iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-042086

UUCD1 version

UUC-GaA-00459

Ensembl Protein ID

ENSGACP00000012059.1

UniProt Accession

G3P386; G3P386_GASAC

Protein Name

Eukaryotic translation initiation factor 3 subunit I; Eukaryotic translation initiation factor 3 subunit 2; eIF-3-beta; eIF3 p36

Gene Name

eif3i; EIF3I; EIF3S2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000009137.1	ENSGACT00000012083.1	ENSGACP00000012059.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.50e-18	64.2	50	87

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcl..afsd.tllvsGsdDgtikvWDlrtgvll 36
           gHt+ v+c+  ++ d + +++Gs D+++++WD  tg++l
   Q: 50   GHTGAVWCVdcDW-DtKNVLTGSADNSCRLWDCQTGKQL 87
           8*******74367.4488*****************9986 PP

Organism

Gasterosteus aculeatus

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MRPILLQGHE RSITQIKYNR EGDLLFSVAK DTVTNVWYSV NGERLGTYNG HTGAVWCVDC 60
DWDTKNVLTG SADNSCRLWD CQTGKQLALL DTNSAVRTCG FDFSGNIIMF STDKQMGYQC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGGCGACCT GAAACACGAG TGCCGATCTT TTCTCTTGTT TTTTTTTTTA ACCGGAGTCT 60
GTGTGAACAC GCTGGATCGA CTGGTTACGT TTAGCTCATC AAAATGGTTC GTAGGCGTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	57.52	2.00e-33	137.00
IUUC-Aml-001321	Ailuropoda melanoleuca	83.64	5.00e-169	586.00
IUUC-Atr-002468	Amborella trichopoda	47.80	8.00e-51	193.00
IUUC-Apl-003841	Anas platyrhynchos	84.26	1.00e-170	592.00
IUUC-Aca-005123	Anolis carolinensis	82.77	4.00e-169	586.00
IUUC-Aly-006532	Arabidopsis lyrata	45.73	4.00e-83	301.00
IUUC-Ath-007094	Arabidopsis thaliana	45.73	3.00e-85	308.00
IUUC-Ago-008000	Ashbya gossypii	43.20	3.00e-80	291.00
IUUC-Acl-008098	Aspergillus clavatus	51.35	2.00e-97	348.00
IUUC-Afl-008494	Aspergillus flavus	51.07	1.00e-97	349.00
IUUC-Afu-009080	Aspergillus fumigatus	51.20	2.00e-97	348.00
IUUC-Ani-009230	Aspergillus nidulans	50.91	2.00e-96	345.00
IUUC-Aor-010114	Aspergillus oryzae	51.07	1.00e-97	349.00
IUUC-Ate-010285	Aspergillus terreus	52.13	2.00e-99	355.00
IUUC-Ame-011534	Astyanax mexicanus	89.91	0.00e+00	626.00
IUUC-Bgr-012121	Blumeria graminis	48.02	7.00e-88	317.00
IUUC-Bta-013143	Bos taurus	83.69	1.00e-169	588.00
IUUC-Bci-013950	Botrytis cinerea	51.07	3.00e-96	345.00
IUUC-Bdi-015019	Brachypodium distachyon	46.63	7.00e-87	313.00
IUUC-Bol-015709	Brassica oleracea	44.55	4.00e-81	295.00
IUUC-Bra-017760	Brassica rapa	44.55	2.00e-81	296.00
IUUC-Cel-018226	Caenorhabditis elegans	43.65	2.00e-80	292.00
IUUC-Cja-019741	Callithrix jacchus	83.69	4.00e-170	590.00
IUUC-Cfa-021204	Canis familiaris	83.33	8.00e-169	585.00
IUUC-Cpo-021661	Cavia porcellus	83.95	1.00e-169	588.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	44.86	6.00e-80	290.00
IUUC-Csa-024038	Chlorocebus sabaeus	83.69	4.00e-170	590.00
IUUC-Cin-025597	Ciona intestinalis	58.23	2.00e-115	408.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	49.39	5.00e-91	327.00
IUUC-Cne-026838	Cryptococcus neoformans	47.09	6.00e-90	323.00
IUUC-Cme-027304	Cyanidioschyzon merolae	46.42	5.00e-82	297.00
IUUC-Dre-028567	Danio rerio	91.69	0.00e+00	637.00
IUUC-Dno-029171	Dasypus novemcinctus	83.33	9.00e-169	586.00
IUUC-Dor-030257	Dipodomys ordii	73.30	2.00e-75	275.00
IUUC-Dse-031191	Dothistroma septosporum	49.40	8.00e-90	323.00
IUUC-Dme-031879	Drosophila melanogaster	59.94	4.00e-117	414.00
IUUC-Ete-032336	Echinops telfairi	79.91	1.00e-104	371.00
IUUC-Eca-033259	Equus caballus	83.64	3.00e-169	587.00
IUUC-Eeu-035153	Erinaceus europaeus	61.74	4.00e-47	181.00
IUUC-Fca-036489	Felis catus	83.64	3.00e-169	587.00
IUUC-Fal-037485	Ficedula albicollis	84.88	2.00e-171	595.00
IUUC-Fox-037860	Fusarium oxysporum	47.87	2.00e-90	325.00
IUUC-Fso-038188	Fusarium solani	48.17	4.00e-89	321.00
IUUC-Gmo-039311	Gadus morhua	91.67	0.00e+00	637.00
IUUC-Ggr-040045	Gaeumannomyces graminis	49.70	3.00e-94	338.00
IUUC-Gga-040645	Gallus gallus	82.28	4.00e-169	587.00
IUUC-Gma-043246	Glycine max	45.40	4.00e-86	311.00
IUUC-Ggo-045578	Gorilla gorilla	83.69	4.00e-170	590.00
IUUC-Hsa-046734	Homo sapiens	83.69	4.00e-170	590.00
IUUC-Hvu-047553	Hordeum vulgare	46.01	9.00e-87	313.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	83.33	7.00e-169	585.00
IUUC-Kpa-049325	Komagataella pastoris	43.73	3.00e-83	301.00
IUUC-Lch-049620	Latimeria chalumnae	83.56	5.00e-155	540.00
IUUC-Lpe-051338	Leersia perrieri	45.51	2.00e-79	288.00
IUUC-Loc-052094	Lepisosteus oculatus	82.35	3.00e-162	563.00
IUUC-Lma-053047	Leptosphaeria maculans	47.72	1.00e-89	323.00
IUUC-Laf-053801	Loxodonta africana	83.65	7.00e-166	576.00
IUUC-Mcc-055498	Macaca mulatta	73.85	1.00e-140	491.00
IUUC-Meu-056729	Macropus eugenii	76.99	4.00e-152	530.00
IUUC-Mor-057025	Magnaporthe oryzae	49.85	4.00e-92	331.00
IUUC-Mpo-057511	Magnaporthe poae	50.46	9.00e-94	336.00
IUUC-Mtr-058051	Medicago truncatula	45.71	5.00e-86	310.00
IUUC-Mla-059061	Melampsora laricipopulina	46.11	6.00e-83	300.00
IUUC-Mga-059229	Meleagris gallopavo	83.44	3.00e-168	583.00
IUUC-Mvi-060399	Microbotryum violaceum	45.78	1.00e-80	293.00
IUUC-Mmr-060764	Microcebus murinus	84.00	2.00e-170	591.00
IUUC-Mdo-062088	Monodelphis domestica	83.38	4.00e-168	583.00
IUUC-Mmu-064304	Mus musculus	84.00	3.00e-170	590.00
IUUC-Mac-065520	Musa acuminata	47.52	1.00e-87	315.00
IUUC-Mpu-066340	Mustela putorius furo	83.64	3.00e-169	587.00
IUUC-Mlu-067111	Myotis lucifugus	83.64	2.00e-169	588.00
IUUC-Nfi-068478	Neosartorya fischeri	51.20	3.00e-97	348.00
IUUC-Ncr-068820	Neurospora crassa	50.30	5.00e-93	334.00
IUUC-Nle-069903	Nomascus leucogenys	83.64	1.00e-169	588.00
IUUC-Opr-070221	Ochotona princeps	81.54	2.00e-164	571.00
IUUC-Ont-071765	Oreochromis niloticus	95.38	0.00e+00	657.00
IUUC-Oan-073660	Ornithorhynchus anatinus	82.31	4.00e-151	526.00
IUUC-Ocu-074039	Oryctolagus cuniculus	83.64	2.00e-169	587.00
IUUC-Oba-075395	Oryza barthii	39.69	1.00e-69	256.00
IUUC-Obr-076334	Oryza brachyantha	43.25	8.00e-78	283.00
IUUC-Ogl-077751	Oryza glaberrima	45.71	1.00e-84	306.00
IUUC-Ogu-078207	Oryza glumaepatula	45.85	2.00e-84	305.00
IUUC-Oin-079878	Oryza indica	46.01	7.00e-85	306.00
IUUC-Olo-080677	Oryza longistaminata	39.21	9.00e-76	276.00
IUUC-Ome-081228	Oryza meridionalis	34.98	3.00e-34	138.00
IUUC-Oni-082411	Oryza nivara	40.12	1.00e-69	256.00
IUUC-Opu-083136	Oryza punctata	45.71	2.00e-84	305.00
IUUC-Oru-084916	Oryza rufipogon	45.07	1.00e-82	299.00
IUUC-Osa-085454	Oryza sativa	46.01	7.00e-85	306.00
IUUC-Ola-087053	Oryzias latipes	91.08	0.00e+00	632.00
IUUC-Olu-087602	Ostreococcus lucimarinus	45.96	5.00e-85	307.00
IUUC-Oga-088154	Otolemur garnettii	83.33	2.00e-168	584.00
IUUC-Oar-089915	Ovis aries	83.64	5.00e-169	586.00
IUUC-Ptr-091124	Pan troglodytes	66.88	1.00e-124	439.00
IUUC-Pan-092035	Papio anubis	83.69	4.00e-170	590.00
IUUC-Psi-094096	Pelodiscus sinensis	79.26	4.00e-105	373.00
IUUC-Pno-094988	Phaeosphaeria nodorum	45.71	1.00e-80	293.00
IUUC-Ppa-095949	Physcomitrella patens	47.55	4.00e-90	324.00
IUUC-Pfo-096101	Poecilia formosa	92.62	0.00e+00	642.00
IUUC-Pab-097726	Pongo abelii	83.69	4.00e-170	590.00
IUUC-Pop-099617	Populus trichocarpa	47.55	8.00e-89	320.00
IUUC-Pca-101014	Procavia capensis	83.69	5.00e-170	589.00
IUUC-Ppe-101320	Prunus persica	46.01	9.00e-85	306.00
IUUC-Pva-102789	Pteropus vampyrus	73.85	9.00e-143	499.00
IUUC-Pgr-103479	Puccinia graminis	46.42	6.00e-83	301.00
IUUC-Ptt-103981	Puccinia triticina	47.04	1.00e-84	306.00
IUUC-Pte-104278	Pyrenophora teres	48.63	7.00e-89	320.00
IUUC-Pyt-104492	Pyrenophora triticirepentis	48.63	7.00e-89	320.00
IUUC-Rno-105867	Rattus norvegicus	66.67	1.00e-120	426.00
IUUC-Sce-106251	Saccharomyces cerevisiae	43.88	2.00e-79	289.00
IUUC-Sha-107039	Sarcophilus harrisii	83.38	3.00e-168	583.00
IUUC-Sja-107758	Schizosaccharomyces japonicus	49.85	9.00e-92	330.00
IUUC-Spo-108314	Schizosaccharomyces pombe	49.85	4.00e-90	324.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	50.30	2.00e-95	342.00
IUUC-Smo-108728	Selaginella moellendorffii	46.77	4.00e-85	307.00
IUUC-Sit-110801	Setaria italica	45.09	5.00e-84	304.00
IUUC-Sly-111326	Solanum lycopersicum	47.09	7.00e-87	313.00
IUUC-Stu-112458	Solanum tuberosum	46.93	1.00e-86	313.00
IUUC-Sbi-114063	Sorghum bicolor	44.48	7.00e-83	300.00
IUUC-Sre-115096	Sporisorium reilianum	47.16	4.00e-83	301.00
IUUC-Ssc-116080	Sus scrofa	83.69	9.00e-170	588.00
IUUC-Tgu-116988	Taeniopygia guttata	84.57	5.00e-171	593.00
IUUC-Tru-118766	Takifugu rubripes	92.92	0.00e+00	644.00
IUUC-Tni-120197	Tetraodon nigroviridis	92.62	0.00e+00	643.00
IUUC-Tca-121316	Theobroma cacao	45.71	1.00e-85	309.00
IUUC-Tre-122097	Trichoderma reesei	50.00	4.00e-92	330.00
IUUC-Tvi-122442	Trichoderma virens	50.00	1.00e-92	332.00
IUUC-Tae-125800	Triticum aestivum	46.01	1.00e-86	313.00
IUUC-Tur-126334	Triticum urartu	40.18	1.00e-67	249.00
IUUC-Tme-127038	Tuber melanosporum	51.22	1.00e-98	352.00
IUUC-Ttr-128659	Tursiops truncatus	78.09	1.00e-146	511.00
IUUC-Uma-129464	Ustilago maydis	47.16	1.00e-82	299.00
IUUC-Vda-129841	Verticillium dahliae	51.52	6.00e-95	340.00
IUUC-Vvi-131076	Vitis vinifera	46.18	3.00e-86	311.00
IUUC-Xtr-132395	Xenopus tropicalis	84.31	4.00e-170	590.00
IUUC-Xma-133383	Xiphophorus maculatus	92.31	0.00e+00	640.00
IUUC-Yli-134586	Yarrowia lipolytica	49.39	2.00e-82	299.00
IUUC-Zma-135904	Zea mays	45.09	1.00e-83	303.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence