iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117542

UUCD1 version

UUC-TaR-01158

Ensembl Protein ID

ENSTRUP00000045214.1

UniProt Accession

H2V7M5; H2V7M5_TAKRU

Protein Name

Uncharacterized protein

Gene Name

usp10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000017640.1	ENSTRUT00000045366.1	ENSTRUP00000045214.1
ENSTRUG00000017640.1	ENSTRUT00000045367.1	ENSTRUP00000045215.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.50e-67	227.1	459	839

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw......kskkk...............avs 69
           Gl N gN CY+N++LQ+L+++p++ +l+++     l+e++++ +++++++++ +l++e+       k k +                ++
   Q: 459  GLVNKGNWCYINATLQALIACPPMYHLMKS--IPMLSETQRPCTSTPMMDNFVRLVNEFNnmpvpsKAK-QqavgdkvmkdirpgvPFE 544
           9*****************************..4455666678999**************7667664333.2478999999999999*** PP
   S: 70   prellkalkkeaeefs.gyeqqDaqEflaflldqleeelkk..................eknkpkeeeeeedkselsde.......... 129
           p+ ++k l  +++++s + +q+Da+E+l f l++l+ee+                    e+++ +ee           +          
   Q: 545  PTYIYKLLTLIKSSLSeKGRQEDAEEYLGFTLNGLHEEMLAlkklispqeekaptpngpESQSGVEE-----------Daadkdeegse 622
           ***********99966599********************4444466666556655555533333333...........13444444555 PP
   S: 130  .........aeekkkkknk...........slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkee 198
                    +        k           ++i+d+F+g+++ +++ ++  ++s + +pf++l+l++++++ +   ++q++Le ++++e
   Q: 623  deweqvgprN--------KtsitrqadfvrTPITDIFGGHIR-SVVYQQNSKESATLQPFFTLQLDIQSEKIR---TVQEALETMVARE 699
           5455555542........444444555777***********9.688999999*******************99...************* PP
   S: 199  elegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke...kkkYeLiavv 284
           +++g    y++k k++ e +++++l++lP+vL+lhLkRf f+++++++ k++k++++p  L++s+ + s+   +k+   +++Y+L+avv
   Q: 700  SVQG----YTSKTKQEIEISRRVTLEELPPVLVLHLKRFVFEKTGGCQ-KLSKNIDYPVDLEISKDLLSSGVRSKVvkgQRTYRLFAVV 783
           ***8....999******************************9998886.***************955553333333455********** PP
   S: 285  vHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetg.staYvlfYkr 337
           +H+G s+ +GHY+++v +   + Wl++dD+ V+++++   l++++ +taY+l+Y+r
   Q: 784  YHHGnSATGGHYTTDVFHIGLNgWLRIDDQAVKVINQYHLLKQSAeRTAYLLYYRR 839
           ******************87777**************999998778********98 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

KRDLCPQYFF GEFSADEINQ FFVTPRGYVE LPPFNDKVPC VTQSSGNFPW SPNVYVSNSF 60
NVIAAEDYQR IEFGVDEVMD SESVGGKDQL YKVSSTLNPQ APEFILGCQP VQKALQASAP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAACGTGATT TGTGTCCACA GTACTTCTTC GGGGAGTTCA GCGCTGATGA GATCAATCAG 60
TTCTTTGTGA CTCCGCGGGG TTACGTGGAG GTAAGGCAGA AGATGCTCCT TCTCTTGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005769--C:early endosome
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0016579--P:protein deubiquitination
GO:0010506--P:regulation of autophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000082	Aegilops tauschii	31.00	4.00e-48	186.00
IUUC-Aml-001584	Ailuropoda melanoleuca	57.67	0.00e+00	823.00
IUUC-Atr-002927	Amborella trichopoda	35.20	3.00e-59	223.00
IUUC-Apl-003988	Anas platyrhynchos	60.21	0.00e+00	865.00
IUUC-Aca-004461	Anolis carolinensis	83.28	9.00e-152	529.00
IUUC-Aly-006038	Arabidopsis lyrata	33.67	3.00e-55	209.00
IUUC-Ath-007328	Arabidopsis thaliana	33.16	1.00e-53	204.00
IUUC-Ago-007717	Ashbya gossypii	28.84	2.00e-46	181.00
IUUC-Acl-008188	Aspergillus clavatus	34.58	1.00e-60	228.00
IUUC-Afl-008456	Aspergillus flavus	37.76	2.00e-47	182.00
IUUC-Afu-009067	Aspergillus fumigatus	34.99	1.00e-62	234.00
IUUC-Ani-009483	Aspergillus nidulans	32.78	3.00e-60	226.00
IUUC-Ang-009639	Aspergillus niger	33.51	1.00e-58	221.00
IUUC-Aor-010040	Aspergillus oryzae	34.69	3.00e-60	227.00
IUUC-Ate-010310	Aspergillus terreus	32.71	3.00e-60	226.00
IUUC-Ame-011012	Astyanax mexicanus	64.95	0.00e+00	893.00
IUUC-Bgr-012311	Blumeria graminis	35.41	8.00e-50	192.00
IUUC-Bta-013299	Bos taurus	56.98	0.00e+00	780.00
IUUC-Bci-013783	Botrytis cinerea	33.49	1.00e-58	221.00
IUUC-Bdi-015039	Brachypodium distachyon	32.27	1.00e-51	197.00
IUUC-Bol-015806	Brassica oleracea	33.76	7.00e-62	231.00
IUUC-Bra-017076	Brassica rapa	34.27	6.00e-63	235.00
IUUC-Cja-018715	Callithrix jacchus	56.88	0.00e+00	824.00
IUUC-Cfa-020194	Canis familiaris	57.78	0.00e+00	832.00
IUUC-Cpo-022272	Cavia porcellus	73.82	0.00e+00	680.00
IUUC-Cre-022713	Chlamydomonas reinhardtii	34.01	1.00e-34	141.00
IUUC-Csa-023310	Chlorocebus sabaeus	57.60	0.00e+00	836.00
IUUC-Cho-024966	Choloepus hoffmanni	49.42	2.00e-132	466.00
IUUC-Cin-025616	Ciona intestinalis	46.17	9.00e-108	384.00
IUUC-Csv-026043	Ciona savignyi	45.61	2.00e-101	362.00
IUUC-Cgl-026421	Colletotrichum gloeosporioides	31.93	2.00e-46	181.00
IUUC-Cne-026962	Cryptococcus neoformans	34.45	3.00e-50	193.00
IUUC-Cme-027113	Cyanidioschyzon merolae	30.50	3.00e-38	153.00
IUUC-Dre-028072	Danio rerio	67.63	0.00e+00	1063.00
IUUC-Dno-029489	Dasypus novemcinctus	58.20	0.00e+00	849.00
IUUC-Dor-031068	Dipodomys ordii	77.18	8.00e-62	231.00
IUUC-Dse-031553	Dothistroma septosporum	35.93	8.00e-57	215.00
IUUC-Dme-031759	Drosophila melanogaster	44.50	2.00e-90	327.00
IUUC-Ete-032549	Echinops telfairi	51.50	2.00e-149	523.00
IUUC-Eca-033380	Equus caballus	57.86	0.00e+00	838.00
IUUC-Eeu-034818	Erinaceus europaeus	55.56	0.00e+00	785.00
IUUC-Fca-035535	Felis catus	55.97	0.00e+00	738.00
IUUC-Fal-036627	Ficedula albicollis	59.34	0.00e+00	857.00
IUUC-Fox-037904	Fusarium oxysporum	36.69	2.00e-55	210.00
IUUC-Fso-038170	Fusarium solani	34.34	3.00e-57	216.00
IUUC-Gmo-039499	Gadus morhua	79.62	0.00e+00	782.00
IUUC-Ggr-040042	Gaeumannomyces graminis	35.77	4.00e-64	239.00
IUUC-Gga-040571	Gallus gallus	60.33	0.00e+00	860.00
IUUC-Gac-041345	Gasterosteus aculeatus	77.16	0.00e+00	1120.00
IUUC-Gma-043436	Glycine max	34.11	6.00e-59	221.00
IUUC-Ggo-044652	Gorilla gorilla	58.44	0.00e+00	847.00
IUUC-Hsa-045864	Homo sapiens	58.44	0.00e+00	845.00
IUUC-Hvu-047071	Hordeum vulgare	33.75	2.00e-56	213.00
IUUC-Itr-048216	Ictidomys tridecemlineatus	68.60	0.00e+00	704.00
IUUC-Kpa-049132	Komagataella pastoris	29.08	9.00e-47	181.00
IUUC-Lch-050040	Latimeria chalumnae	61.53	0.00e+00	837.00
IUUC-Lpe-050772	Leersia perrieri	27.92	2.00e-16	80.50
IUUC-Loc-052449	Lepisosteus oculatus	64.59	0.00e+00	966.00
IUUC-Lma-053248	Leptosphaeria maculans	34.09	9.00e-60	225.00
IUUC-Laf-054121	Loxodonta africana	57.46	0.00e+00	810.00
IUUC-Mcc-055514	Macaca mulatta	57.69	0.00e+00	835.00
IUUC-Meu-056873	Macropus eugenii	48.71	6.00e-139	488.00
IUUC-Mor-057243	Magnaporthe oryzae	34.38	8.00e-60	225.00
IUUC-Mpo-057439	Magnaporthe poae	36.04	9.00e-63	235.00
IUUC-Mtr-058457	Medicago truncatula	32.75	2.00e-54	206.00
IUUC-Mla-058958	Melampsora laricipopulina	32.79	2.00e-54	206.00
IUUC-Mga-060157	Meleagris gallopavo	59.95	0.00e+00	862.00
IUUC-Mvi-060442	Microbotryum violaceum	32.31	2.00e-52	201.00
IUUC-Mmr-061062	Microcebus murinus	57.46	0.00e+00	829.00
IUUC-Mdo-062253	Monodelphis domestica	54.20	0.00e+00	765.00
IUUC-Mmu-064050	Mus musculus	56.96	0.00e+00	837.00
IUUC-Mac-065619	Musa acuminata	33.33	2.00e-54	206.00
IUUC-Mpu-066554	Mustela putorius furo	58.17	0.00e+00	812.00
IUUC-Mlu-068003	Myotis lucifugus	56.94	0.00e+00	816.00
IUUC-Nfi-068612	Neosartorya fischeri	33.48	2.00e-61	230.00
IUUC-Ncr-068878	Neurospora crassa	34.19	4.00e-50	193.00
IUUC-Nle-069661	Nomascus leucogenys	58.25	0.00e+00	842.00
IUUC-Opr-070944	Ochotona princeps	72.26	3.00e-130	459.00
IUUC-Ont-071266	Oreochromis niloticus	80.05	0.00e+00	1196.00
IUUC-Oan-073442	Ornithorhynchus anatinus	59.51	0.00e+00	817.00
IUUC-Ocu-073788	Oryctolagus cuniculus	54.60	0.00e+00	739.00
IUUC-Oba-075085	Oryza barthii	31.73	3.00e-36	145.00
IUUC-Obr-076663	Oryza brachyantha	31.44	4.00e-46	179.00
IUUC-Ogl-076937	Oryza glaberrima	30.39	5.00e-51	195.00
IUUC-Ogu-078909	Oryza glumaepatula	30.50	3.00e-48	186.00
IUUC-Oin-079617	Oryza indica	32.00	6.00e-51	195.00
IUUC-Olo-081043	Oryza longistaminata	25.65	3.00e-24	106.00
IUUC-Ome-081646	Oryza meridionalis	24.61	3.00e-23	103.00
IUUC-Oni-082914	Oryza nivara	30.50	2.00e-48	187.00
IUUC-Oru-084878	Oryza rufipogon	30.50	2.00e-48	187.00
IUUC-Osa-085822	Oryza sativa	31.25	4.00e-53	202.00
IUUC-Ola-086931	Oryzias latipes	74.88	0.00e+00	1111.00
IUUC-Oga-088443	Otolemur garnettii	58.06	0.00e+00	841.00
IUUC-Oar-089325	Ovis aries	78.67	0.00e+00	669.00
IUUC-Ptr-091584	Pan troglodytes	56.51	0.00e+00	783.00
IUUC-Pan-092551	Papio anubis	56.31	0.00e+00	807.00
IUUC-Psi-093366	Pelodiscus sinensis	53.89	6.00e-131	461.00
IUUC-Pno-095136	Phaeosphaeria nodorum	32.51	2.00e-50	194.00
IUUC-Ppa-095574	Physcomitrella patens	33.94	6.00e-61	228.00
IUUC-Pfo-097462	Poecilia formosa	78.51	0.00e+00	1161.00
IUUC-Pab-098547	Pongo abelii	57.86	0.00e+00	839.00
IUUC-Pop-099529	Populus trichocarpa	36.02	7.00e-63	234.00
IUUC-Pca-101066	Procavia capensis	81.14	8.00e-126	444.00
IUUC-Ppe-102110	Prunus persica	35.22	1.00e-61	230.00
IUUC-Pva-103015	Pteropus vampyrus	59.47	0.00e+00	733.00
IUUC-Ptt-103998	Puccinia triticina	31.51	7.00e-53	202.00
IUUC-Pte-104417	Pyrenophora teres	35.05	9.00e-58	218.00
IUUC-Pyt-104820	Pyrenophora triticirepentis	35.49	3.00e-57	216.00
IUUC-Rno-105533	Rattus norvegicus	56.02	0.00e+00	838.00
IUUC-Sce-106160	Saccharomyces cerevisiae	26.98	7.00e-40	159.00
IUUC-Sha-106590	Sarcophilus harrisii	57.99	0.00e+00	814.00
IUUC-Sja-107669	Schizosaccharomyces japonicus	34.65	2.00e-55	209.00
IUUC-Spo-108353	Schizosaccharomyces pombe	36.12	4.00e-63	235.00
IUUC-Ssl-108599	Sclerotinia sclerotiorum	35.99	2.00e-58	221.00
IUUC-Smo-108842	Selaginella moellendorffii	35.36	1.00e-36	146.00
IUUC-Sit-110781	Setaria italica	33.67	3.00e-56	213.00
IUUC-Sly-111797	Solanum lycopersicum	33.93	2.00e-56	213.00
IUUC-Stu-112188	Solanum tuberosum	35.03	1.00e-60	227.00
IUUC-Sbi-114862	Sorghum bicolor	31.01	4.00e-45	176.00
IUUC-Sre-115162	Sporisorium reilianum	35.37	3.00e-67	250.00
IUUC-Ssc-115505	Sus scrofa	82.26	7.00e-144	503.00
IUUC-Tgu-116535	Taeniopygia guttata	59.17	0.00e+00	858.00
IUUC-Tni-120200	Tetraodon nigroviridis	83.78	0.00e+00	1303.00
IUUC-Tca-121548	Theobroma cacao	34.59	5.00e-46	179.00
IUUC-Tre-122124	Trichoderma reesei	34.62	1.00e-59	224.00
IUUC-Tvi-122457	Trichoderma virens	31.02	3.00e-55	210.00
IUUC-Tae-125646	Triticum aestivum	34.34	6.00e-59	222.00
IUUC-Tme-127180	Tuber melanosporum	38.86	6.00e-70	258.00
IUUC-Tbe-127530	Tupaia belangeri	66.00	4.00e-164	571.00
IUUC-Ttr-128549	Tursiops truncatus	52.15	0.00e+00	707.00
IUUC-Uma-129381	Ustilago maydis	35.31	8.00e-68	252.00
IUUC-Vda-129889	Verticillium dahliae	32.98	2.00e-53	204.00
IUUC-Vpa-130100	Vicugna pacos	53.78	0.00e+00	703.00
IUUC-Vvi-131366	Vitis vinifera	36.04	6.00e-64	238.00
IUUC-Xtr-132048	Xenopus tropicalis	65.75	0.00e+00	749.00
IUUC-Xma-133593	Xiphophorus maculatus	78.85	0.00e+00	1141.00
IUUC-Yli-134338	Yarrowia lipolytica	28.11	1.00e-34	141.00
IUUC-Zma-135586	Zea mays	32.00	8.00e-51	194.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence