iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bol-015564

Ensembl Protein ID

Bo5g133170.1

UniProt Accession

A0A0D3CKS9; A0A0D3CKS9_BRAOL

Protein Name

Defective in cullin neddylation protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bo5g133170	Bo5g133170.1	Bo5g133170.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	5.40e-87	292.3	55	241
UBD/Alpha-Helix/UBA	1.50e-06	29.6	8	46

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkdeqkfkdiY 98
           ++++leel++rYkdp++d+i++eg++ +c dl+v+p+di++Lvl+w+++aat+cefs+eef+ gl+alg+dsi klqekl +++selkdeqkf++iY
   Q: 55   DMRRLEELYNRYKDPYSDMILAEGISVLCSDLQVEPQDIVTLVLSWHMNAATACEFSKEEFFGGLQALGVDSIGKLQEKLSFMRSELKDEQKFHEIY 151
           579********************************************************************************************** PP
   S: 99   rfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWPvliDefveyl 188
           +faf +ak+kgqksl+ldtai +w+Ll+aere++l+++w++fL+++++k+iskDtW++lLef++++++ lsnYd+egaWP+liDefveyl
   Q: 152  NFAFGWAKEKGQKSLALDTAIGMWQLLFAEREWPLVNHWCDFLQDRHNKAISKDTWAQLLEFARTVDPALSNYDAEGAWPYLIDEFVEYL 241
           ****************************************************************************************97 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlve.MGFdreealqaLraannnleaAveyLld 40
           + dkl+q+v+ +G +++ alqaL a++++leaA + +++
   Q: 8    NRDKLQQFVAiTGASDKNALQALKASDWQLEAAFDVFYS 46
           569******************************999886 PP

Organism

Brassica oleracea

Functional Description
(View)

Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

Protein Sequence
(Fasta)

MHKLSRSNRD KLQQFVAITG ASDKNALQAL KASDWQLEAA FDVFYSQPQP RSNGDMRRLE 60
ELYNRYKDPY SDMILAEGIS VLCSDLQVEP QDIVTLVLSW HMNAATACEF SKEEFFGGLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTACGCG CTTTCTCCTT TCTTTCTTCC TTCCTTCTTG CTCTGTGTTT TTTTTTTTTC 60
CGGATCCACT TAATCTCTGT ATCTGACGCT GTAAAGCTTT TGTCTTTTGA TAATTCAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006285	Arabidopsis lyrata	81.12	2.00e-115	407.00
IUUC-Ath-007531	Arabidopsis thaliana	92.80	3.00e-138	483.00
IUUC-Cel-018441	Caenorhabditis elegans	35.06	2.00e-41	162.00
IUUC-Cin-025269	Ciona intestinalis	43.32	3.00e-60	224.00
IUUC-Csv-025976	Ciona savignyi	36.16	1.00e-35	142.00
IUUC-Cme-027199	Cyanidioschyzon merolae	29.60	4.00e-07	48.50
IUUC-Lpe-051540	Leersia perrieri	70.85	1.00e-106	379.00
IUUC-Lma-053103	Leptosphaeria maculans	29.80	6.00e-26	110.00
IUUC-Ogu-078285	Oryza glumaepatula	71.37	4.00e-108	383.00
IUUC-Opu-083351	Oryza punctata	71.24	1.00e-100	358.00
IUUC-Olu-087646	Ostreococcus lucimarinus	43.90	1.00e-53	202.00
IUUC-Pfo-097121	Poecilia formosa	43.50	1.00e-58	219.00
IUUC-Pop-098821	Populus trichocarpa	84.07	6.00e-56	208.00
IUUC-Ppe-102032	Prunus persica	76.71	3.00e-117	413.00
IUUC-Sit-110052	Setaria italica	72.58	9.00e-110	389.00
IUUC-Sly-111489	Solanum lycopersicum	78.54	7.00e-118	416.00
IUUC-Sar-113248	Sorex araneus	41.71	5.00e-37	147.00
IUUC-Sbi-114113	Sorghum bicolor	72.18	3.00e-109	387.00
IUUC-Tru-117740	Takifugu rubripes	45.71	5.00e-59	220.00
IUUC-Tca-121033	Theobroma cacao	79.03	1.00e-120	424.00
IUUC-Vvi-130834	Vitis vinifera	77.11	8.00e-118	416.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence