iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028478

UUCD1 version

UUC-DaR-01262

Ensembl Protein ID

ENSDARP00000111963.1

UniProt Accession

Q6PH57; GBB1_DANRE

Genbank Protein ID

AAH56708.1; AAH71277.1

Protein Name

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Transducin beta chain 1

Genbank Nucleotide ID

BC056708; BC071277

Gene Name

gnb1a; gnb1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000090454.2	ENSDART00000130104.2	ENSDARP00000111963.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.80e-43	143.7	224	259
UBD/Beta-Prp	4.60e-87	292.9	103	340

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gH++++++++f ++ + +++GsdD t++++Dlr + 
   Q: 224  GHESDINAICFfPNgNAFATGSDDATCRLFDLRADQ 259
           8*********99777*****************9875 PP

UBD/Beta-Prp

   S: 16   vkfspdksllatgsrdgtikvwdvttgkl....lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlsl 100
            +++p+++++a g+ d+   +++++t        r+l gh++  ++++f +d   +vt+s D t  +wd++tg+++ t+ gh+ +v+sl
   Q: 103  CAYAPSGNYVACGGLDNICSIYNLKTREGnvrvSRELAGHTGYLSCCRFLDDN-QIVTSSGDTTCALWDIETGQQTTTFAGHTGDVMSL 190
           4678*******************9997667798999****************7.7********************************** PP
   S: 101  sfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsf 188
           s+ p++  +vsG  d  +++wd+++g c + t++gh++ +n +++ p+gn +++Gs+D t+rl+dl+ ++ l      +    ++s++f
   Q: 191  SLAPDTRLFVSGACDASAKLWDVREGMCRQ-TFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMVYsHDNIICGITSVAF 278
           ******************************.***********************************988888877334456799***** PP
   S: 189  dsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWd 250
           +++g+ l++g +d   ++wd  + +    l gh++ v+++ +++++  +++gs D  ++iW+
   Q: 279  SKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
           *************************************************************8 PP

Organism

Danio rerio

Functional Description
(View)

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity).

Protein Sequence
(Fasta)

MSELDQLRQE AEQLKNQIRD ARKACADATL SQITANIDPV GRIQMRTRRT LRGHLAKIYA 60
MHWGTDSRLL VSASQDGKLI IWDSYTTNKV HAIPLRSSWV MTCAYAPSGN YVACGGLDNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGCGAGAG CCTGACACAC CGAACGCACA AGAAGCTCTC CAGCGCCCGC GGACGACCAG 60
TGTGGAGCTA CCGAAAGACG AAAATCTGGA CCGAGCCGCC TTCAGCACCG GGAATCAGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0807--Transducer
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0004871--F:signal transducer activity
GO:0048920--P:posterior lateral line neuromast primordium migration

KEGG

dre:322104

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001337	Ailuropoda melanoleuca	98.82	0.00e+00	666.00
IUUC-Atr-002610	Amborella trichopoda	49.68	1.00e-87	316.00
IUUC-Apl-003811	Anas platyrhynchos	98.53	0.00e+00	664.00
IUUC-Ago-007831	Ashbya gossypii	38.24	5.00e-69	255.00
IUUC-Acl-008154	Aspergillus clavatus	69.14	2.00e-142	498.00
IUUC-Afl-008568	Aspergillus flavus	69.41	4.00e-144	504.00
IUUC-Afu-008789	Aspergillus fumigatus	69.14	3.00e-142	498.00
IUUC-Ani-009213	Aspergillus nidulans	69.12	2.00e-142	498.00
IUUC-Ang-009836	Aspergillus niger	69.12	1.00e-143	502.00
IUUC-Aor-010165	Aspergillus oryzae	69.41	4.00e-144	504.00
IUUC-Ate-010520	Aspergillus terreus	63.01	5.00e-113	400.00
IUUC-Ame-011092	Astyanax mexicanus	99.41	0.00e+00	700.00
IUUC-Bgr-012079	Blumeria graminis	67.85	1.00e-135	476.00
IUUC-Bta-012709	Bos taurus	98.82	0.00e+00	666.00
IUUC-Bci-013621	Botrytis cinerea	68.51	4.00e-134	471.00
IUUC-Cja-019782	Callithrix jacchus	98.82	0.00e+00	666.00
IUUC-Cfa-020111	Canis familiaris	98.82	0.00e+00	666.00
IUUC-Cpo-022494	Cavia porcellus	98.82	0.00e+00	666.00
IUUC-Csa-023672	Chlorocebus sabaeus	98.82	0.00e+00	666.00
IUUC-Cin-025309	Ciona intestinalis	80.18	4.00e-171	593.00
IUUC-Csv-026258	Ciona savignyi	80.47	1.00e-170	592.00
IUUC-Cgl-026673	Colletotrichum gloeosporioides	67.25	5.00e-138	483.00
IUUC-Dse-031388	Dothistroma septosporum	68.82	6.00e-142	496.00
IUUC-Ete-032710	Echinops telfairi	89.61	2.00e-168	584.00
IUUC-Eca-033359	Equus caballus	98.53	0.00e+00	665.00
IUUC-Fal-037004	Ficedula albicollis	98.53	0.00e+00	664.00
IUUC-Fox-037946	Fusarium oxysporum	67.25	8.00e-133	466.00
IUUC-Fso-038136	Fusarium solani	67.25	8.00e-133	466.00
IUUC-Gmo-039709	Gadus morhua	99.41	0.00e+00	701.00
IUUC-Ggr-039969	Gaeumannomyces graminis	67.25	3.00e-137	481.00
IUUC-Gga-041163	Gallus gallus	98.46	0.00e+00	634.00
IUUC-Gac-041386	Gasterosteus aculeatus	98.82	0.00e+00	698.00
IUUC-Gma-043322	Glycine max	46.43	1.00e-91	330.00
IUUC-Ggo-045261	Gorilla gorilla	98.45	0.00e+00	627.00
IUUC-Hsa-046450	Homo sapiens	98.82	0.00e+00	666.00
IUUC-Itr-049064	Ictidomys tridecemlineatus	98.82	0.00e+00	666.00
IUUC-Kpa-049192	Komagataella pastoris	39.44	3.00e-64	239.00
IUUC-Lma-052985	Leptosphaeria maculans	68.56	1.00e-139	489.00
IUUC-Laf-054222	Loxodonta africana	98.82	0.00e+00	666.00
IUUC-Mcc-054970	Macaca mulatta	98.82	0.00e+00	666.00
IUUC-Mor-057188	Magnaporthe oryzae	66.96	2.00e-136	479.00
IUUC-Mpo-057544	Magnaporthe poae	66.96	9.00e-138	483.00
IUUC-Mmr-061302	Microcebus murinus	98.53	0.00e+00	665.00
IUUC-Mdo-062044	Monodelphis domestica	99.41	0.00e+00	671.00
IUUC-Mmu-063323	Mus musculus	98.82	0.00e+00	666.00
IUUC-Mac-064871	Musa acuminata	45.94	4.00e-85	308.00
IUUC-Mlu-067309	Myotis lucifugus	98.82	0.00e+00	666.00
IUUC-Nfi-068332	Neosartorya fischeri	69.14	6.00e-142	497.00
IUUC-Ncr-068650	Neurospora crassa	66.08	3.00e-130	458.00
IUUC-Nle-069791	Nomascus leucogenys	98.82	0.00e+00	666.00
IUUC-Oan-072780	Ornithorhynchus anatinus	98.82	0.00e+00	668.00
IUUC-Ocu-073769	Oryctolagus cuniculus	98.82	0.00e+00	666.00
IUUC-Oga-087961	Otolemur garnettii	98.82	0.00e+00	666.00
IUUC-Pan-092079	Papio anubis	98.82	0.00e+00	666.00
IUUC-Psi-093225	Pelodiscus sinensis	98.53	0.00e+00	664.00
IUUC-Pma-094748	Petromyzon marinus	92.46	3.00e-141	494.00
IUUC-Pno-095135	Phaeosphaeria nodorum	68.56	2.00e-139	488.00
IUUC-Ppa-095726	Physcomitrella patens	44.12	6.00e-76	277.00
IUUC-Pab-098658	Pongo abelii	98.82	0.00e+00	666.00
IUUC-Pop-099370	Populus trichocarpa	51.61	5.00e-90	324.00
IUUC-Pca-100313	Procavia capensis	98.24	0.00e+00	655.00
IUUC-Pva-102636	Pteropus vampyrus	98.53	0.00e+00	665.00
IUUC-Pte-104053	Pyrenophora teres	67.55	7.00e-140	489.00
IUUC-Pyt-104426	Pyrenophora triticirepentis	63.42	2.00e-127	448.00
IUUC-Rno-105112	Rattus norvegicus	98.82	0.00e+00	666.00
IUUC-Sha-106856	Sarcophilus harrisii	99.41	0.00e+00	671.00
IUUC-Ssl-108539	Sclerotinia sclerotiorum	68.71	4.00e-134	470.00
IUUC-Smo-109652	Selaginella moellendorffii	43.58	4.00e-75	275.00
IUUC-Sly-111784	Solanum lycopersicum	50.97	1.00e-86	313.00
IUUC-Stu-112400	Solanum tuberosum	50.97	7.00e-87	314.00
IUUC-Sar-113642	Sorex araneus	92.28	3.00e-151	527.00
IUUC-Tgu-116775	Taeniopygia guttata	98.46	0.00e+00	633.00
IUUC-Tre-122156	Trichoderma reesei	66.96	3.00e-137	481.00
IUUC-Tvi-122640	Trichoderma virens	66.96	3.00e-137	481.00
IUUC-Tae-124407	Triticum aestivum	50.96	1.00e-87	316.00
IUUC-Tme-126886	Tuber melanosporum	70.36	1.00e-139	489.00
IUUC-Tbe-127694	Tupaia belangeri	69.35	1.00e-132	466.00
IUUC-Vda-129855	Verticillium dahliae	71.80	8.00e-132	463.00
IUUC-Vvi-131162	Vitis vinifera	51.61	6.00e-90	324.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence