iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-058699

Ensembl Protein ID

AES72502

UniProt Accession

A8W463; A8W463_MEDTR

Genbank Protein ID

ABW70162.1; AES72502.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

EU189948; CM001219

Gene Name

MTR_3g091510

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_3g091510	AES72502	AES72502

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	80.37	9.00e-155	543.00	IUUC-Ath-007192

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Medicago truncatula

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MELDSIECVS SSDGMDEDEI HSHHHHHSEF SSTKARNGGA NINNILGPTA IAPATSVHEL 60
LECPVCTNSM YPPIHQCHNG HTLCSTCKTR VHNRCPTCRQ ELGDIRCLAL EKVAESLELP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGTATCTAA TTTCAGAAAT TTAACGGTTC ATCTTTCATT CTCTTTTTCT CTGTCTTGTT 60
GTTGCACAGA GAAGAGAGAG AAAGAGAAAA ACAGAGAGAC AACGAAGAAA AGAACCTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

mtr:MTR_3g091510

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000061	Aegilops tauschii	76.43	6.00e-124	436.00
IUUC-Aly-006522	Arabidopsis lyrata	80.67	2.00e-156	544.00
IUUC-Ath-007192	Arabidopsis thaliana	80.37	4.00e-156	543.00
IUUC-Bdi-014729	Brachypodium distachyon	78.53	3.00e-155	540.00
IUUC-Bol-015983	Brassica oleracea	78.15	9.00e-153	531.00
IUUC-Bra-016910	Brassica rapa	79.75	3.00e-154	536.00
IUUC-Hvu-047574	Hordeum vulgare	76.43	5.00e-124	436.00
IUUC-Lpe-050879	Leersia perrieri	79.13	5.00e-124	436.00
IUUC-Mac-065670	Musa acuminata	84.31	3.00e-163	566.00
IUUC-Oba-075289	Oryza barthii	91.80	2.00e-142	498.00
IUUC-Ome-081318	Oryza meridionalis	79.92	6.00e-124	436.00
IUUC-Opu-084065	Oryza punctata	79.53	1.00e-123	435.00
IUUC-Ppa-095212	Physcomitrella patens	86.64	5.00e-142	496.00
IUUC-Pop-100033	Populus trichocarpa	84.94	2.00e-163	567.00
IUUC-Ppe-101960	Prunus persica	87.69	1.00e-172	598.00
IUUC-Smo-109412	Selaginella moellendorffii	87.69	1.00e-142	498.00
IUUC-Sly-111259	Solanum lycopersicum	81.27	5.00e-155	539.00
IUUC-Stu-112571	Solanum tuberosum	81.38	3.00e-155	540.00
IUUC-Tca-121517	Theobroma cacao	86.98	4.00e-169	586.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence