iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074679

UUCD1 version

UUC-OrC-00770

Ensembl Protein ID

ENSOCUP00000020321.1

UniProt Accession

G1TTF1; G1TTF1_RABIT

Protein Name

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4

Gene Name

WDR4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000023366.2	ENSOCUT00000026682.1	ENSOCUP00000020321.1
ENSOCUG00000023366.2	ENSOCUT00000034018.1	ENSOCUP00000027067.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.50e-06	26.0	187	226

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd..tllvsGsdDgtikvWDlrtgvllk 37
           gHt+ v+ + f  ++  +ll+s+s+D t+++W++r+g++l+
   Q: 187  GHTEFVSRI-FvvPGhpGLLLSSSGDSTLRLWEYRSGRQLH 226
           577777777.788444599******************9986 PP

Organism

Oryctolagus cuniculus

Functional Description
(View)

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Protein Sequence
(Fasta)

MACSVGLALC GQTLVVRGGS RFLAASTACS DGDSVFTYDC SAAEKTSREN RGEDGQPVDQ 60
GSDTILASTF STSGSHFALT DDSKRLVLFR TKPWQCLSVR TVVRRCTALT FTASEEKVLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGAACCAACA GAAGGAATAC CTTTCTCTCT CTGTGTCTCT CACTGTCTAA CTCTGCCTGT 60
CAAAAAAAAA AAAAAAAAAA GAAAGAAAGA AAGAAAGAAA GAAAGAAAGA AAGAAAGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0008176--F:tRNA (guanine-N7-)-methyltransferase activity

KEGG

ocu:100338122

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000556	Aegilops tauschii	27.80	3.00e-13	69.30
IUUC-Apl-003975	Anas platyrhynchos	58.31	7.00e-124	437.00
IUUC-Aca-005170	Anolis carolinensis	53.08	9.00e-104	370.00
IUUC-Aly-005769	Arabidopsis lyrata	31.40	5.00e-25	108.00
IUUC-Ath-006733	Arabidopsis thaliana	30.99	2.00e-24	106.00
IUUC-Acl-008151	Aspergillus clavatus	34.33	9.00e-14	71.60
IUUC-Afl-008518	Aspergillus flavus	34.43	2.00e-18	86.70
IUUC-Afu-009102	Aspergillus fumigatus	27.30	2.00e-13	70.50
IUUC-Ani-009442	Aspergillus nidulans	29.50	5.00e-15	75.90
IUUC-Aor-010133	Aspergillus oryzae	28.27	2.00e-20	94.00
IUUC-Ate-010465	Aspergillus terreus	29.46	8.00e-15	75.10
IUUC-Ame-010613	Astyanax mexicanus	45.09	7.00e-84	304.00
IUUC-Bgr-012067	Blumeria graminis	26.20	3.00e-18	86.70
IUUC-Bta-012788	Bos taurus	75.97	0.00e+00	628.00
IUUC-Bdi-014458	Brachypodium distachyon	34.01	3.00e-21	95.90
IUUC-Bol-015373	Brassica oleracea	37.84	1.00e-24	108.00
IUUC-Bra-016644	Brassica rapa	38.55	4.00e-23	103.00
IUUC-Cpo-021963	Cavia porcellus	79.63	3.00e-172	597.00
IUUC-Csa-024148	Chlorocebus sabaeus	78.21	5.00e-164	570.00
IUUC-Cne-026834	Cryptococcus neoformans	35.76	3.00e-20	93.20
IUUC-Dre-028427	Danio rerio	45.38	3.00e-90	325.00
IUUC-Dno-028881	Dasypus novemcinctus	67.79	9.00e-154	536.00
IUUC-Dor-030522	Dipodomys ordii	76.52	4.00e-169	587.00
IUUC-Dme-032136	Drosophila melanogaster	35.12	1.00e-22	100.00
IUUC-Fca-035833	Felis catus	75.39	4.00e-168	583.00
IUUC-Fal-037497	Ficedula albicollis	57.10	5.00e-119	420.00
IUUC-Gga-040547	Gallus gallus	56.91	2.00e-125	441.00
IUUC-Gac-041761	Gasterosteus aculeatus	43.16	2.00e-81	296.00
IUUC-Gma-043722	Glycine max	33.47	2.00e-22	100.00
IUUC-Ggo-045340	Gorilla gorilla	77.72	6.00e-175	606.00
IUUC-Hsa-046403	Homo sapiens	77.48	8.00e-174	602.00
IUUC-Hvu-047643	Hordeum vulgare	31.75	2.00e-22	100.00
IUUC-Itr-048103	Ictidomys tridecemlineatus	77.00	8.00e-178	616.00
IUUC-Kpa-049283	Komagataella pastoris	27.14	4.00e-17	82.00
IUUC-Lch-050682	Latimeria chalumnae	53.21	6.00e-112	397.00
IUUC-Lpe-050712	Leersia perrieri	31.87	2.00e-25	110.00
IUUC-Loc-052599	Lepisosteus oculatus	49.87	9.00e-111	393.00
IUUC-Laf-054390	Loxodonta africana	71.19	2.00e-169	588.00
IUUC-Mcc-054747	Macaca mulatta	77.48	2.00e-168	585.00
IUUC-Mtr-058600	Medicago truncatula	38.89	2.00e-25	110.00
IUUC-Mla-059129	Melampsora laricipopulina	26.87	6.00e-15	74.30
IUUC-Mga-059876	Meleagris gallopavo	57.02	2.00e-123	435.00
IUUC-Mvi-060359	Microbotryum violaceum	31.74	4.00e-14	73.20
IUUC-Mmr-061518	Microcebus murinus	76.27	2.00e-178	618.00
IUUC-Mac-065625	Musa acuminata	35.98	3.00e-22	99.80
IUUC-Nfi-068402	Neosartorya fischeri	28.05	4.00e-12	66.20
IUUC-Nle-069914	Nomascus leucogenys	77.97	7.00e-165	573.00
IUUC-Ont-071555	Oreochromis niloticus	40.00	1.00e-73	270.00
IUUC-Oan-072951	Ornithorhynchus anatinus	62.72	4.00e-143	500.00
IUUC-Oba-075355	Oryza barthii	26.60	6.00e-14	72.00
IUUC-Obr-076769	Oryza brachyantha	28.42	7.00e-26	111.00
IUUC-Ogl-077168	Oryza glaberrima	32.06	5.00e-27	115.00
IUUC-Ogu-078275	Oryza glumaepatula	25.62	8.00e-14	71.60
IUUC-Oin-079207	Oryza indica	32.06	5.00e-27	115.00
IUUC-Oni-082437	Oryza nivara	27.27	2.00e-13	70.90
IUUC-Opu-084031	Oryza punctata	29.14	3.00e-25	109.00
IUUC-Oru-084380	Oryza rufipogon	26.60	1.00e-13	71.20
IUUC-Osa-085327	Oryza sativa	32.06	1.00e-26	114.00
IUUC-Ola-086716	Oryzias latipes	43.68	2.00e-75	276.00
IUUC-Olu-087708	Ostreococcus lucimarinus	29.95	5.00e-13	68.60
IUUC-Oar-090239	Ovis aries	79.79	3.00e-173	600.00
IUUC-Ptr-090851	Pan troglodytes	77.97	3.00e-175	607.00
IUUC-Pan-092558	Papio anubis	77.83	5.00e-164	570.00
IUUC-Psi-093792	Pelodiscus sinensis	58.15	2.00e-133	468.00
IUUC-Ppa-095757	Physcomitrella patens	38.67	2.00e-22	100.00
IUUC-Pfo-096465	Poecilia formosa	41.69	2.00e-83	302.00
IUUC-Pab-097722	Pongo abelii	79.18	5.00e-171	593.00
IUUC-Pop-098979	Populus trichocarpa	35.68	7.00e-21	94.70
IUUC-Pca-100753	Procavia capensis	65.05	6.00e-108	384.00
IUUC-Ppe-101515	Prunus persica	36.41	6.00e-22	98.60
IUUC-Sja-107780	Schizosaccharomyces japonicus	26.09	8.00e-13	68.20
IUUC-Spo-108251	Schizosaccharomyces pombe	28.75	6.00e-15	75.10
IUUC-Smo-108938	Selaginella moellendorffii	38.86	5.00e-23	102.00
IUUC-Sit-110020	Setaria italica	31.85	4.00e-24	105.00
IUUC-Sly-111543	Solanum lycopersicum	30.08	2.00e-24	106.00
IUUC-Stu-111925	Solanum tuberosum	30.08	6.00e-24	105.00
IUUC-Sbi-114061	Sorghum bicolor	33.33	1.00e-24	107.00
IUUC-Tgu-117321	Taeniopygia guttata	56.85	2.00e-110	391.00
IUUC-Tru-118454	Takifugu rubripes	42.36	4.00e-77	281.00
IUUC-Tni-119894	Tetraodon nigroviridis	43.12	2.00e-72	265.00
IUUC-Tca-121746	Theobroma cacao	35.94	3.00e-22	99.40
IUUC-Tae-124114	Triticum aestivum	31.39	6.00e-22	98.20
IUUC-Tur-126254	Triticum urartu	27.88	7.00e-16	78.20
IUUC-Tbe-127683	Tupaia belangeri	52.26	2.00e-60	226.00
IUUC-Ttr-129056	Tursiops truncatus	72.57	6.00e-162	563.00
IUUC-Vvi-131428	Vitis vinifera	36.96	5.00e-22	98.60
IUUC-Xma-133605	Xiphophorus maculatus	40.60	2.00e-83	302.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence