	Papio anubis	53.67	0.00e+00	1085.00
IUUC-Psi-093489	Pelodiscus sinensis	44.14	0.00e+00	726.00
IUUC-Pma-094214	Petromyzon marinus	47.46	7.00e-37	144.00
IUUC-Pno-095154	Phaeosphaeria nodorum	73.77	0.00e+00	1613.00
IUUC-Ppa-095227	Physcomitrella patens	46.89	0.00e+00	877.00
IUUC-Pfo-097184	Poecilia formosa	54.44	0.00e+00	1061.00
IUUC-Pab-097861	Pongo abelii	53.57	0.00e+00	1056.00
IUUC-Pop-099577	Populus trichocarpa	45.65	0.00e+00	878.00
IUUC-Pca-100347	Procavia capensis	51.78	0.00e+00	902.00
IUUC-Ppe-102012	Prunus persica	45.11	0.00e+00	866.00
IUUC-Pva-102584	Pteropus vampyrus	53.86	0.00e+00	1120.00
IUUC-Pgr-103336	Puccinia graminis	57.80	0.00e+00	1104.00
IUUC-Ptt-103939	Puccinia triticina	57.09	0.00e+00	1097.00
IUUC-Pte-104200	Pyrenophora teres	75.10	0.00e+00	1647.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	73.85	0.00e+00	1637.00
IUUC-Rno-105462	Rattus norvegicus	53.18	0.00e+00	1070.00
IUUC-Sce-106245	Saccharomyces cerevisiae	60.62	0.00e+00	1252.00
IUUC-Sha-107142	Sarcophilus harrisii	53.57	0.00e+00	1070.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	60.53	0.00e+00	1267.00
IUUC-Spo-108034	Schizosaccharomyces pombe	61.76	0.00e+00	1267.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	73.11	0.00e+00	1509.00
IUUC-Smo-109211	Selaginella moellendorffii	47.32	0.00e+00	860.00
IUUC-Sit-110281	Setaria italica	45.31	0.00e+00	859.00
IUUC-Sly-110914	Solanum lycopersicum	45.02	0.00e+00	883.00
IUUC-Stu-112109	Solanum tuberosum	45.02	0.00e+00	887.00
IUUC-Sar-113737	Sorex araneus	53.57	0.00e+00	1086.00
IUUC-Sbi-114520	Sorghum bicolor	45.21	0.00e+00	866.00
IUUC-Sre-115148	Sporisorium reilianum	57.30	0.00e+00	1140.00
IUUC-Ssc-115777	Sus scrofa	53.52	0.00e+00	1086.00
IUUC-Tgu-116565	Taeniopygia guttata	43.74	0.00e+00	717.00
IUUC-Tru-118742	Takifugu rubripes	54.94	0.00e+00	1031.00
IUUC-Tsy-119436	Tarsius syrichta	38.20	6.00e-168	583.00
IUUC-Tni-120401	Tetraodon nigroviridis	55.08	0.00e+00	1038.00
IUUC-Tca-121672	Theobroma cacao	45.66	0.00e+00	875.00
IUUC-Tre-122009	Trichoderma reesei	69.86	0.00e+00	1426.00
IUUC-Tvi-122259	Trichoderma virens	70.61	0.00e+00	1431.00
IUUC-Tae-125676	Triticum aestivum	44.95	0.00e+00	867.00
IUUC-Tur-126189	Triticum urartu	45.88	0.00e+00	817.00
IUUC-Tme-127055	Tuber melanosporum	66.57	0.00e+00	1352.00
IUUC-Tbe-127587	Tupaia belangeri	43.95	3.00e-161	560.00
IUUC-Ttr-128331	Tursiops truncatus	53.37	0.00e+00	1074.00
IUUC-Uma-129387	Ustilago maydis	58.05	0.00e+00	1143.00
IUUC-Vda-129977	Verticillium dahliae	70.03	0.00e+00	1426.00
IUUC-Vpa-130716	Vicugna pacos	42.51	0.00e+00	686.00
IUUC-Vvi-130857	Vitis vinifera	45.34	0.00e+00	880.00
IUUC-Xtr-132026	Xenopus tropicalis	45.97	0.00e+00	796.00
IUUC-Xma-133805	Xiphophorus maculatus	54.10	0.00e+00	1044.00
IUUC-Yli-134547	Yarrowia lipolytica	59.63	0.00e+00	1254.00
IUUC-Zma-135052	Zea mays	45.23	0.00e+00	866.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence