iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036706

Ensembl Protein ID

ENSFALP00000010114.1

UniProt Accession

U3K510; U3K510_FICAL

Genbank Protein ID

ENSFALP00000010114

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01011329

Gene Name

STRAP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000009695.1	ENSFALT00000010154.1	ENSFALP00000010114.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-25	87.6	250	284
UBD/Beta-Prp	3.60e-40	137.7	35	286

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtll.vsGsdDgtikvWDlrtg 33
           gH ++++c++f +d+ l +sGs Dgt+++W ++ g
   Q: 250  GHFGPIHCVRFsPDGELyASGSEDGTLRLWQTTVG 284
           799*********997776************98765 PP

UBD/Beta-Prp

   S: 41   tgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcl 129
           tg+ + ++ gh+++v+  +++ d+   +t++ D t+kvwd  +g+ ++tl  h++ v s++f +++++l++G++d+ +r++dl++ +  
   Q: 35   TGDWIGTFLGHKGAVWGATLNTDATKAATAAADFTAKVWDAVSGDELITLA-HKHIVKSVDFTQDSNYLLTGGQDKLLRIYDLSKPEAE 122
           667799*********************************************.************************************* PP
   S: 130  eetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng.......................... 192
            ++ sgh++ +  + +++d++ + s ++D+tvrlWd +t++ ++ l      sv s+++ ++g                          
   Q: 123  PDVVSGHTSGIKKALWSSDDKQILS-ADDKTVRLWDRSTMTEVKSLN--VAMSVSSMEYVPEGqilvitygktiafhsaetleqiksfe 208
           ******************9987766.69*********9999999994..6899999998888888888888888888888999999999 PP
   S: 193  ..............kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdl 256
                         ++lv+g++d ++  +d+ tge +++++gh  ++ +vrfsp++e+++sgs+Dg++r+W ++ g++
   Q: 209  apatinsaslhpakECLVAGGEDFKLYKYDYNTGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTTVGKT 286
           99999999999999*********************************************************8776665 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MFFSFKNLFP PFPVLPECWF CSGEDGKPML RQGDTGDWIG TFLGHKGAVW GATLNTDATK 60
AATAAADFTA KVWDAVSGDE LITLAHKHIV KSVDFTQDSN YLLTGGQDKL LRIYDLSKPE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGAGCCCGC GTGCCCCGGC CGGCTCCCGG CTCCGGAGGG CGGGAGGTGC CCCGGGTGGG 60
GTGCGTGTAA AACTTCTGTC CCGCCGCCTG TGCACATGGG CTGTGGGTTT AAAGAGAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0032797--C:SMN complex
GO:0034719--C:SMN-Sm protein complex
GO:0003723--F:RNA binding
GO:0030277--P:maintenance of gastrointestinal epithelium
GO:0010633--P:negative regulation of epithelial cell migration
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0010719--P:negative regulation of epithelial to mesenchymal transition
GO:0060394--P:negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030512--P:negative regulation of transforming growth factor beta receptor signaling pathway
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000668	Aegilops tauschii	46.15	4.00e-63	234.00
IUUC-Aml-002091	Ailuropoda melanoleuca	87.22	6.00e-142	496.00
IUUC-Atr-002571	Amborella trichopoda	48.54	5.00e-65	241.00
IUUC-Apl-003327	Anas platyrhynchos	97.14	2.00e-157	548.00
IUUC-Aca-005324	Anolis carolinensis	89.81	1.00e-150	525.00
IUUC-Aly-006452	Arabidopsis lyrata	45.59	4.00e-63	234.00
IUUC-Ath-006646	Arabidopsis thaliana	45.59	3.00e-63	234.00
IUUC-Acl-008014	Aspergillus clavatus	39.67	1.00e-38	153.00
IUUC-Afu-008942	Aspergillus fumigatus	33.46	7.00e-26	110.00
IUUC-Ani-009394	Aspergillus nidulans	39.53	4.00e-39	154.00
IUUC-Ang-009593	Aspergillus niger	35.61	2.00e-24	106.00
IUUC-Aor-010206	Aspergillus oryzae	40.79	1.00e-39	156.00
IUUC-Ame-011328	Astyanax mexicanus	78.91	2.00e-116	411.00
IUUC-Bgr-012308	Blumeria graminis	39.62	2.00e-46	179.00
IUUC-Bta-013429	Bos taurus	86.94	2.00e-141	494.00
IUUC-Bci-013803	Botrytis cinerea	40.51	7.00e-45	174.00
IUUC-Bdi-014996	Brachypodium distachyon	45.59	4.00e-63	234.00
IUUC-Bol-016595	Brassica oleracea	46.52	4.00e-65	241.00
IUUC-Bra-017775	Brassica rapa	45.45	8.00e-64	238.00
IUUC-Cja-018740	Callithrix jacchus	86.22	4.00e-140	490.00
IUUC-Cfa-021145	Canis familiaris	86.62	7.00e-142	496.00
IUUC-Cpo-022373	Cavia porcellus	86.62	2.00e-141	494.00
IUUC-Cre-022806	Chlamydomonas reinhardtii	43.87	5.00e-51	194.00
IUUC-Csa-023098	Chlorocebus sabaeus	85.99	1.00e-139	488.00
IUUC-Cho-024856	Choloepus hoffmanni	78.03	1.00e-117	416.00
IUUC-Cin-025541	Ciona intestinalis	56.30	4.00e-87	314.00
IUUC-Csv-026287	Ciona savignyi	55.08	8.00e-78	283.00
IUUC-Cgl-026513	Colletotrichum gloeosporioides	40.00	2.00e-43	169.00
IUUC-Cne-026869	Cryptococcus neoformans	45.55	7.00e-58	217.00
IUUC-Dre-028457	Danio rerio	79.49	4.00e-118	417.00
IUUC-Dno-029213	Dasypus novemcinctus	86.62	8.00e-142	496.00
IUUC-Dse-031350	Dothistroma septosporum	39.94	2.00e-43	169.00
IUUC-Dme-031857	Drosophila melanogaster	60.44	2.00e-88	318.00
IUUC-Ete-032558	Echinops telfairi	77.48	2.00e-86	311.00
IUUC-Eca-033934	Equus caballus	87.58	3.00e-142	497.00
IUUC-Eeu-034650	Erinaceus europaeus	85.34	3.00e-124	437.00
IUUC-Fca-035909	Felis catus	86.62	2.00e-140	491.00
IUUC-Fox-037780	Fusarium oxysporum	41.55	6.00e-43	167.00
IUUC-Fso-038197	Fusarium solani	40.67	3.00e-45	175.00
IUUC-Gmo-039707	Gadus morhua	75.45	2.00e-110	391.00
IUUC-Ggr-040054	Gaeumannomyces graminis	39.26	6.00e-45	174.00
IUUC-Gga-040901	Gallus gallus	98.09	8.00e-159	552.00
IUUC-Gac-041876	Gasterosteus aculeatus	79.71	3.00e-118	417.00
IUUC-Gma-044014	Glycine max	48.54	2.00e-65	242.00
IUUC-Ggo-044583	Gorilla gorilla	79.37	5.00e-124	437.00
IUUC-Hsa-046553	Homo sapiens	85.94	2.00e-139	488.00
IUUC-Hvu-047544	Hordeum vulgare	46.52	1.00e-63	236.00
IUUC-Itr-047980	Ictidomys tridecemlineatus	86.94	3.00e-142	497.00
IUUC-Lch-050078	Latimeria chalumnae	77.78	5.00e-127	446.00
IUUC-Lpe-051246	Leersia perrieri	46.52	2.00e-64	239.00
IUUC-Loc-052598	Lepisosteus oculatus	73.97	2.00e-120	424.00
IUUC-Lma-053226	Leptosphaeria maculans	44.84	3.00e-47	181.00
IUUC-Laf-054053	Loxodonta africana	86.94	7.00e-142	496.00
IUUC-Mcc-054652	Macaca mulatta	86.35	6.00e-140	489.00
IUUC-Mor-057256	Magnaporthe oryzae	37.00	2.00e-42	165.00
IUUC-Mpo-057303	Magnaporthe poae	39.00	8.00e-45	174.00
IUUC-Mtr-058421	Medicago truncatula	47.81	2.00e-65	241.00
IUUC-Mla-059073	Melampsora laricipopulina	44.88	3.00e-52	198.00
IUUC-Mga-059664	Meleagris gallopavo	98.41	3.00e-159	554.00
IUUC-Mvi-060534	Microbotryum violaceum	37.30	3.00e-34	139.00
IUUC-Mmr-061044	Microcebus murinus	87.54	4.00e-136	476.00
IUUC-Mdo-063019	Monodelphis domestica	85.99	2.00e-141	495.00
IUUC-Mmu-064092	Mus musculus	87.90	3.00e-142	497.00
IUUC-Mac-065143	Musa acuminata	48.72	3.00e-64	238.00
IUUC-Mpu-066557	Mustela putorius furo	86.94	3.00e-142	497.00
IUUC-Mlu-068179	Myotis lucifugus	86.62	3.00e-141	494.00
IUUC-Nfi-068553	Neosartorya fischeri	39.67	4.00e-38	151.00
IUUC-Ncr-068934	Neurospora crassa	37.46	2.00e-38	152.00
IUUC-Nle-069482	Nomascus leucogenys	86.22	5.00e-139	486.00
IUUC-Opr-071055	Ochotona princeps	65.29	8.00e-92	330.00
IUUC-Ont-072663	Oreochromis niloticus	72.73	7.00e-114	403.00
IUUC-Ocu-074942	Oryctolagus cuniculus	87.26	1.00e-141	495.00
IUUC-Oba-075160	Oryza barthii	46.52	1.00e-64	239.00
IUUC-Obr-076864	Oryza brachyantha	46.52	2.00e-64	239.00
IUUC-Ogl-077076	Oryza glaberrima	46.52	2.00e-64	239.00
IUUC-Ogu-078591	Oryza glumaepatula	46.52	1.00e-64	239.00
IUUC-Oin-079631	Oryza indica	46.15	1.00e-63	236.00
IUUC-Olo-080389	Oryza longistaminata	42.92	5.00e-49	187.00
IUUC-Ome-081693	Oryza meridionalis	46.07	1.00e-62	232.00
IUUC-Oni-082190	Oryza nivara	46.89	1.00e-64	239.00
IUUC-Opu-084163	Oryza punctata	46.52	1.00e-64	239.00
IUUC-Oru-084730	Oryza rufipogon	46.52	1.00e-64	239.00
IUUC-Osa-086010	Oryza sativa	46.52	2.00e-64	239.00
IUUC-Ola-086704	Oryzias latipes	71.25	6.00e-119	420.00
IUUC-Olu-087796	Ostreococcus lucimarinus	50.76	8.00e-67	246.00
IUUC-Oga-088932	Otolemur garnettii	63.21	9.00e-85	306.00
IUUC-Oar-090398	Ovis aries	87.26	1.00e-141	495.00
IUUC-Ptr-091202	Pan troglodytes	85.67	2.00e-139	488.00
IUUC-Pan-091948	Papio anubis	86.31	9.00e-140	489.00
IUUC-Psi-093863	Pelodiscus sinensis	88.89	2.00e-151	528.00
IUUC-Pma-094255	Petromyzon marinus	77.66	1.00e-117	415.00
IUUC-Pno-095075	Phaeosphaeria nodorum	45.88	8.00e-49	187.00
IUUC-Ppa-095206	Physcomitrella patens	47.48	9.00e-69	253.00
IUUC-Pfo-096438	Poecilia formosa	73.65	1.00e-117	416.00
IUUC-Pab-097994	Pongo abelii	85.35	2.00e-139	488.00
IUUC-Pop-099172	Populus trichocarpa	47.62	2.00e-64	239.00
IUUC-Pca-100761	Procavia capensis	76.82	1.00e-114	405.00
IUUC-Ppe-102035	Prunus persica	48.54	5.00e-63	234.00
IUUC-Pva-102794	Pteropus vampyrus	78.03	8.00e-122	429.00
IUUC-Pgr-103581	Puccinia graminis	44.59	6.00e-53	200.00
IUUC-Ptt-103862	Puccinia triticina	44.37	5.00e-52	197.00
IUUC-Pte-104245	Pyrenophora teres	46.24	9.00e-50	190.00
IUUC-Pyt-104537	Pyrenophora triticirepentis	46.24	9.00e-50	190.00
IUUC-Rno-105712	Rattus norvegicus	87.58	5.00e-142	496.00
IUUC-Sha-107568	Sarcophilus harrisii	85.67	2.00e-141	494.00
IUUC-Ssl-108655	Sclerotinia sclerotiorum	39.55	6.00e-43	167.00
IUUC-Smo-108784	Selaginella moellendorffii	51.28	2.00e-70	258.00
IUUC-Sit-109807	Setaria italica	47.62	1.00e-65	243.00
IUUC-Sly-111555	Solanum lycopersicum	46.15	8.00e-63	233.00
IUUC-Stu-111953	Solanum tuberosum	45.42	5.00e-62	231.00
IUUC-Sar-113491	Sorex araneus	79.17	1.00e-106	378.00
IUUC-Sbi-114290	Sorghum bicolor	47.62	1.00e-65	243.00
IUUC-Sre-115008	Sporisorium reilianum	40.21	1.00e-50	192.00
IUUC-Ssc-116392	Sus scrofa	86.86	1.00e-140	492.00
IUUC-Tgu-116835	Taeniopygia guttata	99.68	6.00e-157	546.00
IUUC-Tru-117558	Takifugu rubripes	71.52	2.00e-117	414.00
IUUC-Tsy-119522	Tarsius syrichta	83.76	1.00e-129	455.00
IUUC-Tni-120330	Tetraodon nigroviridis	78.68	2.00e-111	395.00
IUUC-Tca-121759	Theobroma cacao	49.27	9.00e-65	240.00
IUUC-Tre-122163	Trichoderma reesei	41.28	3.00e-43	168.00
IUUC-Tvi-122609	Trichoderma virens	43.29	2.00e-45	176.00
IUUC-Tae-123053	Triticum aestivum	46.15	5.00e-63	234.00
IUUC-Tur-126808	Triticum urartu	46.90	2.00e-61	228.00
IUUC-Tme-127137	Tuber melanosporum	45.45	2.00e-57	215.00
IUUC-Tbe-127324	Tupaia belangeri	72.56	3.00e-76	278.00
IUUC-Ttr-128202	Tursiops truncatus	86.62	3.00e-140	491.00
IUUC-Uma-129433	Ustilago maydis	40.21	6.00e-49	187.00
IUUC-Vda-129675	Verticillium dahliae	36.96	2.00e-41	162.00
IUUC-Vpa-130382	Vicugna pacos	87.26	7.00e-142	496.00
IUUC-Vvi-130921	Vitis vinifera	48.91	1.00e-66	246.00
IUUC-Xtr-132648	Xenopus tropicalis	66.37	2.00e-107	381.00
IUUC-Xma-133969	Xiphophorus maculatus	68.57	1.00e-108	385.00
IUUC-Yli-134670	Yarrowia lipolytica	33.70	2.00e-34	139.00
IUUC-Zma-135878	Zea mays	47.62	8.00e-66	243.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence