iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-006928

UUCD1 version

UUC-ArT-01185

Ensembl Protein ID

AT3G63530.2

UniProt Accession

Q8L649; C0Z296; BB_ARATH

Genbank Protein ID

CAD32249.1; AEE80499.1; AEE80500.1; AAQ22666.1; BAH56825.1; BAE99660.1

Protein Name

E3 ubiquitin ligase BIG BROTHER; Protein ENHANCER OF DA1-1; RING-type E3 ubiquitin transferase BIG BROTHER

Genbank Nucleotide ID

AL732522; CP002686; CP002686; BT010197; AK318710; AK227673

Gene Name

BB; EOD1; At3g63530; TEL3S.1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT3G63530	AT3G63530.2	AT3G63530.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	16461280

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	8.80e-07	30.2	197	238

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf...kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC+  +   ++  + lpC+Hv+h +C+ kw       s +  CP+C+
   Q: 197  CVICQLKYkigER-QMNLPCKHVYHSECISKW------LSINKVCPVCN 238
           9***887777655.445***************......**********7 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

E3 ubiquitin-ligase that limits organ size, and possibly seed size, in a dose-dependent manner. Negatively regulates the duration of cell proliferation in leaves and petals independently of the major phytohormones (e.g. auxin, cytokinin, gibberellin, brassinosteroids, ethylene, abscisic acid, jasmonic acid), probably by targeting growth stimulators for degradation.

Protein Sequence
(Fasta)

MNGDNRPVED AHYTETGFPY AATGSYMDFY GGAAQGPLNY DHAATMHPQD NLYWTMNTNA 60
YKFGFSGSDN ASFYGSYDMN DHLSRMSIGR TNWDYHPMVN VADDPENTVA RSVQIGDTDE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCAAGGCCG AAAGCTGTAC TTTTGATTTA AATATGTGAT CCATCAATGA AGAACAAATA 60
CTCTCTCATT CCTTTTTTTT AATTTAAAGG AAGAAAGAGA AAAATTAAAG AAGCAAATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR033276--BB
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0048437--P:floral organ development
GO:0046621--P:negative regulation of organ growth
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0016567--P:protein ubiquitination

KEGG

ath:AT3G63530

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000725	Aegilops tauschii	50.40	4.00e-56	210.00
IUUC-Atr-002639	Amborella trichopoda	47.35	3.00e-55	207.00
IUUC-Aly-006328	Arabidopsis lyrata	94.35	1.00e-142	498.00
IUUC-Bdi-014877	Brachypodium distachyon	50.00	4.00e-55	207.00
IUUC-Bol-015817	Brassica oleracea	83.33	3.00e-119	420.00
IUUC-Bra-017680	Brassica rapa	85.94	2.00e-127	447.00
IUUC-Gma-044301	Glycine max	54.81	6.00e-73	266.00
IUUC-Hvu-047311	Hordeum vulgare	49.19	4.00e-53	200.00
IUUC-Lpe-051357	Leersia perrieri	46.37	7.00e-56	209.00
IUUC-Mtr-058385	Medicago truncatula	52.28	1.00e-72	265.00
IUUC-Mac-064965	Musa acuminata	46.56	6.00e-51	192.00
IUUC-Oba-075640	Oryza barthii	50.81	6.00e-56	210.00
IUUC-Obr-076687	Oryza brachyantha	51.21	2.00e-56	211.00
IUUC-Ogl-077270	Oryza glaberrima	50.81	3.00e-56	211.00
IUUC-Ogu-078788	Oryza glumaepatula	51.61	6.00e-56	210.00
IUUC-Oin-079201	Oryza indica	50.81	3.00e-56	211.00
IUUC-Olo-080862	Oryza longistaminata	49.59	3.00e-52	197.00
IUUC-Ome-081787	Oryza meridionalis	50.00	7.00e-55	207.00
IUUC-Oni-082723	Oryza nivara	50.81	3.00e-56	211.00
IUUC-Opu-084164	Oryza punctata	51.82	4.00e-57	213.00
IUUC-Oru-084238	Oryza rufipogon	50.81	3.00e-56	210.00
IUUC-Osa-085989	Oryza sativa	50.81	3.00e-56	211.00
IUUC-Olu-087709	Ostreococcus lucimarinus	43.75	2.00e-18	82.80
IUUC-Pop-099571	Populus trichocarpa	58.94	3.00e-83	300.00
IUUC-Ppe-101485	Prunus persica	58.23	1.00e-73	268.00
IUUC-Sit-110753	Setaria italica	50.42	6.00e-63	233.00
IUUC-Sly-111661	Solanum lycopersicum	44.94	2.00e-58	218.00
IUUC-Stu-111957	Solanum tuberosum	46.12	6.00e-61	226.00
IUUC-Sbi-114143	Sorghum bicolor	49.79	6.00e-62	229.00
IUUC-Tca-121815	Theobroma cacao	57.26	2.00e-81	294.00
IUUC-Tae-123276	Triticum aestivum	50.40	3.00e-56	211.00
IUUC-Tur-125974	Triticum urartu	50.40	2.00e-55	208.00
IUUC-Vvi-130977	Vitis vinifera	54.18	2.00e-76	277.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence