iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000002686.3	ENSMMUT00000060549.1	ENSMMUP00000054147.1
ENSMMUG00000002686.3	ENSMMUT00000046303.2	ENSMMUP00000039345.1
ENSMMUG00000002686.3	ENSMMUT00000003826.3	ENSMMUP00000003617.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.50e-09	37.3	105	144

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl++f++  ++ +C H f++ C+q w      s++++ CPlC+
   Q: 105  CPICLDRFDNVSYLDRCLHKFCFRCVQEW------SKNKAECPLCK 144
           **********999999*************......**********7 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MGRGSQPPLG SPLSREEGEA PPPAPASEGR RRSRRVRLRG SCRHRPSFLG CRELVASAPA 60
RPAPASSEIM ASAAKEFKMD NFSPKAGTSK LQQTVPADAS PDSKCPICLD RFDNVSYLDR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGGAGTGA AATGCTTAAT TCAGGAATGG ATTTTGGAGT TTCTGGGTGC TGAAGAAGTA 60
GAGCCTTTCT GCCTGCAGGC CCAGTGAGTC GACACGGTGG GGGCCCGCGA GCCCCGGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000930--C:gamma-tubulin complex
GO:0016607--C:nuclear speck
GO:0032391--C:photoreceptor connecting cilium
GO:0016605--C:PML body
GO:0000922--C:spindle pole
GO:0000151--C:ubiquitin ligase complex
GO:0003823--F:antigen binding
GO:0003677--F:DNA binding
GO:0019789--F:SUMO transferase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0051457--P:maintenance of protein location in nucleus
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0042127--P:regulation of cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000940	Aegilops tauschii	36.76	3.00e-09	55.80
IUUC-Aml-002240	Ailuropoda melanoleuca	89.98	0.00e+00	902.00
IUUC-Atr-002964	Amborella trichopoda	30.16	3.00e-11	62.00
IUUC-Apl-003666	Anas platyrhynchos	58.57	3.00e-144	506.00
IUUC-Aca-005305	Anolis carolinensis	63.24	2.00e-149	523.00
IUUC-Aly-005926	Arabidopsis lyrata	36.56	8.00e-13	67.40
IUUC-Ath-007299	Arabidopsis thaliana	36.17	8.00e-12	63.90
IUUC-Ame-011109	Astyanax mexicanus	53.59	7.00e-115	408.00
IUUC-Bta-012637	Bos taurus	91.01	0.00e+00	917.00
IUUC-Bdi-014270	Brachypodium distachyon	40.00	2.00e-11	62.80
IUUC-Bol-015307	Brassica oleracea	34.41	2.00e-10	59.70
IUUC-Bra-017451	Brassica rapa	31.25	3.00e-08	52.40
IUUC-Cja-019105	Callithrix jacchus	96.59	0.00e+00	1020.00
IUUC-Cfa-021203	Canis familiaris	91.50	0.00e+00	912.00
IUUC-Cpo-022335	Cavia porcellus	86.03	0.00e+00	875.00
IUUC-Csa-023870	Chlorocebus sabaeus	99.66	0.00e+00	1033.00
IUUC-Cho-024870	Choloepus hoffmanni	91.77	0.00e+00	886.00
IUUC-Cne-026788	Cryptococcus neoformans	33.85	5.00e-07	50.10
IUUC-Dre-027535	Danio rerio	51.62	2.00e-121	430.00
IUUC-Dno-028963	Dasypus novemcinctus	91.71	0.00e+00	897.00
IUUC-Dor-030239	Dipodomys ordii	90.37	0.00e+00	807.00
IUUC-Dme-031941	Drosophila melanogaster	31.72	4.00e-36	147.00
IUUC-Ete-032300	Echinops telfairi	84.71	0.00e+00	1119.00
IUUC-Eca-033690	Equus caballus	94.10	0.00e+00	913.00
IUUC-Eeu-035257	Erinaceus europaeus	87.68	0.00e+00	875.00
IUUC-Fca-036383	Felis catus	90.41	0.00e+00	907.00
IUUC-Fal-037209	Ficedula albicollis	62.83	5.00e-164	572.00
IUUC-Gmo-039416	Gadus morhua	53.40	2.00e-118	419.00
IUUC-Gga-041267	Gallus gallus	71.90	3.00e-172	599.00
IUUC-Gac-042227	Gasterosteus aculeatus	52.42	7.00e-116	410.00
IUUC-Gma-042777	Glycine max	36.47	1.00e-08	53.90
IUUC-Ggo-044445	Gorilla gorilla	98.98	0.00e+00	1047.00
IUUC-Hsa-045844	Homo sapiens	99.15	0.00e+00	1049.00
IUUC-Hvu-047531	Hordeum vulgare	46.00	1.00e-10	57.00
IUUC-Itr-048818	Ictidomys tridecemlineatus	92.02	0.00e+00	935.00
IUUC-Lch-050031	Latimeria chalumnae	65.92	5.00e-169	588.00
IUUC-Lpe-051274	Leersia perrieri	37.74	1.00e-08	53.50
IUUC-Loc-052944	Lepisosteus oculatus	58.40	5.00e-143	501.00
IUUC-Laf-053820	Loxodonta africana	93.49	0.00e+00	869.00
IUUC-Meu-056806	Macropus eugenii	71.83	0.00e+00	636.00
IUUC-Mtr-058378	Medicago truncatula	36.04	4.00e-12	65.10
IUUC-Mla-059017	Melampsora laricipopulina	36.07	4.00e-09	55.80
IUUC-Mvi-060417	Microbotryum violaceum	25.62	5.00e-17	83.20
IUUC-Mmr-061481	Microcebus murinus	94.24	0.00e+00	927.00
IUUC-Mdo-062219	Monodelphis domestica	76.67	2.00e-109	390.00
IUUC-Mmu-064138	Mus musculus	89.20	0.00e+00	835.00
IUUC-Mlu-067088	Myotis lucifugus	91.69	0.00e+00	934.00
IUUC-Nle-069862	Nomascus leucogenys	99.18	0.00e+00	1073.00
IUUC-Opr-071076	Ochotona princeps	90.33	0.00e+00	815.00
IUUC-Ont-072225	Oreochromis niloticus	52.38	1.00e-111	397.00
IUUC-Oan-073069	Ornithorhynchus anatinus	66.29	2.00e-156	545.00
IUUC-Ocu-074826	Oryctolagus cuniculus	92.71	0.00e+00	947.00
IUUC-Oba-075429	Oryza barthii	37.68	2.00e-10	60.10
IUUC-Obr-076084	Oryza brachyantha	36.23	4.00e-10	58.20
IUUC-Ogl-077444	Oryza glaberrima	37.68	2.00e-10	59.70
IUUC-Ogu-078603	Oryza glumaepatula	37.68	2.00e-10	60.10
IUUC-Oin-079777	Oryza indica	37.68	2.00e-10	59.70
IUUC-Oni-082396	Oryza nivara	37.68	2.00e-10	60.10
IUUC-Opu-083698	Oryza punctata	36.62	9.00e-10	57.80
IUUC-Oru-084305	Oryza rufipogon	37.68	2.00e-10	59.70
IUUC-Ola-087377	Oryzias latipes	54.38	9.00e-108	383.00
IUUC-Oga-088059	Otolemur garnettii	90.82	0.00e+00	918.00
IUUC-Oar-089592	Ovis aries	91.60	0.00e+00	887.00
IUUC-Ptr-091233	Pan troglodytes	98.64	0.00e+00	1044.00
IUUC-Pan-092743	Papio anubis	100.00	0.00e+00	1035.00
IUUC-Psi-093669	Pelodiscus sinensis	60.80	0.00e+00	853.00
IUUC-Ppa-095668	Physcomitrella patens	27.13	1.00e-20	94.00
IUUC-Pfo-096706	Poecilia formosa	52.99	2.00e-106	379.00
IUUC-Pop-098813	Populus trichocarpa	24.49	7.00e-13	67.80
IUUC-Pca-100967	Procavia capensis	90.93	0.00e+00	820.00
IUUC-Ppe-101922	Prunus persica	35.06	1.00e-08	53.90
IUUC-Pva-102982	Pteropus vampyrus	94.06	0.00e+00	923.00
IUUC-Pgr-103551	Puccinia graminis	38.46	9.00e-09	53.90
IUUC-Ptt-103977	Puccinia triticina	33.33	6.00e-08	51.20
IUUC-Rno-105730	Rattus norvegicus	88.58	0.00e+00	790.00
IUUC-Sha-106588	Sarcophilus harrisii	68.26	5.00e-179	621.00
IUUC-Sja-107735	Schizosaccharomyces japonicus	35.38	2.00e-07	49.30
IUUC-Smo-109039	Selaginella moellendorffii	24.46	4.00e-17	82.40
IUUC-Sly-111835	Solanum lycopersicum	42.37	1.00e-08	55.50
IUUC-Stu-111938	Solanum tuberosum	31.91	7.00e-07	47.80
IUUC-Sar-113622	Sorex araneus	89.23	2.00e-162	566.00
IUUC-Sre-115041	Sporisorium reilianum	37.84	1.00e-09	57.00
IUUC-Ssc-115244	Sus scrofa	94.41	0.00e+00	885.00
IUUC-Tgu-117180	Taeniopygia guttata	64.85	4.00e-173	602.00
IUUC-Tru-118393	Takifugu rubripes	53.46	4.00e-120	425.00
IUUC-Tsy-119408	Tarsius syrichta	93.75	0.00e+00	939.00
IUUC-Tni-120664	Tetraodon nigroviridis	49.06	1.00e-120	427.00
IUUC-Tca-121712	Theobroma cacao	27.22	6.00e-16	78.20
IUUC-Tae-122787	Triticum aestivum	38.57	1.00e-10	60.10
IUUC-Tbe-127301	Tupaia belangeri	85.23	0.00e+00	846.00
IUUC-Ttr-128204	Tursiops truncatus	92.16	0.00e+00	951.00
IUUC-Uma-129420	Ustilago maydis	43.06	1.00e-09	57.40
IUUC-Vpa-130297	Vicugna pacos	94.15	0.00e+00	911.00
IUUC-Vvi-131157	Vitis vinifera	25.84	4.00e-17	82.00
IUUC-Xtr-132845	Xenopus tropicalis	67.44	1.00e-169	590.00
IUUC-Xma-133439	Xiphophorus maculatus	53.78	1.00e-108	387.00
IUUC-Yli-134652	Yarrowia lipolytica	38.78	5.00e-06	46.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence