iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118253

Ensembl Protein ID

ENSTRUP00000005742.1

UniProt Accession

H2S021; H2S021_TAKRU

Protein Name

Inhibitor of growth protein

Gene Name

ing4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000002482.1	ENSTRUT00000005777.1	ENSTRUP00000005742.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.00e-09	38.7	199	246

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C+ ewfH+aC++l+   ++p+ + w+Cp+C++
   Q: 199  TYC-LCHQVSYGE--MIGCDNtdCSiEWFHFACVGLT---TKPRGK-WYCPRCSQ 246
           69*.*******99..*****999999***********...899996.******86 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MAAGMYLEHY LDSIENLPFE LQRNFNLMRD LDQRTEDLKG QIDSLAKEYT ANARTISSEQ 60
KLSILRQIQQ SYSKCKEFGD DKVQLAMQTY EMVDKHIRRL DTDLARFEAD LKEKQIESTD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCGG GGATGTATTT GGAGCATTAT TTGGACAGTA AGATACATTA CACTTTGAAT 60
CTGTTATGAA AACGATTCCA ACTTATCTTG TTTGGTCATT TTTTTGCTCG TACCTCATAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028647--ING4
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001338	Ailuropoda melanoleuca	80.88	1.00e-106	378.00
IUUC-Atr-002906	Amborella trichopoda	33.60	2.00e-36	145.00
IUUC-Apl-004097	Anas platyrhynchos	78.40	5.00e-107	379.00
IUUC-Aca-004593	Anolis carolinensis	81.67	8.00e-113	399.00
IUUC-Ath-006578	Arabidopsis thaliana	33.85	3.00e-34	138.00
IUUC-Ame-011133	Astyanax mexicanus	88.49	1.00e-133	468.00
IUUC-Bta-012699	Bos taurus	81.27	1.00e-107	382.00
IUUC-Bdi-014504	Brachypodium distachyon	35.25	3.00e-40	158.00
IUUC-Bol-015245	Brassica oleracea	31.10	4.00e-31	128.00
IUUC-Bra-017027	Brassica rapa	31.50	5.00e-32	130.00
IUUC-Cja-019988	Callithrix jacchus	80.48	1.00e-101	362.00
IUUC-Cfa-021282	Canis familiaris	80.08	4.00e-101	360.00
IUUC-Cpo-022011	Cavia porcellus	80.88	1.00e-109	388.00
IUUC-Csa-023203	Chlorocebus sabaeus	80.48	1.00e-101	362.00
IUUC-Cin-025479	Ciona intestinalis	57.50	3.00e-78	284.00
IUUC-Csv-026288	Ciona savignyi	52.36	1.00e-74	272.00
IUUC-Dre-028264	Danio rerio	87.70	3.00e-131	460.00
IUUC-Dno-029766	Dasypus novemcinctus	77.20	2.00e-94	338.00
IUUC-Dor-031136	Dipodomys ordii	70.59	8.00e-83	299.00
IUUC-Dme-032200	Drosophila melanogaster	70.21	3.00e-39	155.00
IUUC-Eca-033565	Equus caballus	80.48	8.00e-109	385.00
IUUC-Eeu-034948	Erinaceus europaeus	67.87	2.00e-87	315.00
IUUC-Fca-036368	Felis catus	80.48	1.00e-101	362.00
IUUC-Fal-037120	Ficedula albicollis	78.00	8.00e-106	376.00
IUUC-Gmo-038982	Gadus morhua	96.41	3.00e-145	506.00
IUUC-Gga-040771	Gallus gallus	81.67	8.00e-113	399.00
IUUC-Gac-042184	Gasterosteus aculeatus	96.76	2.00e-142	497.00
IUUC-Gma-044339	Glycine max	31.23	2.00e-34	138.00
IUUC-Ggo-045559	Gorilla gorilla	80.48	1.00e-101	362.00
IUUC-Hsa-046852	Homo sapiens	80.48	1.00e-101	362.00
IUUC-Hvu-047046	Hordeum vulgare	34.25	3.00e-37	148.00
IUUC-Itr-047978	Ictidomys tridecemlineatus	80.88	3.00e-109	387.00
IUUC-Lpe-050822	Leersia perrieri	35.63	8.00e-39	153.00
IUUC-Loc-052334	Lepisosteus oculatus	70.20	6.00e-101	359.00
IUUC-Laf-054057	Loxodonta africana	80.48	1.00e-101	362.00
IUUC-Mcc-055212	Macaca mulatta	76.98	2.00e-100	358.00
IUUC-Meu-056511	Macropus eugenii	79.83	3.00e-100	357.00
IUUC-Mtr-058089	Medicago truncatula	32.81	6.00e-35	140.00
IUUC-Mga-059967	Meleagris gallopavo	79.12	3.00e-106	377.00
IUUC-Mmr-060843	Microcebus murinus	78.88	4.00e-107	380.00
IUUC-Mdo-062357	Monodelphis domestica	79.68	4.00e-108	384.00
IUUC-Mmu-064093	Mus musculus	80.88	1.00e-109	388.00
IUUC-Mpu-066923	Mustela putorius furo	69.72	1.00e-79	288.00
IUUC-Mlu-067754	Myotis lucifugus	77.87	3.00e-107	380.00
IUUC-Nle-069062	Nomascus leucogenys	80.48	1.00e-101	362.00
IUUC-Opr-070207	Ochotona princeps	74.37	6.00e-93	333.00
IUUC-Ont-072446	Oreochromis niloticus	97.21	2.00e-135	474.00
IUUC-Ocu-074235	Oryctolagus cuniculus	80.48	1.00e-101	362.00
IUUC-Obr-076266	Oryza brachyantha	34.87	2.00e-38	152.00
IUUC-Ogl-077118	Oryza glaberrima	35.50	1.00e-38	152.00
IUUC-Oin-079049	Oryza indica	35.63	6.00e-40	157.00
IUUC-Ome-081291	Oryza meridionalis	35.63	4.00e-39	154.00
IUUC-Oni-082218	Oryza nivara	35.63	6.00e-40	157.00
IUUC-Opu-084171	Oryza punctata	36.22	4.00e-38	151.00
IUUC-Osa-085563	Oryza sativa	35.63	4.00e-39	154.00
IUUC-Ola-086429	Oryzias latipes	93.23	4.00e-137	479.00
IUUC-Oga-089123	Otolemur garnettii	80.48	1.00e-101	362.00
IUUC-Oar-089524	Ovis aries	81.27	1.00e-107	382.00
IUUC-Ptr-090908	Pan troglodytes	80.48	1.00e-101	362.00
IUUC-Pan-092837	Papio anubis	80.88	1.00e-106	378.00
IUUC-Psi-093828	Pelodiscus sinensis	80.43	4.00e-102	363.00
IUUC-Ppa-096009	Physcomitrella patens	35.83	2.00e-38	152.00
IUUC-Pfo-096617	Poecilia formosa	93.63	8.00e-142	495.00
IUUC-Pab-097978	Pongo abelii	78.99	8.00e-91	326.00
IUUC-Pop-099415	Populus trichocarpa	68.25	3.00e-26	111.00
IUUC-Pca-100475	Procavia capensis	54.55	5.00e-74	270.00
IUUC-Ppe-101441	Prunus persica	32.95	2.00e-37	149.00
IUUC-Pva-102325	Pteropus vampyrus	80.48	8.00e-109	385.00
IUUC-Rno-105178	Rattus norvegicus	80.08	1.00e-115	409.00
IUUC-Sha-106773	Sarcophilus harrisii	79.68	4.00e-108	384.00
IUUC-Sly-111750	Solanum lycopersicum	32.42	6.00e-34	137.00
IUUC-Stu-112250	Solanum tuberosum	32.42	6.00e-34	137.00
IUUC-Sbi-114826	Sorghum bicolor	36.02	5.00e-37	147.00
IUUC-Sre-115124	Sporisorium reilianum	59.32	5.00e-22	99.80
IUUC-Ssc-115797	Sus scrofa	75.40	3.00e-90	324.00
IUUC-Tgu-117270	Taeniopygia guttata	81.67	8.00e-113	399.00
IUUC-Tca-121597	Theobroma cacao	32.68	9.00e-34	136.00
IUUC-Tae-123043	Triticum aestivum	33.85	8.00e-39	153.00
IUUC-Tbe-127558	Tupaia belangeri	80.88	1.00e-106	378.00
IUUC-Ttr-128300	Tursiops truncatus	77.48	2.00e-50	191.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence