iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bgr-012111

Ensembl Protein ID

CCU74358

UniProt Accession

N1J966; N1J966_BLUG1

Genbank Protein ID

CCU74358.1

Protein Name

NEDD8-activating enzyme E1 regulatory subunit

Genbank Nucleotide ID

CAUH01000247

Gene Name

BGHDH14_bgh01941

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
BGHDH14_bgh01941	CCU74358	CCU74358

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	6.40e-59	198.6	19	509

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllv..GagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveahee.sit 98
           YDRQ+rlw +++q++l++a +ll+  G g++G+E+lKnLvl Gvg++t++D+++v+ ++l+ +F++++ + g  +Ae++ ++l+elnp v++++h+  +++
   Q: 19   YDRQLRLWAAHGQQALEEAEILLInsGSGTVGVETLKNLVLPGVGKFTIIDDAKVCDADLGVNFFLDKNSLGSYRAECCVRHLQELNPEVKGDFHSVlDVK 119
           ***********************8446789*****************************************************************852566 PP
   S: 99   eleeeiv.FfkkfdvVvlaldnrearrkv.nrlclnarvpliesgtlGllGqvrviikgltecyscsd.....dppqktiPfctlketpn........... 181
            l ++ +   + f++V+ +   r   + +  +    +++pli++ + G++++ ++ ++ +  + + ++      ++++ +P+ +l e+ +           
   Q: 120  SL-KS-YlESRSFSFVLHTFPLRPDLLAIvQKHVATYKIPLISIHSVGFYSYFKIKLPTVLPIVDTHPefeatTDLRLLNPWKELSEYSAsltkeiktlsa 218
           66.33.224589*******999988776515666677*********************98766666666*******************6667777777776 PP
   S: 182  aaehtiewavlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv....... 274
            ++ +i++++l+ ++l+e+++ + + + l+++ek+++k+ v +++ +  eenfeeai++ +k  ++ + +s i +++++ + d+  +s+ +fw+       
   Q: 219  HKHGHIPYVALLLHFLDEWKKIHGTFP-LKYAEKKAFKEFVAAGALEVGEENFEEAIAAIMKTIKSPSLSSsILEVFEHHPEDP--ESNLSFWIivdaikq 316
           9999*******************9998.789********************************998888888999888888888..89999********** PP
   S: 275  .............................................................sfcsnaealq...........vpekvekdeevvkasap.. 301
                                                                         fc+na+ ++           ++  vek+ ++++ s +  
   Q: 317  fytrhkvlplpgsvpdmksestvyvklqniykeksrqdvaevlelvqnhpshkivskrdveDFCKNAAFVKlihpsddskldIKAIVEKELINDDPSLNlq 417
           *************************************************************7888888777665544433334444444444444444466 PP
   S: 302  ......lylllralerfekkkgrkpgelsfekdddsavdlvtaaanlraeslgiep.kldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfepl 395
                 +yl+l+a++ +++ ++ +            +++++++         +  + k+ +++ +e+a+   ++++ ++a+ gG++aqEviK++++++ p+
   Q: 418  ppsllpIYLALKAISHVSAASSTD------------ILAIIEENT------PKAAAlKVVRSVSEEVARARGGELHNISAFTGGMIAQEVIKIITKQYIPI 500
           667777777777777666666553............555555333......3344456999**************************************** PP
   S: 396  knfflfdae 404
           +n+ +fd++
   Q: 501  DNTCIFDGI 509
           ******986 PP

Organism

Blumeria graminis

Functional Description
(View)

Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

Protein Sequence
(Fasta)

MDYQNRQNAG VPIAKEQKYD RQLRLWAAHG QQALEEAEIL LINSGSGTVG VETLKNLVLP 60
GVGKFTIIDD AKVCDADLGV NFFLDKNSLG SYRAECCVRH LQELNPEVKG DFHSVLDVKS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATTACC AAAATCGCCA GAATGCCGGC GTTCCTATCG CAAAAGAGCA GAAATATGAT 60
AGACAGCTTC GTCTTTGGGC AGCACACGGG CAACAGGCAC TTGAGGAAGC CGAAATCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000764	Aegilops tauschii	32.72	5.00e-68	249.00
IUUC-Aml-002333	Ailuropoda melanoleuca	33.33	6.00e-72	263.00
IUUC-Atr-002644	Amborella trichopoda	32.41	3.00e-62	230.00
IUUC-Apl-003446	Anas platyrhynchos	31.11	7.00e-61	226.00
IUUC-Aca-004450	Anolis carolinensis	33.64	5.00e-71	259.00
IUUC-Aly-005466	Arabidopsis lyrata	32.84	1.00e-65	241.00
IUUC-Ath-006692	Arabidopsis thaliana	32.77	1.00e-66	244.00
IUUC-Ago-007900	Ashbya gossypii	27.15	3.00e-42	164.00
IUUC-Acl-008333	Aspergillus clavatus	44.96	2.00e-121	427.00
IUUC-Afl-008529	Aspergillus flavus	44.52	3.00e-119	420.00
IUUC-Afu-009071	Aspergillus fumigatus	45.34	9.00e-121	425.00
IUUC-Ani-009443	Aspergillus nidulans	43.64	2.00e-114	404.00
IUUC-Ang-009669	Aspergillus niger	46.43	2.00e-135	473.00
IUUC-Aor-009914	Aspergillus oryzae	44.80	2.00e-120	424.00
IUUC-Ate-010450	Aspergillus terreus	45.52	5.00e-123	432.00
IUUC-Ame-011183	Astyanax mexicanus	31.47	5.00e-68	249.00
IUUC-Bta-012583	Bos taurus	33.52	1.00e-72	265.00
IUUC-Bci-013892	Botrytis cinerea	57.86	9.00e-164	568.00
IUUC-Bdi-014592	Brachypodium distachyon	33.89	1.00e-69	255.00
IUUC-Bol-016401	Brassica oleracea	34.02	2.00e-70	257.00
IUUC-Bra-017506	Brassica rapa	33.58	2.00e-69	254.00
IUUC-Cel-018456	Caenorhabditis elegans	31.20	4.00e-58	216.00
IUUC-Cja-020007	Callithrix jacchus	33.39	9.00e-72	262.00
IUUC-Cfa-020324	Canis familiaris	33.58	3.00e-74	270.00
IUUC-Cpo-022248	Cavia porcellus	30.91	1.00e-36	145.00
IUUC-Csa-023149	Chlorocebus sabaeus	29.34	6.00e-45	173.00
IUUC-Cho-024537	Choloepus hoffmanni	25.37	3.00e-30	124.00
IUUC-Cin-025763	Ciona intestinalis	34.16	4.00e-74	270.00
IUUC-Csv-026113	Ciona savignyi	34.26	2.00e-74	271.00
IUUC-Cgl-026428	Colletotrichum gloeosporioides	52.42	4.00e-152	529.00
IUUC-Cne-026884	Cryptococcus neoformans	31.86	4.00e-53	200.00
IUUC-Cme-027210	Cyanidioschyzon merolae	25.65	2.00e-14	72.40
IUUC-Dre-028140	Danio rerio	31.62	4.00e-67	246.00
IUUC-Dno-030033	Dasypus novemcinctus	34.23	3.00e-63	234.00
IUUC-Dor-030513	Dipodomys ordii	55.34	2.00e-26	111.00
IUUC-Dse-031536	Dothistroma septosporum	43.47	3.00e-125	439.00
IUUC-Dme-031683	Drosophila melanogaster	33.96	3.00e-64	237.00
IUUC-Ete-032420	Echinops telfairi	28.90	2.00e-52	197.00
IUUC-Eca-033992	Equus caballus	28.98	4.00e-43	166.00
IUUC-Eeu-034713	Erinaceus europaeus	59.00	2.00e-29	122.00
IUUC-Fca-036548	Felis catus	33.64	5.00e-73	266.00
IUUC-Fal-037600	Ficedula albicollis	31.45	4.00e-59	220.00
IUUC-Fox-038037	Fusarium oxysporum	53.15	2.00e-155	540.00
IUUC-Fso-038387	Fusarium solani	52.40	7.00e-158	548.00
IUUC-Gmo-038562	Gadus morhua	32.53	6.00e-70	256.00
IUUC-Ggr-040005	Gaeumannomyces graminis	50.95	3.00e-152	530.00
IUUC-Gga-041129	Gallus gallus	32.18	6.00e-66	243.00
IUUC-Gac-042558	Gasterosteus aculeatus	31.68	3.00e-68	250.00
IUUC-Gma-043221	Glycine max	33.52	1.00e-65	242.00
IUUC-Ggo-045611	Gorilla gorilla	33.58	1.00e-71	262.00
IUUC-Hsa-046563	Homo sapiens	33.76	1.00e-73	268.00
IUUC-Hvu-047790	Hordeum vulgare	29.77	7.00e-42	162.00
IUUC-Itr-048066	Ictidomys tridecemlineatus	33.33	1.00e-71	261.00
IUUC-Kpa-049309	Komagataella pastoris	34.67	3.00e-73	266.00
IUUC-Lch-050038	Latimeria chalumnae	31.40	5.00e-68	249.00
IUUC-Lpe-051535	Leersia perrieri	30.91	7.00e-47	179.00
IUUC-Loc-051917	Lepisosteus oculatus	28.87	4.00e-54	203.00
IUUC-Lma-053112	Leptosphaeria maculans	44.48	2.00e-129	454.00
IUUC-Laf-053690	Loxodonta africana	33.64	2.00e-73	267.00
IUUC-Mcc-055117	Macaca mulatta	32.67	3.00e-67	247.00
IUUC-Meu-056761	Macropus eugenii	29.17	2.00e-34	138.00
IUUC-Mor-057230	Magnaporthe oryzae	53.85	8.00e-161	558.00
IUUC-Mpo-057514	Magnaporthe poae	52.49	4.00e-150	523.00
IUUC-Mtr-058551	Medicago truncatula	33.09	9.00e-61	226.00
IUUC-Mla-059183	Melampsora laricipopulina	34.05	5.00e-73	266.00
IUUC-Mga-060144	Meleagris gallopavo	31.05	4.00e-62	230.00
IUUC-Mvi-060221	Microbotryum violaceum	32.44	5.00e-67	246.00
IUUC-Mmr-061325	Microcebus murinus	32.36	8.00e-68	249.00
IUUC-Mdo-062532	Monodelphis domestica	33.46	5.00e-71	259.00
IUUC-Mmu-063956	Mus musculus	33.94	8.00e-74	269.00
IUUC-Mac-064521	Musa acuminata	33.89	2.00e-69	254.00
IUUC-Mpu-066716	Mustela putorius furo	34.32	1.00e-63	235.00
IUUC-Mlu-067459	Myotis lucifugus	33.15	3.00e-73	267.00
IUUC-Nfi-068245	Neosartorya fischeri	44.98	3.00e-122	430.00
IUUC-Ncr-068910	Neurospora crassa	52.35	9.00e-154	534.00
IUUC-Nle-070034	Nomascus leucogenys	31.56	2.00e-63	234.00
IUUC-Opr-070552	Ochotona princeps	32.81	1.00e-53	201.00
IUUC-Ont-071426	Oreochromis niloticus	31.39	3.00e-69	254.00
IUUC-Oan-073389	Ornithorhynchus anatinus	29.78	9.00e-41	159.00
IUUC-Ocu-074911	Oryctolagus cuniculus	33.70	3.00e-73	267.00
IUUC-Oba-075437	Oryza barthii	32.34	2.00e-55	207.00
IUUC-Obr-076684	Oryza brachyantha	32.08	4.00e-53	200.00
IUUC-Ogl-077170	Oryza glaberrima	32.34	2.00e-55	207.00
IUUC-Ogu-078844	Oryza glumaepatula	31.25	6.00e-48	183.00
IUUC-Oin-079105	Oryza indica	32.34	2.00e-55	207.00
IUUC-Olo-080943	Oryza longistaminata	30.10	9.00e-42	162.00
IUUC-Oni-082891	Oryza nivara	31.03	9.00e-50	189.00
IUUC-Opu-083457	Oryza punctata	32.52	4.00e-55	207.00
IUUC-Oru-084960	Oryza rufipogon	30.10	1.00e-41	162.00
IUUC-Osa-085358	Oryza sativa	32.46	4.00e-55	207.00
IUUC-Ola-086420	Oryzias latipes	27.93	7.00e-38	149.00
IUUC-Olu-087625	Ostreococcus lucimarinus	25.62	1.00e-40	159.00
IUUC-Oga-088810	Otolemur garnettii	33.94	6.00e-74	269.00
IUUC-Oar-089196	Ovis aries	33.15	1.00e-70	258.00
IUUC-Ptr-090617	Pan troglodytes	33.58	1.00e-72	265.00
IUUC-Pan-092761	Papio anubis	33.52	3.00e-73	267.00
IUUC-Psi-093191	Pelodiscus sinensis	30.77	1.00e-60	225.00
IUUC-Pma-094380	Petromyzon marinus	36.93	2.00e-62	231.00
IUUC-Pno-095084	Phaeosphaeria nodorum	42.19	2.00e-111	395.00
IUUC-Ppa-095798	Physcomitrella patens	30.63	9.00e-59	219.00
IUUC-Pfo-096467	Poecilia formosa	31.92	3.00e-69	254.00
IUUC-Pab-098255	Pongo abelii	34.61	1.00e-63	234.00
IUUC-Pop-099722	Populus trichocarpa	34.14	3.00e-72	264.00
IUUC-Pca-100807	Procavia capensis	37.70	6.00e-26	109.00
IUUC-Ppe-101280	Prunus persica	32.58	8.00e-69	252.00
IUUC-Pva-102333	Pteropus vampyrus	32.11	9.00e-65	239.00
IUUC-Pgr-103401	Puccinia graminis	28.92	5.00e-60	223.00
IUUC-Ptt-103889	Puccinia triticina	26.32	1.00e-54	205.00
IUUC-Pte-104355	Pyrenophora teres	44.36	6.00e-128	449.00
IUUC-Pyt-104545	Pyrenophora triticirepentis	44.54	8.00e-128	448.00
IUUC-Rno-105810	Rattus norvegicus	33.76	9.00e-73	265.00
IUUC-Sce-106397	Saccharomyces cerevisiae	22.99	7.00e-26	109.00
IUUC-Sha-106770	Sarcophilus harrisii	37.46	1.00e-43	167.00
IUUC-Sja-107926	Schizosaccharomyces japonicus	32.50	3.00e-66	244.00
IUUC-Spo-108276	Schizosaccharomyces pombe	32.89	1.00e-69	254.00
IUUC-Ssl-108387	Sclerotinia sclerotiorum	59.42	9.00e-176	607.00
IUUC-Smo-109213	Selaginella moellendorffii	32.34	2.00e-64	238.00
IUUC-Sit-110157	Setaria italica	33.15	7.00e-70	256.00
IUUC-Sly-111105	Solanum lycopersicum	32.18	2.00e-65	241.00
IUUC-Stu-112469	Solanum tuberosum	31.57	6.00e-67	246.00
IUUC-Sar-113083	Sorex araneus	39.87	2.00e-22	98.60
IUUC-Sbi-113813	Sorghum bicolor	32.84	1.00e-68	251.00
IUUC-Sre-115058	Sporisorium reilianum	34.87	1.00e-53	202.00
IUUC-Tgu-116772	Taeniopygia guttata	31.15	2.00e-60	224.00
IUUC-Tru-118686	Takifugu rubripes	31.09	2.00e-66	244.00
IUUC-Tsy-119111	Tarsius syrichta	34.97	8.00e-37	146.00
IUUC-Tni-120231	Tetraodon nigroviridis	29.01	7.00e-53	199.00
IUUC-Tca-121491	Theobroma cacao	33.58	1.00e-63	235.00
IUUC-Tre-122103	Trichoderma reesei	55.32	9.00e-165	571.00
IUUC-Tvi-122672	Trichoderma virens	53.65	4.00e-155	539.00
IUUC-Tae-125455	Triticum aestivum	33.27	4.00e-70	256.00
IUUC-Tur-126487	Triticum urartu	31.72	1.00e-63	235.00
IUUC-Tme-127097	Tuber melanosporum	38.71	5.00e-88	316.00
IUUC-Ttr-128465	Tursiops truncatus	31.22	7.00e-60	223.00
IUUC-Uma-129645	Ustilago maydis	35.42	2.00e-55	208.00
IUUC-Vda-129989	Verticillium dahliae	46.46	4.00e-119	419.00
IUUC-Vpa-130529	Vicugna pacos	31.15	9.00e-62	229.00
IUUC-Vvi-131059	Vitis vinifera	31.90	2.00e-65	241.00
IUUC-Xtr-132002	Xenopus tropicalis	33.58	2.00e-72	264.00
IUUC-Xma-133930	Xiphophorus maculatus	31.57	4.00e-68	250.00
IUUC-Yli-134505	Yarrowia lipolytica	37.26	2.00e-84	304.00
IUUC-Zma-135619	Zea mays	32.66	1.00e-66	245.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence