iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bol-015884

Ensembl Protein ID

Bo1g050980.1

UniProt Accession

A0A0D3A748; A0A0D3A748_BRAOL

Protein Name

E3 ubiquitin-protein ligase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bo1g050980	Bo1g050980.1	Bo1g050980.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	34.65	1.00e-35	147.00	IUUC-Dme-031700

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Brassica oleracea

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

METDSMESST RSVQNDEIHH NGTFHFSSTK SHGGGGGASP AVVTNIVGPT ATSVYELLEC 60
PVCTCSMYPP IHQCHNGHTL CSTCKVRVHN RCPTCRQELG DIRCLALEKV AESLELPCKF 120

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Nucleotide Sequence
(Fasta)

ATGGAAACGG ATAGTATGGA ATCGTCGACG AGAAGCGTTC AGAACGATGA GATCCATCAC 60
AACGGAACTT TCCACTTCTC TTCCACCAAG AGCCACGGCG GCGGCGGAGG CGCTTCTCCC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bra-016775	Brassica rapa	99.07	0.00e+00	670.00
IUUC-Cel-018320	Caenorhabditis elegans	33.11	3.00e-37	149.00
IUUC-Dme-031700	Drosophila melanogaster	35.48	3.00e-33	135.00
IUUC-Gma-042926	Glycine max	81.61	3.00e-132	464.00
IUUC-Oan-073701	Ornithorhynchus anatinus	25.15	7.00e-12	63.90
IUUC-Ogu-078042	Oryza glumaepatula	83.59	1.00e-131	462.00
IUUC-Olo-080244	Oryza longistaminata	83.59	8.00e-132	463.00
IUUC-Sit-110245	Setaria italica	80.14	5.00e-132	463.00
IUUC-Tsy-119548	Tarsius syrichta	31.96	2.00e-08	52.40

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence