iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-007422

UUCD1 version

UUC-ArT-00853

Ensembl Protein ID

AT5G61550.2

UniProt Accession

Q9FKG6; PUB52_ARATH

Genbank Protein ID

BAB08999.1; AED97486.1; ANM70540.1; ANM70541.1; AT5G61550.1

Protein Name

U-box domain-containing protein 52; Plant U-box protein 52; E3 ubiquitin ligase; RING-type E3 ubiquitin transferase; Serine/threonine-protein kinase

Genbank Nucleotide ID

AB012239; CP002688; CP002688; CP002688; AK228422

Gene Name

PUB52; At5g61550; K11J9.12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT5G61550	AT5G61550.2	AT5G61550.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	3.40e-20	72.8	775	844

Active Site

Position(s)	Description	Evidence
612	Proton acceptor	ECO:0000255\|PROSITE-ProRule:PRU00159, ECO:0000255\|PROSITE-ProRule:PRU10027}

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceen 72
           +p++f+Cp+ + +M++P+v+++G+tydr++Ie+wl+++ + +Pvt+ pl +++l+ n+tl + i +w + +
   Q: 775  PPSHFICPLLKGVMNEPCVAADGYTYDREAIEEWLRQKDT-SPVTNLPLPNKNLIANYTLYSAIMEWKSNK 844
           599*******************************999887.**************************9876 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Functions as an E3 ubiquitin ligase.

Protein Sequence
(Fasta)

MEEKKVVRAL SEHLSLPPPP SPSVAVAING KKKSKYVVFW ALEKFIPEGF TDFKLLYVRP 60
PVSYIPTPMG IAVAVSELRE DVVSAYKQEL DWSANEMLRP YKKMFERRKV QVEVLLLDSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCAAACCAA ACCAAACTTA GGGTTCTTCT TTGTTCTCTG CTTCAACAGA ACTACAGGGT 60
AAGCTCTGTT ATGTCTGAAG CTCCATTAGT CTGTTATATT TACATCTAAA TTCTTCTCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR014729--Rossmann-like_a/b/a_fold
IPR008271--Ser/Thr_kinase_AS
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS51698--U_BOX

Pfam

PF00069--Pkinase
PF04564--U-box

SMART

SM00220--S_TKc
SM00504--Ubox

Gene Ontology

GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

ath:AT5G61550

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006136	Arabidopsis lyrata	94.33	0.00e+00	1504.00
IUUC-Bdi-014960	Brachypodium distachyon	50.51	2.00e-143	502.00
IUUC-Bol-015784	Brassica oleracea	84.70	0.00e+00	1387.00
IUUC-Bra-017651	Brassica rapa	84.80	0.00e+00	1378.00
IUUC-Hvu-047815	Hordeum vulgare	49.70	3.00e-134	471.00
IUUC-Smo-109331	Selaginella moellendorffii	50.25	4.00e-113	400.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence