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Tag Content
iUUCD ID IUUC-Uma-129551
Ensembl Protein ID KIS66478
UniProt Accession Q4P341; A0A0D1CHP3; NACA_USTMA
Genbank Protein ID KIS66478.1
Protein Name Nascent polypeptide-associated complex subunit alpha; Alpha-NAC
Genbank Nucleotide ID CM003157
Gene Name EGD2; UMAG_05472
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
UMAG_05472 KIS66478 KIS66478
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/UBA 38.57 3.00e-11 62.80 IUUC-Sce-106371
UBD/Alpha-Helix/UBA 44.97 1.00e-22 100.00 IUUC-Spo-108121
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Ustilago maydis
Functional Description
(View)

Functional Description



     Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Protein Sequence
(Fasta)
MSATVEEIAD DVQDLNVQEF DSDDAGADVH ASDKVASRAE RKSRKALQGI GLKKVGGITR 60
VTMRRPRGHL YVIAQPEVYK SSHSDVYIVF GEAKAEDMSQ LAQAQAAQQM AQAEAQERLL 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Uma-129551|UBD,UBA|Ustilago maydis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTCTGCTA CCGTTGAAGA AATCGCCGAC GACGTTCAGG ACGTAAGTCT GACTCTCTTC 60
AGCTGCGATG ACCTACCGGT TGGACCGCAA GAAGTTGGAA TCTTGATGCG CAGAAACTGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Uma-129551|UBD,UBA|Ustilago maydis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR016641--EGD2/NACA
IPR002715--Nas_poly-pep-assoc_cplx_dom

PROSITE

PS51151--NAC_AB

Pfam

PF01849--NAC

SMART

SM01407--NAC

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0015031--P:protein transport

KEGG uma:UMAG_05472
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001167 Aegilops tauschii 42.96 1.00e-20 90.90
IUUC-Aml-001719 Ailuropoda melanoleuca 46.36 7.00e-24 105.00
IUUC-Atr-002586 Amborella trichopoda 36.02 4.00e-15 72.80
IUUC-Apl-003190 Anas platyrhynchos 40.52 5.00e-23 98.20
IUUC-Aca-005265 Anolis carolinensis 43.71 1.00e-25 107.00
IUUC-Aly-006488 Arabidopsis lyrata 47.18 6.00e-22 95.50
IUUC-Ath-006809 Arabidopsis thaliana 49.28 3.00e-21 92.80
IUUC-Ago-007936 Ashbya gossypii 36.94 7.00e-21 91.70
IUUC-Acl-008036 Aspergillus clavatus 56.06 2.00e-18 84.00
IUUC-Afl-008462 Aspergillus flavus 49.38 7.00e-20 88.60
IUUC-Afu-008832 Aspergillus fumigatus 58.06 2.00e-18 84.00
IUUC-Ani-009246 Aspergillus nidulans 55.07 1.00e-19 87.40
IUUC-Ang-009808 Aspergillus niger 56.06 2.00e-18 83.60
IUUC-Aor-009972 Aspergillus oryzae 49.38 7.00e-20 88.60
IUUC-Ame-011674 Astyanax mexicanus 46.36 7.00e-26 108.00
IUUC-Bgr-012162 Blumeria graminis 63.49 2.00e-20 90.90
IUUC-Bta-012508 Bos taurus 45.03 5.00e-25 105.00
IUUC-Bci-013643 Botrytis cinerea 58.33 7.00e-21 92.00
IUUC-Bdi-014854 Brachypodium distachyon 41.38 1.00e-18 84.30
IUUC-Bol-015132 Brassica oleracea 47.89 5.00e-23 99.00
IUUC-Bra-017540 Brassica rapa 44.37 8.00e-19 85.10
IUUC-Cel-018111 Caenorhabditis elegans 41.29 3.00e-24 102.00
IUUC-Cja-019846 Callithrix jacchus 39.22 2.00e-23 103.00
IUUC-Cfa-020429 Canis familiaris 46.36 5.00e-25 105.00
IUUC-Cpo-022542 Cavia porcellus 46.36 6.00e-25 105.00
IUUC-Cre-022679 Chlamydomonas reinhardtii 40.13 4.00e-26 108.00
IUUC-Csa-023260 Chlorocebus sabaeus 42.38 2.00e-23 103.00
IUUC-Cho-024869 Choloepus hoffmanni 60.61 1.00e-06 44.70
IUUC-Cin-025166 Ciona intestinalis 45.73 2.00e-27 114.00
IUUC-Csv-026284 Ciona savignyi 46.15 9.00e-21 90.50
IUUC-Cgl-026520 Colletotrichum gloeosporioides 50.65 6.00e-26 108.00
IUUC-Cne-026920 Cryptococcus neoformans 38.95 3.00e-21 92.80
IUUC-Cme-027301 Cyanidioschyzon merolae 38.41 1.00e-18 84.70
IUUC-Dre-028709 Danio rerio 47.02 1.00e-25 110.00
IUUC-Dno-029786 Dasypus novemcinctus 46.36 4.00e-24 105.00
IUUC-Dor-030962 Dipodomys ordii 46.36 5.00e-25 105.00
IUUC-Dme-032061 Drosophila melanogaster 45.70 1.00e-19 87.40
IUUC-Ete-032965 Echinops telfairi 41.72 4.00e-24 102.00
IUUC-Eca-034049 Equus caballus 44.37 3.00e-24 102.00
IUUC-Eeu-034673 Erinaceus europaeus 46.36 5.00e-25 105.00
IUUC-Fca-036369 Felis catus 46.36 5.00e-24 105.00
IUUC-Fal-037006 Ficedula albicollis 46.36 4.00e-25 105.00
IUUC-Fox-037704 Fusarium oxysporum 56.92 1.00e-19 87.80
IUUC-Fso-038247 Fusarium solani 45.96 3.00e-23 99.80
IUUC-Gmo-039002 Gadus morhua 41.56 1.00e-24 104.00
IUUC-Ggr-039888 Gaeumannomyces graminis 58.46 7.00e-19 85.10
IUUC-Gga-040237 Gallus gallus 46.36 6.00e-25 105.00
IUUC-Gac-041800 Gasterosteus aculeatus 45.70 2.00e-25 108.00
IUUC-Gma-043275 Glycine max 43.71 2.00e-27 113.00
IUUC-Ggo-045163 Gorilla gorilla 40.40 1.00e-25 107.00
IUUC-Hsa-045795 Homo sapiens 46.36 2.00e-24 107.00
IUUC-Hvu-047376 Hordeum vulgare 42.96 1.00e-20 91.30
IUUC-Itr-048152 Ictidomys tridecemlineatus 46.36 5.00e-25 105.00
IUUC-Kpa-049166 Komagataella pastoris 42.42 1.00e-11 61.60
IUUC-Lch-050076 Latimeria chalumnae 45.70 8.00e-26 108.00
IUUC-Lpe-051258 Leersia perrieri 45.07 2.00e-21 94.00
IUUC-Loc-052292 Lepisosteus oculatus 47.02 3.00e-25 107.00
IUUC-Lma-053293 Leptosphaeria maculans 48.57 9.00e-22 94.70
IUUC-Laf-054393 Loxodonta africana 37.50 3.00e-23 99.80
IUUC-Mcc-054632 Macaca mulatta 46.36 5.00e-24 105.00
IUUC-Meu-056242 Macropus eugenii 58.73 2.00e-19 87.00
IUUC-Mor-057099 Magnaporthe oryzae 58.46 4.00e-19 85.90
IUUC-Mpo-057543 Magnaporthe poae 54.24 7.00e-14 68.20
IUUC-Mtr-058112 Medicago truncatula 40.70 5.00e-27 112.00
IUUC-Mla-059166 Melampsora laricipopulina 42.86 8.00e-30 121.00
IUUC-Mga-059406 Meleagris gallopavo 46.36 8.00e-25 105.00
IUUC-Mvi-060390 Microbotryum violaceum 38.73 5.00e-23 98.60
IUUC-Mmr-061569 Microcebus murinus 46.36 4.00e-25 105.00
IUUC-Mdo-062077 Monodelphis domestica 46.36 2.00e-23 102.00
IUUC-Mmu-063984 Mus musculus 46.36 4.00e-23 103.00
IUUC-Mac-065175 Musa acuminata 40.69 1.00e-21 94.40
IUUC-Mpu-066751 Mustela putorius furo 42.76 2.00e-23 103.00
IUUC-Mlu-068234 Myotis lucifugus 46.36 5.00e-25 105.00
IUUC-Nfi-068541 Neosartorya fischeri 58.06 2.00e-18 84.00
IUUC-Ncr-068830 Neurospora crassa 58.46 3.00e-20 89.70
IUUC-Nle-069126 Nomascus leucogenys 45.03 8.00e-25 105.00
IUUC-Opr-070742 Ochotona princeps 46.36 5.00e-25 105.00
IUUC-Ont-071828 Oreochromis niloticus 45.70 6.00e-26 108.00
IUUC-Oan-073462 Ornithorhynchus anatinus 60.61 3.00e-06 46.60
IUUC-Ocu-074890 Oryctolagus cuniculus 40.40 1.00e-23 104.00
IUUC-Oba-075995 Oryza barthii 44.37 2.00e-23 100.00
IUUC-Obr-076668 Oryza brachyantha 41.55 1.00e-23 100.00
IUUC-Ogl-077307 Oryza glaberrima 43.66 3.00e-24 103.00
IUUC-Ogu-078289 Oryza glumaepatula 43.66 3.00e-24 103.00
IUUC-Oin-079287 Oryza indica 44.37 2.00e-23 100.00
IUUC-Olo-080686 Oryza longistaminata 40.37 3.00e-20 89.70
IUUC-Ome-081567 Oryza meridionalis 43.66 2.00e-24 103.00
IUUC-Oni-082873 Oryza nivara 44.37 2.00e-23 100.00
IUUC-Opu-083291 Oryza punctata 43.66 3.00e-24 103.00
IUUC-Oru-085045 Oryza rufipogon 43.66 2.00e-24 103.00
IUUC-Osa-086265 Oryza sativa 43.66 3.00e-24 103.00
IUUC-Ola-087531 Oryzias latipes 45.70 2.00e-26 110.00
IUUC-Olu-087895 Ostreococcus lucimarinus 34.72 3.00e-18 82.00
IUUC-Oga-088239 Otolemur garnettii 46.36 5.00e-25 105.00
IUUC-Oar-089723 Ovis aries 46.36 5.00e-24 105.00
IUUC-Ptr-090481 Pan troglodytes 41.72 8.00e-22 98.20
IUUC-Pan-092223 Papio anubis 46.36 6.00e-24 104.00
IUUC-Psi-093588 Pelodiscus sinensis 46.36 5.00e-25 105.00
IUUC-Pma-094702 Petromyzon marinus 45.70 2.00e-25 107.00
IUUC-Pno-094927 Phaeosphaeria nodorum 45.71 6.00e-21 92.00
IUUC-Ppa-095389 Physcomitrella patens 41.56 4.00e-23 99.00
IUUC-Pfo-096744 Poecilia formosa 46.36 1.00e-25 107.00
IUUC-Pab-098044 Pongo abelii 46.36 5.00e-25 105.00
IUUC-Pop-099384 Populus trichocarpa 45.03 1.00e-26 110.00
IUUC-Pca-100355 Procavia capensis 41.72 5.00e-23 102.00
IUUC-Ppe-101786 Prunus persica 40.85 1.00e-21 94.70
IUUC-Pva-102494 Pteropus vampyrus 45.03 3.00e-25 106.00
IUUC-Pgr-103303 Puccinia graminis 43.07 2.00e-32 130.00
IUUC-Ptt-103748 Puccinia triticina 41.41 7.00e-20 88.60
IUUC-Pte-104368 Pyrenophora teres 43.50 2.00e-29 120.00
IUUC-Pyt-104542 Pyrenophora triticirepentis 44.00 1.00e-29 121.00
IUUC-Rno-105387 Rattus norvegicus 46.36 5.00e-23 102.00
IUUC-Sce-106371 Saccharomyces cerevisiae 35.12 1.00e-17 80.50
IUUC-Sha-107189 Sarcophilus harrisii 46.36 5.00e-25 105.00
IUUC-Sja-107942 Schizosaccharomyces japonicus 45.83 1.00e-12 64.30
IUUC-Spo-108121 Schizosaccharomyces pombe 46.58 6.00e-23 98.20
IUUC-Ssl-108595 Sclerotinia sclerotiorum 57.33 1.00e-20 91.30
IUUC-Smo-108783 Selaginella moellendorffii 39.31 2.00e-21 94.00
IUUC-Sit-110180 Setaria italica 41.55 7.00e-23 98.60
IUUC-Sly-110957 Solanum lycopersicum 41.55 3.00e-21 93.20
IUUC-Stu-112873 Solanum tuberosum 41.55 2.00e-20 90.50
IUUC-Sar-113668 Sorex araneus 60.61 9.00e-07 45.10
IUUC-Sbi-114223 Sorghum bicolor 42.76 2.00e-23 100.00
IUUC-Sre-115220 Sporisorium reilianum 95.88 2.00e-51 193.00
IUUC-Ssc-116119 Sus scrofa 46.36 5.00e-25 105.00
IUUC-Tgu-116528 Taeniopygia guttata 46.36 4.00e-25 105.00
IUUC-Tru-117538 Takifugu rubripes 46.36 5.00e-26 108.00
IUUC-Tsy-118855 Tarsius syrichta 60.61 1.00e-06 44.70
IUUC-Tni-120134 Tetraodon nigroviridis 45.70 1.00e-26 110.00
IUUC-Tca-121524 Theobroma cacao 40.69 8.00e-22 95.10
IUUC-Tre-121915 Trichoderma reesei 62.12 2.00e-18 84.00
IUUC-Tvi-122411 Trichoderma virens 63.93 5.00e-17 79.00
IUUC-Tae-124851 Triticum aestivum 42.96 1.00e-20 91.30
IUUC-Tur-126821 Triticum urartu 42.96 9.00e-21 91.30
IUUC-Tme-126875 Tuber melanosporum 58.46 1.00e-19 87.40
IUUC-Tbe-127759 Tupaia belangeri 40.58 2.00e-17 80.10
IUUC-Ttr-129124 Tursiops truncatus 44.37 3.00e-24 106.00
IUUC-Vda-129992 Verticillium dahliae 53.85 2.00e-28 116.00
IUUC-Vpa-130096 Vicugna pacos 45.70 8.00e-23 98.20
IUUC-Vvi-130940 Vitis vinifera 42.96 2.00e-19 87.00
IUUC-Xtr-132454 Xenopus tropicalis 46.36 8.00e-25 105.00
IUUC-Xma-133842 Xiphophorus maculatus 46.36 9.00e-26 108.00
IUUC-Yli-134485 Yarrowia lipolytica 41.46 7.00e-16 75.10
IUUC-Zma-135748 Zea mays 44.83 2.00e-25 107.00
Created Date 25-Jun-2017

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