iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-045347

Ensembl Protein ID

ENSGGOP00000024812.1

UniProt Accession

G3S9P5; G3S9P5_GORGO

Protein Name

Uncharacterized protein

Gene Name

PHIP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000001706.2	ENSGGOT00000028110.1	ENSGGOP00000024812.1
ENSGGOG00000001706.2	ENSGGOT00000001721.2	ENSGGOP00000001684.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-34	117.2	172	209
UBD/Beta-Prp	4.10e-52	177.6	271	532

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+ f  + +++ +GsdD+ +k+W +++g+ll
   Q: 172  GHLSSVYCVTFdRTgRRIFTGSDDCLVKIWATDDGRLL 209
           8**********955599*****************9987 PP

UBD/Beta-Prp

   S: 19   spdksllatgsrdgtikvwdvttgkl.....lrsl.sgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsv 97
           s +k++l ++++dgti  w ++ g+l      +++ +   ++v+ ++  fs  g +l+tgs+D++i+v+     +++ ++ l+ h+d+v
   Q: 271  SGSKRYLSSTGADGTICFWLWDAGTLkinprPAKFtERPRPGVQMICssFSAGGMFLATGSTDHIIRVYffGSGQPEKISELEFHTDKV 359
           67899***********999999999988988555547777888765522777888**************777779999*********** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
            s++fs +++++vsGs+d t+r+w+ + +++ +                  +++++  v++v+++  +n ++++ ++ t+++W++ tg+
   Q: 360  DSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSIlldmatrpagqnlqgiEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQ 448
           ********************************99***************888899999******************************* PP
   S: 171  llrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           l++ l g h+d v  l+   fd+  + l s+++dg v++wdl +g  +r++ +         v + + sp++++++++ s+g + i+
   Q: 449  LIHVLMG-HEDEVFVLEphpFDP--RVLFSAGHDGNVIVWDLARGVKIRSYFNMIegqghGAVFDCKCSPDGQHFACTDSHGHLLIF 532
           ******9.*********999999..89******************999998875544445566667777999999999999988887 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MSCERKGLSE LRSGGGERAS RGRGPGSRGV LSPQLLPRRT DWTGKEHPRT YQNLVKYYRH 60
LAPDHLLQIC HRLGPLLEQE IPQSVPGVQT LLGAGRQSLL RTNKSCKHVV WKGSALAALH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTTGTG AGAGGAAAGG CCTCTCGGAG CTGCGATCGG GTAAGTCGGG GGGCTGCCGG 60
GGCCGCTGGC ACCGGGCGAT TCCGCCCGCG GTCCCCCGCC CNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR028738--PHIP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0007010--P:cytoskeleton organization
GO:0008286--P:insulin receptor signaling pathway
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0022604--P:regulation of cell morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003700	Anas platyrhynchos	85.48	0.00e+00	2876.00
IUUC-Aca-004474	Anolis carolinensis	81.01	0.00e+00	2782.00
IUUC-Cja-018868	Callithrix jacchus	94.30	0.00e+00	3308.00
IUUC-Cpo-022077	Cavia porcellus	90.93	0.00e+00	3082.00
IUUC-Csa-023618	Chlorocebus sabaeus	96.18	0.00e+00	1706.00
IUUC-Cho-024794	Choloepus hoffmanni	90.75	0.00e+00	875.00
IUUC-Dor-030195	Dipodomys ordii	90.09	0.00e+00	1461.00
IUUC-Ete-032748	Echinops telfairi	83.05	0.00e+00	1152.00
IUUC-Eca-034274	Equus caballus	98.75	0.00e+00	1603.00
IUUC-Eeu-034688	Erinaceus europaeus	83.65	0.00e+00	1406.00
IUUC-Fal-037465	Ficedula albicollis	84.75	0.00e+00	2876.00
IUUC-Gmo-039451	Gadus morhua	68.38	0.00e+00	721.00
IUUC-Gga-040798	Gallus gallus	84.96	0.00e+00	2909.00
IUUC-Hvu-047706	Hordeum vulgare	31.84	1.00e-37	150.00
IUUC-Itr-048843	Ictidomys tridecemlineatus	93.47	0.00e+00	1180.00
IUUC-Lch-050646	Latimeria chalumnae	81.86	0.00e+00	1427.00
IUUC-Loc-052672	Lepisosteus oculatus	70.85	0.00e+00	2377.00
IUUC-Laf-054140	Loxodonta africana	98.13	0.00e+00	1629.00
IUUC-Mdo-061903	Monodelphis domestica	92.71	0.00e+00	1661.00
IUUC-Mmu-063772	Mus musculus	94.79	0.00e+00	1660.00
IUUC-Mpu-066359	Mustela putorius furo	94.20	0.00e+00	1591.00
IUUC-Mlu-067928	Myotis lucifugus	98.31	0.00e+00	1652.00
IUUC-Opr-070971	Ochotona princeps	74.84	0.00e+00	959.00
IUUC-Ont-072221	Oreochromis niloticus	76.34	0.00e+00	1274.00
IUUC-Ocu-074033	Oryctolagus cuniculus	94.51	0.00e+00	2873.00
IUUC-Ogl-077493	Oryza glaberrima	26.93	4.00e-29	124.00
IUUC-Ogu-078641	Oryza glumaepatula	24.28	1.00e-29	125.00
IUUC-Oin-079669	Oryza indica	31.13	3.00e-52	199.00
IUUC-Olo-080755	Oryza longistaminata	31.65	2.00e-54	207.00
IUUC-Oni-082991	Oryza nivara	27.78	1.00e-39	159.00
IUUC-Oga-088578	Otolemur garnettii	98.88	0.00e+00	1608.00
IUUC-Pab-098402	Pongo abelii	96.88	0.00e+00	1683.00
IUUC-Pca-101128	Procavia capensis	92.39	0.00e+00	1471.00
IUUC-Rno-106013	Rattus norvegicus	92.21	0.00e+00	1582.00
IUUC-Sit-110017	Setaria italica	31.34	4.00e-55	210.00
IUUC-Sar-113520	Sorex araneus	90.87	0.00e+00	1535.00
IUUC-Ssc-115461	Sus scrofa	93.44	0.00e+00	1591.00
IUUC-Tgu-116821	Taeniopygia guttata	84.48	0.00e+00	2874.00
IUUC-Tsy-119132	Tarsius syrichta	88.15	0.00e+00	1323.00
IUUC-Tbe-127479	Tupaia belangeri	92.84	0.00e+00	1460.00
IUUC-Vpa-130160	Vicugna pacos	98.76	0.00e+00	1619.00
IUUC-Xtr-132717	Xenopus tropicalis	72.95	0.00e+00	2512.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence