iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FBgn0039705	FBtr0339144	FBpp0308289
FBgn0039705	FBtr0085530	FBpp0084896
FBgn0039705	FBtr0085528	FBpp0084894

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-29	100.9	544	570
UBD/Beta-Prp	1.40e-53	182.0	320	534

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 11   f......sd.tllvsGsdDgtikvWDl 30
           f      s+   +++Gs Dg i++W++
   Q: 544  FarasfnSSgLKIACGSADGAIYIWNV 570
           444444644467*************97 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvls 99
             +++h++  ++v +sp ++++atg++d+++k+wd+ + ++   + lsg +a++++v+f+++g +++ +s+D+ ++vw + ++   htl+gh+ +v++
   Q: 320  MKFEAHENESHAVRWSPVERMVATGGADRKVKLWDIGKNSTepRAVLSGSSAGINSVDFDSTGAYILGTSNDYGARVWTVMDNRLRHTLTGHSGKVMA 417
           5678999999****************************999767778*************************************************** PP
   S: 100  lsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvs 197
            ++ ++  k+v+Gshdrt+++wdl++  c+e t+   ++ +  v++++ g+ ++sG++D+++r+Wd++t+k  ++       +++sl+++++ ++l+ 
   Q: 418  AKYVQEPIKVVTGSHDRTLKIWDLRSIACIE-TKFAGSSCNDLVTTDSLGSTIISGHYDKKIRFWDIRTEKQADDVLM--PAKITSLDLSKDCNYLIC 512
           *******************************.9999999*************************************85..****************** PP
   S: 198  gsldgtvklwdlqtgecvrtln 219
             +d t+kl dl++++++ t++
   Q: 513  SVRDDTIKLLDLRKNQVISTFT 534
           *******************997 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MSTEEHVWRA HVVRRLRERN RKECDNFKEI IEQNNRLIDH VAQLKADNLK ISVENEQLRN 60
AVSTGGTGSN VAIATLEKKL LSQQEELTEL HKRKGENSQM IVDLNQKVEQ QRIIISEKEH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATAACATCG ATGCATCGAT GTGCCGTGAC ATCACTAATA TGAACAGCTG AACAACAATA 60
ATCATATTTG GTTAAAAACA ATTATGCGAA TAAACGCAGC CGCCTTATAG CGCCCGTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0034274--C:Atg12-Atg5-Atg16 complex
GO:0000421--C:autophagosome membrane
GO:0000045--P:autophagosome assembly
GO:0006914--P:autophagy
GO:0009267--P:cellular response to starvation
GO:0061723--P:glycophagy
GO:0035096--P:larval midgut cell programmed cell death
GO:0016236--P:macroautophagy
GO:0010506--P:regulation of autophagy

KEGG

dme:Dmel_CG31033

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002242	Ailuropoda melanoleuca	37.59	6.00e-99	353.00
IUUC-Apl-003384	Anas platyrhynchos	40.00	1.00e-122	432.00
IUUC-Aca-004962	Anolis carolinensis	38.81	8.00e-115	406.00
IUUC-Aly-005435	Arabidopsis lyrata	30.82	2.00e-35	142.00
IUUC-Ath-006948	Arabidopsis thaliana	30.82	8.00e-36	144.00
IUUC-Ame-010915	Astyanax mexicanus	49.67	7.00e-87	313.00
IUUC-Bta-012388	Bos taurus	38.79	6.00e-117	414.00
IUUC-Bdi-014231	Brachypodium distachyon	28.17	1.00e-30	126.00
IUUC-Bol-016174	Brassica oleracea	31.51	1.00e-36	146.00
IUUC-Bra-017165	Brassica rapa	30.82	2.00e-36	146.00
IUUC-Cel-018234	Caenorhabditis elegans	27.88	3.00e-57	215.00
IUUC-Cja-018898	Callithrix jacchus	35.33	2.00e-90	325.00
IUUC-Cfa-020484	Canis familiaris	38.64	1.00e-115	409.00
IUUC-Cpo-022156	Cavia porcellus	38.11	4.00e-116	410.00
IUUC-Csa-024019	Chlorocebus sabaeus	37.95	1.00e-114	405.00
IUUC-Cho-024311	Choloepus hoffmanni	45.28	6.00e-61	228.00
IUUC-Cin-025260	Ciona intestinalis	31.67	9.00e-85	306.00
IUUC-Csv-025836	Ciona savignyi	40.10	2.00e-45	174.00
IUUC-Dre-027702	Danio rerio	50.84	4.00e-92	331.00
IUUC-Dno-029728	Dasypus novemcinctus	37.92	5.00e-115	407.00
IUUC-Dor-030897	Dipodomys ordii	28.04	2.00e-59	222.00
IUUC-Ete-032969	Echinops telfairi	51.20	7.00e-88	317.00
IUUC-Eca-034214	Equus caballus	41.19	8.00e-107	379.00
IUUC-Eeu-034537	Erinaceus europaeus	37.43	8.00e-96	343.00
IUUC-Fca-036005	Felis catus	40.07	3.00e-112	398.00
IUUC-Fal-037593	Ficedula albicollis	41.20	5.00e-119	420.00
IUUC-Gmo-039042	Gadus morhua	42.27	1.00e-65	243.00
IUUC-Gga-040986	Gallus gallus	38.82	9.00e-123	433.00
IUUC-Gac-041351	Gasterosteus aculeatus	37.94	3.00e-118	418.00
IUUC-Gma-043265	Glycine max	32.67	5.00e-40	158.00
IUUC-Ggo-045427	Gorilla gorilla	36.97	1.00e-112	399.00
IUUC-Hsa-046632	Homo sapiens	37.99	3.00e-113	401.00
IUUC-Itr-048504	Ictidomys tridecemlineatus	38.27	3.00e-116	411.00
IUUC-Lch-050669	Latimeria chalumnae	38.24	1.00e-52	199.00
IUUC-Lpe-051254	Leersia perrieri	28.57	3.00e-32	132.00
IUUC-Loc-052610	Lepisosteus oculatus	39.62	4.00e-121	427.00
IUUC-Laf-053936	Loxodonta africana	38.81	4.00e-116	410.00
IUUC-Mcc-055504	Macaca mulatta	49.83	6.00e-88	317.00
IUUC-Meu-056516	Macropus eugenii	50.17	7.00e-89	320.00
IUUC-Mtr-058062	Medicago truncatula	30.54	4.00e-38	151.00
IUUC-Mga-059777	Meleagris gallopavo	39.04	2.00e-119	421.00
IUUC-Mmr-061298	Microcebus murinus	38.50	4.00e-116	411.00
IUUC-Mdo-062969	Monodelphis domestica	37.96	4.00e-114	404.00
IUUC-Mmu-064076	Mus musculus	38.18	4.00e-113	401.00
IUUC-Mac-065161	Musa acuminata	29.41	2.00e-34	139.00
IUUC-Mpu-066196	Mustela putorius furo	37.86	2.00e-113	402.00
IUUC-Mlu-067651	Myotis lucifugus	38.20	4.00e-115	407.00
IUUC-Nle-069853	Nomascus leucogenys	37.34	8.00e-110	390.00
IUUC-Opr-071039	Ochotona princeps	37.77	1.00e-55	210.00
IUUC-Ont-072489	Oreochromis niloticus	38.49	3.00e-122	431.00
IUUC-Oan-072703	Ornithorhynchus anatinus	37.54	1.00e-108	386.00
IUUC-Ocu-074205	Oryctolagus cuniculus	37.10	1.00e-110	392.00
IUUC-Oba-075619	Oryza barthii	28.21	1.00e-29	123.00
IUUC-Obr-076632	Oryza brachyantha	28.05	7.00e-32	131.00
IUUC-Ogl-077671	Oryza glaberrima	28.21	1.00e-29	123.00
IUUC-Ogu-078052	Oryza glumaepatula	28.21	1.00e-29	123.00
IUUC-Oin-079611	Oryza indica	28.57	4.00e-28	118.00
IUUC-Olo-080408	Oryza longistaminata	28.21	2.00e-29	122.00
IUUC-Ome-081560	Oryza meridionalis	27.86	2.00e-29	122.00
IUUC-Oni-082145	Oryza nivara	28.21	1.00e-29	123.00
IUUC-Opu-083918	Oryza punctata	27.86	6.00e-29	121.00
IUUC-Oru-084858	Oryza rufipogon	28.57	3.00e-28	119.00
IUUC-Osa-086277	Oryza sativa	28.57	4.00e-28	118.00
IUUC-Ola-086964	Oryzias latipes	42.18	1.00e-59	222.00
IUUC-Olu-087622	Ostreococcus lucimarinus	30.54	8.00e-36	143.00
IUUC-Oga-088765	Otolemur garnettii	49.83	1.00e-88	320.00
IUUC-Oar-090196	Ovis aries	41.17	6.00e-108	384.00
IUUC-Ptr-091676	Pan troglodytes	38.15	1.00e-113	403.00
IUUC-Pan-092068	Papio anubis	37.44	2.00e-114	405.00
IUUC-Psi-093367	Pelodiscus sinensis	39.58	2.00e-117	415.00
IUUC-Ppa-095699	Physcomitrella patens	27.98	3.00e-31	129.00
IUUC-Pfo-096067	Poecilia formosa	50.17	2.00e-91	328.00
IUUC-Pab-098111	Pongo abelii	36.97	2.00e-112	398.00
IUUC-Pop-099116	Populus trichocarpa	32.19	1.00e-36	147.00
IUUC-Pca-100680	Procavia capensis	52.51	3.00e-67	248.00
IUUC-Ppe-101790	Prunus persica	31.62	2.00e-38	152.00
IUUC-Pva-102871	Pteropus vampyrus	38.94	2.00e-113	402.00
IUUC-Rno-106088	Rattus norvegicus	38.18	2.00e-114	405.00
IUUC-Sha-106984	Sarcophilus harrisii	40.21	2.00e-115	408.00
IUUC-Smo-108983	Selaginella moellendorffii	30.74	6.00e-40	157.00
IUUC-Sit-110828	Setaria italica	29.08	2.00e-33	135.00
IUUC-Sly-111009	Solanum lycopersicum	31.05	1.00e-39	156.00
IUUC-Stu-112370	Solanum tuberosum	30.72	2.00e-39	155.00
IUUC-Sar-113109	Sorex araneus	38.14	3.00e-34	138.00
IUUC-Sbi-114819	Sorghum bicolor	28.67	5.00e-33	134.00
IUUC-Ssc-116241	Sus scrofa	37.62	7.00e-107	380.00
IUUC-Tgu-116576	Taeniopygia guttata	39.58	2.00e-122	432.00
IUUC-Tru-118336	Takifugu rubripes	42.14	3.00e-68	251.00
IUUC-Tsy-119006	Tarsius syrichta	50.51	9.00e-88	317.00
IUUC-Tni-120300	Tetraodon nigroviridis	39.15	2.00e-117	415.00
IUUC-Tca-121002	Theobroma cacao	34.15	1.00e-39	156.00
IUUC-Tae-124868	Triticum aestivum	29.05	1.00e-28	120.00
IUUC-Tur-126463	Triticum urartu	28.38	3.00e-27	116.00
IUUC-Tbe-127631	Tupaia belangeri	40.78	3.00e-102	364.00
IUUC-Ttr-129005	Tursiops truncatus	51.38	1.00e-74	273.00
IUUC-Vpa-130246	Vicugna pacos	46.12	6.00e-54	204.00
IUUC-Vvi-130878	Vitis vinifera	31.19	6.00e-36	144.00
IUUC-Xtr-132798	Xenopus tropicalis	36.77	8.00e-103	367.00
IUUC-Xma-133264	Xiphophorus maculatus	39.00	8.00e-116	410.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence