iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ata-000561

Ensembl Protein ID

EMT26122

UniProt Accession

M8CG25; M8CG25_AEGTA

Genbank Protein ID

EMT26122.1

Protein Name

Defective in cullin neddylation protein

Genbank Nucleotide ID

KD513967

Gene Name

F775_31377

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
F775_31377	EMT26122	EMT26122

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	3.80e-83	278.9	54	240
UBD/Alpha-Helix/UBA	6.20e-07	30.1	10	46

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkdeqkfkdiYrfaf 102
           ++++le+l++rYk+ + d+i +eg +++c+dl vdp+d+++Lv++w+++aat+cef+r+ef+dgl+++g+dsiekl+ekl++l+ e+kd +kf++iY+faf
   Q: 54   NSRHLEDLYSRYKERDADMIMVEGTSQLCNDLLVDPQDVVMLVISWHMKAATMCEFTRQEFIDGLQSIGVDSIEKLREKLPSLRAEIKDDNKFREIYNFAF 154
           5799************************************************************************************************* PP
   S: 103  nfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWPvliDefveyl 188
            +a++kgqksl l+tai +w+Ll+aer+++l+d+w++fL+ +++k+is+DtW +lLef k+i+++lsnYdeegaWP+liDefveyl
   Q: 155  AWAREKGQKSLPLETAIGMWRLLFAERHWPLIDHWCQFLQVRHNKAISRDTWSQLLEFVKTIDPQLSNYDEEGAWPYLIDEFVEYL 240
           ************************************************************************************96 PP

UBD/Alpha-Helix/UBA

   S: 5    dkleqlve.MGFdreealqaLraannnleaAveyLld 40
           dk++q+++ +G +++ alqaL a++++le   +y+++
   Q: 10   DKVQQFMAiTGASEKVALQALKASDWHLEGSFDYFYS 46
           89*******************************9997 PP

Organism

Aegilops tauschii

Functional Description
(View)

Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

Protein Sequence
(Fasta)

MHKLGRGSRD KVQQFMAITG ASEKVALQAL KASDWHLEGS FDYFYSQPQI SVTNSRHLED 60
LYSRYKERDA DMIMVEGTSQ LCNDLLVDPQ DVVMLVISWH MKAATMCEFT RQEFIDGLQS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTAAGCT CCTTTGCCTC CCCTTTACAT ACATATTTTC CTGCCGTGTA AACCGTGGCC 60
GCCTGATTTG GTCAGCAAAG GAATCTATGT CTAGGCCAAA CTTGGAGTAA GATCCTCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

KEGG

ats:F775_31377

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001879	Ailuropoda melanoleuca	43.09	1.00e-60	225.00
IUUC-Atr-002697	Amborella trichopoda	77.48	1.00e-51	193.00
IUUC-Apl-003933	Anas platyrhynchos	44.72	8.00e-61	226.00
IUUC-Aca-005269	Anolis carolinensis	43.72	2.00e-60	224.00
IUUC-Aly-006285	Arabidopsis lyrata	64.52	2.00e-92	330.00
IUUC-Ath-007531	Arabidopsis thaliana	70.80	5.00e-107	379.00
IUUC-Ago-007806	Ashbya gossypii	25.41	6.00e-19	87.00
IUUC-Acl-008172	Aspergillus clavatus	27.89	4.00e-28	117.00
IUUC-Afl-008569	Aspergillus flavus	30.77	4.00e-34	137.00
IUUC-Afu-009005	Aspergillus fumigatus	29.48	2.00e-21	94.70
IUUC-Ani-009241	Aspergillus nidulans	31.18	7.00e-24	103.00
IUUC-Ang-009664	Aspergillus niger	30.99	7.00e-31	126.00
IUUC-Aor-009902	Aspergillus oryzae	27.91	3.00e-12	63.20
IUUC-Ate-010414	Aspergillus terreus	29.55	8.00e-33	133.00
IUUC-Ame-011763	Astyanax mexicanus	45.12	7.00e-62	229.00
IUUC-Bgr-011991	Blumeria graminis	32.86	2.00e-25	108.00
IUUC-Bta-013561	Bos taurus	43.10	1.00e-56	211.00
IUUC-Bci-013824	Botrytis cinerea	33.60	8.00e-33	133.00
IUUC-Bdi-014138	Brachypodium distachyon	94.80	1.00e-143	501.00
IUUC-Bol-016110	Brassica oleracea	69.88	2.00e-105	374.00
IUUC-Bra-017111	Brassica rapa	69.48	1.00e-105	375.00
IUUC-Cel-018441	Caenorhabditis elegans	32.97	1.00e-38	152.00
IUUC-Cja-018854	Callithrix jacchus	45.12	2.00e-61	228.00
IUUC-Cfa-020523	Canis familiaris	42.67	3.00e-56	210.00
IUUC-Cpo-021832	Cavia porcellus	43.95	2.00e-60	224.00
IUUC-Cre-022620	Chlamydomonas reinhardtii	46.48	3.00e-66	244.00
IUUC-Csa-023108	Chlorocebus sabaeus	44.72	3.00e-61	227.00
IUUC-Cho-024373	Choloepus hoffmanni	42.68	9.00e-57	212.00
IUUC-Cin-025269	Ciona intestinalis	44.94	3.00e-61	227.00
IUUC-Csv-025976	Ciona savignyi	36.77	2.00e-34	138.00
IUUC-Cgl-026386	Colletotrichum gloeosporioides	30.94	3.00e-22	97.10
IUUC-Cne-026950	Cryptococcus neoformans	35.63	7.00e-39	153.00
IUUC-Cme-027199	Cyanidioschyzon merolae	29.45	4.00e-08	51.20
IUUC-Dre-028247	Danio rerio	44.72	2.00e-61	228.00
IUUC-Dno-028974	Dasypus novemcinctus	43.32	3.00e-61	227.00
IUUC-Dor-030143	Dipodomys ordii	45.93	1.00e-61	229.00
IUUC-Dse-031365	Dothistroma septosporum	27.13	1.00e-27	116.00
IUUC-Dme-032197	Drosophila melanogaster	41.60	6.00e-55	206.00
IUUC-Ete-032371	Echinops telfairi	43.09	1.00e-60	225.00
IUUC-Eca-033242	Equus caballus	43.09	1.00e-60	225.00
IUUC-Eeu-035317	Erinaceus europaeus	43.50	7.00e-61	226.00
IUUC-Fca-036061	Felis catus	42.91	1.00e-60	225.00
IUUC-Fal-036715	Ficedula albicollis	44.72	1.00e-60	225.00
IUUC-Fox-037884	Fusarium oxysporum	32.68	1.00e-17	82.00
IUUC-Fso-038150	Fusarium solani	30.92	3.00e-20	92.00
IUUC-Gmo-038885	Gadus morhua	45.53	1.00e-62	232.00
IUUC-Ggr-039959	Gaeumannomyces graminis	26.79	1.00e-16	80.90
IUUC-Gga-040935	Gallus gallus	42.91	1.00e-60	225.00
IUUC-Gac-041937	Gasterosteus aculeatus	43.90	1.00e-60	225.00
IUUC-Gma-043545	Glycine max	74.00	1.00e-117	414.00
IUUC-Ggo-044972	Gorilla gorilla	44.94	8.00e-62	229.00
IUUC-Hsa-046994	Homo sapiens	45.34	4.00e-62	230.00
IUUC-Hvu-047636	Hordeum vulgare	37.60	1.00e-21	95.50
IUUC-Itr-047902	Ictidomys tridecemlineatus	45.93	3.00e-62	230.00
IUUC-Kpa-049127	Komagataella pastoris	27.89	2.00e-28	118.00
IUUC-Lch-050600	Latimeria chalumnae	44.94	8.00e-63	232.00
IUUC-Lpe-051540	Leersia perrieri	92.37	2.00e-138	483.00
IUUC-Loc-052509	Lepisosteus oculatus	44.53	2.00e-61	228.00
IUUC-Lma-053103	Leptosphaeria maculans	29.44	4.00e-28	117.00
IUUC-Laf-053972	Loxodonta africana	46.34	7.00e-62	229.00
IUUC-Mcc-054700	Macaca mulatta	44.94	6.00e-62	229.00
IUUC-Meu-056535	Macropus eugenii	43.98	7.00e-47	179.00
IUUC-Mor-056909	Magnaporthe oryzae	29.06	4.00e-25	107.00
IUUC-Mpo-057299	Magnaporthe poae	26.39	2.00e-20	92.00
IUUC-Mtr-057964	Medicago truncatula	72.51	2.00e-115	407.00
IUUC-Mla-058990	Melampsora laricipopulina	26.12	1.00e-17	83.20
IUUC-Mga-060072	Meleagris gallopavo	45.12	5.00e-61	226.00
IUUC-Mvi-060312	Microbotryum violaceum	35.06	5.00e-42	163.00
IUUC-Mmr-060851	Microcebus murinus	43.09	2.00e-60	224.00
IUUC-Mdo-063074	Monodelphis domestica	43.09	7.00e-60	224.00
IUUC-Mmu-063816	Mus musculus	45.75	5.00e-63	233.00
IUUC-Mac-065016	Musa acuminata	81.01	2.00e-89	320.00
IUUC-Mpu-066870	Mustela putorius furo	42.67	3.00e-56	210.00
IUUC-Mlu-067701	Myotis lucifugus	42.68	2.00e-59	221.00
IUUC-Nfi-068610	Neosartorya fischeri	29.48	2.00e-21	94.70
IUUC-Ncr-068780	Neurospora crassa	23.90	5.00e-17	80.90
IUUC-Nle-069475	Nomascus leucogenys	44.94	8.00e-62	229.00
IUUC-Opr-070682	Ochotona princeps	45.21	7.00e-48	183.00
IUUC-Ont-071813	Oreochromis niloticus	45.12	1.00e-61	228.00
IUUC-Oan-073031	Ornithorhynchus anatinus	43.50	1.00e-60	225.00
IUUC-Ocu-074648	Oryctolagus cuniculus	43.09	1.00e-60	225.00
IUUC-Oba-074993	Oryza barthii	92.00	2.00e-138	483.00
IUUC-Obr-076341	Oryza brachyantha	89.60	2.00e-135	474.00
IUUC-Ogl-077099	Oryza glaberrima	92.00	2.00e-138	483.00
IUUC-Ogu-078285	Oryza glumaepatula	91.20	5.00e-137	479.00
IUUC-Oin-079441	Oryza indica	92.00	1.00e-138	484.00
IUUC-Olo-081037	Oryza longistaminata	92.00	1.00e-138	484.00
IUUC-Ome-081357	Oryza meridionalis	92.00	1.00e-138	484.00
IUUC-Oni-082632	Oryza nivara	91.60	6.00e-138	482.00
IUUC-Opu-083351	Oryza punctata	92.67	2.00e-129	453.00
IUUC-Oru-084306	Oryza rufipogon	92.00	1.00e-138	484.00
IUUC-Osa-085307	Oryza sativa	92.00	1.00e-138	484.00
IUUC-Ola-086371	Oryzias latipes	44.72	1.00e-61	228.00
IUUC-Olu-087646	Ostreococcus lucimarinus	41.87	1.00e-51	196.00
IUUC-Oga-088621	Otolemur garnettii	44.72	3.00e-61	227.00
IUUC-Oar-090405	Ovis aries	43.50	7.00e-61	226.00
IUUC-Ptr-091595	Pan troglodytes	44.72	5.00e-61	226.00
IUUC-Pan-092825	Papio anubis	44.94	5.00e-62	229.00
IUUC-Psi-093110	Pelodiscus sinensis	42.24	2.00e-55	207.00
IUUC-Pma-094196	Petromyzon marinus	40.32	3.00e-44	171.00
IUUC-Pno-095145	Phaeosphaeria nodorum	30.81	3.00e-24	104.00
IUUC-Ppa-095321	Physcomitrella patens	73.39	1.00e-109	388.00
IUUC-Pfo-097121	Poecilia formosa	44.31	7.00e-61	226.00
IUUC-Pab-098197	Pongo abelii	43.97	4.00e-56	210.00
IUUC-Pop-098821	Populus trichocarpa	76.52	1.00e-54	203.00
IUUC-Pca-100218	Procavia capensis	42.68	5.00e-60	223.00
IUUC-Ppe-102032	Prunus persica	74.40	5.00e-118	416.00
IUUC-Pva-102691	Pteropus vampyrus	44.94	8.00e-62	229.00
IUUC-Pgr-103633	Puccinia graminis	26.43	1.00e-19	89.70
IUUC-Ptt-103979	Puccinia triticina	36.23	1.00e-04	40.40
IUUC-Pyt-104428	Pyrenophora triticirepentis	28.29	3.00e-23	101.00
IUUC-Rno-105016	Rattus norvegicus	46.15	2.00e-63	234.00
IUUC-Sce-106358	Saccharomyces cerevisiae	23.85	9.00e-19	86.30
IUUC-Sha-106888	Sarcophilus harrisii	43.09	2.00e-60	224.00
IUUC-Sja-107938	Schizosaccharomyces japonicus	29.29	2.00e-24	105.00
IUUC-Spo-108207	Schizosaccharomyces pombe	35.18	5.00e-28	117.00
IUUC-Ssl-108410	Sclerotinia sclerotiorum	32.81	5.00e-33	134.00
IUUC-Smo-108750	Selaginella moellendorffii	65.70	2.00e-92	331.00
IUUC-Sit-110613	Setaria italica	88.80	1.00e-135	474.00
IUUC-Sly-111489	Solanum lycopersicum	75.30	7.00e-115	405.00
IUUC-Stu-112517	Solanum tuberosum	58.96	8.00e-93	332.00
IUUC-Sar-113509	Sorex araneus	41.28	1.00e-39	155.00
IUUC-Sbi-114113	Sorghum bicolor	88.40	7.00e-134	468.00
IUUC-Sre-115221	Sporisorium reilianum	26.48	1.00e-25	109.00
IUUC-Ssc-115547	Sus scrofa	43.32	3.00e-61	227.00
IUUC-Tgu-117196	Taeniopygia guttata	45.12	8.00e-61	226.00
IUUC-Tru-117740	Takifugu rubripes	44.08	2.00e-60	224.00
IUUC-Tsy-119599	Tarsius syrichta	43.09	1.00e-60	225.00
IUUC-Tni-120315	Tetraodon nigroviridis	43.09	1.00e-59	222.00
IUUC-Tca-121033	Theobroma cacao	74.50	4.00e-118	416.00
IUUC-Tre-121986	Trichoderma reesei	31.05	4.00e-20	91.30
IUUC-Tvi-122607	Trichoderma virens	31.50	2.00e-26	111.00
IUUC-Tae-125740	Triticum aestivum	85.91	3.00e-145	506.00
IUUC-Tur-126375	Triticum urartu	77.50	2.00e-139	488.00
IUUC-Tme-126878	Tuber melanosporum	33.33	5.00e-36	144.00
IUUC-Tbe-127429	Tupaia belangeri	43.94	4.00e-48	184.00
IUUC-Ttr-129086	Tursiops truncatus	38.62	6.00e-51	193.00
IUUC-Uma-129364	Ustilago maydis	28.43	2.00e-32	132.00
IUUC-Vda-129929	Verticillium dahliae	33.15	1.00e-21	97.10
IUUC-Vpa-130048	Vicugna pacos	36.99	6.00e-47	179.00
IUUC-Vvi-130834	Vitis vinifera	76.89	2.00e-119	421.00
IUUC-Xtr-131888	Xenopus tropicalis	43.90	5.00e-61	226.00
IUUC-Xma-133580	Xiphophorus maculatus	44.94	8.00e-62	229.00
IUUC-Yli-134595	Yarrowia lipolytica	33.20	7.00e-39	152.00
IUUC-Zma-135642	Zea mays	87.60	1.00e-134	471.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence