iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003700

Ensembl Protein ID

ENSAPLP00000003113.1

UniProt Accession

U3I792; U3I792_ANAPL

Genbank Protein ID

ENSAPLP00000003113

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01060375

Gene Name

PHIP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000003512.1	ENSAPLT00000003708.1	ENSAPLP00000003113.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.20e-34	114.1	118	155
UBD/Beta-Prp	3.70e-52	177.0	217	478

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+ f  + +++ +GsdD+ +k+W +++g+ll
   Q: 118  GHLSSVYCVTFdRTgRRIFTGSDDCLVKIWATDDGRLL 155
           8**********955599*****************9987 PP

UBD/Beta-Prp

   S: 19   spdksllatgsrdgtikvwdvttgkl......lrslsgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsv 97
           s +k++l ++++dgti  w ++ g+l       +  +   ++v+ ++  fs  g +l+tgs+D++i+v+     +++ ++ l+ h+d+v
   Q: 217  SGSKRYLSSTGADGTICFWLWDAGTLkinprpTKFTERPRPGVQMICssFSAGGMFLATGSTDHIIRVYffGSGQPEKISELEFHTDKV 305
           67899***********999999999988888544447777777755522778888**************777779999*********** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
            s++fs s++++vsGs+d t+r+w+ + +++ +                  +++++  v++v+++  +n ++++ ++ t+++W++ tg+
   Q: 306  DSIQFSNSSSRFVSGSRDGTARIWQFKRREWKSIlldmatrpagqnpqgvEDKITKLKVTMVAWDRHDNSVITAVNNMTLKVWNSFTGQ 394
           ********************************99***************888888889******************************* PP
   S: 171  llrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           l++ l g h+d v  l+   fd+  + l s+++dg v++wdl +g  +r++ +         v + + sp++++++++ s+g + i+
   Q: 395  LIHILMG-HEDEVFVLEphpFDP--RVLFSAGHDGNVIVWDLARGVKIRSYFNMIegqghGAVFDCKCSPDGQHFACTDSHGHLLIF 478
           ******9.*********999999..89******************999998875544445566667777999999999999988887 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

VKYYRHLAPD HLLQICHRLG PLLEQEIPQS VPGVQTLLGA GRQSLLRTNK SCKHVVWKGS 60
ALAALHCGRP PESPVNYGSP PSIVDTLFSR KLNGKYRLER LVPTAVYQHM KMHKRILGHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAAATATT ACAGACATTT GGCACCTGAT CACTTGCTTC AAATATGTCA TCGACTAGGA 60
CCACTTCTAG AGCAAGAAAT TCCCCAAAGT GTCCCTGGAG TGCAGACGCT ATTAGGAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR028738--PHIP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0007010--P:cytoskeleton organization
GO:0008286--P:insulin receptor signaling pathway
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0022604--P:regulation of cell morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001113	Aegilops tauschii	30.51	1.00e-52	202.00
IUUC-Aml-002299	Ailuropoda melanoleuca	86.66	0.00e+00	2848.00
IUUC-Atr-002600	Amborella trichopoda	33.20	7.00e-64	239.00
IUUC-Aca-004474	Anolis carolinensis	84.91	0.00e+00	2884.00
IUUC-Aly-006517	Arabidopsis lyrata	29.43	1.00e-61	232.00
IUUC-Ath-006801	Arabidopsis thaliana	34.79	2.00e-64	241.00
IUUC-Bta-013125	Bos taurus	86.42	0.00e+00	2831.00
IUUC-Bdi-014797	Brachypodium distachyon	33.07	4.00e-55	210.00
IUUC-Bol-016525	Brassica oleracea	29.62	3.00e-61	230.00
IUUC-Bra-017961	Brassica rapa	33.79	1.00e-67	251.00
IUUC-Cja-018868	Callithrix jacchus	84.63	0.00e+00	2865.00
IUUC-Cfa-021179	Canis familiaris	86.32	0.00e+00	2794.00
IUUC-Cpo-022077	Cavia porcellus	81.84	0.00e+00	2777.00
IUUC-Cre-023003	Chlamydomonas reinhardtii	51.00	1.00e-24	108.00
IUUC-Csa-023618	Chlorocebus sabaeus	86.37	0.00e+00	2895.00
IUUC-Cho-024794	Choloepus hoffmanni	85.87	0.00e+00	838.00
IUUC-Csv-025813	Ciona savignyi	43.87	5.00e-170	590.00
IUUC-Dno-030048	Dasypus novemcinctus	86.38	0.00e+00	2839.00
IUUC-Dor-030195	Dipodomys ordii	85.62	0.00e+00	1400.00
IUUC-Dme-031752	Drosophila melanogaster	51.85	3.00e-173	603.00
IUUC-Eca-034274	Equus caballus	86.48	0.00e+00	2853.00
IUUC-Eeu-034688	Erinaceus europaeus	91.63	0.00e+00	1276.00
IUUC-Fca-035451	Felis catus	85.85	0.00e+00	2756.00
IUUC-Fal-037465	Ficedula albicollis	96.22	0.00e+00	3163.00
IUUC-Gmo-039451	Gadus morhua	67.98	0.00e+00	714.00
IUUC-Gga-040798	Gallus gallus	96.50	0.00e+00	3204.00
IUUC-Gma-043340	Glycine max	35.25	1.00e-66	248.00
IUUC-Ggo-045347	Gorilla gorilla	85.54	0.00e+00	2881.00
IUUC-Hsa-046757	Homo sapiens	86.48	0.00e+00	2872.00
IUUC-Hvu-047706	Hordeum vulgare	31.48	2.00e-37	149.00
IUUC-Itr-048843	Ictidomys tridecemlineatus	76.32	0.00e+00	948.00
IUUC-Lpe-051619	Leersia perrieri	31.07	9.00e-63	236.00
IUUC-Loc-052672	Lepisosteus oculatus	71.52	0.00e+00	2364.00
IUUC-Laf-054140	Loxodonta africana	86.21	0.00e+00	2907.00
IUUC-Mcc-055061	Macaca mulatta	86.48	0.00e+00	2898.00
IUUC-Mtr-058094	Medicago truncatula	33.39	4.00e-65	243.00
IUUC-Mmr-060837	Microcebus murinus	86.82	0.00e+00	2859.00
IUUC-Mdo-061903	Monodelphis domestica	87.27	0.00e+00	2938.00
IUUC-Mmu-063772	Mus musculus	85.86	0.00e+00	2867.00
IUUC-Mac-065413	Musa acuminata	30.41	1.00e-36	147.00
IUUC-Mpu-066359	Mustela putorius furo	86.02	0.00e+00	2646.00
IUUC-Mlu-067928	Myotis lucifugus	86.20	0.00e+00	2847.00
IUUC-Nle-070094	Nomascus leucogenys	86.59	0.00e+00	2878.00
IUUC-Opr-070971	Ochotona princeps	69.47	0.00e+00	897.00
IUUC-Ont-072221	Oreochromis niloticus	75.31	0.00e+00	1230.00
IUUC-Oan-073185	Ornithorhynchus anatinus	85.08	0.00e+00	2796.00
IUUC-Ocu-074033	Oryctolagus cuniculus	85.76	0.00e+00	2620.00
IUUC-Oba-075709	Oryza barthii	31.37	8.00e-56	213.00
IUUC-Obr-076619	Oryza brachyantha	30.61	1.00e-62	235.00
IUUC-Oin-079669	Oryza indica	31.22	4.00e-52	199.00
IUUC-Olo-080755	Oryza longistaminata	31.86	2.00e-54	208.00
IUUC-Opu-083233	Oryza punctata	29.11	1.00e-56	215.00
IUUC-Oru-085195	Oryza rufipogon	31.37	9.00e-56	212.00
IUUC-Olu-087745	Ostreococcus lucimarinus	26.68	1.00e-52	202.00
IUUC-Oga-088578	Otolemur garnettii	85.87	0.00e+00	2842.00
IUUC-Oar-090247	Ovis aries	86.64	0.00e+00	2833.00
IUUC-Ptr-091266	Pan troglodytes	86.31	0.00e+00	2857.00
IUUC-Pan-092734	Papio anubis	86.54	0.00e+00	2901.00
IUUC-Pma-094427	Petromyzon marinus	68.03	4.00e-105	374.00
IUUC-Ppa-095793	Physcomitrella patens	31.01	5.00e-63	236.00
IUUC-Pfo-096191	Poecilia formosa	72.24	0.00e+00	2001.00
IUUC-Pab-098402	Pongo abelii	86.59	0.00e+00	2879.00
IUUC-Pop-099185	Populus trichocarpa	36.44	2.00e-70	261.00
IUUC-Pca-101128	Procavia capensis	78.40	0.00e+00	2576.00
IUUC-Ppe-101849	Prunus persica	31.18	3.00e-65	244.00
IUUC-Rno-106013	Rattus norvegicus	84.51	0.00e+00	2850.00
IUUC-Sha-107496	Sarcophilus harrisii	87.57	0.00e+00	2948.00
IUUC-Sit-110017	Setaria italica	31.50	7.00e-55	209.00
IUUC-Sly-111348	Solanum lycopersicum	32.03	1.00e-65	245.00
IUUC-Sar-113520	Sorex araneus	78.66	0.00e+00	1288.00
IUUC-Sbi-114195	Sorghum bicolor	29.87	4.00e-51	196.00
IUUC-Ssc-115461	Sus scrofa	83.04	0.00e+00	2717.00
IUUC-Tgu-116821	Taeniopygia guttata	96.11	0.00e+00	3163.00
IUUC-Tsy-119132	Tarsius syrichta	75.37	0.00e+00	2309.00
IUUC-Tca-121615	Theobroma cacao	31.90	7.00e-60	226.00
IUUC-Tae-125478	Triticum aestivum	30.82	2.00e-62	234.00
IUUC-Tur-126809	Triticum urartu	30.81	2.00e-60	228.00
IUUC-Tbe-127479	Tupaia belangeri	80.44	0.00e+00	1261.00
IUUC-Vpa-130160	Vicugna pacos	83.44	0.00e+00	2734.00
IUUC-Vvi-131332	Vitis vinifera	30.94	2.00e-66	248.00
IUUC-Xtr-132717	Xenopus tropicalis	74.89	0.00e+00	2488.00
IUUC-Xma-134120	Xiphophorus maculatus	78.35	0.00e+00	1194.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence